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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of cholesterol biosynthetic process
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Accession:GO:0045541 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol.
Synonyms:exact_synonym: down regulation of cholesterol biosynthetic process;   downregulation of cholesterol biosynthetic process;   negative regulation of cholesterol anabolism;   negative regulation of cholesterol biosynthesis;   negative regulation of cholesterol formation;   negative regulation of cholesterol synthesis
 narrow_synonym: inhibition of cholesterol biosynthetic process


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negative regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in IDA
IEA
ISO		 GO_REF:0000107
(PMID:1917954)		 Ensembl
RGD		 PMID:1917954 PMID:9225228 GO_REF:0000107, RGD:10059686 NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Chlsn cholesin involved_in ISO (PMID:38503280) RGD PMID:38503280 NCBI chr12:15,185,728...15,289,042
Ensembl chr12:15,185,707...15,289,069 		JBrowse link
G Erlin1 ER lipid raft associated 1 involved_in ISO
IEA		 (PMID:24217618)
GO_REF:0000107		 RGD
Ensembl		 PMID:24217618 GO_REF:0000107 NCBI chr 1:252,870,356...252,905,681
Ensembl chr 1:242,921,152...242,956,394 		JBrowse link
G Erlin2 ER lipid raft associated 2 involved_in ISO (PMID:24217618) RGD PMID:24217618 NCBI chr16:71,720,486...71,736,999
Ensembl chr16:65,018,532...65,033,671 		JBrowse link
G Idi2 isopentenyl-diphosphate delta isomerase 2 acts_upstream_of_or_within ISO (PMID:17202134) RGD PMID:17202134 NCBI chr17:66,022,731...66,026,333
Ensembl chr17:61,331,669...61,334,285 		JBrowse link
G Insig1 insulin induced gene 1 involved_in ISO (PMID:26311497) RGD PMID:26311497 NCBI chr 4:8,049,339...8,057,812
Ensembl chr 4:7,315,495...7,323,952 		JBrowse link
G Mir185 microRNA 185 acts_upstream_of ISO RNAcentral:URS00002367FA_9606|RNAcentral:URS00004176D4_9606 (PMID:23951060), (PMID:24296663) RGD PMID:23951060 PMID:24296663 NCBI chr11:96,169,028...96,169,107
Ensembl chr11:82,664,716...82,664,795 		JBrowse link
G Mir342 microRNA 342 acts_upstream_of ISO (PMID:23951060) RGD PMID:23951060 NCBI chr 6:133,329,655...133,329,753
Ensembl chr 6:127,565,269...127,565,367 		JBrowse link
G Mir98 microRNA 98 involved_in ISO (PMID:30195495) RGD PMID:30195495 NCBI chr  X:24,460,648...24,460,755
Ensembl chr  X:20,981,235...20,981,342 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20567
    cellular process 19557
      metabolic process 12206
        negative regulation of metabolic process 3159
          negative regulation of small molecule metabolic process 140
            negative regulation of cholesterol metabolic process 12
              negative regulation of cholesterol biosynthetic process 9
Path 2
Term Annotations click to browse term
  biological_process 20567
    biological regulation 13841
      regulation of biological process 13403
        regulation of cellular process 13038
          regulation of metabolic process 6791
            regulation of primary metabolic process 5626
              regulation of lipid metabolic process 398
                regulation of steroid metabolic process 133
                  regulation of steroid biosynthetic process 103
                    regulation of sterol biosynthetic process 38
                      regulation of cholesterol biosynthetic process 38
                        negative regulation of cholesterol biosynthetic process 9
paths to the root