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ONTOLOGY REPORT - ANNOTATIONS


Term:cytosolic oxoglutarate dehydrogenase complex
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Accession:GO:0045248 term browser browse the term
Definition:A cytosolic complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2).
Comment:See also the molecular functions term 'oxoglutarate dehydrogenase (succinyl-transferring) activity ; GO:0004591', 'dihydrolipoyllysine-residue succinyltransferase activity ; GO:0004149' and 'dihydrolipoyl dehydrogenase activity ; GO:0004148'.
Synonyms:only_in_taxon: NCBITaxon:2 ! Bacteria;   NCBITaxon:2157 ! Archaea


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  cellular_component 20126
    cellular anatomical entity 19825
      cytosol 4232
        cytosolic oxoglutarate dehydrogenase complex 0
Path 2
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  cellular_component 20126
    cellular anatomical entity 19825
      intracellular anatomical structure 14390
        cytoplasm 11380
          tricarboxylic acid cycle enzyme complex 16
            dihydrolipoyl dehydrogenase complex 9
              oxoglutarate dehydrogenase complex 6
                cytosolic oxoglutarate dehydrogenase complex 0
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