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ONTOLOGY REPORT - ANNOTATIONS

Term:basal part of cell
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Accession:GO:0045178 term browser browse the term
Definition:The region of a cell situated near the base. For example, in a polarized epithelial cell, the basal surface rests on the basal lamina that separates the epithelium from other tissue.

show annotations for term's descendants           Sort by:
 
basal part of cell term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy10 adenylate cyclase 10 IDA protein concentrated in apical membrane following treatment with acetozolamide RGD PMID:17959750 RGD:2313310 NCBI chr13:83,701,952...83,787,010
Ensembl chr13:83,721,300...83,787,018 		JBrowse link
G Cldn11 claudin 11 IEA
ISO		 GO_REF:0000107
(MGI:5510909|PMID:23789093)		 Ensembl
RGD		 PMID:23789093 GO_REF:0000107, MGI:5510909 NCBI chr 2:115,823,541...115,836,846
Ensembl chr 2:115,823,538...115,836,846 		JBrowse link
G Clrn1 clarin 1 IEA
ISO		 GO_REF:0000107
(MGI:4353969|PMID:19539019)		 Ensembl
RGD		 PMID:19539019 GO_REF:0000107, MGI:4353969 NCBI chr 2:149,049,925...149,088,787
Ensembl chr 2:149,049,925...149,088,787 		JBrowse link
G Edn1 endothelin 1 IDA RGD PMID:11174056 RGD:8662388 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324 		JBrowse link
G Eppk1 epiplakin 1 ISO (MGI:5604998|PMID:23599337) RGD PMID:23599337 MGI:5604998 NCBI chr 7:117,163,383...117,173,741 JBrowse link
G Fap fibroblast activation protein, alpha ISO (MGI:5522599|PMID:24038871) RGD PMID:24038871 MGI:5522599 NCBI chr 3:48,467,781...48,536,242
Ensembl chr 3:48,467,781...48,536,235 		JBrowse link
G Gkn2 gastrokine 2 ISO (MGI:5613885|PMID:25290738) RGD PMID:25290738 MGI:5613885 NCBI chr 4:119,131,255...119,177,329
Ensembl chr 4:119,171,245...119,177,329 		JBrowse link
G Hfe homeostatic iron regulator ISO (PMID:15880641) RGD PMID:15880641 NCBI chr17:43,661,276...43,669,327
Ensembl chr17:43,661,222...43,669,985 		JBrowse link
G Homer3 homer scaffold protein 3 ISO (MGI:3525625|PMID:12860966) RGD PMID:12860966 MGI:3525625 NCBI chr16:20,880,447...20,890,968
Ensembl chr16:20,881,518...20,890,949 		JBrowse link
G Itga1 integrin subunit alpha 1 ISO (MGI:2158011|PMID:11767049) RGD PMID:11767049 MGI:2158011 NCBI chr 2:47,127,403...47,281,387
Ensembl chr 2:47,127,219...47,281,421 		JBrowse link
G Itga2 integrin subunit alpha 2 ISO (MGI:2158011|PMID:11767049) RGD PMID:11767049 MGI:2158011 NCBI chr 2:46,996,904...47,097,011
Ensembl chr 2:47,000,323...47,096,961 		JBrowse link
G Itga6 integrin subunit alpha 6 ISO (MGI:2158011|PMID:11767049) RGD PMID:11767049 MGI:2158011 NCBI chr 3:58,442,904...58,515,124
Ensembl chr 3:58,443,101...58,515,124 		JBrowse link
G Krt14 keratin 14 ISO (MGI:5604998|PMID:23599337) RGD PMID:23599337 MGI:5604998 NCBI chr10:88,118,029...88,122,233
Ensembl chr10:88,055,823...88,122,233 		JBrowse link
G Mpp4 membrane palmitoylated protein 4 ISO (MGI:6094430|PMID:15914641) RGD PMID:15914641 MGI:6094430 NCBI chr 9:65,917,917...65,961,274
Ensembl chr 9:65,917,917...65,957,101 		JBrowse link
G Nrg1 neuregulin 1 ISO RGD RGD:11556218 NCBI chr16:62,969,573...64,065,063
Ensembl chr16:63,837,216...64,057,434 		JBrowse link
G Otof otoferlin IDA RGD PMID:23719817 RGD:9491749 NCBI chr 6:27,328,343...27,424,864
Ensembl chr 6:27,328,406...27,424,864 		JBrowse link
G Prcp prolylcarboxypeptidase ISO (MGI:5009114|PMID:21297000) RGD PMID:21297000 MGI:5009114 NCBI chr 1:157,701,089...157,750,177
Ensembl chr 1:157,701,089...157,750,169 		JBrowse link
G Reg1a regenerating family member 1 alpha IDA RGD PMID:12764608 RGD:9831428 NCBI chr 4:109,497,962...109,500,626
Ensembl chr 4:109,497,962...109,501,082 		JBrowse link
G Slc11a2 solute carrier family 11 member 2 IEA
ISO		 GO_REF:0000107
(PMID:15880641)		 Ensembl
RGD		 PMID:15880641 GO_REF:0000107 NCBI chr 7:142,025,812...142,062,892
Ensembl chr 7:142,025,815...142,063,212 		JBrowse link
G Syp synaptophysin ISO RGD RGD:11557984 NCBI chr  X:15,694,699...15,709,244
Ensembl chr  X:15,695,566...15,707,436 		JBrowse link
G Tf transferrin ISO (PMID:15880641) RGD PMID:15880641 NCBI chr 8:111,694,570...111,721,275
Ensembl chr 8:111,673,547...111,721,333 		JBrowse link
basal cortex term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clasp1 cytoplasmic linker associated protein 1 ISO
IBA		 (PMID:23940118)
PMID:21873635		 RGD PMID:23940118, PMID:21873635 RGD:13792537 NCBI chr13:34,365,038...34,584,651
Ensembl chr13:34,365,147...34,584,651 		JBrowse link
G Clasp2 cytoplasmic linker associated protein 2 ISO
IEA
IBA		 (PMID:23940118)
GO_REF:0000107
PMID:21873635		 RGD
Ensembl		 PMID:23940118, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 8:122,003,719...122,185,495
Ensembl chr 8:122,003,916...122,185,495 		JBrowse link
G Gck glucokinase IDA preferentially localized in regions closest to blood vessels in pancreatic beta cells of fed, not fasted, rats RGD PMID:10071239 RGD:2301948 NCBI chr14:86,149,146...86,191,589
Ensembl chr14:86,148,928...86,190,659 		JBrowse link
G Mark2 microtubule affinity regulating kinase 2 ISO (MGI:3582101|PMID:15950600) RGD PMID:15950600 MGI:3582101 NCBI chr 1:222,525,547...222,590,727
Ensembl chr 1:222,525,990...222,590,220 		JBrowse link
G Phldb1 pleckstrin homology-like domain, family B, member 1 IEA
IBA
ISO		 GO_REF:0000107
PMID:21873635
(PMID:23940118)		 Ensembl
RGD		 PMID:23940118, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 8:48,997,189...49,045,176
Ensembl chr 8:48,997,184...49,045,154 		JBrowse link
G Phldb2 pleckstrin homology-like domain, family B, member 2 ISO
IBA		 (PMID:23940118)
PMID:21873635		 RGD PMID:23940118, PMID:21873635 RGD:13792537 NCBI chr11:60,042,879...60,051,229
Ensembl chr11:57,265,732...57,481,589 		JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel ISO (PMID:10770959)
(MGI:4942265|PMID:10770959)		 RGD PMID:10770959 MGI:4942265 NCBI chr14:6,602,004...6,645,257
Ensembl chr14:6,602,004...6,645,257 		JBrowse link
basal plasma membrane term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 ISO
IEA
IDA		 (PMID:18619525)
GO_REF:0000107		 RGD
Ensembl		 PMID:18619525, PMID:18619525 GO_REF:0000107, RGD:2301072 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196 		JBrowse link
G Ace angiotensin I converting enzyme IDA RGD PMID:2841539 RGD:8157610 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822 		JBrowse link
G Ager advanced glycosylation end product-specific receptor IDA RGD PMID:9846897 RGD:1625351 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079 		JBrowse link
G Ank3 ankyrin 3 ISO
IEA		 (PMID:21223964)
GO_REF:0000107		 RGD
Ensembl		 PMID:21223964 GO_REF:0000107 NCBI chr20:19,948,767...20,480,628
Ensembl chr20:20,105,047...20,480,623 		JBrowse link
G Aqp1 aquaporin 1 ISO
ISS		 (PMID:17409744)
(MGI:5784975|PMID:23238222)
GO_REF:0000024		 RGD
UniProt		 PMID:17409744, PMID:23238222 GO_REF:0000024, MGI:5784975 NCBI chr 4:85,551,503...85,563,683
Ensembl chr 4:85,551,502...85,569,360 		JBrowse link
G Aqp4 aquaporin 4 IDA RGD PMID:9875338 RGD:8696009 NCBI chr18:6,766,009...6,782,757
Ensembl chr18:6,765,945...6,782,996 		JBrowse link
G Aqp5 aquaporin 5 ISO (MGI:2154040|PMID:11707570), (MGI:3617039|PMID:12042359) RGD PMID:11707570, PMID:12042359 MGI:2154040, MGI:3617039 NCBI chr 7:141,249,044...141,252,576
Ensembl chr 7:141,249,044...141,252,578 		JBrowse link
G Best1 bestrophin 1 ISO (PMID:31791063) RGD PMID:31791063 NCBI chr 1:226,033,146...226,049,893
Ensembl chr 1:226,030,875...226,049,929 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 IDA RGD PMID:16271518 RGD:5129481 NCBI chr 9:66,568,074...66,683,019
Ensembl chr 9:66,568,074...66,676,494 		JBrowse link
G C5ar2 complement component 5a receptor 2 ISO
ISS		 (PMID:22960554)
GO_REF:0000024		 RGD
UniProt		 PMID:22960554 GO_REF:0000024 NCBI chr 1:78,165,155...78,183,426
Ensembl chr 1:78,166,810...78,180,216 		JBrowse link
G Cav1 caveolin 1 IDA RGD PMID:16904002 RGD:1582171 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200 		JBrowse link
G Cd34 CD34 molecule IDA PMID:18319274 UniProt PMID:18319274 RGD:8553277 NCBI chr13:113,691,842...113,711,259
Ensembl chr13:113,691,932...113,711,647 		JBrowse link
G Cd81 Cd81 molecule ISO
IEA		 (PMID:31791063)
GO_REF:0000107		 RGD
Ensembl		 PMID:31791063 GO_REF:0000107 NCBI chr 1:216,237,663...216,253,460
Ensembl chr 1:216,237,697...216,253,311 		JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 IDA
IEA		 PMID:7774714
GO_REF:0000044		 UniProt PMID:7774714 GO_REF:0000044, RGD:11059576 NCBI chr 1:82,327,955...82,344,345
Ensembl chr 1:82,327,955...82,344,345 		JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 ISO (PMID:17478539) RGD PMID:17478539 NCBI chr17:63,990,599...64,463,222
Ensembl chr17:63,990,599...63,994,169 		JBrowse link
G Cldn4 claudin 4 IDA RGD PMID:15447685 RGD:2317603 NCBI chr12:24,761,210...24,763,008
Ensembl chr12:24,761,210...24,763,005 		JBrowse link
G Dag1 dystroglycan 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:116,980,501...116,993,182
Ensembl chr 8:116,980,497...116,993,193 		JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 IDA RGD PMID:7891172 RGD:1298878 NCBI chr11:72,164,566...72,378,895
Ensembl chr11:72,163,749...72,378,895 		JBrowse link
G Egfr epidermal growth factor receptor IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796 		JBrowse link
G Eps15 epidermal growth factor receptor pathway substrate 15 IDA RGD PMID:16625367 RGD:1600758 NCBI chr 5:128,923,809...129,022,268
Ensembl chr 5:128,923,934...129,022,054 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 IDA
IBA		 PMID:21873635 RGD
GO_Central		 PMID:15499570, PMID:21873635 RGD:1582108, RGD:13792537 NCBI chr10:86,367,596...86,391,728
Ensembl chr10:86,367,596...86,391,728 		JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:2,989,202...3,010,610
Ensembl chr 7:2,989,340...3,010,350 		JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:75,021,790...76,178,936
Ensembl chr 9:75,021,790...75,528,644 		JBrowse link
G Itga6 integrin subunit alpha 6 ISO (MGI:2150219|PMID:11507772), (MGI:4949803|PMID:21464233) RGD PMID:11507772, PMID:21464233 MGI:2150219, MGI:4949803 NCBI chr 3:58,442,904...58,515,124
Ensembl chr 3:58,443,101...58,515,124 		JBrowse link
G Itga9 integrin subunit alpha 9 ISO (MGI:71729|PMID:7534781) RGD PMID:7534781 MGI:71729 NCBI chr 8:127,271,029...127,576,709
Ensembl chr 8:127,271,289...127,572,988 		JBrowse link
G Itgb4 integrin subunit beta 4 ISO (MGI:2159597|PMID:11891657), (MGI:4949803|PMID:21464233) RGD PMID:11891657, PMID:21464233 MGI:2159597, MGI:4949803 NCBI chr10:104,524,000...104,560,180
Ensembl chr10:104,523,996...104,561,078 		JBrowse link
G Kcnq4 potassium voltage-gated channel subfamily Q member 4 IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr 5:139,625,783...139,677,300
Ensembl chr 5:139,627,576...139,677,300 		JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 ISO (PMID:12451172) RGD PMID:12451172 NCBI chr 5:152,964,294...152,987,286
Ensembl chr 5:152,966,591...152,987,211 		JBrowse link
G LOC102552659 receptor tyrosine-protein kinase erbB-2-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:84,839,053...84,845,803
Ensembl chr10:84,838,264...84,845,288 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase ISO
IBA
IEA		 (PMID:15314156)
PMID:21873635
GO_REF:0000107		 RGD
Ensembl		 PMID:15314156, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 4:44,747,467...44,854,628
Ensembl chr 4:44,774,741...44,852,665 		JBrowse link
G Mst1r macrophage stimulating 1 receptor IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:116,686,601...116,700,132
Ensembl chr 8:116,686,601...116,700,132 		JBrowse link
G Muc20 mucin 20, cell surface associated ISO (PMID:15314156) RGD PMID:15314156 NCBI chr11:71,222,602...71,236,223
Ensembl chr11:71,222,600...71,236,223 		JBrowse link
G Myo1a myosin IA IEA
ISO		 GO_REF:0000107
(MGI:1329200|PMID:9933937)		 Ensembl
RGD		 PMID:9933937 GO_REF:0000107, MGI:1329200 NCBI chr 7:71,000,299...71,019,386
Ensembl chr 7:71,004,417...71,019,372 		JBrowse link
G Myo1c myosin 1C ISO (PMID:9858156) RGD PMID:9858156 NCBI chr10:63,803,311...63,819,614
Ensembl chr10:63,803,309...63,819,614 		JBrowse link
G Oscp1 organic solute carrier partner 1 ISO (PMID:16006562) RGD PMID:16006562 NCBI chr 5:144,067,391...144,099,693
Ensembl chr 5:144,067,416...144,098,207 		JBrowse link
G P2ry12 purinergic receptor P2Y12 IDA RGD PMID:21879346 RGD:6480539 NCBI chr 2:149,440,807...149,482,592
Ensembl chr 2:149,441,598...149,444,548 		JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel ISO (PMID:10770959) RGD PMID:10770959 NCBI chr14:6,602,004...6,645,257
Ensembl chr14:6,602,004...6,645,257 		JBrowse link
G Plec plectin IDA RGD PMID:12389737 RGD:1599914 NCBI chr 7:117,230,319...117,291,859
Ensembl chr 7:117,230,319...117,289,961 		JBrowse link
G Rapgef3 Rap guanine nucleotide exchange factor 3 IDA RGD PMID:15464734 RGD:9835384 NCBI chr 7:139,232,263...139,254,668
Ensembl chr 7:139,232,251...139,254,551 		JBrowse link
G Rhcg Rh family, C glycoprotein IDA RGD PMID:20392801 RGD:9850153 NCBI chr 1:141,325,854...141,349,881
Ensembl chr 1:141,325,856...141,349,881 		JBrowse link
G Shroom4 shroom family member 4 ISO (MGI:3693190|PMID:17009331) RGD PMID:17009331 MGI:3693190 NCBI chr  X:16,723,360...16,929,829
Ensembl chr  X:16,719,803...16,929,907 		JBrowse link
G Slc12a2 solute carrier family 12 member 2 ISO (PMID:17478539) RGD PMID:17478539 NCBI chr18:52,917,124...52,985,281
Ensembl chr18:52,917,124...52,985,261 		JBrowse link
G Slc16a1 solute carrier family 16 member 1 ISO (PMID:26854723) RGD PMID:26854723 NCBI chr 2:207,108,552...207,129,352
Ensembl chr 2:207,108,552...207,128,554 		JBrowse link
G Slc16a8 solute carrier family 16 member 8 IDA RGD PMID:9841555 RGD:68849 NCBI chr 7:120,486,266...120,490,192
Ensembl chr 7:120,486,266...120,490,061 		JBrowse link
G Slc1a3 solute carrier family 1 member 3 IDA PMID:26133720 ARUK-UCL PMID:26133720 RGD:11054956 NCBI chr 2:57,860,881...57,935,363
Ensembl chr 2:57,860,834...57,935,363 		JBrowse link
G Slc1a5 solute carrier family 1 member 5 ISO (MGI:6393124|PMID:14622120) RGD PMID:14622120 MGI:6393124 NCBI chr 1:78,710,686...78,724,789
Ensembl chr 1:78,710,539...78,724,794 		JBrowse link
G Slc23a1 solute carrier family 23 member 1 IDA
ISO		 PMID:18668520
(MGI:4365346|PMID:18668520)		 RGD PMID:18668520, PMID:18668520 MGI:4365346, RGD:8554811 NCBI chr18:28,413,910...28,428,133
Ensembl chr18:28,414,009...28,428,117 		JBrowse link
G Slc23a2 solute carrier family 23 member 2 IDA
ISO		 PMID:18668520
(MGI:4365346|PMID:18668520)		 RGD PMID:18668520, PMID:18668520 MGI:4365346, RGD:8554811 NCBI chr 3:124,632,491...124,842,225
Ensembl chr 3:124,632,492...124,724,252 		JBrowse link
G Slc27a1 solute carrier family 27 member 1 IEA
ISO		 GO_REF:0000107
(MGI:6414733|PMID:28035674)		 Ensembl
RGD		 PMID:28035674 GO_REF:0000107, MGI:6414733 NCBI chr16:19,997,823...20,016,193
Ensembl chr16:19,999,112...20,016,190 		JBrowse link
G Slc27a5 solute carrier family 27 member 5 ISO (MGI:3722951|PMID:16618416) RGD PMID:16618416 MGI:3722951 NCBI chr 1:65,576,599...65,587,192
Ensembl chr 1:65,576,535...65,587,186 		JBrowse link
G Slc3a2 solute carrier family 3 member 2 IDA PMID:11095508 ARUK-UCL PMID:11095508 RGD:30309922 NCBI chr 1:224,906,566...224,921,029
Ensembl chr 1:224,906,554...224,921,092 		JBrowse link
G Slc5a6 solute carrier family 5 member 6 ISO (PMID:25809983) RGD PMID:25809983 NCBI chr 6:26,685,823...26,697,110
Ensembl chr 6:26,686,033...26,697,116 		JBrowse link
G Slc6a9 solute carrier family 6 member 9 ISO (PMID:11159884) RGD PMID:11159884 NCBI chr 5:136,669,674...136,703,702
Ensembl chr 5:136,669,674...136,703,697 		JBrowse link
G Slc7a1 solute carrier family 7 member 1 IDA PMID:19712052
PMID:29247719		 ARUK-UCL PMID:19712052, PMID:29247719 RGD:30309907, RGD:30309915 NCBI chr12:8,032,775...8,108,972
Ensembl chr12:8,032,809...8,108,972 		JBrowse link
G Slc7a5 solute carrier family 7 member 5 IDA PMID:18619525
PMID:11095508		 ARUK-UCL PMID:18619525, PMID:11095508 RGD:2301072, RGD:30309922 NCBI chr19:54,693,959...54,722,563
Ensembl chr19:54,693,959...54,722,563 		JBrowse link
G Slc7a8 solute carrier family 7 member 8 ISO (PMID:26050671) RGD PMID:26050671 NCBI chr15:33,369,245...33,428,942
Ensembl chr15:33,369,216...33,428,973 		JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 IDA PMID:18619525 ARUK-UCL PMID:18619525 RGD:2301072 NCBI chr 4:175,969,549...176,026,227
Ensembl chr 4:175,969,549...176,026,163 		JBrowse link
G Tacstd2 tumor-associated calcium signal transducer 2 IEA
ISO
ISS		 GO_REF:0000107
(MGI:5315060|PMID:22194864)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:22194864 GO_REF:0000024, GO_REF:0000107, MGI:5315060 NCBI chr 4:98,341,187...98,342,887
Ensembl chr 4:98,341,188...98,342,887 		JBrowse link
G Tek TEK receptor tyrosine kinase ISO (PMID:18425120) RGD PMID:18425120 NCBI chr 5:113,725,717...113,852,799
Ensembl chr 5:113,725,717...113,852,799 		JBrowse link
G Tf transferrin ISO (PMID:15880641) RGD PMID:15880641 NCBI chr 8:111,694,570...111,721,275
Ensembl chr 8:111,673,547...111,721,333 		JBrowse link
basolateral part of cell term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rapgef3 Rap guanine nucleotide exchange factor 3 IDA RGD PMID:18495799 RGD:2314762 NCBI chr 7:139,232,263...139,254,668
Ensembl chr 7:139,232,251...139,254,551 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20602
    cellular anatomical entity 20292
      basal part of cell 85
        basal cortex 7
        basal labyrinth 0
        basal plasma membrane 60
        basolateral part of cell 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.