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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of regulatory T cell differentiation
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Accession:GO:0045591 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of differentiation of regulatory T cells.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: positive regulation of regulatory T lymphocyte differentiation;   positive regulation of suppressor T cell differentiation;   up regulation of regulatory T cell differentiation;   upregulation of regulatory T cell differentiation
 narrow_synonym: activation of regulatory T cell differentiation;   stimulation of regulatory T cell differentiation
 related_synonym: positive regulation of regulatory T cell development



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positive regulation of regulatory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ambra1 autophagy and beclin 1 regulator 1 involved_in ISO (PMID:30513302)
(MGI:6284097|PMID:30513302)
RGD PMID:30513302 MGI:6284097 NCBI chr 3:77,700,936...77,890,221
Ensembl chr 3:77,700,936...77,890,221
JBrowse link
G Bcl6 BCL6, transcription repressor involved_in ISO (PMID:20935202), (PMID:22387553) RGD PMID:20935202 PMID:22387553 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389
JBrowse link
G Btn2a2 butyrophilin, subfamily 2, member A2 acts_upstream_of_or_within ISO (PMID:23589618) RGD PMID:23589618 NCBI chr17:41,620,807...41,632,621
Ensembl chr17:41,620,839...41,632,618
JBrowse link
G Carmil2 capping protein regulator and myosin 1 linker 2 acts_upstream_of_or_within ISO MGI:4462559|MGI:5547539 (PMID:23793062) RGD PMID:23793062 NCBI chr19:33,571,255...33,586,783
Ensembl chr19:33,574,257...33,586,965
JBrowse link
G Cd46 CD46 molecule involved_in ISO (PMID:12540904) RGD PMID:12540904 NCBI chr13:106,575,586...106,606,325
Ensembl chr13:106,574,858...106,660,445
JBrowse link
G Dusp10 dual specificity phosphatase 10 involved_in ISO (PMID:22387553) RGD PMID:22387553 NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716
JBrowse link
G Foxo3 forkhead box O3 involved_in ISO (PMID:30513302) RGD PMID:30513302 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
JBrowse link
G Foxp3 forkhead box P3 involved_in
acts_upstream_of_or_within
ISO (PMID:30513302)
MGI:2654936 (PMID:12522256), (PMID:15100250), (PMID:15780990), (PMID:16769892), (PMID:17028180)
RGD PMID:12522256 PMID:15100250 PMID:15780990 PMID:16769892 PMID:17028180 More... NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838
JBrowse link
G Il2 interleukin 2 IDA RGD PMID:6233372 RGD:1600097 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il4i1 interleukin 4 induced 1 involved_in ISO (PMID:25778793)
(MGI:5753024|PMID:25778793)
RGD PMID:25778793 MGI:5753024 NCBI chr 1:95,299,457...95,324,564
Ensembl chr 1:95,295,601...95,324,562
JBrowse link
G Kat5 lysine acetyltransferase 5 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:24835996)
(MGI:5576410|PMID:24835996)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:24835996 GO_REF:0000024 GO_REF:0000107 MGI:5576410 NCBI chr 1:202,895,751...202,903,178
Ensembl chr 1:202,895,751...202,903,458
JBrowse link
G Lgals9 galectin 9 involved_in ISO (MGI:5688819|PMID:25065622) RGD PMID:25065622 MGI:5688819 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045
JBrowse link
G Lilrb4 leukocyte immunoglobulin like receptor B4 involved_in ISO (PMID:20935202), (PMID:22387553) RGD PMID:20935202 PMID:22387553 NCBI chr 1:69,805,020...69,810,628
Ensembl chr 1:69,805,250...69,810,660
JBrowse link
G Mir214 microRNA 214 IMP RGD PMID:30287503 RGD:38549580 NCBI chr13:74,588,374...74,588,481
Ensembl chr13:74,588,372...74,588,481
JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 involved_in ISO (PMID:20448110) RGD PMID:20448110 NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117
JBrowse link
G Socs1 suppressor of cytokine signaling 1 involved_in ISO
IEA
(PMID:22387553)
GO_REF:0000107
RGD
Ensembl
PMID:22387553 GO_REF:0000107 NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383
JBrowse link
G Sox12 SRY-box transcription factor 12 involved_in ISO (MGI:6203502|PMID:30190287) RGD PMID:30190287 MGI:6203502 NCBI chr 3:140,859,499...140,860,518
Ensembl chr 3:140,856,579...140,860,975
JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO (MGI:5688819|PMID:25065622) RGD PMID:25065622 MGI:5688819 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Vsir V-set immunoregulatory receptor involved_in ISO (PMID:24691993) RGD PMID:24691993 NCBI chr20:28,281,582...28,307,262
Ensembl chr20:28,281,596...28,303,878
JBrowse link
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO MGI:1857034|MGI:2654936|MGI:3696705 (PMID:12612578), (PMID:16275384), (PMID:16301745), (PMID:18573908) RGD PMID:12612578 PMID:16275384 PMID:16301745 PMID:18573908 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838
JBrowse link
G Gimap5 GTPase, IMAP family member 5 IMP RGD PMID:15778366 RGD:2303772 NCBI chr 4:77,693,417...77,701,025
Ensembl chr 4:77,687,564...77,703,086
JBrowse link
G Il2rg interleukin 2 receptor subunit gamma acts_upstream_of_or_within ISO MGI:1857455 (PMID:16227984) RGD PMID:16227984 NCBI chr  X:66,395,330...66,399,026
Ensembl chr  X:66,392,542...66,399,823
JBrowse link
G Klhl25 kelch-like family member 25 involved_in ISO
ISS
(PMID:34491895)
(MGI:6765767|PMID:34491895)
GO_REF:0000024
RGD
UniProt
PMID:34491895 GO_REF:0000024 MGI:6765767 NCBI chr 1:129,724,894...129,750,142
Ensembl chr 1:129,722,026...129,750,227
JBrowse link
G RT1-Da RT1 class II, locus Da involved_in ISO (PMID:28467828) RGD PMID:28467828 NCBI chr20:4,513,464...4,518,457
Ensembl chr20:4,512,911...4,518,455
JBrowse link
G RT1-Db1 RT1 class II, locus Db1 involved_in ISO (PMID:28467828) RGD PMID:28467828 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258
JBrowse link
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma involved_in ISO (PMID:20209097) RGD PMID:20209097 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:20209097) RGD PMID:20209097 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    immune system process 3017
      leukocyte activation 1052
        lymphocyte activation 851
          lymphocyte differentiation 448
            T cell differentiation 324
              regulatory T cell differentiation 48
                positive regulation of regulatory T cell differentiation 25
                  positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation + 8
Path 2
Term Annotations click to browse term
  biological_process 20413
    cellular process 18812
      cellular developmental process 4768
        cell differentiation 4767
          cell development 3311
            hemopoiesis 1064
              leukocyte differentiation 676
                mononuclear cell differentiation 545
                  lymphocyte differentiation 448
                    T cell differentiation 324
                      regulation of T cell differentiation 179
                        positive regulation of T cell differentiation 105
                          positive regulation of regulatory T cell differentiation 25
                            positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation + 8
paths to the root