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ONTOLOGY REPORT - ANNOTATIONS


Term:oxoglutarate dehydrogenase complex
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Accession:GO:0045252 term browser browse the term
Definition:A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2).
Comment:See also the molecular functions term 'oxoglutarate dehydrogenase (succinyl-transferring) activity ; GO:0004591', 'dihydrolipoyllysine-residue succinyltransferase activity ; GO:0004149' and 'dihydrolipoyl dehydrogenase activity ; GO:0004148'.
Synonyms:exact_synonym: dihydrolipoamide S-succinyltransferase complex


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oxoglutarate dehydrogenase complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dld dihydrolipoamide dehydrogenase part_of IDA
ISO
IBA
(PMID:29211711)
PMID:21873635
RGD PMID:29211711, PMID:3571202, PMID:21873635 RGD:2306876, RGD:13792537 NCBI chr 6:50,597,677...50,618,694
Ensembl chr 6:50,597,677...50,618,694
JBrowse link
G Dlst dihydrolipoamide S-succinyltransferase part_of IDA
IEA
ISO
GO_REF:0000107
(PMID:29211711)
Ensembl
RGD
PMID:29211711, PMID:9405249, PMID:3571202 GO_REF:0000107, RGD:1359804, RGD:2306876 NCBI chr 6:108,936,534...108,961,322
Ensembl chr 6:108,936,664...108,959,803
JBrowse link
G Kat2a lysine acetyltransferase 2A colocalizes_with ISO (PMID:29211711) RGD PMID:29211711 NCBI chr10:88,611,586...88,619,558
Ensembl chr10:88,611,586...88,619,537
JBrowse link
G Ogdh oxoglutarate dehydrogenase part_of IDA
IBA
ISO
PMID:21873635
(PMID:29211711)
RGD PMID:29211711, PMID:3571202, PMID:21873635 RGD:2306876, RGD:13792537 NCBI chr14:86,414,924...86,481,903
Ensembl chr14:86,414,949...86,613,327
JBrowse link
G Ogdhl oxoglutarate dehydrogenase L part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:8,497,495...8,523,552
Ensembl chr16:8,497,569...8,523,557
JBrowse link
mitochondrial oxoglutarate dehydrogenase complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mrps36 mitochondrial ribosomal protein S36 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:30,740,620...30,750,916
Ensembl chr 2:30,739,855...30,748,428
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20142
    protein-containing complex 6031
      tricarboxylic acid cycle enzyme complex 16
        dihydrolipoyl dehydrogenase complex 9
          oxoglutarate dehydrogenase complex 6
            cytosolic oxoglutarate dehydrogenase complex 0
            mitochondrial oxoglutarate dehydrogenase complex 1
Path 2
Term Annotations click to browse term
  cellular_component 20142
    cellular anatomical entity 19842
      intracellular anatomical structure 14431
        cytoplasm 11416
          tricarboxylic acid cycle enzyme complex 16
            dihydrolipoyl dehydrogenase complex 9
              oxoglutarate dehydrogenase complex 6
                cytosolic oxoglutarate dehydrogenase complex 0
                mitochondrial oxoglutarate dehydrogenase complex 1
paths to the root