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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of cholesterol biosynthetic process
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Accession:GO:0045542 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol.
Synonyms:exact_synonym: positive regulation of cholesterol anabolism;   positive regulation of cholesterol biosynthesis;   positive regulation of cholesterol formation;   positive regulation of cholesterol synthesis;   up regulation of cholesterol biosynthetic process;   upregulation of cholesterol biosynthetic process
 narrow_synonym: activation of cholesterol biosynthetic process;   stimulation of cholesterol biosynthetic process


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positive regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCG1 ATP binding cassette subfamily G member 1 involved_in ISO (MGI:3768186|PMID:17916878) BHF-UCL PMID:17916878 MGI:3768186 NCBI chr31:36,574,406...36,627,598
Ensembl chr31:36,553,380...36,620,043
JBrowse link
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 involved_in ISO PMID:23536474 BHF-UCL PMID:23536474 RGD:13792517 NCBI chr29:9,285,315...9,295,895
Ensembl chr29:9,286,181...9,332,310
JBrowse link
G FDPS farnesyl diphosphate synthase ISO RGD PMID:18637708 RGD:2316295 NCBI chr 7:42,241,086...42,250,373
Ensembl chr 7:42,241,107...42,250,225
JBrowse link
G FGF1 fibroblast growth factor 1 involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 2:37,467,431...37,554,770
Ensembl chr 2:37,470,985...37,554,619
JBrowse link
G LOC477539 SEC14-like protein 2 ISO RGD PMID:11226224 RGD:727312 NCBI chr26:23,542,555...23,563,579 JBrowse link
G POR cytochrome p450 oxidoreductase ISO RGD PMID:19264869 RGD:2316785 NCBI chr 6:7,247,780...7,316,282
Ensembl chr 6:7,263,574...7,316,297
JBrowse link
G SCAP SREBF chaperone involved_in ISO (PMID:32322062) UniProt PMID:32322062 NCBI chr20:41,418,507...41,485,681
Ensembl chr20:41,418,536...41,487,024
JBrowse link
G SCP2 sterol carrier protein 2 ISO RGD PMID:2554812 RGD:9850260 NCBI chr 5:55,860,053...55,971,657
Ensembl chr 5:55,860,549...55,964,014
JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 acts_upstream_of_or_within
involved_in
ISO (MGI:1098057|PMID:9329978)
(PMID:32322062)
(MGI:3623165|PMID:9062341), (MGI:83216|PMID:8833906)
(MGI:3603730|PMID:16046411)
MGI
UniProt
PMID:8833906 PMID:9062341 PMID:9329978 PMID:16046411 PMID:32322062 MGI:1098057 MGI:3603730 MGI:3623165 MGI:83216 NCBI chr 5:41,663,809...41,686,764
Ensembl chr 5:41,663,773...41,686,776
JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 involved_in ISO (PMID:32322062) UniProt PMID:32322062 NCBI chr10:23,451,923...23,532,765
Ensembl chr10:23,452,561...23,518,689
Ensembl chr10:23,452,561...23,518,689
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 13863
    metabolic process 8966
      positive regulation of metabolic process 3524
        positive regulation of small molecule metabolic process 156
          positive regulation of cholesterol metabolic process 11
            positive regulation of cholesterol biosynthetic process 10
Path 2
Term Annotations click to browse term
  biological_process 13863
    biological regulation 10007
      regulation of biological process 9447
        regulation of metabolic process 5649
          regulation of primary metabolic process 4728
            regulation of lipid metabolic process 357
              regulation of steroid metabolic process 104
                regulation of steroid biosynthetic process 75
                  regulation of sterol biosynthetic process 19
                    regulation of cholesterol biosynthetic process 19
                      positive regulation of cholesterol biosynthetic process 10
paths to the root