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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of epidermal cell differentiation
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Accession:GO:0045605 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal cell differentiation.
Synonyms:exact_synonym: down regulation of epidermal cell differentiation;   downregulation of epidermal cell differentiation
 narrow_synonym: inhibition of epidermal cell differentiation
 related_synonym: negative regulation of hypodermal cell differentiation



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negative regulation of epidermal cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DLL1 delta like canonical Notch ligand 1 involved_in ISO (MGI:3793982|PMID:17960184) UniProt PMID:17960184 MGI:3793982 NCBI chr12:72,265,078...72,272,347
Ensembl chr12:72,265,682...72,272,348
JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:19303854) Ensembl
MGI
PMID:19303854 GO_REF:0000107 NCBI chr16:1,926,443...1,991,995
Ensembl chr16:1,925,956...1,991,838
JBrowse link
G GDF3 growth differentiation factor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:37,125,845...37,129,567
Ensembl chr27:37,125,928...37,129,484
JBrowse link
negative regulation of inner ear auditory receptor cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DLL1 delta like canonical Notch ligand 1 acts_upstream_of_or_within ISO (PMID:16495313) MGI PMID:16495313 NCBI chr12:72,265,078...72,272,347
Ensembl chr12:72,265,682...72,272,348
JBrowse link
G FGFR3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO (PMID:17117437) MGI PMID:17117437 NCBI chr 3:62,309,128...62,318,932
Ensembl chr 3:62,303,756...62,323,896
JBrowse link
G HES1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:21300049)
(PMID:11023859), (PMID:11425898)
Ensembl
MGI
PMID:11023859 PMID:11425898 PMID:21300049 GO_REF:0000107
G HES5 hes family bHLH transcription factor 5 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:11425898)
(PMID:21300049)
Ensembl
MGI
PMID:11425898 PMID:21300049 GO_REF:0000107 NCBI chr 5:57,387,961...57,389,412
Ensembl chr 5:57,388,674...57,389,388
JBrowse link
G NOTCH1 notch receptor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:25535395) Ensembl
MGI
PMID:25535395 GO_REF:0000107 NCBI chr 9:48,975,972...49,018,985
Ensembl chr 9:48,974,757...49,017,277
JBrowse link
negative regulation of keratinocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EXTL3 exostosin like glycosyltransferase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:28,788,803...28,833,964
Ensembl chr25:28,790,506...28,937,647
JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:19303854) Ensembl
MGI
PMID:19303854 GO_REF:0000107 NCBI chr16:1,926,443...1,991,995
Ensembl chr16:1,925,956...1,991,838
JBrowse link
G HOXA7 homeobox A7 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:11435435) MGI
Ensembl
PMID:11435435 GO_REF:0000107 NCBI chr14:40,327,918...40,334,073
Ensembl chr14:40,329,127...40,330,842
JBrowse link
G MSX2 msh homeobox 2 acts_upstream_of_or_within ISO (PMID:19769717) MGI PMID:19769717 NCBI chr 4:38,002,724...38,007,407
Ensembl chr 4:38,002,428...38,007,407
JBrowse link
G OVOL2 ovo like zinc finger 2 involved_in ISO (PMID:19700410) BHF-UCL PMID:19700410 NCBI chr24:5,020,608...5,050,487
Ensembl chr24:5,020,813...5,050,309
JBrowse link
G REG3A regenerating islet-derived 3 alpha involved_in ISO (MGI:5488867|PMID:22727489), (PMID:22727489) UniProt PMID:22727489 MGI:5488867 NCBI chr17:44,859,106...44,864,793
Ensembl chr17:44,859,137...44,861,899
JBrowse link
G SRSF6 serine and arginine rich splicing factor 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:31,217,190...31,222,852
Ensembl chr24:31,217,184...31,218,618
JBrowse link
G TP63 tumor protein p63 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:22274697) Ensembl
MGI
PMID:22274697 GO_REF:0000107 NCBI chr34:21,766,861...21,985,095
Ensembl chr34:21,766,496...21,983,046
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17068
    negative regulation of biological process 5555
      negative regulation of developmental process 1065
        negative regulation of epidermis development 14
          negative regulation of epidermal cell differentiation 14
            negative regulation of inner ear auditory receptor cell differentiation + 5
            negative regulation of keratinocyte differentiation 8
Path 2
Term Annotations click to browse term
  biological_process 17068
    developmental process 6529
      anatomical structure development 6154
        tissue development 2177
          epithelium development 1356
            epithelial cell differentiation 772
              epidermal cell differentiation 206
                regulation of epidermal cell differentiation 61
                  negative regulation of epidermal cell differentiation 14
                    negative regulation of inner ear auditory receptor cell differentiation + 5
                    negative regulation of keratinocyte differentiation 8
paths to the root