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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of cholesterol biosynthetic process
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Accession:GO:0045541 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol.
Synonyms:exact_synonym: down regulation of cholesterol biosynthetic process;   downregulation of cholesterol biosynthetic process;   negative regulation of cholesterol anabolism;   negative regulation of cholesterol biosynthesis;   negative regulation of cholesterol formation;   negative regulation of cholesterol synthesis
 narrow_synonym: inhibition of cholesterol biosynthetic process


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negative regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E involved_in ISO (PMID:1917954) RGD
BHF-UCL
PMID:1917954 PMID:9225228 RGD:10059686 NCBI chr 1:110,525,717...110,528,534
Ensembl chr 1:110,525,722...110,528,440
JBrowse link
G ERLIN1 ER lipid raft associated 1 involved_in ISO (PMID:24217618) UniProt PMID:24217618 NCBI chr28:12,924,942...12,962,016
Ensembl chr28:12,927,018...12,961,983
JBrowse link
G ERLIN2 ER lipid raft associated 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:27,622,549...27,639,807
Ensembl chr16:27,625,417...27,639,202
JBrowse link
G SOD1 superoxide dismutase 1 involved_in ISO (PMID:15473258) UniProt PMID:15473258 NCBI chr31:26,540,291...26,544,212
Ensembl chr31:26,486,274...26,662,815
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 13863
    metabolic process 8966
      negative regulation of metabolic process 2789
        negative regulation of small molecule metabolic process 95
          negative regulation of cholesterol metabolic process 4
            negative regulation of cholesterol biosynthetic process 4
Path 2
Term Annotations click to browse term
  biological_process 13863
    biological regulation 10007
      regulation of biological process 9447
        regulation of metabolic process 5649
          regulation of primary metabolic process 4728
            regulation of lipid metabolic process 357
              regulation of steroid metabolic process 104
                regulation of steroid biosynthetic process 75
                  regulation of sterol biosynthetic process 19
                    regulation of cholesterol biosynthetic process 19
                      negative regulation of cholesterol biosynthetic process 4
paths to the root