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ONTOLOGY REPORT - ANNOTATIONS

Term:phospholipid translocation
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Accession:GO:0045332 term browser browse the term
Definition:The movement of a phospholipid molecule from one leaflet of a membrane bilayer to the opposite leaflet.
Comment:Note that this term describes the transbilayer motion of individual phospholipid molecules, and should not be confused with 'phospholipid scrambling ; GO:0017121'.
Synonyms:related_synonym: flippase;   phospholipid scrambling

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phospholipid translocation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:24097981)
(PMID:10878804)		 BHF-UCL
MGI		 PMID:10878804 PMID:24097981 NCBI chrNW_004955419:21,553,863...21,681,626
Ensembl chrNW_004955419:21,553,835...21,681,619 		JBrowse link
G Abca4 ATP binding cassette subfamily A member 4 involved_in ISO (PMID:24097981) BHF-UCL PMID:24097981 NCBI chrNW_004955423:612,098...738,702
Ensembl chrNW_004955423:612,098...736,035 		JBrowse link
G Abca7 ATP binding cassette subfamily A member 7 involved_in ISO (PMID:24097981) BHF-UCL PMID:24097981 NCBI chrNW_004955495:6,818,002...6,838,177
Ensembl chrNW_004955495:6,815,562...6,836,772 		JBrowse link
G Abcb1 ATP binding cassette subfamily B member 1 involved_in ISO (PMID:8898203)
(MGI:5795830|PMID:8898203)		 BHF-UCL PMID:8898203 MGI:5795830 NCBI chrNW_004955432:4,911,774...5,085,349 JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) involved_in ISO (PMID:17050692) BHF-UCL PMID:17050692 NCBI chrNW_004955442:729,322...858,826
Ensembl chrNW_004955442:729,316...860,290 		JBrowse link
G Ano6 anoctamin 6 involved_in ISO (MGI:6316485|PMID:30785399) UniProt PMID:30785399 MGI:6316485 NCBI chrNW_004955500:4,462,314...4,652,634
Ensembl chrNW_004955500:4,462,524...4,652,782 		JBrowse link
G Atp11c ATPase phospholipid transporting 11C involved_in ISO (MGI:5002406|PMID:21423173)
(PMID:32493773)		 UniProt
FlyBase		 PMID:21423173 PMID:32493773 MGI:5002406 NCBI chrNW_004955489:5,394,553...5,567,295
Ensembl chrNW_004955489:5,394,357...5,567,405 		JBrowse link
G Atp8b1 ATPase phospholipid transporting 8B1 involved_in ISO (PMID:20510206) UniProt PMID:20510206 NCBI chrNW_004955402:41,994,993...42,113,380
Ensembl chrNW_004955402:41,996,001...42,113,895 		JBrowse link
G Atp8b3 ATPase phospholipid transporting 8B3 acts_upstream_of_or_within ISO (PMID:14975727) MGI PMID:14975727 NCBI chrNW_004955495:6,222,764...6,242,104
Ensembl chrNW_004955495:6,222,602...6,242,569 		JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 acts_upstream_of_or_within ISO (PMID:18097031) MGI PMID:18097031 NCBI chrNW_004955555:1,493,600...1,509,113
Ensembl chrNW_004955555:1,490,052...1,509,113 		JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO (PMID:18097031) MGI PMID:18097031 NCBI chrNW_004955482:7,048,674...7,087,525
Ensembl chrNW_004955482:7,048,776...7,086,926 		JBrowse link
aminophospholipid translocation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp8a1 ATPase phospholipid transporting 8A1 involved_in ISO (PMID:31416931)
(MGI:6378348|PMID:20224745)		 UniProt
ARUK-UCL		 PMID:20224745 PMID:31416931 MGI:6378348 NCBI chrNW_004955443:5,142,049...5,362,031
Ensembl chrNW_004955443:5,142,049...5,362,147 		JBrowse link
calcium activated galactosylceramide scrambling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ano3 anoctamin 3 acts_upstream_of_or_within ISO (PMID:23532839) MGI PMID:23532839 NCBI chrNW_004955476:5,702,888...6,060,545
Ensembl chrNW_004955476:5,813,071...6,060,545 		JBrowse link
G Ano4 anoctamin 4 acts_upstream_of_or_within ISO (PMID:23532839) MGI PMID:23532839 NCBI chrNW_004955405:36,350,013...36,715,740
Ensembl chrNW_004955405:36,375,115...36,715,889 		JBrowse link
G Ano6 anoctamin 6 acts_upstream_of_or_within ISO (PMID:23532839) MGI PMID:23532839 NCBI chrNW_004955500:4,462,314...4,652,634
Ensembl chrNW_004955500:4,462,524...4,652,782 		JBrowse link
G Ano9 anoctamin 9 acts_upstream_of_or_within ISO (PMID:23532839) MGI PMID:23532839 NCBI chrNW_004955476:11,588,043...11,603,027
Ensembl chrNW_004955476:11,589,097...11,602,532 		JBrowse link
calcium activated phosphatidylcholine scrambling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ano3 anoctamin 3 acts_upstream_of_or_within ISO (PMID:23532839) MGI PMID:23532839 NCBI chrNW_004955476:5,702,888...6,060,545
Ensembl chrNW_004955476:5,813,071...6,060,545 		JBrowse link
G Ano4 anoctamin 4 acts_upstream_of_or_within ISO (PMID:23532839) MGI PMID:23532839 NCBI chrNW_004955405:36,350,013...36,715,740
Ensembl chrNW_004955405:36,375,115...36,715,889 		JBrowse link
G Ano6 anoctamin 6 acts_upstream_of_or_within ISO (PMID:23532839) MGI PMID:23532839 NCBI chrNW_004955500:4,462,314...4,652,634
Ensembl chrNW_004955500:4,462,524...4,652,782 		JBrowse link
G Ano9 anoctamin 9 acts_upstream_of_or_within ISO (PMID:23532839) MGI PMID:23532839 NCBI chrNW_004955476:11,588,043...11,603,027
Ensembl chrNW_004955476:11,589,097...11,602,532 		JBrowse link
calcium activated phosphatidylserine scrambling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ano4 anoctamin 4 acts_upstream_of_or_within ISO (PMID:23532839) MGI PMID:23532839 NCBI chrNW_004955405:36,350,013...36,715,740
Ensembl chrNW_004955405:36,375,115...36,715,889 		JBrowse link
G Ano6 anoctamin 6 acts_upstream_of_or_within ISO (PMID:23532839) MGI PMID:23532839 NCBI chrNW_004955500:4,462,314...4,652,634
Ensembl chrNW_004955500:4,462,524...4,652,782 		JBrowse link
G Ano9 anoctamin 9 acts_upstream_of_or_within ISO (PMID:23532839) MGI PMID:23532839 NCBI chrNW_004955476:11,588,043...11,603,027
Ensembl chrNW_004955476:11,589,097...11,602,532 		JBrowse link
calcium activated phospholipid scrambling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ano6 anoctamin 6 acts_upstream_of_or_within ISO (PMID:22936354)
(PMID:23532839)		 MGI PMID:22936354 PMID:23532839 NCBI chrNW_004955500:4,462,314...4,652,634
Ensembl chrNW_004955500:4,462,524...4,652,782 		JBrowse link
lysophospholipid translocation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mfsd2a MFSD2 lysolipid transporter A, lysophospholipid involved_in ISO (PMID:26005865) ARUK-UCL PMID:26005865 NCBI chrNW_004955452:17,430,850...17,443,830
Ensembl chrNW_004955452:17,430,219...17,443,830 		JBrowse link
phosphatidylserine exposure on apoptotic cell surface term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ano6 anoctamin 6 NOT|acts_upstream_of_or_within ISO (PMID:22936354)
(PMID:23532839)		 MGI PMID:22936354 PMID:23532839 NCBI chrNW_004955500:4,462,314...4,652,634
Ensembl chrNW_004955500:4,462,524...4,652,782 		JBrowse link
G Plscr1 phospholipid scramblase 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:32110987)
(PMID:12509439)
(MGI:6450314|PMID:32110987)		 UniProt
MGI		 PMID:12509439 PMID:32110987 MGI:6450314 NCBI chrNW_004955474:10,953,381...10,989,100 JBrowse link
G Trpc5 transient receptor potential cation channel subfamily C member 5 involved_in ISO (MGI:6450314|PMID:32110987) UniProt PMID:32110987 MGI:6450314 NCBI chrNW_004955490:3,777,756...4,057,275
Ensembl chrNW_004955490:3,860,909...4,057,275 		JBrowse link
G Xkr4 XK related 4 involved_in ISO (PMID:33725486)
(MGI:6706096|PMID:33725486), (MGI:6716960|PMID:25231987)		 UniProt PMID:25231987 PMID:33725486 MGI:6706096 MGI:6716960 NCBI chrNW_004955454:14,311,466...14,704,334
Ensembl chrNW_004955454:14,313,308...14,687,687 		JBrowse link
G Xkr8 XK related 8 involved_in
acts_upstream_of_or_within		 ISO (PMID:23845944)
(PMID:29440417)
(MGI:6716960|PMID:25231987), (MGI:6716970|PMID:30718401)
(MGI:5502792|PMID:23845944), (MGI:6435898|PMID:31712393)		 UniProt
MGI		 PMID:23845944 PMID:25231987 PMID:29440417 PMID:30718401 PMID:31712393 MGI:5502792 MGI:6435898 MGI:6716960 MGI:6716970 NCBI chrNW_004955452:7,141,088...7,148,571
Ensembl chrNW_004955452:7,141,201...7,146,443 		JBrowse link
G Xkr9 XK related 9 involved_in ISO (MGI:6716960|PMID:25231987) UniProt PMID:25231987 MGI:6716960 NCBI chrNW_004955444:9,027,662...9,059,911
Ensembl chrNW_004955444:9,025,635...9,053,775 		JBrowse link
phosphatidylserine exposure on blood platelet term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ano6 anoctamin 6 involved_in ISO (PMID:21107324) UniProt PMID:21107324 NCBI chrNW_004955500:4,462,314...4,652,634
Ensembl chrNW_004955500:4,462,524...4,652,782 		JBrowse link
plasma membrane phospholipid scrambling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ano3 anoctamin 3 acts_upstream_of_or_within ISO (MGI:5496475|PMID:23532839) GOC PMID:23532839 MGI:5496475 NCBI chrNW_004955476:5,702,888...6,060,545
Ensembl chrNW_004955476:5,813,071...6,060,545 		JBrowse link
G Ano4 anoctamin 4 acts_upstream_of_or_within ISO (MGI:5496475|PMID:23532839) GOC PMID:23532839 MGI:5496475 NCBI chrNW_004955405:36,350,013...36,715,740
Ensembl chrNW_004955405:36,375,115...36,715,889 		JBrowse link
G Ano6 anoctamin 6 involved_in ISO (PMID:25651887), (PMID:30700552)
(MGI:5440105|PMID:23021219)		 UniProt PMID:23021219 PMID:25651887 PMID:30700552 MGI:5440105 NCBI chrNW_004955500:4,462,314...4,652,634
Ensembl chrNW_004955500:4,462,524...4,652,782 		JBrowse link
G Ano9 anoctamin 9 acts_upstream_of_or_within ISO (MGI:5496475|PMID:23532839) GOC PMID:23532839 MGI:5496475 NCBI chrNW_004955476:11,588,043...11,603,027
Ensembl chrNW_004955476:11,589,097...11,602,532 		JBrowse link
G P2rx7 purinergic receptor P2X 7 involved_in ISO (PMID:25651887) UniProt PMID:25651887 NCBI chrNW_004955482:7,048,674...7,087,525
Ensembl chrNW_004955482:7,048,776...7,086,926 		JBrowse link
G Plscr1 phospholipid scramblase 1 involved_in ISO PMID:17712045
(MGI:5284813|PMID:12509439)
(PMID:10770950), (PMID:18629440), (PMID:9218461)		 UniProt PMID:9218461 PMID:10770950 PMID:12509439 PMID:17712045 PMID:18629440 MGI:5284813 RGD:8553758 NCBI chrNW_004955474:10,953,381...10,989,100 JBrowse link
G Slc4a1 solute carrier family 4 member 1 (Diego blood group) acts_upstream_of_or_within ISO (PMID:9716609) MGI PMID:9716609 NCBI chrNW_004955451:17,318,600...17,330,943
Ensembl chrNW_004955451:17,315,024...17,328,103 		JBrowse link
positive regulation of phosphatidylserine exposure on apoptotic cell surface term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Faslg Fas ligand involved_in ISO (PMID:24904167) UniProt PMID:24904167 NCBI chrNW_004955406:13,098,479...13,107,045
Ensembl chrNW_004955406:13,098,662...13,107,389 		JBrowse link
G Xrcc4 X-ray repair cross complementing 4 involved_in ISO (PMID:33725486) UniProt PMID:33725486 NCBI chrNW_004955418:27,174,510...27,426,245
Ensembl chrNW_004955418:27,173,659...27,426,264 		JBrowse link
positive regulation of phospholipid translocation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp8a1 ATPase phospholipid transporting 8A1 involved_in ISO (MGI:5302172|PMID:22007859) UniProt PMID:22007859 MGI:5302172 NCBI chrNW_004955443:5,142,049...5,362,031
Ensembl chrNW_004955443:5,142,049...5,362,147 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12321
    biological regulation 8863
      regulation of biological quality 2618
        regulation of membrane lipid distribution 31
          lipid translocation 25
            phospholipid translocation 24
              aminophospholipid translocation 1
              lysophospholipid translocation 1
              negative regulation of phospholipid translocation + 0
              plasma membrane phospholipid scrambling + 13
              positive regulation of phospholipid translocation + 3
              regulation of phospholipid translocation + 3
Path 2
Term Annotations click to browse term
  biological_process 12321
    localization 4252
      establishment of localization 3589
        transport 3317
          organic substance transport 1657
            lipid transport 304
              lipid translocation 25
                phospholipid translocation 24
                  aminophospholipid translocation 1
                  lysophospholipid translocation 1
                  negative regulation of phospholipid translocation + 0
                  plasma membrane phospholipid scrambling + 13
                  positive regulation of phospholipid translocation + 3
                  regulation of phospholipid translocation + 3
paths to the root