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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of cholesterol biosynthetic process
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Accession:GO:0045542 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol.
Synonyms:exact_synonym: positive regulation of cholesterol anabolism;   positive regulation of cholesterol biosynthesis;   positive regulation of cholesterol formation;   positive regulation of cholesterol synthesis;   up regulation of cholesterol biosynthetic process;   upregulation of cholesterol biosynthetic process
 narrow_synonym: activation of cholesterol biosynthetic process;   stimulation of cholesterol biosynthetic process


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positive regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCG1 ATP binding cassette subfamily G member 1 involved_in ISO (MGI:3768186|PMID:17916878) BHF-UCL PMID:17916878 MGI:3768186 NCBI chr21:28,534,697...28,619,590
Ensembl chr21:41,839,115...41,933,050
JBrowse link
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 involved_in ISO PMID:23536474 BHF-UCL PMID:23536474 RGD:13792517 NCBI chr 8:54,942,509...54,952,500
Ensembl chr 8:56,593,799...56,604,037
JBrowse link
G FDPS farnesyl diphosphate synthase ISO RGD PMID:18637708 RGD:2316295 NCBI chr 1:130,653,316...130,665,196
Ensembl chr 1:134,258,968...134,270,237
JBrowse link
G FGF1 fibroblast growth factor 1 involved_in ISO (PMID:19229075) BHF-UCL PMID:19229075 NCBI chr 5:137,949,100...138,054,553
Ensembl chr 5:144,056,387...144,078,001
JBrowse link
G LOC100990437 NADPH--cytochrome P450 reductase ISO RGD PMID:19264869 RGD:2316785 NCBI chr 7:68,035,021...68,105,934
Ensembl chr 7:82,364,418...82,437,530
JBrowse link
G SCAP SREBF chaperone involved_in ISO (PMID:32322062) UniProt PMID:32322062 NCBI chr 3:47,314,535...47,379,455
Ensembl chr 3:48,414,012...48,479,845
JBrowse link
G SCP2 sterol carrier protein 2 ISO RGD PMID:2554812 RGD:9850260 NCBI chr 1:52,195,491...52,324,227
Ensembl chr 1:53,797,254...53,924,939
JBrowse link
G SEC14L2 SEC14 like lipid binding 2 ISO RGD PMID:11226224 RGD:727312 NCBI chr22:11,432,608...11,460,973
Ensembl chr22:29,234,162...29,261,937
JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 involved_in
acts_upstream_of_or_within
ISO (PMID:32322062)
(MGI:1098057|PMID:9329978)
(MGI:3623165|PMID:9062341), (MGI:83216|PMID:8833906)
(MGI:3603730|PMID:16046411)
UniProt
MGI
PMID:8833906 PMID:9062341 PMID:9329978 PMID:16046411 PMID:32322062 MGI:1098057 MGI:3603730 MGI:3623165 MGI:83216 NCBI chr17:33,458,196...33,484,643
Ensembl chr17:38,405,794...38,432,045
JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 involved_in ISO (PMID:32322062) UniProt PMID:32322062 NCBI chr22:22,725,790...22,799,749
Ensembl chr22:40,811,459...40,884,947
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12657
    metabolic process 7931
      positive regulation of metabolic process 3372
        positive regulation of small molecule metabolic process 150
          positive regulation of cholesterol metabolic process 10
            positive regulation of cholesterol biosynthetic process 10
Path 2
Term Annotations click to browse term
  biological_process 12657
    biological regulation 9218
      regulation of biological process 8712
        regulation of metabolic process 5178
          regulation of primary metabolic process 4371
            regulation of lipid metabolic process 352
              regulation of steroid metabolic process 103
                regulation of steroid biosynthetic process 74
                  regulation of sterol biosynthetic process 20
                    regulation of cholesterol biosynthetic process 20
                      positive regulation of cholesterol biosynthetic process 10
paths to the root