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ONTOLOGY REPORT - ANNOTATIONS


Term:farnesyl diphosphate metabolic process
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Accession:GO:0045338 term browser browse the term
Definition:The chemical reactions and pathways involving farnesyl diphosphate, an intermediate in carotenoid, sesquiterpene, squalene and sterol biosynthesis, as well as a substrate in protein farnesylation.
Synonyms:exact_synonym: farnesyl diphosphate metabolism


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farnesyl diphosphate metabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fdft1 farnesyl diphosphate farnesyl transferase 1 IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:16440058, PMID:21873635 RGD:1626611, RGD:13792537 NCBI chr15:46,339,248...46,367,302
Ensembl chr15:46,339,249...46,367,302
JBrowse link
farnesyl diphosphate biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fdps farnesyl diphosphate synthase IDA
IBA
IEA
PMID:21873635
GO_REF:0000041
UniProt PMID:8188698, PMID:21873635 GO_REF:0000041, RGD:2316305, RGD:13792537 NCBI chr 2:188,403,595...188,413,219
Ensembl chr 2:188,392,858...188,413,219
JBrowse link
G Ggps1 geranylgeranyl diphosphate synthase 1 IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr17:53,956,185...53,971,039
Ensembl chr17:53,956,203...53,971,443
JBrowse link
farnesyl diphosphate biosynthetic process, mevalonate pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase TAS RGD PMID:12841361 RGD:1300058 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:52,427,351...52,445,082
Ensembl chr 2:52,431,601...52,445,055
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:200,452,623...200,480,785
Ensembl chr 2:200,452,624...200,479,423
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20015
    cellular process 18788
      cellular metabolic process 11067
        cellular lipid metabolic process 1056
          phospholipid metabolic process 415
            farnesyl diphosphate metabolic process 6
              farnesyl diphosphate biosynthetic process + 5
              farnesyl diphosphate catabolic process 0
Path 2
Term Annotations click to browse term
  biological_process 20015
    metabolic process 12259
      primary metabolic process 10904
        lipid metabolic process 1378
          cellular lipid metabolic process 1056
            isoprenoid metabolic process 118
              terpenoid metabolic process 92
                farnesyl diphosphate metabolic process 6
                  farnesyl diphosphate biosynthetic process + 5
                  farnesyl diphosphate catabolic process 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.