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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of fat cell differentiation
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Accession:GO:0045600 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of adipocyte differentiation.
Synonyms:exact_synonym: positive regulation of adipocyte cell differentiation;   positive regulation of adipocyte differentiation;   up regulation of fat cell differentiation;   upregulation of fat cell differentiation
 narrow_synonym: activation of fat cell differentiation;   stimulation of fat cell differentiation


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positive regulation of fat cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aamdc adipogenesis associated, Mth938 domain containing involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:22279136)		 GO_Central
RGD		 PMID:22279136 GO_REF:0000033 NCBI chr 1:151,861,990...151,893,621
Ensembl chr 1:151,845,255...151,892,398 		JBrowse link
G Adig adipogenin NOT|acts_upstream_of_or_within
involved_in		 ISO (PMID:26427354)
(PMID:15567149), (PMID:16132694)		 RGD PMID:15567149 PMID:16132694 PMID:26427354 NCBI chr 3:147,155,079...147,160,412
Ensembl chr 3:147,154,097...147,160,490
Ensembl chr 3:147,154,097...147,160,490 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 involved_in ISO
IEA		 (PMID:8940145)
GO_REF:0000107		 RGD
Ensembl		 PMID:8940145 GO_REF:0000107 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Asxl2 ASXL transcriptional regulator 2 involved_in ISO (PMID:21047783) RGD PMID:21047783 NCBI chr 6:26,425,017...26,514,899
Ensembl chr 6:26,425,954...26,507,477 		JBrowse link
G Axin2 axin 2 IMP RGD PMID:23996200 RGD:151356748 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231 		JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:15175325)		 Ensembl
RGD		 PMID:15175325 GO_REF:0000107 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Carm1 coactivator-associated arginine methyltransferase 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:18188184)		 UniProt
RGD		 PMID:18188184 GO_REF:0000024 NCBI chr 8:20,097,262...20,141,950
Ensembl chr 8:20,097,254...20,147,689 		JBrowse link
G Ccdc3 coiled-coil domain containing 3 acts_upstream_of_or_within ISO (PMID:25605713) RGD PMID:25605713 NCBI chr17:73,031,891...73,135,173
Ensembl chr17:73,035,045...73,135,337 		JBrowse link
G Cds1 CDP-diacylglycerol synthase 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:26946540)		 UniProt
RGD		 PMID:26946540 GO_REF:0000024 NCBI chr14:7,820,328...7,882,943
Ensembl chr14:7,820,351...7,882,681 		JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha acts_upstream_of_or_within IMP
ISO		 (PMID:10937998) RGD PMID:10937998 PMID:11731483 RGD:1625374 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:19324970)		 UniProt
Ensembl
RGD		 PMID:19324970 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473 		JBrowse link
G Cmklr1 chemerin chemokine-like receptor 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:17635925)		 UniProt
RGD		 PMID:17635925 GO_REF:0000024 NCBI chr12:42,974,462...43,027,321
Ensembl chr12:42,974,410...43,028,129 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 involved_in ISS
ISO		 GO_REF:0000024
UniProtKB:Q32M00 (PMID:21728997)		 UniProt
RGD		 PMID:21728997 GO_REF:0000024 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Crebl2 cAMP responsive element binding protein-like 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:21728997)		 UniProt
RGD		 PMID:21728997 GO_REF:0000024 NCBI chr 4:167,673,359...167,699,299
Ensembl chr 4:167,673,315...167,699,292 		JBrowse link
G Dact1 dishevelled-binding antagonist of beta-catenin 1 acts_upstream_of_or_within ISO (PMID:19073771) RGD PMID:19073771 NCBI chr 6:89,790,676...89,818,254
Ensembl chr 6:89,790,644...89,817,906 		JBrowse link
G Dkkl1 dickkopf like acrosomal protein 1 acts_upstream_of_or_within ISO (PMID:12055200) RGD PMID:12055200 NCBI chr 1:95,694,010...95,699,259
Ensembl chr 1:95,694,010...95,699,259 		JBrowse link
G Fndc3b fibronectin type III domain containing 3B acts_upstream_of_or_within ISO MGI:4822558 (PMID:15527760), (PMID:20493170) RGD PMID:15527760 PMID:20493170 NCBI chr 2:110,311,439...110,617,504
Ensembl chr 2:110,312,694...110,547,830 		JBrowse link
G Frzb frizzled-related protein acts_upstream_of_or_within ISO (PMID:12055200) RGD PMID:12055200 NCBI chr 3:65,332,274...65,365,208
Ensembl chr 3:65,332,277...65,365,208 		JBrowse link
G Gdf3 growth differentiation factor 3 involved_in ISO (PMID:22223106) RGD PMID:22223106 NCBI chr 4:155,831,572...155,835,953
Ensembl chr 4:155,830,909...155,835,937 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A acts_upstream_of_or_within ISO (PMID:20719859) RGD PMID:20719859 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C acts_upstream_of_or_within ISO (PMID:20719859) RGD PMID:20719859 NCBI chr  X:110,640,777...110,870,288
Ensembl chr  X:110,641,153...110,870,287 		JBrowse link
G Id2 inhibitor of DNA binding 2 acts_upstream_of_or_within ISO MGI:3806370 (PMID:18562627) RGD PMID:18562627 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400 		JBrowse link
G Igf1 insulin-like growth factor 1 IDA RGD PMID:16897348 RGD:1598452 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Klf5 KLF transcription factor 5 acts_upstream_of_or_within ISO (PMID:20719859) RGD PMID:20719859 NCBI chr15:76,060,320...76,079,445
Ensembl chr15:76,064,258...76,079,445 		JBrowse link
G Lmo3 LIM domain only 3 involved_in
NOT|acts_upstream_of_or_within		 ISO (PMID:23823477) RGD PMID:23823477 NCBI chr 4:171,234,686...171,297,677
Ensembl chr 4:171,234,696...171,292,222 		JBrowse link
G Lpl lipoprotein lipase involved_in ISO
IEA		 (PMID:29794473), (PMID:31769250)
GO_REF:0000107		 RGD
Ensembl		 PMID:29794473 PMID:31769250 GO_REF:0000107 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249 		JBrowse link
G Lrp5 LDL receptor related protein 5 involved_in ISO (PMID:17680723) RGD PMID:17680723 NCBI chr 1:200,814,247...200,917,581
Ensembl chr 1:200,814,250...200,917,581 		JBrowse link
G Medag mesenteric estrogen-dependent adipogenesis involved_in ISO (PMID:22510272) RGD PMID:22510272 NCBI chr12:5,613,191...5,634,583
Ensembl chr12:5,613,208...5,634,767 		JBrowse link
G Mir106a microRNA 106a acts_upstream_of_or_within ISO (PMID:23399447) RGD PMID:23399447 NCBI chr  X:132,422,584...132,422,661
Ensembl chr  X:132,422,584...132,422,661 		JBrowse link
G Mir125a microRNA 125a IMP RGD PMID:29319166 RGD:26884461 NCBI chr 1:58,677,626...58,677,710
Ensembl chr 1:58,677,626...58,677,710 		JBrowse link
G Mir17 microRNA 17 acts_upstream_of_or_within ISO UniProtKB:P12643 (PMID:23399447) RGD PMID:23399447 NCBI chr15:92,180,629...92,180,712
Ensembl chr15:92,180,629...92,180,712 		JBrowse link
G Mir204 microRNA 204 IMP RGD PMID:29319166 RGD:26884461 NCBI chr 1:220,316,931...220,317,040
Ensembl chr 1:220,316,931...220,317,040 		JBrowse link
G Mir21 microRNA 21 involved_in ISO (PMID:19816956), (PMID:23239100) RGD PMID:19816956 PMID:23239100 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mir29b1 microRNA 29b-1 involved_in ISO (PMID:27030318) RGD PMID:27030318 NCBI chr 4:59,650,987...59,651,067
Ensembl chr 4:59,650,986...59,651,067 		JBrowse link
G Mir29b2 microRNA 29b-2 involved_in ISO (PMID:27030318) RGD PMID:27030318 NCBI chr13:106,570,371...106,570,451
Ensembl chr13:106,570,367...106,570,456 		JBrowse link
G Noct nocturnin involved_in ISS
ISO		 GO_REF:0000024
(PMID:20498072)		 UniProt
RGD		 PMID:20498072 GO_REF:0000024 NCBI chr 2:135,271,189...135,291,407
Ensembl chr 2:135,271,189...135,291,400 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma involved_in IMP
ISO		 PMID:27910957
(PMID:19324970), (PMID:21035761)		 RGD PMID:19324970 PMID:21035761 PMID:27910957 RGD:38501075 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Rarres2 retinoic acid receptor responder 2 involved_in ISO (PMID:17635925) RGD PMID:17635925 NCBI chr 4:77,522,549...77,525,733
Ensembl chr 4:77,522,535...77,525,556 		JBrowse link
G Sav1 salvador family WW domain containing protein 1 acts_upstream_of_or_within ISO MGI:1928487 (PMID:22292086) RGD PMID:22292086 NCBI chr 6:88,478,536...88,500,121
Ensembl chr 6:88,478,539...88,499,968 		JBrowse link
G Sfrp1 secreted frizzled-related protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:12055200)
(PMID:15886250)		 Ensembl
RGD		 PMID:12055200 PMID:15886250 GO_REF:0000107 NCBI chr16:68,575,763...68,614,180
Ensembl chr16:68,575,763...68,614,286 		JBrowse link
G Sfrp2 secreted frizzled-related protein 2 acts_upstream_of_or_within ISO (PMID:12055200) RGD PMID:12055200 NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063 		JBrowse link
G Sh3pxd2b SH3 and PX domains 2B involved_in ISO (PMID:18959745), (PMID:27711054) RGD PMID:18959745 PMID:27711054 NCBI chr10:16,918,611...17,027,499
Ensembl chr10:16,918,679...17,005,170 		JBrowse link
G Sirt6 sirtuin 6 involved_in ISO (PMID:28355567) RGD PMID:28355567 NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914 		JBrowse link
G Snai2 snail family transcriptional repressor 2 acts_upstream_of_or_within ISO MGI:2447176|MGI:97747 (PMID:17905753) RGD PMID:17905753 NCBI chr11:86,182,788...86,186,203
Ensembl chr11:86,181,909...86,186,200 		JBrowse link
G Stk3 serine/threonine kinase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1929004 (PMID:22292086)		 Ensembl
RGD		 PMID:22292086 GO_REF:0000107 NCBI chr 7:66,053,209...66,323,292
Ensembl chr 7:66,052,345...66,323,233 		JBrowse link
G Stk4 serine/threonine kinase 4 acts_upstream_of_or_within ISO MGI:1928487 (PMID:22292086) RGD PMID:22292086 NCBI chr 3:152,745,958...152,827,747
Ensembl chr 3:152,745,681...152,827,744 		JBrowse link
G Sult1e1 sulfotransferase family 1E member 1 involved_in ISO
IEA		 (PMID:24567372)
GO_REF:0000107		 RGD
Ensembl		 PMID:24567372 GO_REF:0000107 NCBI chr14:20,422,324...20,439,562
Ensembl chr14:20,422,324...20,439,275 		JBrowse link
G Syap1 synapse associated protein 1 involved_in ISO (PMID:23300339) RGD PMID:23300339 NCBI chr  X:31,792,180...31,826,672
Ensembl chr  X:31,792,193...31,826,667 		JBrowse link
G Tmem64 transmembrane protein 64 involved_in ISO (PMID:25979161) RGD PMID:25979161 NCBI chr 5:28,698,947...28,745,384
Ensembl chr 5:28,698,918...28,745,330 		JBrowse link
G Tph1 tryptophan hydroxylase 1 acts_upstream_of_or_within ISO (PMID:20719859) RGD PMID:20719859 NCBI chr 1:97,157,375...97,178,415
Ensembl chr 1:97,157,409...97,178,344 		JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 IMP RGD PMID:23081848 RGD:10003033 NCBI chr 1:95,781,805...95,812,095
Ensembl chr 1:95,782,000...95,812,532 		JBrowse link
G Uchl3 ubiquitin C-terminal hydrolase L3 involved_in ISO (PMID:19837878) RGD PMID:19837878 NCBI chr15:78,485,304...78,527,355
Ensembl chr15:78,485,315...78,527,355
Ensembl chr 3:78,485,315...78,527,355 		JBrowse link
G Wdfy2 WD repeat and FYVE domain containing 2 involved_in ISO
IBA		 (PMID:18388859)
GO_REF:0000033		 RGD
GO_Central		 PMID:18388859 GO_REF:0000033 NCBI chr15:37,083,842...37,209,559
Ensembl chr15:37,042,987...37,209,304 		JBrowse link
G Wif1 Wnt inhibitory factor 1 acts_upstream_of_or_within ISO (PMID:12055200) RGD PMID:12055200 NCBI chr 7:56,548,060...56,618,364
Ensembl chr 7:56,548,053...56,618,360 		JBrowse link
G Wnt5b Wnt family member 5B acts_upstream_of_or_within ISO MGI:98956 (PMID:15796911) RGD PMID:15796911 NCBI chr 4:152,609,566...152,733,790
Ensembl chr 4:152,609,569...152,733,407 		JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:23623498)		 UniProt
Ensembl
RGD		 PMID:23623498 GO_REF:0000024 GO_REF:0000107 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693 		JBrowse link
G Zbtb16 zinc finger and BTB domain containing 16 involved_in ISS
ISO		 GO_REF:0000024
(PMID:21547890)		 UniProt
RGD		 PMID:21547890 GO_REF:0000024 NCBI chr 8:48,989,376...49,177,011
Ensembl chr 8:48,994,566...49,177,011 		JBrowse link
G Zbtb7c zinc finger and BTB domain containing 7C acts_upstream_of_or_within ISO (PMID:22331133) RGD PMID:22331133 NCBI chr18:69,441,616...69,765,744
Ensembl chr18:69,441,616...69,765,297 		JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A involved_in ISO
ISS		 (PMID:22739135)
(PMID:19666473)
GO_REF:0000024		 RGD
UniProt		 PMID:19666473 PMID:22739135 GO_REF:0000024 NCBI chr 5:137,376,562...137,385,351
Ensembl chr 5:137,376,564...137,385,351 		JBrowse link
G Zfp36 zinc finger protein 36 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:22701344)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:22701344 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:83,669,084...83,671,564
Ensembl chr 1:83,669,084...83,671,564 		JBrowse link
G Zfp36l1 zinc finger protein 36, C3H type-like 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:22701344)		 UniProt
RGD		 PMID:22701344 GO_REF:0000024 NCBI chr 6:98,930,705...98,935,748
Ensembl chr 6:98,930,718...98,935,748 		JBrowse link
G Zfp385a zinc finger protein 385A acts_upstream_of_or_within ISO (PMID:18418387) RGD PMID:18418387 NCBI chr 7:134,448,914...134,475,548
Ensembl chr 7:134,448,921...134,475,548 		JBrowse link
positive regulation of brown fat cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp7 bone morphogenetic protein 7 involved_in ISO (PMID:27923061) RGD PMID:27923061 NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788 		JBrowse link
G Ffar4 free fatty acid receptor 4 involved_in ISO (PMID:29343498) RGD PMID:29343498 NCBI chr 1:235,873,576...235,891,597
Ensembl chr 1:235,873,576...235,891,597 		JBrowse link
G Fndc5 fibronectin type III domain containing 5 involved_in ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(PMID:22237023)		 UniProt
GO_Central
RGD		 PMID:22237023 GO_REF:0000024 GO_REF:0000033 NCBI chr 5:141,481,593...141,491,257
Ensembl chr 5:141,481,590...141,490,731 		JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U involved_in ISS
ISO		 GO_REF:0000024
(PMID:28784777)		 UniProt
RGD		 PMID:28784777 GO_REF:0000024 NCBI chr13:90,069,058...90,086,905
Ensembl chr13:90,074,181...90,086,588 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:23977283)		 Ensembl
RGD		 PMID:23977283 GO_REF:0000107 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589 		JBrowse link
G Mecom MDS1 and EVI1 complex locus acts_upstream_of_or_within ISO (PMID:24703692) RGD PMID:24703692 NCBI chr 2:112,909,353...113,464,583
Ensembl chr 2:112,909,321...113,464,590 		JBrowse link
G Metrnl meteorin-like, glial cell differentiation regulator involved_in ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(PMID:24906147)		 UniProt
GO_Central
RGD		 PMID:24906147 GO_REF:0000024 GO_REF:0000033 NCBI chr10:106,963,880...106,977,875
Ensembl chr10:106,963,880...106,977,869 		JBrowse link
G Napepld N-acyl phosphatidylethanolamine phospholipase D involved_in ISS
ISO		 GO_REF:0000024
(PMID:25757720)		 UniProt
RGD		 PMID:25757720 GO_REF:0000024 NCBI chr 4:13,360,532...13,398,815
Ensembl chr 4:13,361,006...13,398,748 		JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase involved_in ISS
ISO		 GO_REF:0000024
(PMID:27923061)		 UniProt
RGD		 PMID:27923061 GO_REF:0000024 NCBI chr20:7,554,921...7,559,174
Ensembl chr20:7,554,921...7,559,174 		JBrowse link
G Prdm16 PR/SET domain 16 acts_upstream_of_or_within ISO MGI:2135565|MGI:2669525|MGI:5564782 (PMID:24703692) RGD PMID:24703692 NCBI chr 5:164,879,864...165,203,986
Ensembl chr 5:164,880,587...165,203,601 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 involved_in ISO (PMID:20448152) RGD PMID:20448152 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rreb1 ras responsive element binding protein 1 involved_in ISO (PMID:27923061) RGD PMID:27923061 NCBI chr17:26,876,687...27,002,554
Ensembl chr17:26,876,697...27,002,615 		JBrowse link
G Six1 SIX homeobox 1 involved_in ISO (PMID:27923061) RGD PMID:27923061 NCBI chr 6:91,746,739...91,751,975
Ensembl chr 6:91,746,739...91,751,975 		JBrowse link
G Sox13 SRY-box transcription factor 13 involved_in ISO (PMID:27923061) RGD PMID:27923061 NCBI chr13:44,831,097...44,875,522
Ensembl chr13:44,831,085...44,875,762 		JBrowse link
G Tfe3 transcription factor binding to IGHM enhancer 3 involved_in ISO (PMID:27913603) RGD PMID:27913603 NCBI chr  X:14,729,547...14,742,830
Ensembl chr  X:14,729,550...14,742,571 		JBrowse link
G Vstm2a V-set and transmembrane domain containing 2A involved_in ISO (PMID:28052263) RGD PMID:28052263 NCBI chr14:90,660,012...90,897,561
Ensembl chr14:90,660,004...90,685,656 		JBrowse link
G Zbtb7b zinc finger and BTB domain containing 7B involved_in ISO (PMID:28784777) RGD PMID:28784777 NCBI chr 2:174,795,831...174,811,980
Ensembl chr 2:174,797,453...174,814,236 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20076
    positive regulation of biological process 6746
      positive regulation of developmental process 1565
        positive regulation of cell differentiation 1034
          positive regulation of fat cell differentiation 79
            positive regulation of brown fat cell differentiation 17
Path 2
Term Annotations click to browse term
  biological_process 20076
    cellular process 19155
      cellular developmental process 4782
        cell differentiation 4781
          fat cell differentiation 287
            regulation of fat cell differentiation 165
              positive regulation of fat cell differentiation 79
                positive regulation of brown fat cell differentiation 17
paths to the root