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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of cholesterol biosynthetic process
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Accession:GO:0045541 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol.
Synonyms:exact_synonym: down regulation of cholesterol biosynthetic process;   downregulation of cholesterol biosynthetic process;   negative regulation of cholesterol anabolism;   negative regulation of cholesterol biosynthesis;   negative regulation of cholesterol formation;   negative regulation of cholesterol synthesis
 narrow_synonym: inhibition of cholesterol biosynthetic process


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negative regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in IDA
IEA
ISO		 GO_REF:0000107
(PMID:1917954)		 Ensembl
RGD		 PMID:1917954 PMID:9225228 GO_REF:0000107, RGD:10059686 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Erlin1 ER lipid raft associated 1 involved_in ISO (PMID:24217618) RGD PMID:24217618 NCBI chr 1:242,921,147...242,956,472
Ensembl chr 1:242,921,152...242,956,394 		JBrowse link
G Erlin2 ER lipid raft associated 2 involved_in ISO (PMID:24217618) RGD PMID:24217618 NCBI chr16:65,017,654...65,034,184
Ensembl chr16:65,018,532...65,033,671 		JBrowse link
G Idi2 isopentenyl-diphosphate delta isomerase 2 acts_upstream_of_or_within ISO (PMID:17202134) RGD PMID:17202134 NCBI chr17:61,331,385...61,334,987
Ensembl chr17:61,331,669...61,334,285 		JBrowse link
G Mir185 microRNA 185 acts_upstream_of ISO RNAcentral:URS00002367FA_9606|RNAcentral:URS00004176D4_9606 (PMID:23951060), (PMID:24296663) RGD PMID:23951060 PMID:24296663 NCBI chr11:82,664,716...82,664,795
Ensembl chr11:82,664,716...82,664,795 		JBrowse link
G Mir342 microRNA 342 acts_upstream_of ISO (PMID:23951060) RGD PMID:23951060 NCBI chr 6:127,565,269...127,565,367
Ensembl chr 6:127,565,269...127,565,367 		JBrowse link
G Mir98 microRNA 98 involved_in ISO (PMID:30195495) RGD PMID:30195495 NCBI chr  X:20,981,235...20,981,342
Ensembl chr  X:20,981,235...20,981,342 		JBrowse link
G Sod1 superoxide dismutase 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:15473258)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:15473258 GO_REF:0000024 GO_REF:0000107 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    metabolic process 11835
      negative regulation of metabolic process 3098
        negative regulation of small molecule metabolic process 126
          negative regulation of cholesterol metabolic process 9
            negative regulation of cholesterol biosynthetic process 8
Path 2
Term Annotations click to browse term
  biological_process 20413
    biological regulation 13755
      regulation of biological process 13322
        regulation of metabolic process 6641
          regulation of primary metabolic process 5455
            regulation of lipid metabolic process 375
              regulation of steroid metabolic process 117
                regulation of steroid biosynthetic process 91
                  regulation of sterol biosynthetic process 30
                    regulation of cholesterol biosynthetic process 30
                      negative regulation of cholesterol biosynthetic process 8
paths to the root