Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of cholesterol biosynthetic process
go back to main search page
Accession:GO:0045540 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol.
Synonyms:exact_synonym: regulation of cholesterol anabolism;   regulation of cholesterol biosynthesis;   regulation of cholesterol formation;   regulation of cholesterol synthesis



show annotations for term's descendants           Sort by:
 
regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP-binding cassette, sub-family A (ABC1), member 2 NOT|involved_in ISO (PMID:21810484) ARUK-UCL PMID:21810484 NCBI chr 2:25,428,599...25,448,544
Ensembl chr 2:25,428,703...25,448,540
JBrowse link
G Apob apolipoprotein B acts_upstream_of_or_within IMP (MGI:3652707|PMID:16455790) MGI PMID:16455790 MGI:3652707 NCBI chr12:7,977,629...8,016,839
Ensembl chr12:7,977,648...8,016,835
JBrowse link
G Dhcr7 7-dehydrocholesterol reductase involved_in ISO RGD
MGI
PMID:10329655 GO_REF:0000096 MGI:4417868 RGD:632010 NCBI chr 7:143,823,167...143,848,410
Ensembl chr 7:143,823,145...143,848,410
JBrowse link
G Lpcat3 lysophosphatidylcholine acyltransferase 3 involved_in IMP (MGI:6278041|PMID:29395055) UniProt PMID:29395055 MGI:6278041 NCBI chr 6:124,663,094...124,704,716
Ensembl chr 6:124,663,027...124,704,418
JBrowse link
G Pex2 peroxisomal biogenesis factor 2 acts_upstream_of_or_within IMP (MGI:3027293|PMID:14673138) MGI PMID:14673138 MGI:3027293 NCBI chr 3:5,560,188...5,578,596
Ensembl chr 3:5,560,188...5,576,239
JBrowse link
G Scap SREBF chaperone acts_upstream_of_or_within IMP (MGI:3770209|PMID:16054043) MGI PMID:16054043 MGI:3770209 NCBI chr 9:110,333,288...110,384,949
Ensembl chr 9:110,333,288...110,384,950
JBrowse link
negative regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in ISO MGI
RGD
PMID:9225228 GO_REF:0000096 MGI:4417868 MGI:4834177 RGD:10059686 NCBI chr 7:19,696,244...19,701,310
Ensembl chr 7:19,696,109...19,699,188
JBrowse link
G Erlin1 ER lipid raft associated 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr19:44,034,943...44,070,164
Ensembl chr19:44,034,944...44,069,785
JBrowse link
G Erlin2 ER lipid raft associated 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 8:27,023,371...27,039,437
Ensembl chr 8:27,023,261...27,040,328
JBrowse link
G Idi2 isopentenyl-diphosphate delta isomerase 2 acts_upstream_of_or_within IMP (MGI:5490819|PMID:17202134) MGI PMID:17202134 MGI:5490819 NCBI chr13:8,952,863...8,960,935
Ensembl chr13:8,952,863...8,960,945
JBrowse link
G Sod1 superoxide dismutase 1, soluble involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr16:90,220,762...90,226,333
Ensembl chr16:90,220,754...90,226,329
JBrowse link
positive regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg1 ATP binding cassette subfamily G member 1 involved_in IMP (MGI:3768186|PMID:17916878) BHF-UCL PMID:17916878 MGI:3768186 NCBI chr17:31,057,694...31,117,984
Ensembl chr17:31,057,675...31,117,988
JBrowse link
G Cyp7a1 cytochrome P450, family 7, subfamily a, polypeptide 1 involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 4:6,265,612...6,275,632
Ensembl chr 4:6,265,612...6,275,633
JBrowse link
G Fdps farnesyl diphosphate synthetase involved_in ISO RGD
MGI
PMID:18637708 GO_REF:0000096 MGI:4417868 RGD:2316295 NCBI chr 3:89,093,588...89,101,967
Ensembl chr 3:89,093,588...89,101,959
JBrowse link
G Fgf1 fibroblast growth factor 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr18:38,838,672...38,929,470
Ensembl chr18:38,838,673...38,929,472
JBrowse link
G Por cytochrome p450 oxidoreductase involved_in ISO RGD
MGI
PMID:19264869 GO_REF:0000096 MGI:4417868 RGD:2316785 NCBI chr 5:135,670,040...135,735,326
Ensembl chr 5:135,670,033...135,735,326
JBrowse link
G Scap SREBF chaperone involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 9:110,333,288...110,384,949
Ensembl chr 9:110,333,288...110,384,950
JBrowse link
G Scp2 sterol carrier protein 2, liver involved_in ISO RGD
MGI
PMID:2554812 GO_REF:0000096 MGI:4417868 RGD:9850260 NCBI chr 4:108,043,830...108,144,971
Ensembl chr 4:108,043,839...108,144,998
JBrowse link
G Sec14l2 SEC14-like lipid binding 2 involved_in ISO RGD
MGI
PMID:11226224 GO_REF:0000096 MGI:4417868 RGD:727312 NCBI chr11:4,097,039...4,118,729
Ensembl chr11:4,097,039...4,123,415
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 involved_in
acts_upstream_of_or_within
IDA
ISO
IMP
(MGI:3623165|PMID:9062341), (MGI:83216|PMID:8833906)
(MGI:3603730|PMID:16046411)
(MGI:1098057|PMID:9329978)
UniProt
MGI
PMID:8833906 PMID:9062341 PMID:9329978 PMID:16046411 GO_REF:0000096 MGI:1098057 MGI:3603730 MGI:3623165 MGI:4834177 MGI:83216 NCBI chr11:60,199,084...60,224,186
Ensembl chr11:60,199,089...60,222,581
JBrowse link
G Srebf2 sterol regulatory element binding factor 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr15:82,147,269...82,205,379
Ensembl chr15:82,147,181...82,205,379
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28616
    regulation of biological process 12619
      regulation of metabolic process 6890
        regulation of small molecule metabolic process 387
          regulation of alcohol biosynthetic process 52
            regulation of cholesterol biosynthetic process 20
              negative regulation of cholesterol biosynthetic process 5
              positive regulation of cholesterol biosynthetic process 10
Path 2
Term Annotations click to browse term
  biological_process 28616
    biological regulation 13269
      regulation of biological process 12619
        regulation of metabolic process 6890
          regulation of primary metabolic process 5744
            regulation of lipid metabolic process 391
              regulation of lipid biosynthetic process 207
                regulation of steroid biosynthetic process 86
                  regulation of sterol biosynthetic process 20
                    regulation of cholesterol biosynthetic process 20
                      negative regulation of cholesterol biosynthetic process 5
                      positive regulation of cholesterol biosynthetic process 10
paths to the root