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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of cholesterol biosynthetic process
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Accession:GO:0045542 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol.
Synonyms:exact_synonym: positive regulation of cholesterol anabolism;   positive regulation of cholesterol biosynthesis;   positive regulation of cholesterol formation;   positive regulation of cholesterol synthesis;   up regulation of cholesterol biosynthetic process;   upregulation of cholesterol biosynthetic process
 narrow_synonym: activation of cholesterol biosynthetic process;   stimulation of cholesterol biosynthetic process



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positive regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg1 ATP binding cassette subfamily G member 1 involved_in ISO (MGI:3768186|PMID:17916878) RGD PMID:17916878 MGI:3768186 NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
JBrowse link
G Abcg4 ATP binding cassette subfamily G member 4 involved_in ISO
IEA
(MGI:3768186|PMID:17916878)
GO_REF:0000107
RGD
Ensembl
PMID:17916878 GO_REF:0000107 MGI:3768186 NCBI chr 8:44,611,187...44,629,818
Ensembl chr 8:44,611,187...44,626,881
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 involved_in IDA PMID:23536474 BHF-UCL PMID:23536474 RGD:13792517 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
JBrowse link
G Fdps farnesyl diphosphate synthase IMP RGD PMID:18637708 RGD:2316295 NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776
JBrowse link
G Fgf1 fibroblast growth factor 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:19229075)
UniProt
RGD
PMID:19229075 GO_REF:0000024 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
JBrowse link
G Mir96 microRNA 96 involved_in
acts_upstream_of
ISO RNAcentral:URS00001CC379_9606 (PMID:23823476)
(PMID:30460077)
RGD PMID:23823476 PMID:30460077 NCBI chr 4:58,788,411...58,788,516
Ensembl chr 4:58,788,411...58,788,516
JBrowse link
G Por cytochrome p450 oxidoreductase IMP RGD PMID:19264869 RGD:2316785 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link
G Qki QKI, KH domain containing RNA binding involved_in ISO (MGI:6712091|PMID:33942715) RGD PMID:33942715 MGI:6712091 NCBI chr 1:50,387,716...50,501,568
Ensembl chr 1:50,387,698...50,498,831
JBrowse link
G Scap SREBF chaperone involved_in ISO (PMID:32322062) RGD PMID:32322062 NCBI chr 8:110,306,026...110,360,677
Ensembl chr 8:110,306,031...110,360,666
JBrowse link
G Scp2 sterol carrier protein 2 IDA RGD PMID:2554812 RGD:9850260 NCBI chr 5:122,806,949...122,881,259
Ensembl chr 5:122,776,549...122,881,287
JBrowse link
G Sec14l2 SEC14-like lipid binding 2 IDA RGD PMID:11226224 RGD:727312 NCBI chr14:78,973,805...78,998,480
Ensembl chr14:78,973,808...78,993,788
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 acts_upstream_of_or_within
involved_in
ISO
ISS
MGI:2177958|MGI:2177959 (MGI:1098057|PMID:9329978), (MGI:3603730|PMID:16046411)
(MGI:3623165|PMID:9062341), (MGI:83216|PMID:8833906)
(PMID:12177166)
(PMID:32322062)
GO_REF:0000024
RGD
UniProt
PMID:8833906 PMID:9062341 PMID:9329978 PMID:12177166 PMID:16046411 More... GO_REF:0000024 MGI:1098057 MGI:3603730 MGI:3623165 MGI:83216 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:12177166)
(PMID:32322062)
GO_REF:0000024
(MGI:6712091|PMID:33942715), (MGI:6713934|PMID:34021134)
Ensembl
RGD
UniProt
PMID:12177166 PMID:32322062 PMID:33942715 PMID:34021134 GO_REF:0000024 GO_REF:0000107 MGI:6712091 MGI:6713934 NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20325
    metabolic process 11737
      positive regulation of metabolic process 3805
        positive regulation of small molecule metabolic process 170
          positive regulation of cholesterol metabolic process 17
            positive regulation of cholesterol biosynthetic process 13
Path 2
Term Annotations click to browse term
  biological_process 20325
    biological regulation 13633
      regulation of biological process 13227
        regulation of metabolic process 6585
          regulation of primary metabolic process 5431
            regulation of lipid metabolic process 375
              regulation of steroid metabolic process 116
                regulation of steroid biosynthetic process 90
                  regulation of sterol biosynthetic process 29
                    regulation of cholesterol biosynthetic process 29
                      positive regulation of cholesterol biosynthetic process 13
paths to the root