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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of cholesterol biosynthetic process
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Accession:GO:0045541 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol.
Synonyms:exact_synonym: down regulation of cholesterol biosynthetic process;   downregulation of cholesterol biosynthetic process;   negative regulation of cholesterol anabolism;   negative regulation of cholesterol biosynthesis;   negative regulation of cholesterol formation;   negative regulation of cholesterol synthesis
 narrow_synonym: inhibition of cholesterol biosynthetic process


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negative regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in ISO (PMID:1917954) RGD
BHF-UCL
PMID:1917954 PMID:9225228 RGD:10059686 NCBI chrNW_004936706:1,512,438...1,516,805 JBrowse link
G Erlin1 ER lipid raft associated 1 involved_in ISO (PMID:24217618) UniProt PMID:24217618 NCBI chrNW_004936636:80,583...116,027 JBrowse link
G Erlin2 ER lipid raft associated 2 involved_in ISO (PMID:24217618) UniProt PMID:24217618 NCBI chrNW_004936710:1,193,679...1,210,059 JBrowse link
G Idi2 isopentenyl-diphosphate delta isomerase 2 acts_upstream_of_or_within ISO (MGI:5490819|PMID:17202134) MGI PMID:17202134 MGI:5490819 NCBI chrNW_004936484:13,086,928...13,092,291 JBrowse link
G Sod1 superoxide dismutase 1 involved_in ISO (PMID:15473258) UniProt PMID:15473258 NCBI chrNW_004936500:10,345,154...10,352,873 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12171
    metabolic process 7647
      negative regulation of metabolic process 2495
        negative regulation of small molecule metabolic process 92
          negative regulation of cholesterol metabolic process 5
            negative regulation of cholesterol biosynthetic process 5
Path 2
Term Annotations click to browse term
  biological_process 12171
    biological regulation 8884
      regulation of biological process 8415
        regulation of metabolic process 5000
          regulation of primary metabolic process 4242
            regulation of lipid metabolic process 346
              regulation of steroid metabolic process 101
                regulation of steroid biosynthetic process 74
                  regulation of sterol biosynthetic process 20
                    regulation of cholesterol biosynthetic process 20
                      negative regulation of cholesterol biosynthetic process 5
paths to the root