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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of regulatory T cell differentiation
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Accession:GO:0045590 term browser browse the term
Definition:Any process that stops, prevents, or reduces the rate of differentiation of regulatory T cells.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: down regulation of regulatory T cell differentiation;   downregulation of regulatory T cell differentiation;   negative regulation of regulatory T lymphocyte differentiation;   negative regulation of suppressor T cell differentiation
 narrow_synonym: inhibition of regulatory T cell differentiation
 related_synonym: negative regulation of regulatory T cell development


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negative regulation of regulatory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd44 CD44 molecule (Indian blood group) involved_in ISO (MGI:5688819|PMID:25065622) RGD PMID:25065622 MGI:5688819 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 involved_in IBA
ISO		 PMID:21873635
(PMID:18641304)		 RGD PMID:18641304 PMID:21873635 RGD:13792537 NCBI chr 9:62,318,874...62,325,978
Ensembl chr 9:62,319,312...62,324,963 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 IMP RGD PMID:30287503 RGD:38549580 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743 		JBrowse link
G Irf1 interferon regulatory factor 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3803082|PMID:18641303)		 UniProt
RGD		 PMID:18641303 GO_REF:0000024 MGI:3803082 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166 		JBrowse link
G Lag3 lymphocyte activating 3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3510279|PMID:15485628)		 UniProt
RGD		 PMID:15485628 GO_REF:0000024 MGI:3510279 NCBI chr 4:157,712,665...157,722,229
Ensembl chr 4:157,712,667...157,720,404 		JBrowse link
G Mdk midkine involved_in ISO
ISS		 (PMID:22323540)
GO_REF:0000024		 RGD
UniProt		 PMID:22323540 GO_REF:0000024 NCBI chr 3:77,901,156...77,903,997
Ensembl chr 3:77,901,158...77,903,130 		JBrowse link
G Mir21 microRNA 21 involved_in ISO RNAcentral:URS0000338542_9606 (PMID:22387553) RGD PMID:22387553 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mir30b microRNA 30b involved_in ISO RNAcentral:URS000039ED8D_9606 (PMID:22387553) RGD PMID:22387553 NCBI chr 7:100,132,589...100,132,675
Ensembl chr 7:100,132,589...100,132,675 		JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:3806904|PMID:18713990) RGD PMID:18713990 MGI:3806904 NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788 		JBrowse link
G Tug1 taurine up-regulated 1 IMP RGD PMID:30287503 RGD:38549580 NCBI chr14:78,519,894...78,526,927
Ensembl chr14:78,522,506...78,526,927 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20094
    immune system process 2562
      leukocyte activation 1033
        lymphocyte activation 845
          lymphocyte differentiation 436
            T cell differentiation 311
              regulatory T cell differentiation 48
                negative regulation of regulatory T cell differentiation 10
                  negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation + 0
Path 2
Term Annotations click to browse term
  biological_process 20094
    cellular process 18691
      cellular developmental process 4636
        cell differentiation 4613
          cell development 3213
            hemopoiesis 1027
              leukocyte differentiation 647
                mononuclear cell differentiation 495
                  lymphocyte differentiation 436
                    T cell differentiation 311
                      regulation of T cell differentiation 179
                        negative regulation of T cell differentiation 55
                          negative regulation of regulatory T cell differentiation 10
                            negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation + 0
paths to the root