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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of cholesterol biosynthetic process
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Accession:GO:0045541 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol.
Synonyms:exact_synonym: down regulation of cholesterol biosynthetic process;   downregulation of cholesterol biosynthetic process;   negative regulation of cholesterol anabolism;   negative regulation of cholesterol biosynthesis;   negative regulation of cholesterol formation;   negative regulation of cholesterol synthesis
 narrow_synonym: inhibition of cholesterol biosynthetic process


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negative regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in IDA
ISO
IEA
(PMID:1917954)
GO_REF:0000107
RGD
Ensembl
PMID:1917954 PMID:9225228 GO_REF:0000107, RGD:10059686 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Erlin1 ER lipid raft associated 1 involved_in ISO (PMID:24217618) RGD PMID:24217618 NCBI chr 1:242,921,147...242,956,472
Ensembl chr 1:242,921,152...242,956,394
JBrowse link
G Erlin2 ER lipid raft associated 2 involved_in ISO (PMID:24217618) RGD PMID:24217618 NCBI chr16:65,017,654...65,034,184
Ensembl chr16:65,018,532...65,033,671
JBrowse link
G Idi2 isopentenyl-diphosphate delta isomerase 2 acts_upstream_of_or_within ISO (MGI:5490819|PMID:17202134) RGD PMID:17202134 MGI:5490819 NCBI chr17:61,331,669...61,334,285
Ensembl chr17:61,331,669...61,334,285
JBrowse link
G Sod1 superoxide dismutase 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:15473258)
UniProt
RGD
PMID:15473258 GO_REF:0000024 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    metabolic process 11797
      negative regulation of metabolic process 3180
        negative regulation of small molecule metabolic process 102
          negative regulation of cholesterol metabolic process 5
            negative regulation of cholesterol biosynthetic process 5
Path 2
Term Annotations click to browse term
  biological_process 19492
    biological regulation 13513
      regulation of biological process 12769
        regulation of metabolic process 6740
          regulation of primary metabolic process 5702
            regulation of lipid metabolic process 375
              regulation of steroid metabolic process 114
                regulation of steroid biosynthetic process 82
                  regulation of sterol biosynthetic process 22
                    regulation of cholesterol biosynthetic process 22
                      negative regulation of cholesterol biosynthetic process 5
paths to the root