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ONTOLOGY REPORT - ANNOTATIONS

Term:sarcomere organization
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Accession:GO:0045214 term browser browse the term
Definition:The myofibril assembly process that results in the organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
Synonyms:exact_synonym: sarcomere alignment;   sarcomere organisation
 alt_id: GO:0006938


show annotations for term's descendants           Sort by:
sarcomere organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actg1 actin, gamma 1 acts_upstream_of_or_within ISO (PMID:15194427) RGD PMID:15194427 NCBI chr10:106,118,106...106,120,951
Ensembl chr10:105,619,737...105,624,232
Ensembl chr 3:105,619,737...105,624,232 		JBrowse link
G Actn1 actinin, alpha 1 involved_in ISS GO_REF:0000024 AgBase GO_REF:0000024 NCBI chr 6:98,998,553...99,093,334
Ensembl chr 6:98,998,556...99,093,251 		JBrowse link
G Actn2 actinin alpha 2 involved_in ISO
IEA 		(PMID:25433700)
GO_REF:0000107 		RGD
Ensembl		 PMID:25433700 GO_REF:0000107 NCBI chr17:62,835,055...62,902,331
Ensembl chr17:58,142,625...58,210,622 		JBrowse link
G Bmp10 bone morphogenetic protein 10 involved_in IMP PMID:17921333 BHF-UCL PMID:17921333 RGD:2302083 NCBI chr 4:119,872,066...119,877,694
Ensembl chr 4:119,872,045...119,878,627 		JBrowse link
G Capn3 calpain 3 involved_in
acts_upstream_of_or_within 		ISS
ISO
IEA 		GO_REF:0000024
MGI:3046866 (PMID:15138196)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:15138196 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:107,407,518...107,457,858
Ensembl chr 3:107,407,850...107,457,858 		JBrowse link
G Casq1 calsequestrin 1 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:22049211) 		UniProt
Ensembl
RGD		 PMID:22049211 GO_REF:0000024 GO_REF:0000107 NCBI chr13:84,670,648...84,680,339
Ensembl chr13:84,670,649...84,680,339 		JBrowse link
G Casq2 calsequestrin 2 involved_in ISO (PMID:19920148) RGD PMID:19920148 NCBI chr 2:189,526,003...189,582,276
Ensembl chr 2:189,525,960...189,582,267 		JBrowse link
G Cfl2 cofilin 2 acts_upstream_of_or_within ISO
IEA 		MGI:2182095|MGI:5316051|MGI:5316057 (PMID:22343409)
GO_REF:0000107 		RGD
Ensembl		 PMID:22343409 GO_REF:0000107 NCBI chr 6:78,090,843...78,094,888
Ensembl chr 6:72,355,664...72,359,674 		JBrowse link
G Csrp1 cysteine and glycine-rich protein 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:47,158,171...47,179,388
Ensembl chr13:47,167,789...47,179,384 		JBrowse link
G Csrp2 cysteine and glycine-rich protein 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:46,349,109...46,367,743
Ensembl chr 7:46,348,686...46,367,745 		JBrowse link
G Csrp3 cysteine and glycine rich protein 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:98,528,067...98,546,647
Ensembl chr 1:98,528,068...98,546,653 		JBrowse link
G ENSRNOG00000066401 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr13:38,581,746...38,582,497 JBrowse link
G ENSRNOG00000066789 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr20:29,411,228...29,412,019 JBrowse link
G Fhod3 formin homology 2 domain containing 3 acts_upstream_of_or_within
involved_in 		IMP
ISO
IBA 		PMID:19706596
UniProtKB:F1LQJ2 (PMID:19706596)
GO_REF:0000033 		RGD
GO_Central		 PMID:19706596 PMID:19706596 GO_REF:0000033, RGD:8554207 NCBI chr18:15,993,079...16,425,796
Ensembl chr18:15,993,324...16,425,796 		JBrowse link
G Flii FLII, actin remodeling protein involved_in ISO
IEA 		(PMID:37126682)
GO_REF:0000107 		RGD
Ensembl		 PMID:37126682 GO_REF:0000107 NCBI chr10:45,394,032...45,408,051
Ensembl chr10:45,394,032...45,407,970 		JBrowse link
G Flnc filamin C involved_in ISO
IEA
ISS 		(PMID:34405687)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:34405687 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:58,999,445...59,027,240
Ensembl chr 4:58,034,189...58,061,844 		JBrowse link
G Itgb1 integrin subunit beta 1 acts_upstream_of_or_within ISO MGI:2154539 (PMID:9004034) RGD PMID:9004034 NCBI chr19:73,602,277...73,650,271
Ensembl chr19:56,705,171...56,753,195 		JBrowse link
G Krt19 keratin 19 involved_in ISO
IEA 		(PMID:16000376)
GO_REF:0000107 		RGD
Ensembl		 PMID:16000376 GO_REF:0000107 NCBI chr10:85,075,835...85,080,552
Ensembl chr10:85,066,802...85,171,799 		JBrowse link
G Krt8 keratin 8 involved_in IDA PMID:15247274 UniProt PMID:15247274 RGD:1600063 NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728 		JBrowse link
G Ldb3 LIM domain binding 3 acts_upstream_of_or_within ISO
IEA 		MGI:2652058 (PMID:11696561)
GO_REF:0000107 		RGD
Ensembl		 PMID:11696561 GO_REF:0000107 NCBI chr16:9,855,768...9,920,108
Ensembl chr16:9,855,927...9,918,532 		JBrowse link
G Lmod2 leiomodin 2 involved_in ISO
IEA
IMP 		(PMID:18403713)
(PMID:27274810)
GO_REF:0000107 		RGD
Ensembl		 PMID:18403713 PMID:27274810 PMID:18403713 GO_REF:0000107, RGD:11344939 NCBI chr 4:53,067,428...53,075,124
Ensembl chr 4:53,067,428...53,075,120 		JBrowse link
G Mybpc1 myosin binding protein C1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:24,817,770...24,903,681
Ensembl chr 7:22,930,350...23,015,957 		JBrowse link
G Mybpc2 myosin binding protein C2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:94,994,121...95,017,584
Ensembl chr 1:94,994,104...95,017,584 		JBrowse link
G Mybpc3 myosin binding protein C3 involved_in
acts_upstream_of_or_within 		IBA
ISO 		GO_REF:0000033
MGI:2654420|MGI:3606208 (PMID:16224063), (PMID:16380103), (PMID:17075052) 		GO_Central
RGD		 PMID:16224063 PMID:16380103 PMID:17075052 GO_REF:0000033 NCBI chr 3:77,095,165...77,113,406
Ensembl chr 3:77,095,252...77,113,405 		JBrowse link
G Mybph myosin binding protein H involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:45,653,156...45,660,893
Ensembl chr13:45,653,234...45,660,893 		JBrowse link
G Myh6 myosin heavy chain 6 acts_upstream_of_or_within ISO
IEA 		MGI:3652543 (PMID:8878443)
GO_REF:0000107 		RGD
Ensembl		 PMID:8878443 GO_REF:0000107 NCBI chr15:28,418,120...28,442,316
Ensembl chr15:28,417,616...28,441,720 		JBrowse link
G Mylk3 myosin light chain kinase 3 involved_in IMP
IEA
IBA
ISO 		PMID:18202317
GO_REF:0000107
GO_REF:0000033
(PMID:18202317) 		Ensembl
GO_Central
RGD		 PMID:18202317 PMID:18202317 GO_REF:0000033 GO_REF:0000107, RGD:8554765 NCBI chr19:37,858,298...37,916,805
Ensembl chr19:21,691,929...21,742,954 		JBrowse link
G Myom1 myomesin 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:110,916,156...111,039,344
Ensembl chr 9:110,915,943...111,039,344 		JBrowse link
G Myom2 myomesin 2 involved_in ISO
IEA
IBA 		(PMID:33033063)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:33033063 GO_REF:0000033 GO_REF:0000107 NCBI chr16:74,520,148...74,592,658
Ensembl chr16:74,520,157...74,592,772 		JBrowse link
G Myom3 myomesin 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:153,276,306...153,326,847
Ensembl chr 5:147,992,737...148,043,274 		JBrowse link
G Myoz1 myozenin 1 involved_in ISO
IEA 		(PMID:18846255)
GO_REF:0000107 		RGD
Ensembl		 PMID:18846255 GO_REF:0000107 NCBI chr15:3,644,333...3,651,584
Ensembl chr15:3,644,368...3,652,884 		JBrowse link
G Myoz2 myozenin 2 involved_in ISO
IEA 		(PMID:15543153)
GO_REF:0000107 		RGD
Ensembl		 PMID:15543153 GO_REF:0000107 NCBI chr 2:211,141,463...211,168,187
Ensembl chr 2:211,141,463...211,168,221 		JBrowse link
G Mypn myopalladin involved_in ISO
IEA 		(PMID:11309420)
GO_REF:0000107 		RGD
Ensembl		 PMID:11309420 GO_REF:0000107 NCBI chr20:25,429,898...25,522,443
Ensembl chr20:25,436,843...25,522,443 		JBrowse link
G Neurl2 neuralized E3 ubiquitin protein ligase 2 acts_upstream_of_or_within ISO MGI:3043523 (PMID:14960280) RGD PMID:14960280 NCBI chr 3:153,566,659...153,569,380
Ensembl chr 3:153,566,660...153,569,380 		JBrowse link
G Plec plectin involved_in ISO
IEA 		(PMID:24487589)
GO_REF:0000107 		RGD
Ensembl		 PMID:24487589 GO_REF:0000107 NCBI chr 7:109,768,447...109,829,798
Ensembl chr 7:107,887,764...107,945,467 		JBrowse link
G Prkar1a protein kinase cAMP-dependent type I regulatory subunit alpha acts_upstream_of_or_within ISO MGI:2182091|MGI:3512112 (PMID:18316483) RGD PMID:18316483 NCBI chr10:95,120,537...95,139,028
Ensembl chr10:94,620,039...94,639,041 		JBrowse link
G Six4 SIX homeobox 4 involved_in ISO (PMID:21884692) RGD PMID:21884692 NCBI chr 6:91,802,328...91,816,002
Ensembl chr 6:91,802,329...91,815,992 		JBrowse link
G Srf serum response factor acts_upstream_of_or_within ISO
IEA 		MGI:3522206|MGI:3522214 (PMID:15569937)
GO_REF:0000107 		RGD
Ensembl		 PMID:15569937 GO_REF:0000107 NCBI chr 9:21,924,050...21,933,338
Ensembl chr 9:14,426,472...14,435,733 		JBrowse link
G Synpo2l synaptopodin 2-like involved_in ISO (PMID:29206857) RGD PMID:29206857 NCBI chr15:3,631,974...3,641,429
Ensembl chr15:3,631,834...3,641,429 		JBrowse link
G Tcap titin-cap involved_in ISO (PMID:9817758) RGD PMID:9817758 NCBI chr10:83,381,719...83,382,887
Ensembl chr10:83,381,719...83,382,887 		JBrowse link
G Tnnt2 troponin T2, cardiac type acts_upstream_of_or_within ISO MGI:3692448|MGI:3692450|MGI:3692451 (PMID:10449439) RGD PMID:10449439 NCBI chr13:47,267,325...47,285,390
Ensembl chr13:47,267,204...47,285,388 		JBrowse link
G Tpm1 tropomyosin 1 involved_in ISO
IEA 		(PMID:11273725)
GO_REF:0000107 		RGD
Ensembl		 PMID:11273725 GO_REF:0000107 NCBI chr 8:67,635,479...67,662,330
Ensembl chr 8:67,635,479...67,662,802 		JBrowse link
G Ttn titin involved_in
acts_upstream_of_or_within 		IDA
ISO 		(PMID:11846417), (PMID:9804419), (PMID:9817758)
MGI:3654306 (PMID:16702235), (PMID:17360664) 		RGD PMID:9804419 PMID:9817758 PMID:11846417 PMID:16702235 PMID:17360664 More... RGD:634444 NCBI chr 3:61,652,432...61,924,912
Ensembl chr 3:61,652,439...61,924,741 		JBrowse link
G Wdr1 WD repeat domain 1 involved_in
acts_upstream_of_or_within 		IBA
IEA
ISO 		GO_REF:0000033
GO_REF:0000107
(PMID:24840128) 		GO_Central
Ensembl
RGD		 PMID:24840128 GO_REF:0000033 GO_REF:0000107 NCBI chr14:76,470,238...76,504,086
Ensembl chr14:72,257,956...72,291,766 		JBrowse link
G Xirp1 xin actin-binding repeat containing 1 acts_upstream_of_or_within ISO MGI:3521795 (PMID:17766470) RGD PMID:17766470 NCBI chr 8:119,744,778...119,757,547
Ensembl chr 8:119,747,419...119,757,349 		JBrowse link
negative regulation of sarcomere organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav3 caveolin 3 involved_in ISO
IEA 		(PMID:12847114)
GO_REF:0000107 		RGD
Ensembl		 PMID:12847114 GO_REF:0000107 NCBI chr 4:145,582,168...145,598,142
Ensembl chr 4:145,582,060...145,598,137 		JBrowse link
G Mfn2 mitofusin 2 IMP RGD PMID:24777478 RGD:13204833 NCBI chr 5:163,587,463...163,617,363
Ensembl chr 5:158,304,287...158,335,342 		JBrowse link
positive regulation of sarcomere organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp10 bone morphogenetic protein 10 involved_in ISO
IEA 		(PMID:17921333)
GO_REF:0000107 		RGD
Ensembl		 PMID:17921333 GO_REF:0000107 NCBI chr 4:119,872,066...119,877,694
Ensembl chr 4:119,872,045...119,878,627 		JBrowse link
G Edn1 endothelin 1 involved_in ISO
IEA 		(PMID:12847114)
GO_REF:0000107 		RGD
Ensembl		 PMID:12847114 GO_REF:0000107 NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Ep300 E1A binding protein p300 IMP RGD PMID:12724418 RGD:2312280 NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088 		JBrowse link
G Mylk3 myosin light chain kinase 3 involved_in IDA PMID:17885681 BHF-UCL PMID:17885681 RGD:8554371 NCBI chr19:37,858,298...37,916,805
Ensembl chr19:21,691,929...21,742,954 		JBrowse link
G Prkd1 protein kinase D1 IMP RGD PMID:16648482 RGD:243065275 NCBI chr 6:73,460,640...73,774,433
Ensembl chr 6:67,725,905...68,039,042 		JBrowse link
G Prox1 prospero homeobox 1 involved_in ISO
IEA 		(PMID:19091769)
GO_REF:0000107 		RGD
Ensembl		 PMID:19091769 GO_REF:0000107 NCBI chr13:101,669,184...101,719,804
Ensembl chr13:101,669,184...101,711,183 		JBrowse link
regulation of sarcomere organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap13 A-kinase anchoring protein 13 involved_in ISS
ISO 		GO_REF:0000024
(PMID:20139090) 		UniProt
RGD		 PMID:20139090 GO_REF:0000024 NCBI chr 1:138,722,445...139,029,401
Ensembl chr 1:129,314,402...129,619,646 		JBrowse link
G Ankrd23 ankyrin repeat domain 23 acts_upstream_of_or_within ISO
IEA 		MGI:1097717|MGI:1861447 (PMID:17392382)
GO_REF:0000107 		RGD
Ensembl		 PMID:17392382 GO_REF:0000107 NCBI chr 9:38,773,234...38,778,705
Ensembl chr 9:38,773,240...38,779,839 		JBrowse link
G Hdac2 histone deacetylase 2 acts_upstream_of_or_within ISO MGI:3712002 (PMID:17322895) RGD PMID:17322895 NCBI chr20:42,101,815...42,126,486
Ensembl chr20:40,548,250...40,571,609 		JBrowse link
G Mef2c myocyte enhancer factor 2C acts_upstream_of_or_within ISO (PMID:17875930) RGD PMID:17875930 NCBI chr 2:15,708,732...15,871,639
Ensembl chr 2:13,993,438...14,132,880 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    developmental process 7160
      anatomical structure formation involved in morphogenesis 1384
        cellular component assembly involved in morphogenesis 150
          myofibril assembly 77
            sarcomere organization 55
              negative regulation of sarcomere organization 2
              positive regulation of sarcomere organization 6
              regulation of sarcomere organization + 12
Path 2
Term Annotations click to browse term
  biological_process 20543
    cellular process 19534
      cellular component organization or biogenesis 7114
        cellular component organization 6827
          organelle organization 3713
            cytoskeleton organization 1595
              actin cytoskeleton organization 770
                actomyosin structure organization 223
                  myofibril assembly 77
                    sarcomere organization 55
                      negative regulation of sarcomere organization 2
                      positive regulation of sarcomere organization 6
                      regulation of sarcomere organization + 12
paths to the root