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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of nitric oxide biosynthetic process
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Accession:GO:0045428 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide.
Synonyms:exact_synonym: regulation of nitric oxide anabolism;   regulation of nitric oxide biosynthesis;   regulation of nitric oxide formation;   regulation of nitric oxide synthesis

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regulation of nitric oxide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr2a activin A receptor type 2A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16093358) Ensembl
MGI		 PMID:16093358 GO_REF:0000107 NCBI chrNW_004936469:29,195,329...29,273,237
Ensembl chrNW_004936469:29,194,908...29,273,196 		JBrowse link
G Arg2 arginase 2 ISO RGD PMID:11829529 RGD:634667 NCBI chrNW_004936495:11,004,296...11,045,467
Ensembl chrNW_004936495:11,004,176...11,045,472 		JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936473:28,508,726...28,535,640
Ensembl chrNW_004936473:28,510,523...28,535,627 		JBrowse link
G Igf1 insulin like growth factor 1 acts_upstream_of_or_within ISO (PMID:21677284) MGI PMID:21677284 NCBI chrNW_004936492:11,709,623...11,784,028
Ensembl chrNW_004936492:11,709,222...11,778,351 		JBrowse link
G Jak2 Janus kinase 2 involved_in ISO PMID:16055727 ARUK-UCL PMID:16055727 RGD:13792550 NCBI chrNW_004936503:111,722...243,627
Ensembl chrNW_004936503:110,963...241,867 		JBrowse link
G LOC101967799 leukocyte surface antigen CD47 involved_in ISO (MGI:6201986|PMID:16055727) ARUK-UCL PMID:16055727 MGI:6201986 NCBI chrNW_004936645:1,363,406...1,408,624 JBrowse link
G Nosip nitric oxide synthase interacting protein involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936664:3,402,583...3,420,274
Ensembl chrNW_004936664:3,402,331...3,420,359 		JBrowse link
G Rac1 Rac family small GTPase 1 involved_in ISO PMID:16055727 ARUK-UCL PMID:16055727 RGD:13792550 NCBI chrNW_004936750:107,689...122,679
Ensembl chrNW_004936750:107,689...122,676 		JBrowse link
G Sirpa signal regulatory protein alpha involved_in ISO PMID:16055727 ARUK-UCL PMID:16055727 RGD:13792550 NCBI chrNW_004936485:16,608,317...16,654,552 JBrowse link
negative regulation of nitric oxide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp5 acid phosphatase 5, tartrate resistant involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11168643) Ensembl
MGI		 PMID:11168643 GO_REF:0000107 NCBI chrNW_004936659:1,598,252...1,642,615
Ensembl chrNW_004936659:1,598,177...1,600,262 		JBrowse link
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936567:944,825...1,039,920
Ensembl chrNW_004936567:950,797...993,245 		JBrowse link
G Cav1 caveolin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12388077) Ensembl
MGI		 PMID:12388077 GO_REF:0000107 NCBI chrNW_004936589:2,504,235...2,536,778
Ensembl chrNW_004936589:2,504,224...2,537,170 		JBrowse link
G Dynll1 dynein light chain LC8-type 1 acts_upstream_of_or_within
involved_in		 ISO PMID:8864115 MGI
UniProt		 PMID:8864115 RGD:633683 NCBI chrNW_004936668:451,846...484,841
Ensembl chrNW_004936668:448,489...500,800 		JBrowse link
G Epor erythropoietin receptor ISO RGD PMID:10489101 RGD:11041656 NCBI chrNW_004936659:1,468,391...1,473,880
Ensembl chrNW_004936659:1,468,634...1,473,880 		JBrowse link
G Gla galactosidase alpha involved_in ISO (MGI:3624267|PMID:15668341) UniProt PMID:15668341 MGI:3624267 NCBI chrNW_004936813:474,938...484,753
Ensembl chrNW_004936813:474,949...484,760 		JBrowse link
G Il10 interleukin 10 ISO RGD PMID:17017555 RGD:1598631 NCBI chrNW_004936557:5,834,874...5,838,502
Ensembl chrNW_004936557:5,834,874...5,838,502 		JBrowse link
G Khsrp KH-type splicing regulatory protein involved_in ISO (PMID:16126846) UniProt PMID:16126846 NCBI chrNW_004936588:3,764,401...3,774,492
Ensembl chrNW_004936588:3,766,332...3,773,872 		JBrowse link
G Oprm1 opioid receptor mu 1 involved_in ISO (PMID:20525224) UniProt PMID:20525224 NCBI chrNW_004936489:6,506,207...6,567,136
Ensembl chrNW_004936489:6,506,207...6,548,946 		JBrowse link
G Prl prolactin involved_in ISO (PMID:24530842) AgBase PMID:24530842 NCBI chrNW_004936552:7,204,298...7,212,632 JBrowse link
G Ptgis prostaglandin I2 synthase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936514:4,775,884...4,814,574
Ensembl chrNW_004936514:4,791,031...4,812,027 		JBrowse link
G Rgn regucalcin ISO RGD PMID:12686401 RGD:9590175 NCBI chrNW_004936502:12,872,938...12,891,270
Ensembl chrNW_004936502:12,872,824...12,891,506 		JBrowse link
G Rock2 Rho associated coiled-coil containing protein kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936532:7,142,580...7,284,722
Ensembl chrNW_004936532:7,145,882...7,286,244 		JBrowse link
G Sirpa signal regulatory protein alpha involved_in ISO (MGI:3760575|PMID:17954568) ARUK-UCL PMID:17954568 MGI:3760575 NCBI chrNW_004936485:16,608,317...16,654,552 JBrowse link
G Tspo translocator protein ISO RGD PMID:14678758 RGD:2317158 NCBI chrNW_004936718:992,301...995,172
Ensembl chrNW_004936718:992,301...995,995 		JBrowse link
G Wdr35 WD repeat domain 35 ISO RGD PMID:18671723 RGD:11553926 NCBI chrNW_004936493:11,374,681...11,435,792
Ensembl chrNW_004936493:11,374,671...11,436,233 		JBrowse link
G Zc3h12a zinc finger CCCH-type containing 12A involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936474:19,714,145...19,722,512
Ensembl chrNW_004936474:19,714,153...19,722,528 		JBrowse link
positive regulation of nitric oxide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen ISO RGD PMID:17616753 RGD:8548892 NCBI chrNW_004936484:19,713,299...19,721,144
Ensembl chrNW_004936484:19,716,165...19,721,261 		JBrowse link
G Agxt2 alanine--glyoxylate aminotransferase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936518:6,508,928...6,544,324
Ensembl chrNW_004936518:6,508,928...6,544,146 		JBrowse link
G Aif1 allograft inflammatory factor 1 ISO RGD PMID:16157606 RGD:2313017 NCBI chrNW_004936727:1,907,493...1,909,350
Ensembl chrNW_004936727:1,907,505...1,909,338 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936621:620,163...639,115
Ensembl chrNW_004936621:620,074...639,093 		JBrowse link
G Akt2 AKT serine/threonine kinase 2 ISO RGD PMID:18335029 RGD:2313325 NCBI chrNW_004936661:2,652,568...2,694,039
Ensembl chrNW_004936661:2,652,566...2,694,086 		JBrowse link
G Apoe apolipoprotein E involved_in ISO (PMID:8995232) BHF-UCL PMID:8995232 NCBI chrNW_004936706:1,512,438...1,516,805 JBrowse link
G App amyloid beta precursor protein involved_in ISO (PMID:20037584) ARUK-UCL PMID:20037584 NCBI chrNW_004936640:1,549,977...1,787,436
Ensembl chrNW_004936640:1,550,167...1,787,286 		JBrowse link
G Asl argininosuccinate lyase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936543:7,688,788...7,699,842
Ensembl chrNW_004936543:7,688,741...7,699,851 		JBrowse link
G Ass1 argininosuccinate synthase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936487:17,482,307...17,527,407
Ensembl chrNW_004936487:17,486,826...17,527,435 		JBrowse link
G Cd36 CD36 molecule (CD36 blood group) involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936810:791,823...838,303
Ensembl chrNW_004936810:758,182...838,365 		JBrowse link
G Clec7a C-type lectin domain containing 7A involved_in ISO (PMID:19358895) ARUK-UCL PMID:19358895 NCBI chrNW_004936902:436,224...446,435 JBrowse link
G Clu clusterin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936675:499,745...513,515
Ensembl chrNW_004936675:499,199...513,836 		JBrowse link
G Crp C-reactive protein ISO RGD PMID:9767445 RGD:9586000 NCBI chrNW_004936740:885,855...888,854
Ensembl chrNW_004936740:883,272...890,606 		JBrowse link
G Ddah1 dimethylarginine dimethylaminohydrolase 1 involved_in ISO
IEA		 RGD
TreeGrafter
Ensembl		 PMID:12237779 GO_REF:0000107 GO_REF:0000118 RGD:727432 NCBI chrNW_004936608:262,653...397,753
Ensembl chrNW_004936608:262,445...397,762 		JBrowse link
G Ddah2 DDAH family member 2, ADMA-independent involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936727:1,803,711...1,807,441
Ensembl chrNW_004936727:1,804,455...1,807,183 		JBrowse link
G Dnm2 dynamin 2 ISO RGD PMID:16973909 RGD:9685181 NCBI chrNW_004936659:957,408...1,046,393
Ensembl chrNW_004936659:957,392...1,049,188 		JBrowse link
G Esr1 estrogen receptor 1 involved_in ISO (PMID:21937726) UniProt PMID:21937726 NCBI chrNW_004936489:4,616,839...4,887,179
Ensembl chrNW_004936489:4,614,754...4,887,171 		JBrowse link
G Hrh1 histamine receptor H1 ISO RGD PMID:12419527 RGD:727463 NCBI chrNW_004936602:2,182,053...2,185,297
Ensembl chrNW_004936602:2,183,831...2,185,297 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 involved_in ISO (MGI:3687888|PMID:12855682) UniProt PMID:12855682 MGI:3687888 NCBI chrNW_004936835:316,767...321,999
Ensembl chrNW_004936835:316,767...321,990 		JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO RGD PMID:9062344 RGD:1600239 NCBI chrNW_004936659:616,570...627,172
Ensembl chrNW_004936659:616,752...627,174 		JBrowse link
G Ifng interferon gamma involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11168643) Ensembl
MGI		 PMID:11168643 GO_REF:0000107 NCBI chrNW_004936545:6,139,130...6,144,543
Ensembl chrNW_004936545:6,139,116...6,148,452 		JBrowse link
G Il1b interleukin 1 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936783:1,251,678...1,256,807
Ensembl chrNW_004936783:1,252,158...1,257,165 		JBrowse link
G Il6 interleukin 6 ISO RGD PMID:15845578 RGD:2306941 NCBI chrNW_004936549:7,015,595...7,016,246 JBrowse link
G Insr insulin receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936588:4,345,306...4,453,380
Ensembl chrNW_004936588:4,345,306...4,453,668 		JBrowse link
G Itgb2 integrin subunit beta 2 ISO RGD PMID:9062344 RGD:1600239 NCBI chrNW_004936778:1,286,475...1,311,184
Ensembl chrNW_004936778:1,286,341...1,311,194 		JBrowse link
G Jak2 Janus kinase 2 ISO RGD PMID:12595539 RGD:1641934 NCBI chrNW_004936503:111,722...243,627
Ensembl chrNW_004936503:110,963...241,867 		JBrowse link
G Klf4 KLF transcription factor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936559:5,105,456...5,109,970
Ensembl chrNW_004936559:5,105,463...5,109,970 		JBrowse link
G LOC101976242 NKG2-D type II integral membrane protein involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936902:216,495...229,150
Ensembl chrNW_004936902:216,495...229,141 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 ISO RGD PMID:10593906 RGD:2304240 NCBI chrNW_004936739:551,678...602,027
Ensembl chrNW_004936739:551,629...602,047 		JBrowse link
G Mtor mechanistic target of rapamycin kinase ISO RGD PMID:19576187 RGD:10041012 NCBI chrNW_004936474:158,376...282,310
Ensembl chrNW_004936474:157,590...282,342 		JBrowse link
G Nfatc3 nuclear factor of activated T cells 3 involved_in ISO (MGI:6871969|PMID:24970700) UniProt PMID:24970700 MGI:6871969 NCBI chrNW_004936475:18,462,424...18,557,832
Ensembl chrNW_004936475:18,462,298...18,555,220 		JBrowse link
G Oprm1 opioid receptor mu 1 involved_in ISO (PMID:20214800) UniProt PMID:20214800 NCBI chrNW_004936489:6,506,207...6,567,136
Ensembl chrNW_004936489:6,506,207...6,548,946 		JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18558630) Ensembl
BHF-UCL		 PMID:18558630 GO_REF:0000107 NCBI chrNW_004936540:907,118...1,041,814
Ensembl chrNW_004936540:907,112...1,041,848 		JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936905:76,781...128,995 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 involved_in ISO PMID:9630216 BHF-UCL PMID:9630216 RGD:5135054 NCBI chrNW_004936481:3,821,564...3,828,086 JBrowse link
G Ptk2b protein tyrosine kinase 2 beta ISO RGD PMID:21926342 RGD:10041069 NCBI chrNW_004936675:216,970...325,670
Ensembl chrNW_004936675:275,288...324,810 		JBrowse link
G Ptx3 pentraxin 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14726497) Ensembl
MGI		 PMID:14726497 GO_REF:0000107 NCBI chrNW_004936519:4,303,549...4,309,143
Ensembl chrNW_004936519:4,303,464...4,309,173 		JBrowse link
G Smad3 SMAD family member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936471:27,080,662...27,185,861
Ensembl chrNW_004936471:27,080,575...27,189,793 		JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 ISO RGD PMID:14720208 RGD:10042970 NCBI chrNW_004936475:18,667,563...18,755,132
Ensembl chrNW_004936475:18,671,428...18,755,208 		JBrowse link
G Sod2 superoxide dismutase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15637112) Ensembl
MGI		 PMID:15637112 GO_REF:0000107 NCBI chrNW_004936489:11,178,338...11,191,601
Ensembl chrNW_004936489:11,178,015...11,191,781 		JBrowse link
G Ticam1 toll like receptor adaptor molecule 1 acts_upstream_of_or_within ISO (PMID:12872135) MGI PMID:12872135 NCBI chrNW_004936588:2,818,909...2,827,797 JBrowse link
G Tlr2 toll like receptor 2 acts_upstream_of_or_within ISO (PMID:10549626), (PMID:16239543) MGI PMID:10549626 PMID:16239543 NCBI chrNW_004936576:522,234...531,660
Ensembl chrNW_004936576:527,434...529,788 		JBrowse link
G Tlr4 toll like receptor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10549626) Ensembl
MGI		 PMID:10549626 GO_REF:0000107 NCBI chrNW_004936487:6,519,140...6,532,018
Ensembl chrNW_004936487:6,518,441...6,533,095 		JBrowse link
G Tlr5 toll like receptor 5 ISO RGD PMID:16973131 RGD:1643119 NCBI chrNW_004936526:383,490...387,007
Ensembl chrNW_004936526:383,418...401,552 		JBrowse link
G Tlr6 toll like receptor 6 involved_in ISO (MGI:4438693|PMID:20037584) ARUK-UCL PMID:20037584 MGI:4438693 NCBI chrNW_004936482:6,607,723...6,610,161
Ensembl chrNW_004936482:6,607,753...6,610,143 		JBrowse link
G Tnf tumor necrosis factor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936727:1,936,066...1,937,766
Ensembl chrNW_004936727:1,936,066...1,937,766 		JBrowse link
G Trpv1 transient receptor potential cation channel subfamily V member 1 ISO RGD PMID:16081483 RGD:2317115 NCBI chrNW_004936677:277,304...326,907
Ensembl chrNW_004936677:276,994...327,025 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15969
    metabolic process 9630
      biosynthetic process 6737
        nitric oxide biosynthetic process 84
          regulation of nitric oxide biosynthetic process 70
            negative regulation of nitric oxide biosynthetic process 17
            positive regulation of nitric oxide biosynthetic process 47
Path 2
Term Annotations click to browse term
  biological_process 15969
    biological regulation 11154
      regulation of biological process 10818
        regulation of metabolic process 5604
          regulation of nitric oxide metabolic process 73
            regulation of nitric oxide biosynthetic process 70
              negative regulation of nitric oxide biosynthetic process 17
              positive regulation of nitric oxide biosynthetic process 47
paths to the root