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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of epidermal cell differentiation
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Accession:GO:0045605 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal cell differentiation.
Synonyms:exact_synonym: down regulation of epidermal cell differentiation;   downregulation of epidermal cell differentiation
 narrow_synonym: inhibition of epidermal cell differentiation
 related_synonym: negative regulation of hypodermal cell differentiation

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negative regulation of epidermal cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DLL1 delta like canonical Notch ligand 1 involved_in ISO (MGI:3793982|PMID:17960184) UniProt PMID:17960184 MGI:3793982 NCBI chr13:97,928,480...97,936,594
Ensembl chr13:97,928,634...97,936,589 		JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19303854) Ensembl
MGI		 PMID:19303854 GO_REF:0000107 NCBI chr21:117,380,518...117,515,224
Ensembl chr21:117,380,361...117,421,573 		JBrowse link
G GDF3 growth differentiation factor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:7,727,818...7,733,514
Ensembl chr11:7,727,913...7,733,075 		JBrowse link
negative regulation of inner ear auditory receptor cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DLL1 delta like canonical Notch ligand 1 acts_upstream_of_or_within ISO (PMID:16495313) MGI PMID:16495313 NCBI chr13:97,928,480...97,936,594
Ensembl chr13:97,928,634...97,936,589 		JBrowse link
G FGFR3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO (PMID:17117437) MGI PMID:17117437 NCBI chr27:46,958,444...46,974,032
Ensembl chr27:46,957,254...46,973,392 		JBrowse link
G HES1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11023859), (PMID:11425898)
(PMID:21300049)		 Ensembl
MGI		 PMID:11023859 PMID:11425898 PMID:21300049 GO_REF:0000107 NCBI chr15:88,220,093...88,222,563
Ensembl chr15:88,220,083...88,223,243 		JBrowse link
G HES5 hes family bHLH transcription factor 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21300049)
(PMID:11425898)		 Ensembl
MGI		 PMID:11425898 PMID:21300049 GO_REF:0000107 NCBI chr20:129,023,750...129,028,790
Ensembl chr20:129,027,370...129,028,065 		JBrowse link
G NOTCH1 notch receptor 1 acts_upstream_of_or_within ISO (PMID:25535395) MGI PMID:25535395 NCBI chr12:1,656,815...1,707,566
Ensembl chr12:1,656,918...1,709,585 		JBrowse link
negative regulation of keratinocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EXTL3 exostosin like glycosyltransferase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:26,729,772...26,861,953
Ensembl chr 8:26,821,141...26,864,926 		JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19303854) Ensembl
MGI		 PMID:19303854 GO_REF:0000107 NCBI chr21:117,380,518...117,515,224
Ensembl chr21:117,380,361...117,421,573 		JBrowse link
G LOC103219985 regenerating islet-derived protein 3-alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:28,066,706...28,069,762
Ensembl chr14:28,066,956...28,069,798 		JBrowse link
G LOC103226327 homeobox protein Hox-A6 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:11435435) MGI
Ensembl		 PMID:11435435 GO_REF:0000107 NCBI chr21:31,208,988...31,215,227
Ensembl chr21:31,221,230...31,223,278
Ensembl chr21:31,221,230...31,223,278 		JBrowse link
G MSX2 msh homeobox 2 acts_upstream_of_or_within ISO (PMID:19769717) MGI PMID:19769717 NCBI chr23:76,873,499...76,879,935
Ensembl chr23:76,873,669...76,879,553 		JBrowse link
G OVOL2 ovo like zinc finger 2 involved_in ISO (PMID:19700410) BHF-UCL PMID:19700410 NCBI chr 2:47,082,294...47,118,880
Ensembl chr 2:47,082,167...47,117,521 		JBrowse link
G REG3G regenerating family member 3 gamma involved_in ISO (MGI:5488867|PMID:22727489), (PMID:22727489) UniProt PMID:22727489 MGI:5488867 NCBI chr14:28,213,731...28,217,299 JBrowse link
G SRSF6 serine and arginine rich splicing factor 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:20,340,163...20,345,873
Ensembl chr 2:20,342,681...20,346,122 		JBrowse link
G TP63 tumor protein p63 acts_upstream_of_or_within ISO (PMID:22274697) MGI PMID:22274697 NCBI chr15:83,861,489...84,126,675 JBrowse link
G TP63 tumor protein p63 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr15:84,093,957...84,123,905 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17080
    negative regulation of biological process 5650
      negative regulation of developmental process 995
        negative regulation of epidermis development 16
          negative regulation of epidermal cell differentiation 16
            negative regulation of inner ear auditory receptor cell differentiation + 5
            negative regulation of keratinocyte differentiation 10
Path 2
Term Annotations click to browse term
  biological_process 17080
    developmental process 6685
      anatomical structure development 6282
        tissue development 2214
          epithelium development 1387
            epithelial cell differentiation 806
              epidermal cell differentiation 232
                regulation of epidermal cell differentiation 62
                  negative regulation of epidermal cell differentiation 16
                    negative regulation of inner ear auditory receptor cell differentiation + 5
                    negative regulation of keratinocyte differentiation 10
paths to the root