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Term:negative regulation of cholesterol biosynthetic process
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Accession:GO:0045541 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol.
Synonyms:exact_synonym: down regulation of cholesterol biosynthetic process;   downregulation of cholesterol biosynthetic process;   negative regulation of cholesterol anabolism;   negative regulation of cholesterol biosynthesis;   negative regulation of cholesterol formation;   negative regulation of cholesterol synthesis
 narrow_synonym: inhibition of cholesterol biosynthetic process

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negative regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E involved_in IDA
(PMID:1917954) BHF-UCL
PMID:1917954 PMID:9225228 RGD:10059686 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393
JBrowse link
G ERLIN1 ER lipid raft associated 1 involved_in IMP (PMID:24217618) UniProt PMID:24217618 NCBI chr10:100,150,094...100,186,029
Ensembl chr10:100,150,094...100,186,033
JBrowse link
G ERLIN2 ER lipid raft associated 2 involved_in IMP (PMID:24217618) UniProt PMID:24217618 NCBI chr 8:37,736,627...37,758,422
Ensembl chr 8:37,736,601...37,758,422
JBrowse link
G IDI2 isopentenyl-diphosphate delta isomerase 2 acts_upstream_of_or_within ISO (MGI:5490819|PMID:17202134) MGI PMID:17202134 MGI:5490819 NCBI chr10:1,018,910...1,025,859
Ensembl chr10:1,018,910...1,025,859
JBrowse link
G SCAP SREBF chaperone involved_in NAS (PMID:11969205) UniProt PMID:11969205 NCBI chr 3:47,413,681...47,477,126
Ensembl chr 3:47,413,681...47,477,126
JBrowse link
G SOD1 superoxide dismutase 1 involved_in IDA (PMID:15473258) UniProt PMID:15473258 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18537
    metabolic process 11867
      negative regulation of metabolic process 3367
        negative regulation of small molecule metabolic process 113
          negative regulation of cholesterol metabolic process 6
            negative regulation of cholesterol biosynthetic process 6
Path 2
Term Annotations click to browse term
  biological_process 18537
    biological regulation 13081
      regulation of biological process 12367
        regulation of metabolic process 7180
          regulation of primary metabolic process 6063
            regulation of lipid metabolic process 392
              regulation of steroid metabolic process 118
                regulation of steroid biosynthetic process 84
                  regulation of sterol biosynthetic process 23
                    regulation of cholesterol biosynthetic process 23
                      negative regulation of cholesterol biosynthetic process 6
paths to the root