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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of epidermal cell differentiation
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Accession:GO:0045604 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of epidermal cell differentiation.
Synonyms:related_synonym: regulation of hypodermal cell differentiation


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regulation of epidermal cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KEAP1 kelch like ECH associated protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15087497) Ensembl
MGI		 PMID:15087497 GO_REF:0000107 NCBI chr20:50,651,070...50,661,178
Ensembl chr20:50,650,711...50,658,496 		JBrowse link
G KLF7 KLF transcription factor 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr37:15,515,563...15,607,345
Ensembl chr37:15,521,622...15,605,824 		JBrowse link
G MAFF MAF bZIP transcription factor F involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15087497) Ensembl
MGI
TreeGrafter		 PMID:15087497 GO_REF:0000107 GO_REF:0000118 NCBI chr10:26,475,478...26,486,109
Ensembl chr10:26,476,851...26,485,931 		JBrowse link
G MAFG MAF bZIP transcription factor G involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15087497) Ensembl
TreeGrafter
MGI		 PMID:15087497 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:368,102...373,825
Ensembl chr 9:372,216...372,797 		JBrowse link
negative regulation of epidermal cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DLL1 delta like canonical Notch ligand 1 involved_in ISO (MGI:3793982|PMID:17960184) UniProt PMID:17960184 MGI:3793982 NCBI chr12:72,265,078...72,272,347
Ensembl chr12:72,265,682...72,272,348 		JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19303854) Ensembl
MGI		 PMID:19303854 GO_REF:0000107 NCBI chr16:1,926,443...1,991,995
Ensembl chr16:1,925,956...1,991,838 		JBrowse link
G GDF3 growth differentiation factor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:37,125,845...37,129,567
Ensembl chr27:37,125,928...37,129,484 		JBrowse link
negative regulation of inner ear auditory receptor cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DLL1 delta like canonical Notch ligand 1 acts_upstream_of_or_within ISO (PMID:16495313) MGI PMID:16495313 NCBI chr12:72,265,078...72,272,347
Ensembl chr12:72,265,682...72,272,348 		JBrowse link
G FGFR3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO (PMID:17117437) MGI PMID:17117437 NCBI chr 3:62,309,128...62,318,932
Ensembl chr 3:62,303,756...62,323,896 		JBrowse link
G HES1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21300049)
(PMID:11023859), (PMID:11425898)		 Ensembl
MGI		 PMID:11023859 PMID:11425898 PMID:21300049 GO_REF:0000107
G HES5 hes family bHLH transcription factor 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11425898)
(PMID:21300049)		 Ensembl
MGI		 PMID:11425898 PMID:21300049 GO_REF:0000107 NCBI chr 5:57,387,961...57,389,412
Ensembl chr 5:57,388,674...57,389,388 		JBrowse link
G NOTCH1 notch receptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25535395) Ensembl
MGI		 PMID:25535395 GO_REF:0000107 NCBI chr 9:48,975,972...49,018,985
Ensembl chr 9:48,974,757...49,017,277 		JBrowse link
negative regulation of keratinocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EXTL3 exostosin like glycosyltransferase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:28,788,803...28,833,964
Ensembl chr25:28,790,506...28,937,647 		JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19303854) Ensembl
MGI		 PMID:19303854 GO_REF:0000107 NCBI chr16:1,926,443...1,991,995
Ensembl chr16:1,925,956...1,991,838 		JBrowse link
G HOXA7 homeobox A7 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:11435435) MGI
Ensembl		 PMID:11435435 GO_REF:0000107 NCBI chr14:40,327,918...40,334,073
Ensembl chr14:40,329,127...40,330,842 		JBrowse link
G MSX2 msh homeobox 2 acts_upstream_of_or_within ISO (PMID:19769717) MGI PMID:19769717 NCBI chr 4:38,002,724...38,007,407
Ensembl chr 4:38,002,428...38,007,407 		JBrowse link
G OVOL2 ovo like zinc finger 2 involved_in ISO (PMID:19700410) BHF-UCL PMID:19700410 NCBI chr24:5,020,608...5,050,487
Ensembl chr24:5,020,813...5,050,309 		JBrowse link
G REG3A regenerating islet-derived 3 alpha involved_in ISO (MGI:5488867|PMID:22727489), (PMID:22727489) UniProt PMID:22727489 MGI:5488867 NCBI chr17:44,859,106...44,864,793
Ensembl chr17:44,859,137...44,861,899 		JBrowse link
G SRSF6 serine and arginine rich splicing factor 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:31,217,190...31,222,852
Ensembl chr24:31,217,184...31,218,618 		JBrowse link
G TP63 tumor protein p63 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22274697) Ensembl
MGI		 PMID:22274697 GO_REF:0000107 NCBI chr34:21,766,861...21,985,095
Ensembl chr34:21,766,496...21,983,046 		JBrowse link
positive regulation of epidermal cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP4 bone morphogenetic protein 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:29,997,563...30,254,307
Ensembl chr 8:29,997,569...30,004,557 		JBrowse link
G KDF1 keratinocyte differentiation factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:73,198,278...73,206,691
Ensembl chr 2:73,197,580...73,207,153 		JBrowse link
G PTCH1 patched 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24492243) Ensembl
MGI		 PMID:24492243 GO_REF:0000107 NCBI chr 1:71,246,750...71,309,036
Ensembl chr 1:71,238,195...71,305,662 		JBrowse link
G PTCH2 patched 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24492243) Ensembl
MGI		 PMID:24492243 GO_REF:0000107 NCBI chr15:15,488,357...15,503,748
Ensembl chr15:15,487,639...15,503,234 		JBrowse link
G SFN stratifin involved_in ISO (MGI:5529391|PMID:24075906) UniProt PMID:24075906 MGI:5529391 NCBI chr 2:73,268,289...73,269,663
Ensembl chr 2:73,268,791...73,269,537 		JBrowse link
G SFRP4 secreted frizzled related protein 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:12,018,049...12,028,123
Ensembl chr18:12,017,978...12,027,788 		JBrowse link
G SULT2B1 sulfotransferase family 2B member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:107,705,568...107,721,160
Ensembl chr 1:107,705,576...107,720,876 		JBrowse link
positive regulation of inner ear auditory receptor cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATOH1 atonal bHLH transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11023859), (PMID:19154718) Ensembl
MGI		 PMID:11023859 PMID:19154718 GO_REF:0000107 NCBI chr32:16,807,217...16,809,294
Ensembl chr32:16,807,336...16,808,406 		JBrowse link
G FGF2 fibroblast growth factor 2 acts_upstream_of_or_within ISO (PMID:12417662) MGI PMID:12417662 NCBI chr19:17,403,288...17,463,143
Ensembl chr19:16,994,661...17,463,151 		JBrowse link
positive regulation of keratinocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX15B arachidonate 15-lipoxygenase type B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:32,878,348...32,888,253
Ensembl chr 5:32,878,338...32,888,316 		JBrowse link
G CYP27B1 cytochrome P450 family 27 subfamily B member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:1,825,224...1,830,845
Ensembl chr10:1,826,046...1,829,911 		JBrowse link
G ETV4 ETS variant transcription factor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:19,715,259...19,731,085
Ensembl chr 9:19,715,535...19,730,456 		JBrowse link
G FOXC1 forkhead box C1 involved_in IEA Ensembl GO_REF:0000107
G MACROH2A1 macroH2A.1 histone involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:23,369,957...23,448,235
Ensembl chr11:23,370,300...23,438,219 		JBrowse link
G MACROH2A2 macroH2A.2 histone involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:21,057,935...21,087,097
Ensembl chr 4:21,057,947...21,086,730 		JBrowse link
G MED1 mediator complex subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:22,989,257...23,019,350
Ensembl chr 9:22,989,301...23,019,349 		JBrowse link
G MIR125B-1 microRNA mir-125b-1 acts_upstream_of ISO (PMID:21412257) BHF-UCL PMID:21412257 NCBI chr 5:12,097,672...12,097,732
Ensembl chr 5:12,097,658...12,097,745 		JBrowse link
G MIR125B-2 microRNA mir-125b-2 acts_upstream_of ISO (PMID:21412257) BHF-UCL PMID:21412257 NCBI chr31:13,304,980...13,305,040
Ensembl chr31:13,304,964...13,305,052 		JBrowse link
G NCOA3 nuclear receptor coactivator 3 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr24:34,585,305...34,728,674
Ensembl chr24:34,585,305...34,728,674 		JBrowse link
G NME2 non-metastatic cells 2, protein (NM23B) expressed in involved_in ISO (PMID:16862176) HGNC-UCL PMID:16862176 NCBI chr 9:27,002,114...27,005,740
Ensembl chr 9:27,001,733...27,015,934 		JBrowse link
G NOTCH1 notch receptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16618808)
(PMID:17079689)		 Ensembl
MGI		 PMID:16618808 PMID:17079689 GO_REF:0000107 NCBI chr 9:48,975,972...49,018,985
Ensembl chr 9:48,974,757...49,017,277 		JBrowse link
G NUMA1 nuclear mitotic apparatus protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:26,000,579...26,076,281
Ensembl chr21:26,037,095...26,075,549 		JBrowse link
G OVOL2 ovo like zinc finger 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24735878) Ensembl
MGI		 PMID:24735878 GO_REF:0000107 NCBI chr24:5,020,608...5,050,487
Ensembl chr24:5,020,813...5,050,309 		JBrowse link
G PLAAT4 phospholipase A and acyltransferase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:53,418,184...53,424,027
Ensembl chr18:53,418,368...53,423,886 		JBrowse link
G PRKCH protein kinase C eta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:36,185,430...36,452,893
Ensembl chr 8:36,219,212...36,451,777 		JBrowse link
G TRIM16 tripartite motif containing 16 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:39,146,505...39,167,857
Ensembl chr 5:39,148,868...39,213,203 		JBrowse link
G VDR vitamin D receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:6,852,915...6,909,466
Ensembl chr27:6,852,723...6,909,470 		JBrowse link
G ZBED2 zinc finger BED-type containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr33:16,270,536...16,271,847
Ensembl chr33:16,271,121...16,271,774 		JBrowse link
regulation of inner ear auditory receptor cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HEY1 hes related family bHLH transcription factor with YRPW motif 1 acts_upstream_of_or_within ISO (PMID:21300049) MGI PMID:21300049 NCBI chr29:27,185,191...27,188,121
Ensembl chr29:27,185,191...27,188,121 		JBrowse link
G HEY2 hes related family bHLH transcription factor with YRPW motif 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19154718) Ensembl
MGI		 PMID:19154718 GO_REF:0000107 NCBI chr 1:64,630,656...64,646,546 JBrowse link
G MYCL MYCL proto-oncogene, bHLH transcription factor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23022312) Ensembl
MGI		 PMID:23022312 GO_REF:0000107 NCBI chr15:2,975,757...3,019,313
Ensembl chr15:3,006,409...3,013,381 		JBrowse link
G MYCN MYCN proto-oncogene, bHLH transcription factor acts_upstream_of_or_within ISO (PMID:23022312) MGI PMID:23022312 NCBI chr17:11,720,857...11,724,308 JBrowse link
G NOTCH1 notch receptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25535395) Ensembl
MGI		 PMID:25535395 GO_REF:0000107 NCBI chr 9:48,975,972...49,018,985
Ensembl chr 9:48,974,757...49,017,277 		JBrowse link
regulation of inner ear auditory receptor cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ESRP1 epithelial splicing regulatory protein 1 involved_in ISO (MGI:5915403|PMID:29107558) UniProt PMID:29107558 MGI:5915403 NCBI chr29:39,322,516...39,388,363
Ensembl chr29:39,333,117...39,387,337 		JBrowse link
regulation of keratinocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA12 ATP binding cassette subfamily A member 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chr37:22,136,732...22,306,917
Ensembl chr37:22,138,245...22,405,736 		JBrowse link
G CD109 CD109 molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22490868) Ensembl
MGI		 PMID:22490868 GO_REF:0000107 NCBI chr12:35,712,589...35,839,153
Ensembl chr12:35,712,271...35,839,044 		JBrowse link
G ERRFI1 ERBB receptor feedback inhibitor 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:61,621,964...61,636,152
Ensembl chr 5:61,622,550...61,636,148 		JBrowse link
G GRHL1 grainyhead like transcription factor 1 acts_upstream_of_or_within ISO (PMID:24586629) MGI PMID:24586629 NCBI chr17:6,953,945...7,007,175
Ensembl chr17:6,953,836...7,006,134 		JBrowse link
G KRT36 keratin 36 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:21,278,755...21,282,664
Ensembl chr 9:21,276,821...21,282,465 		JBrowse link
G KRT84 keratin 84 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:2,683,826...2,692,267
Ensembl chr27:2,683,792...2,692,267 		JBrowse link
G ROCK1 Rho associated coiled-coil containing protein kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:66,862,614...67,001,538
Ensembl chr 7:66,862,608...67,142,853 		JBrowse link
G ROCK2 Rho associated coiled-coil containing protein kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:7,931,786...8,012,484
Ensembl chr17:7,934,739...8,178,707 		JBrowse link
G SGPP1 sphingosine-1-phosphate phosphatase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:38,195,649...38,228,299
Ensembl chr 8:38,197,532...38,228,406 		JBrowse link
G TNK2 tyrosine kinase non receptor 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr33:29,153,636...29,177,568
Ensembl chr33:29,152,851...29,179,718 		JBrowse link
G ZFP36 ZFP36 ring finger protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:113,815,972...113,818,093
Ensembl chr 1:113,816,273...113,818,065 		JBrowse link
G ZFP36L1 ZFP36 ring finger protein like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:42,663,287...42,668,665
Ensembl chr 8:42,664,223...42,668,514 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17917
    regulation of biological process 12078
      regulation of developmental process 2720
        regulation of epidermis development 68
          regulation of epidermal cell differentiation 61
            negative regulation of epidermal cell differentiation + 14
            positive regulation of epidermal cell differentiation + 28
            regulation of inner ear auditory receptor cell differentiation + 12
            regulation of keratinocyte differentiation + 38
Path 2
Term Annotations click to browse term
  biological_process 17917
    developmental process 6831
      anatomical structure development 6414
        tissue development 2261
          epithelium development 1400
            epithelial cell differentiation 817
              epidermal cell differentiation 232
                regulation of epidermal cell differentiation 61
                  negative regulation of epidermal cell differentiation + 14
                  positive regulation of epidermal cell differentiation + 28
                  regulation of inner ear auditory receptor cell differentiation + 12
                  regulation of keratinocyte differentiation + 38
paths to the root