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ONTOLOGY REPORT - ANNOTATIONS


Term:sarcomere organization
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Accession:GO:0045214 term browser browse the term
Definition:The myofibril assembly process that results in the organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
Synonyms:exact_synonym: sarcomere alignment;   sarcomere organisation
 alt_id: GO:0006938


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sarcomere organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actg1 actin, gamma 1 acts_upstream_of_or_within ISO (MGI:3053481|PMID:15194427) RGD PMID:15194427 MGI:3053481 NCBI chr10:109,518,429...109,521,288
Ensembl chr 3:75,643,054...75,644,954
Ensembl chr10:75,643,054...75,644,954
JBrowse link
G Actn1 actinin, alpha 1 involved_in ISS GO_REF:0000024 AgBase GO_REF:0000024 NCBI chr 6:103,376,557...103,470,497
Ensembl chr 6:103,375,799...103,470,555
JBrowse link
G Actn2 actinin alpha 2 involved_in ISO (PMID:25433700) RGD PMID:25433700 NCBI chr17:66,304,530...66,397,647
Ensembl chr17:66,304,501...66,397,653
JBrowse link
G Bmp10 bone morphogenetic protein 10 involved_in IMP PMID:17921333 BHF-UCL PMID:17921333 RGD:2302083 NCBI chr 4:119,224,906...119,230,534
Ensembl chr 4:119,225,040...119,230,728
JBrowse link
G Capn3 calpain 3 involved_in
acts_upstream_of_or_within
ISS
ISO
IEA
GO_REF:0000024
MGI:3046866 (MGI:3046122|PMID:15138196)
GO_REF:0000107
GO_REF:0000002
UniProt
RGD
Ensembl
InterPro
PMID:15138196 GO_REF:0000002 GO_REF:0000024 GO_REF:0000107 MGI:3046122 NCBI chr 3:112,227,486...112,278,408
Ensembl chr 3:112,228,720...112,278,408
JBrowse link
G Casq1 calsequestrin 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5306707|PMID:22049211)
UniProt
RGD
PMID:22049211 GO_REF:0000024 MGI:5306707 NCBI chr13:90,592,676...90,602,365
Ensembl chr13:90,592,681...90,602,365
JBrowse link
G Casq2 calsequestrin 2 involved_in ISO (MGI:4453101|PMID:19920148) RGD PMID:19920148 MGI:4453101 NCBI chr 2:204,512,361...204,568,643
Ensembl chr 2:204,512,302...204,568,656
JBrowse link
G Cfl2 cofilin 2 acts_upstream_of_or_within ISO MGI:2182095|MGI:5316051|MGI:5316057 (MGI:5316079|PMID:22343409) RGD PMID:22343409 MGI:5316079 NCBI chr 6:75,759,140...75,763,185
Ensembl chr 6:75,759,140...75,763,185
JBrowse link
G Csrp1 cysteine and glycine-rich protein 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:52,553,843...52,575,054
Ensembl chr13:52,553,775...52,575,051
JBrowse link
G Csrp2 cysteine and glycine-rich protein 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:53,630,675...53,649,309
Ensembl chr 7:53,630,621...53,649,310
JBrowse link
G Csrp3 cysteine and glycine rich protein 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:104,147,205...104,166,389
Ensembl chr 1:104,147,206...104,166,367
JBrowse link
G Fhod3 formin homology 2 domain containing 3 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
UniProtKB:F1LQJ2 (MGI:4422153|PMID:19706596)
RGD PMID:19706596, PMID:21873635 MGI:4422153, RGD:13792537 NCBI chr18:16,650,786...17,332,209
Ensembl chr18:16,650,806...17,332,210
JBrowse link
G Foxp1 forkhead box P1 acts_upstream_of_or_within ISO MGI:97350 (MGI:4829405|PMID:20713518) RGD PMID:20713518 MGI:4829405 NCBI chr 4:131,362,178...131,963,466
Ensembl chr 4:131,366,744...131,694,755
JBrowse link
G Itgb1 integrin subunit beta 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2154539 (MGI:84974|PMID:9004034)
Ensembl
RGD
PMID:9004034 GO_REF:0000107 MGI:84974 NCBI chr19:61,677,512...61,725,537
Ensembl chr19:61,677,542...61,725,535
JBrowse link
G Klhl41 kelch-like family member 41 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:55,910,177...55,923,303
Ensembl chr 3:55,910,177...55,923,303
JBrowse link
G Krt19 keratin 19 involved_in ISO (PMID:16000376) RGD PMID:16000376 NCBI chr10:88,055,843...88,060,560
Ensembl chr10:88,055,841...88,060,561
JBrowse link
G Krt8 keratin 8 involved_in IDA PMID:15247274 UniProt PMID:15247274 RGD:1600063 NCBI chr 7:143,596,511...143,603,745
Ensembl chr 7:143,596,511...143,603,803
JBrowse link
G Ldb3 LIM domain binding 3 acts_upstream_of_or_within ISO MGI:2652058 (MGI:2153618|PMID:11696561) RGD PMID:11696561 MGI:2153618 NCBI chr16:10,878,348...10,943,016
Ensembl chr16:10,878,334...10,941,501
JBrowse link
G Lmod2 leiomodin 2 involved_in ISO
IMP
(PMID:18403713)
(MGI:5787841|PMID:27274810)
RGD PMID:18403713 PMID:27274810, PMID:18403713 MGI:5787841, RGD:11344939 NCBI chr 4:51,553,439...51,561,135
Ensembl chr 4:51,553,454...51,561,174
JBrowse link
G Mybpc3 myosin binding protein C3 acts_upstream_of_or_within ISO MGI:2654420|MGI:3606208 (MGI:3616388|PMID:16380103), (MGI:3695637|PMID:17075052), (MGI:3696622|PMID:16224063) RGD PMID:16224063 PMID:16380103 PMID:17075052 MGI:3616388 MGI:3695637 MGI:3696622 NCBI chr 3:79,940,509...79,958,731
Ensembl chr 3:79,940,561...79,958,730
JBrowse link
G Myh6 myosin heavy chain 6 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3652543 (MGI:83539|PMID:8878443)
Ensembl
RGD
PMID:8878443 GO_REF:0000107 MGI:83539 NCBI chr15:33,605,653...33,629,730
Ensembl chr15:33,605,654...33,629,699
JBrowse link
G Mylk3 myosin light chain kinase 3 involved_in IBA
ISO
IMP
PMID:21873635
(MGI:3841874|PMID:18202317)
RGD PMID:18202317, PMID:21873635, PMID:18202317 MGI:3841874, RGD:13792537, RGD:8554765 NCBI chr19:27,388,163...27,442,451
Ensembl chr19:27,404,712...27,441,536
JBrowse link
G Myom2 myomesin 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:33033063)
Ensembl
RGD
PMID:33033063 GO_REF:0000107 NCBI chr16:79,587,136...79,672,871
Ensembl chr16:79,587,640...79,671,719
JBrowse link
G Myoz1 myozenin 1 involved_in ISO (MGI:3831256|PMID:18846255) RGD PMID:18846255 MGI:3831256 NCBI chr15:4,077,066...4,084,306
Ensembl chr15:4,077,091...4,084,314
JBrowse link
G Myoz2 myozenin 2 involved_in ISO (MGI:3513659|PMID:15543153) RGD PMID:15543153 MGI:3513659 NCBI chr 2:227,180,887...227,207,629
Ensembl chr 2:227,180,886...227,207,635
JBrowse link
G Mypn myopalladin involved_in ISO (PMID:11309420) RGD PMID:11309420 NCBI chr20:26,988,820...27,074,106
Ensembl chr20:26,988,774...27,074,138
JBrowse link
G Neurl2 neuralized E3 ubiquitin protein ligase 2 acts_upstream_of_or_within ISO MGI:3043523 (MGI:3042352|PMID:14960280) RGD PMID:14960280 MGI:3042352 NCBI chr 3:161,296,303...161,299,024
Ensembl chr 3:161,296,304...161,299,024
JBrowse link
G Nkx2-5 NK2 homeobox 5 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1914004 (MGI:4829405|PMID:20713518)
Ensembl
RGD
PMID:20713518 GO_REF:0000107 MGI:4829405 NCBI chr10:16,635,989...16,638,758
Ensembl chr10:16,635,989...16,638,764
JBrowse link
G Plec plectin involved_in ISO (MGI:5567855|PMID:24487589) RGD PMID:24487589 MGI:5567855 NCBI chr 7:117,230,319...117,291,859
Ensembl chr 7:117,230,319...117,289,961
JBrowse link
G Prkar1a protein kinase cAMP-dependent type I regulatory subunit alpha acts_upstream_of_or_within ISO MGI:2182091|MGI:3512112 (MGI:3821563|PMID:18316483) RGD PMID:18316483 MGI:3821563 NCBI chr10:97,940,705...97,959,199
Ensembl chr10:97,940,705...97,957,336
JBrowse link
G Six4 SIX homeobox 4 involved_in ISO (MGI:5298278|PMID:21884692) RGD PMID:21884692 MGI:5298278 NCBI chr 6:95,984,868...95,999,709
Ensembl chr 6:95,984,868...95,998,529
JBrowse link
G Srf serum response factor acts_upstream_of_or_within ISO MGI:3522206|MGI:3522214 (MGI:3513738|PMID:15569937) RGD PMID:15569937 MGI:3513738 NCBI chr 9:16,737,637...16,747,226
Ensembl chr 9:16,737,642...16,747,225
JBrowse link
G Synpo2l synaptopodin 2-like involved_in ISO (MGI:6102963|PMID:29206857) RGD PMID:29206857 MGI:6102963 NCBI chr15:4,064,706...4,074,151
Ensembl chr15:4,064,706...4,072,635
JBrowse link
G Tcap titin-cap involved_in IEA
ISO
GO_REF:0000107
(PMID:9817758)
Ensembl
RGD
PMID:9817758 GO_REF:0000107 NCBI chr10:86,337,705...86,338,414
Ensembl chr10:86,337,728...86,338,411
JBrowse link
G Tnnt1 troponin T1, slow skeletal type involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:72,889,270...72,899,629
Ensembl chr 1:72,889,270...72,899,659
JBrowse link
G Tnnt2 troponin T2, cardiac type involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:3692448|MGI:3692450|MGI:3692451 (MGI:1342889|PMID:10449439)
RGD PMID:10449439, PMID:21873635 MGI:1342889, RGD:13792537 NCBI chr13:52,662,974...52,680,992
Ensembl chr13:52,662,996...52,680,990
JBrowse link
G Tnnt3 troponin T3, fast skeletal type involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:215,666,628...215,683,628
Ensembl chr 1:215,666,628...215,683,628
JBrowse link
G Tpm1 tropomyosin 1 involved_in ISO
IEA
(PMID:11273725)
GO_REF:0000107
RGD
Ensembl
PMID:11273725 GO_REF:0000107 NCBI chr 8:72,814,737...72,841,496
Ensembl chr 8:72,814,740...72,842,228
JBrowse link
G Ttn titin acts_upstream_of_or_within
involved_in
IDA
ISO
MGI:3654306 (MGI:3653555|PMID:16702235), (MGI:3760201|PMID:17360664)
(PMID:11846417), (PMID:9817758)
RGD PMID:9817758 PMID:11846417 PMID:16702235 PMID:17360664, PMID:11034912 MGI:3653555 MGI:3760201, RGD:634444 NCBI chr 3:63,565,160...63,837,815 JBrowse link
G Wdr1 WD repeat domain 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:5574550|PMID:24840128)
RGD PMID:24840128, PMID:21873635 MGI:5574550, RGD:13792537 NCBI chr14:76,990,014...77,023,739
Ensembl chr14:76,989,919...77,023,726
JBrowse link
G Xirp1 xin actin-binding repeat containing 1 acts_upstream_of_or_within ISO MGI:3521795 (MGI:3775114|PMID:17766470) RGD PMID:17766470 MGI:3775114 NCBI chr 8:128,694,809...128,712,092
Ensembl chr 8:128,702,133...128,711,221
JBrowse link
negative regulation of sarcomere organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav3 caveolin 3 involved_in ISO (PMID:12847114) RGD PMID:12847114 NCBI chr 4:144,382,945...144,398,919
Ensembl chr 4:144,382,945...144,398,917
JBrowse link
G Mfn2 mitofusin 2 IMP RGD PMID:24777478 RGD:13204833 NCBI chr 5:164,684,244...164,715,414
Ensembl chr 5:164,684,509...164,714,145
JBrowse link
positive regulation of sarcomere organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp10 bone morphogenetic protein 10 involved_in ISO
IEA
(PMID:17921333)
GO_REF:0000107
RGD
Ensembl
PMID:17921333 GO_REF:0000107 NCBI chr 4:119,224,906...119,230,534
Ensembl chr 4:119,225,040...119,230,728
JBrowse link
G Edn1 endothelin 1 involved_in ISO (PMID:12847114) RGD PMID:12847114 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Ep300 E1A binding protein p300 IMP RGD PMID:12724418 RGD:2312280 NCBI chr 7:122,818,194...122,889,055
Ensembl chr 7:122,818,975...122,861,296
JBrowse link
G Mylk3 myosin light chain kinase 3 involved_in IDA PMID:17885681 BHF-UCL PMID:17885681 RGD:8554371 NCBI chr19:27,388,163...27,442,451
Ensembl chr19:27,404,712...27,441,536
JBrowse link
G Prox1 prospero homeobox 1 involved_in ISO (MGI:3830437|PMID:19091769) RGD PMID:19091769 MGI:3830437 NCBI chr13:108,382,536...108,444,107
Ensembl chr13:108,382,399...108,443,294
JBrowse link
regulation of sarcomere organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap13 A-kinase anchoring protein 13 involved_in ISS
ISO
GO_REF:0000024
(MGI:5308772|PMID:20139090)
UniProt
RGD
PMID:20139090 GO_REF:0000024 MGI:5308772 NCBI chr 1:137,089,558...137,315,272
Ensembl chr 1:137,014,272...137,315,272
JBrowse link
G Ankrd23 ankyrin repeat domain 23 acts_upstream_of_or_within ISO MGI:1097717|MGI:1861447 (MGI:3760007|PMID:17392382) RGD PMID:17392382 MGI:3760007 NCBI chr 9:43,110,980...43,117,585
Ensembl chr 9:43,112,141...43,116,521
JBrowse link
G Hdac2 histone deacetylase 2 acts_upstream_of_or_within ISO MGI:3712002 (MGI:3711360|PMID:17322895) RGD PMID:17322895 MGI:3711360 NCBI chr20:43,084,870...43,108,198
Ensembl chr20:43,084,870...43,108,198
JBrowse link
G Mef2c myocyte enhancer factor 2C acts_upstream_of_or_within ISO (MGI:3768576|PMID:17875930) RGD PMID:17875930 MGI:3768576 NCBI chr 2:11,658,534...11,822,788
Ensembl chr 2:11,658,568...11,822,787
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19599
    developmental process 6753
      anatomical structure formation involved in morphogenesis 1219
        cellular component assembly involved in morphogenesis 122
          myofibril assembly 70
            sarcomere organization 50
              negative regulation of sarcomere organization 2
              positive regulation of sarcomere organization 5
              regulation of sarcomere organization + 11
Path 2
Term Annotations click to browse term
  biological_process 19599
    cellular process 18451
      cellular component organization or biogenesis 6720
        cellular component organization 6475
          organelle organization 4054
            cytoskeleton organization 1447
              actin cytoskeleton organization 743
                actomyosin structure organization 210
                  myofibril assembly 70
                    sarcomere organization 50
                      negative regulation of sarcomere organization 2
                      positive regulation of sarcomere organization 5
                      regulation of sarcomere organization + 11
paths to the root