ONTOLOGY REPORT - ANNOTATIONS
Term: positive regulation of T-helper cell differentiation
Accession: GO:0045624
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Definition: Any process that activates or increases the frequency, rate or extent of T-helper cell differentiation.
Comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms: exact_synonym: up regulation of T-helper cell differentiation; upregulation of T-helper cell differentiation
narrow_synonym: activation of T-helper cell differentiation; stimulation of T-helper cell differentiation
related_synonym: positive regulation of T-helper cell development
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Myb
MYB proto-oncogene, transcription factor
involved_in
ISO
(PMID:20484083)
RGD
PMID:20484083
NCBI chr 1:16,658,178...16,690,135
Ensembl chr 1:16,659,442...16,687,817
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Shb
SH2 domain containing adaptor protein B
acts_upstream_of_or_within
ISO
MGI:3721903 (MGI:5617929|PMID:24645804)
RGD
PMID:24645804
MGI:5617929
NCBI chr 5:60,970,650...61,077,881
Ensembl chr 5:60,971,257...61,077,627
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Anxa1
annexin A1
involved_in
ISO IBA ISS
(PMID:17008549) PMID:21873635 GO_REF:0000024
RGD UniProt
PMID:17008549 , PMID:21873635 , PMID:21873635
GO_REF:0000024, RGD:13792537 , RGD:13792537
NCBI chr 1:237,893,983...237,910,002
Ensembl chr 1:237,893,966...237,910,012
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Ccl19
C-C motif chemokine ligand 19
involved_in
ISO
(MGI:3576832|PMID:15845453)
RGD
PMID:15845453
MGI:3576832
NCBI chr 5:58,181,025...58,182,969
Ensembl chr 5:58,181,026...58,183,017
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Hlx
H2.0-like homeobox
acts_upstream_of_or_within
ISO
MGI:105367|MGI:2182089 (MGI:3761239|PMID:16424184)
RGD
PMID:16424184
MGI:3761239
NCBI chr13:102,637,967...102,643,376
Ensembl chr13:102,637,769...102,643,223
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Ripk2
receptor-interacting serine-threonine kinase 2
acts_upstream_of_or_within
ISO
MGI:2446070 (MGI:2176424|PMID:11894097)
RGD
PMID:11894097
MGI:2176424
NCBI chr 5:29,838,713...29,870,390
Ensembl chr 5:29,838,747...29,870,735
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Socs5
suppressor of cytokine signaling 5
involved_in
ISO
(MGI:3687909|PMID:12242343)
RGD
PMID:12242343
MGI:3687909
NCBI chr 6:10,671,311...10,705,610
Ensembl chr 6:10,674,371...10,704,977
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Malt1
MALT1 paracaspase
involved_in
ISO
(MGI:6142401|PMID:25282160)
RGD
PMID:25282160
MGI:6142401
NCBI chr18:61,108,712...61,162,446
Ensembl chr18:61,109,069...61,162,445
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Mir326
microRNA 326
acts_upstream_of_or_within
ISO
(MGI:4436838|PMID:19838199)
RGD
PMID:19838199
MGI:4436838
NCBI chr 1:164,518,401...164,518,495
Ensembl chr 1:164,518,401...164,518,495
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Nfkbid
NFKB inhibitor delta
involved_in
ISO
(MGI:6142401|PMID:25282160)
RGD
PMID:25282160
MGI:6142401
NCBI chr 1:88,883,816...88,892,543
Ensembl chr 1:88,885,937...88,892,615
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Nfkbiz
NFKB inhibitor zeta
involved_in
ISO
(MGI:6142401|PMID:25282160)
RGD
PMID:25282160
MGI:6142401
NCBI chr11:47,243,342...47,271,487
Ensembl chr11:47,243,342...47,271,487
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Nlrp3
NLR family, pyrin domain containing 3
involved_in
ISO
(MGI:5689221|PMID:26098997)
RGD
PMID:26098997
MGI:5689221
NCBI chr10:45,884,324...45,918,290
Ensembl chr10:45,893,018...45,918,254
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Il23a
interleukin 23 subunit alpha
involved_in
ISO IBA
(MGI:3851279|PMID:19501566) PMID:21873635
RGD
PMID:19501566 , PMID:21873635 , PMID:21873635
MGI:3851279 , RGD:13792537 , RGD:13792537
NCBI chr 7:2,710,609...2,712,723
Ensembl chr 7:2,710,609...2,712,723
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Il18
interleukin 18
involved_in
IEA ISO
GO_REF:0000107 (MGI:3608083|PMID:12829194)
Ensembl RGD
PMID:12829194
GO_REF:0000107 MGI:3608083
NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
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Il4r
interleukin 4 receptor
acts_upstream_of_or_within
ISO
MGI:96109 (MGI:3761239|PMID:16424184)
RGD
PMID:16424184
MGI:3761239
NCBI chr 1:196,942,343...196,967,221
Ensembl chr 1:196,942,364...196,967,220
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Il6
interleukin 6
acts_upstream_of_or_within
ISO
(MGI:2450484|PMID:12594267)
RGD
PMID:12594267
MGI:2450484
NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
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Nlrp3
NLR family, pyrin domain containing 3
involved_in
ISO
(MGI:5689221|PMID:26098997)
RGD
PMID:26098997
MGI:5689221
NCBI chr10:45,884,324...45,918,290
Ensembl chr10:45,893,018...45,918,254
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Prkcz
protein kinase C, zeta
involved_in
ISS ISO
GO_REF:0000024 (MGI:3584076|PMID:15987782)
UniProt RGD
PMID:15987782
GO_REF:0000024 MGI:3584076
NCBI chr 5:172,658,071...172,769,492
Ensembl chr 5:172,658,748...172,769,421
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Rara
retinoic acid receptor, alpha
involved_in
ISO
(PMID:18416830)
RGD
PMID:18416830
NCBI chr10:86,838,819...86,884,224
Ensembl chr10:86,860,685...86,884,210
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Tnfsf4
TNF superfamily member 4
involved_in
ISO
(MGI:4943387|PMID:18354165)
RGD
PMID:18354165
MGI:4943387
NCBI chr13:79,269,973...79,293,775
Ensembl chr13:79,269,973...79,293,778
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