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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of cholesterol biosynthetic process
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Accession:GO:0045542 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol.
Synonyms:exact_synonym: positive regulation of cholesterol anabolism;   positive regulation of cholesterol biosynthesis;   positive regulation of cholesterol formation;   positive regulation of cholesterol synthesis;   up regulation of cholesterol biosynthetic process;   upregulation of cholesterol biosynthetic process
 narrow_synonym: activation of cholesterol biosynthetic process;   stimulation of cholesterol biosynthetic process



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positive regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCG1 ATP binding cassette subfamily G member 1 involved_in ISO (MGI:3768186|PMID:17916878) BHF-UCL PMID:17916878 MGI:3768186 NCBI chr13:205,561,897...205,628,428
Ensembl chr13:205,561,951...205,628,425
JBrowse link
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 involved_in ISO PMID:23536474 BHF-UCL PMID:23536474 RGD:13792517 NCBI chr 4:74,343,101...74,372,628
Ensembl chr 4:74,342,856...74,372,638
JBrowse link
G FDPS farnesyl diphosphate synthase ISO RGD PMID:18637708 RGD:2316295 NCBI chr 4:94,500,140...94,514,820
Ensembl chr 4:94,489,215...94,518,408
JBrowse link
G FGF1 fibroblast growth factor 1 involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 2:144,133,846...144,241,345
Ensembl chr 2:144,133,390...144,241,323
JBrowse link
G POR P450 (cytochrome) oxidoreductase ISO RGD PMID:19264869 RGD:2316785 NCBI chr 3:10,212,734...10,272,184
Ensembl chr 3:10,212,735...10,281,833
JBrowse link
G SCAP SREBF chaperone involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:30,253,262...30,320,625
Ensembl chr13:30,253,268...30,320,526
JBrowse link
G SCP2 sterol carrier protein 2 ISO RGD PMID:2554812 RGD:9850260 NCBI chr 6:159,191,045...159,314,985 JBrowse link
G SEC14L2 SEC14 like lipid binding 2 ISO RGD PMID:11226224 RGD:727312 NCBI chr14:47,369,663...47,391,335 JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
ISS
(MGI:1098057|PMID:9329978)
(MGI:3603730|PMID:16046411)
Ensembl
MGI
UniProt
PMID:9329978 PMID:16046411 GO_REF:0000024 GO_REF:0000107 MGI:1098057 MGI:3603730 NCBI chr12:60,733,967...60,750,951
Ensembl chr12:60,733,907...60,751,265
JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 involved_in ISO (PMID:32322062) UniProt PMID:32322062 NCBI chr 5:6,719,484...6,784,724
Ensembl chr 5:6,719,487...6,784,672
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16579
    metabolic process 10421
      positive regulation of metabolic process 3710
        positive regulation of small molecule metabolic process 158
          positive regulation of cholesterol metabolic process 11
            positive regulation of cholesterol biosynthetic process 10
Path 2
Term Annotations click to browse term
  biological_process 16579
    biological regulation 12069
      regulation of biological process 11444
        regulation of metabolic process 6297
          regulation of primary metabolic process 5349
            regulation of lipid metabolic process 360
              regulation of steroid metabolic process 108
                regulation of steroid biosynthetic process 78
                  regulation of sterol biosynthetic process 19
                    regulation of cholesterol biosynthetic process 19
                      positive regulation of cholesterol biosynthetic process 10
paths to the root