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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of MHC class II biosynthetic process
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Accession:GO:0045346 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II.
Synonyms:exact_synonym: regulation of MHC class II anabolism;   regulation of MHC class II biosynthesis;   regulation of MHC class II formation;   regulation of MHC class II synthesis;   regulation of major histocompatibility complex class II biosynthesis;   regulation of major histocompatibility complex class II biosynthetic process


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negative regulation of MHC class II biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il10 interleukin 10 involved_in ISO (PMID:1940799) RGD PMID:1940799 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Marchf8 membrane associated ring-CH-type finger 8 involved_in ISO (MGI:3785681|PMID:16785530) RGD PMID:16785530 MGI:3785681 NCBI chr 4:148,285,467...148,398,148
Ensembl chr 4:148,286,853...148,398,148
JBrowse link
G Nfx1 nuclear transcription factor, X-box binding 1 acts_upstream_of_or_within ISO (MGI:2180954|PMID:12047746) RGD PMID:12047746 MGI:2180954 NCBI chr 5:57,290,916...57,348,720
Ensembl chr 5:57,291,156...57,348,720
JBrowse link
G Pf4 platelet factor 4 involved_in ISO (PMID:10666185) RGD PMID:10666185 NCBI chr14:18,848,549...18,849,258
Ensembl chr14:18,848,549...18,849,258
JBrowse link
G Spi1 Spi-1 proto-oncogene involved_in ISO (MGI:4942273|PMID:7592651) RGD PMID:7592651 MGI:4942273 NCBI chr 3:79,918,127...79,937,708
Ensembl chr 3:79,918,969...79,938,301
JBrowse link
G Taf7 TATA-box binding protein associated factor 7 involved_in ISO (PMID:20937824) RGD PMID:20937824 NCBI chr18:30,779,149...30,781,297
Ensembl chr18:30,779,150...30,781,292
JBrowse link
positive regulation of MHC class II biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd40lg CD40 ligand IDA RGD PMID:18262271 RGD:2313421 NCBI chr  X:159,703,703...159,714,886
Ensembl chr  X:159,703,578...159,716,562
JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 involved_in ISO (PMID:29020624) RGD PMID:29020624 NCBI chr10:67,862,054...67,863,255
Ensembl chr10:67,862,054...67,863,255
JBrowse link
G Ciita class II, major histocompatibility complex, transactivator involved_in IEP
IBA
IDA
PMID:21873635 RGD
GO_Central
PMID:11477547, PMID:21873635, PMID:11071855 RGD:632487, RGD:13792537, RGD:632488 NCBI chr10:5,212,621...5,260,641
Ensembl chr10:5,213,350...5,260,608
JBrowse link
G Ifng interferon gamma involved_in
acts_upstream_of_or_within
IEP
ISO
UniProtKB:P05067|UniProtKB:P49768 (MGI:4942276|PMID:2502420), (MGI:4942277|PMID:2493384), (MGI:4943415|PMID:1845803), (MGI:5776417|PMID:26227742)
(MGI:3033882|PMID:11027433)
RGD PMID:1845803 PMID:2493384 PMID:2502420 PMID:11027433 PMID:26227742, PMID:3127329 MGI:3033882 MGI:4942276 MGI:4942277 MGI:4943415 MGI:5776417, RGD:8547557 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il10 interleukin 10 acts_upstream_of_or_within ISO (MGI:3033882|PMID:11027433) RGD PMID:11027433 MGI:3033882 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il33 interleukin 33 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:6414704|PMID:26936882)
Ensembl
RGD
PMID:26936882 GO_REF:0000107 MGI:6414704 NCBI chr 1:248,112,611...248,147,030
Ensembl chr 1:248,132,090...248,147,029
JBrowse link
G Il4 interleukin 4 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:2178646|PMID:10549626), (MGI:3033882|PMID:11027433)
RGD PMID:10549626 PMID:11027433, PMID:21873635 MGI:2178646 MGI:3033882, RGD:13792537 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Jak2 Janus kinase 2 involved_in ISO UniProtKB:P01580 (MGI:5776417|PMID:26227742) RGD PMID:26227742 MGI:5776417 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509
JBrowse link
G Sirt1 sirtuin 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:21890893)
Ensembl
RGD
PMID:21890893 GO_REF:0000107 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Tlr4 toll-like receptor 4 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1860885 (MGI:2178646|PMID:10549626)
Ensembl
RGD
PMID:10549626 GO_REF:0000107 MGI:2178646 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tmem106a transmembrane protein 106A involved_in ISS
ISO
GO_REF:0000024
(MGI:6216178|PMID:26215746)
UniProt
RGD
PMID:26215746 GO_REF:0000024 MGI:6216178 NCBI chr10:89,484,269...89,493,288
Ensembl chr10:89,484,468...89,493,283
JBrowse link
G Xbp1 X-box binding protein 1 involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:1903538)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:1903538 GO_REF:0000024 GO_REF:0000107 NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19610
    metabolic process 11878
      regulation of metabolic process 6774
        regulation of macromolecule metabolic process 6282
          regulation of macromolecule biosynthetic process 3824
            regulation of MHC class II biosynthetic process 17
              negative regulation of MHC class II biosynthetic process 6
              positive regulation of MHC class II biosynthetic process 12
Path 2
Term Annotations click to browse term
  biological_process 19610
    metabolic process 11878
      organic substance metabolic process 11408
        macromolecule metabolic process 9863
          macromolecule biosynthetic process 5102
            regulation of macromolecule biosynthetic process 3824
              regulation of MHC class II biosynthetic process 17
                negative regulation of MHC class II biosynthetic process 6
                positive regulation of MHC class II biosynthetic process 12
paths to the root