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ONTOLOGY REPORT - ANNOTATIONS


Term:tricarboxylic acid cycle enzyme complex
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Accession:GO:0045239 term browser browse the term
Definition:Any of the heteromeric enzymes that act in the TCA cycle.
Synonyms:exact_synonym: TCA cycle enzyme complex


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tricarboxylic acid cycle enzyme complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fh fumarate hydratase IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr13:93,651,486...93,677,371
Ensembl chr13:93,651,484...93,677,377
JBrowse link
mitochondrial alpha-ketoglutarate dehydrogenase complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bckdha branched chain keto acid dehydrogenase E1 subunit alpha ISO
IBA
ISS
(PMID:7883996)
PMID:21873635
GO_REF:0000024
RGD
HGNC
PMID:7883996, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 1:82,423,291...82,452,094
Ensembl chr 1:82,423,277...82,452,281
JBrowse link
G Bckdhb branched chain keto acid dehydrogenase E1 subunit beta ISO
IBA
ISS
IEA
(PMID:2022752)
PMID:21873635
GO_REF:0000024
GO_REF:0000107
RGD
HGNC
Ensembl
PMID:2022752, PMID:21873635 GO_REF:0000024, GO_REF:0000107, RGD:13792537 NCBI chr 8:91,464,229...91,656,134
Ensembl chr 8:91,464,229...91,656,134
JBrowse link
G Bckdk branched chain ketoacid dehydrogenase kinase IDA PMID:1377677 HGNC PMID:1377677 RGD:68712 NCBI chr 1:199,351,628...199,356,299
Ensembl chr 1:199,351,628...199,356,881
JBrowse link
mitochondrial isocitrate dehydrogenase complex (NAD+) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Idh3a isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha IC RGD PMID:938457 RGD:2306828 NCBI chr 8:59,164,601...59,183,899
Ensembl chr 8:59,164,572...59,183,908
JBrowse link
G Idh3b isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta IC RGD PMID:938457 RGD:2306828 NCBI chr 3:122,808,564...122,813,638
Ensembl chr 3:122,808,564...122,813,583
JBrowse link
G Idh3g isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma IC RGD PMID:938457 RGD:2306828 NCBI chr  X:156,999,803...157,008,735
Ensembl chr  X:156,999,826...157,008,733
JBrowse link
mitochondrial oxoglutarate dehydrogenase complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mrps36 mitochondrial ribosomal protein S36 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:30,740,620...30,750,916
Ensembl chr 2:30,739,855...30,748,428
JBrowse link
oxoglutarate dehydrogenase complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dld dihydrolipoamide dehydrogenase IDA
IBA
ISO
PMID:21873635
(PMID:29211711)
RGD PMID:29211711, PMID:3571202, PMID:21873635 RGD:2306876, RGD:13792537 NCBI chr 6:50,597,677...50,618,694
Ensembl chr 6:50,597,677...50,618,694
JBrowse link
G Dlst dihydrolipoamide S-succinyltransferase IDA
ISO
IEA
(PMID:29211711)
GO_REF:0000107
RGD
Ensembl
PMID:29211711, PMID:9405249, PMID:3571202 GO_REF:0000107, RGD:1359804, RGD:2306876 NCBI chr 6:108,936,534...108,961,322
Ensembl chr 6:108,936,664...108,959,803
JBrowse link
G Kat2a lysine acetyltransferase 2A colocalizes_with ISO (PMID:29211711) RGD PMID:29211711 NCBI chr10:88,611,586...88,619,558
Ensembl chr10:88,611,586...88,619,537
JBrowse link
G LOC103693780 2-oxoglutarate dehydrogenase, mitochondrial-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:86,599,906...86,614,963
Ensembl chr14:86,414,949...86,613,327
JBrowse link
G Ogdh oxoglutarate dehydrogenase IDA
IBA
ISO
PMID:21873635
(PMID:29211711)
RGD PMID:29211711, PMID:3571202, PMID:21873635 RGD:2306876, RGD:13792537 NCBI chr14:86,414,924...86,481,903
Ensembl chr14:86,414,949...86,613,327
JBrowse link
G Ogdhl oxoglutarate dehydrogenase L IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:8,497,495...8,523,552
Ensembl chr16:8,497,569...8,523,557
JBrowse link
succinate-CoA ligase complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sucla2 succinate-CoA ligase ADP-forming subunit beta IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:55,461,695...55,516,954
Ensembl chr15:55,461,695...55,516,952
JBrowse link
G Suclg2 succinate-CoA ligase GDP-forming subunit beta IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:127,552,100...127,824,970
Ensembl chr 4:127,552,101...127,824,970
JBrowse link
succinate-CoA ligase complex (ADP-forming) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Suclg1 succinate-CoA ligase GDP/ADP-forming subunit alpha IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:101,181,315...101,210,692
Ensembl chr 4:101,180,404...101,210,746
JBrowse link
succinate-CoA ligase complex (GDP-forming) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Suclg1 succinate-CoA ligase GDP/ADP-forming subunit alpha IDA RGD PMID:7430155 RGD:2306879 NCBI chr 4:101,181,315...101,210,692
Ensembl chr 4:101,180,404...101,210,746
JBrowse link
G Suclg2 succinate-CoA ligase GDP-forming subunit beta IDA RGD PMID:7430155 RGD:2306879 NCBI chr 4:127,552,100...127,824,970
Ensembl chr 4:127,552,101...127,824,970
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20609
    protein-containing complex 6093
      tricarboxylic acid cycle enzyme complex 17
        cytosolic tricarboxylic acid cycle enzyme complex + 0
        dihydrolipoyl dehydrogenase complex + 10
        isocitrate dehydrogenase complex (NAD+) + 3
        mitochondrial tricarboxylic acid cycle enzyme complex + 9
        succinate-CoA ligase complex + 3
Path 2
Term Annotations click to browse term
  cellular_component 20609
    cellular anatomical entity 20358
      intracellular anatomical structure 14706
        cytoplasm 11456
          tricarboxylic acid cycle enzyme complex 17
            cytosolic tricarboxylic acid cycle enzyme complex + 0
            dihydrolipoyl dehydrogenase complex + 10
            isocitrate dehydrogenase complex (NAD+) + 3
            mitochondrial tricarboxylic acid cycle enzyme complex + 9
            succinate-CoA ligase complex + 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.