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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of MHC class II biosynthetic process
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Accession:GO:0045347 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II.
Synonyms:exact_synonym: down regulation of MHC class II biosynthetic process;   downregulation of MHC class II biosynthetic process;   negative regulation of MHC class II anabolism;   negative regulation of MHC class II biosynthesis;   negative regulation of MHC class II formation;   negative regulation of MHC class II synthesis;   negative regulation of major histocompatibility complex class II biosynthesis;   negative regulation of major histocompatibility complex class II biosynthetic process
 narrow_synonym: inhibition of MHC class II biosynthetic process


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negative regulation of MHC class II biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il10 interleukin 10 involved_in ISO (PMID:1940799) RGD PMID:1940799 NCBI chr13:42,472,625...42,477,308 JBrowse link
G Marchf8 membrane associated ring-CH-type finger 8 involved_in ISO (MGI:3785681|PMID:16785530) RGD PMID:16785530 MGI:3785681 NCBI chr 4:149,415,642...149,530,771 JBrowse link
G Nfx1 nuclear transcription factor, X-box binding 1 acts_upstream_of_or_within ISO (MGI:2180954|PMID:12047746) RGD PMID:12047746 MGI:2180954 NCBI chr 5:56,104,945...56,162,912 JBrowse link
G Pf4 platelet factor 4 involved_in ISO (PMID:10666185) RGD PMID:10666185 NCBI chr14:17,298,438...17,299,148 JBrowse link
G Spi1 Spi-1 proto-oncogene involved_in ISO (MGI:4942273|PMID:7592651) RGD PMID:7592651 MGI:4942273 NCBI chr 3:77,059,744...77,093,730 JBrowse link
G Taf7 TATA-box binding protein associated factor 7 involved_in ISO (PMID:20937824) RGD PMID:20937824 NCBI chr18:29,459,937...29,462,086 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    negative regulation of biological process 5618
      negative regulation of metabolic process 3185
        negative regulation of biosynthetic process 1715
          negative regulation of macromolecule biosynthetic process 1611
            negative regulation of MHC class II biosynthetic process 6
Path 2
Term Annotations click to browse term
  biological_process 19492
    biological regulation 13513
      regulation of biological process 12769
        regulation of metabolic process 6740
          regulation of macromolecule metabolic process 6246
            regulation of macromolecule biosynthetic process 3835
              negative regulation of macromolecule biosynthetic process 1611
                negative regulation of MHC class II biosynthetic process 6
paths to the root