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ONTOLOGY REPORT - ANNOTATIONS

Term:neuronal ion channel clustering
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Accession:GO:0045161 term browser browse the term
Definition:The process in which voltage-gated ion channels become localized to distinct subcellular domains in the neuron. Specific targeting, clustering, and maintenance of these channels in their respective domains are essential to achieve high conduction velocities of action potential propagation.


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neuronal ion channel clustering term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dlg2 discs large MAGUK scaffold protein 2 IMP RGD PMID:8755482 RGD:728660 NCBI chr 1:144,451,653...146,503,949
Ensembl chr 1:144,451,472...146,499,475 		JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 involved_in TAS PMID:11152698 UniProt PMID:11152698 RGD:8554109 NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153 		JBrowse link
G Nlgn1 neuroligin 1 involved_in TAS PMID:9278515 UniProt PMID:9278515 RGD:8554758 NCBI chr 2:108,256,236...109,181,530
Ensembl chr 2:108,257,824...109,002,464 		JBrowse link
G Pmp22 peripheral myelin protein 22 acts_upstream_of_or_within ISO MGI:1856217 (PMID:15703401) RGD PMID:15703401 NCBI chr10:47,795,709...47,825,715
Ensembl chr10:47,795,709...47,825,714 		JBrowse link
clustering of voltage-gated calcium channels term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap5 A-kinase anchoring protein 5 involved_in ISO (MGI:6378147|PMID:27693258) RGD PMID:27693258 MGI:6378147 NCBI chr 6:95,051,527...95,061,075
Ensembl chr 6:95,051,537...95,061,578 		JBrowse link
clustering of voltage-gated potassium channels term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap5 A-kinase anchoring protein 5 involved_in ISO (MGI:6378147|PMID:27693258) RGD PMID:27693258 MGI:6378147 NCBI chr 6:95,051,527...95,061,075
Ensembl chr 6:95,051,537...95,061,578 		JBrowse link
G Cntn2 contactin 2 involved_in IEA
ISO		 GO_REF:0000107
(MGI:2675531|PMID:12963709)		 Ensembl
RGD		 PMID:12963709 GO_REF:0000107 MGI:2675531 NCBI chr13:43,942,868...43,975,973
Ensembl chr13:43,947,265...43,975,887 		JBrowse link
G Cntnap2 contactin associated protein 2 involved_in ISO MGI:2677631 (MGI:2675531|PMID:12963709), (PMID:29300891) RGD PMID:12963709 PMID:29300891 MGI:2675531 NCBI chr 4:74,109,455...76,366,434
Ensembl chr 4:74,109,472...76,362,027 		JBrowse link
G Dlg2 discs large MAGUK scaffold protein 2 involved_in ISO MGI:2388036 (PMID:18509034) RGD PMID:18509034 NCBI chr 1:144,451,653...146,503,949
Ensembl chr 1:144,451,472...146,499,475 		JBrowse link
G Kcnb1 potassium voltage-gated channel subfamily B member 1 IDA RGD PMID:24355600 RGD:126908004 NCBI chr 3:155,820,255...155,913,383
Ensembl chr 3:155,822,963...155,916,194 		JBrowse link
G Kcnip2 potassium voltage-gated channel interacting protein 2 involved_in IDA
IMP
ISO		 (PMID:11287421) RGD PMID:11287421 PMID:12967630 PMID:12006572 RGD:7207200, RGD:625553 NCBI chr 1:244,641,147...244,664,939
Ensembl chr 1:244,641,150...244,664,874 		JBrowse link
G Kcnip2_v1 potassium voltage-gated channel interacting protein 2, variant 1 IMP RGD PMID:12006572 RGD:625553
G Kcnip2_v2 potassium voltage-gated channel interacting protein 2, variant 2 IMP RGD PMID:12006572 RGD:625553
G Kcnip2_v3 potassium voltage-gated channel interacting protein 2, variant 3 IMP RGD PMID:12006572 RGD:625553
clustering of voltage-gated sodium channels term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ank3 ankyrin 3 IMP RGD PMID:17709431 RGD:14392774 NCBI chr20:18,602,267...19,225,831
Ensembl chr20:18,602,786...19,086,300 		JBrowse link
G Gldn gliomedin involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:4840020 (PMID:20188654)		 Ensembl
RGD		 PMID:20188654 GO_REF:0000107 NCBI chr 8:54,679,015...54,723,198
Ensembl chr 8:54,679,119...54,723,196 		JBrowse link
G Myoc myocilin involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:5527213|PMID:23897819)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:23897819 GO_REF:0000024 GO_REF:0000107 MGI:5527213 NCBI chr13:74,976,730...74,987,128
Ensembl chr13:74,976,730...74,987,127 		JBrowse link
G Nfasc neurofascin acts_upstream_of_or_within ISO MGI:3808598 (PMID:20188654) RGD PMID:20188654 NCBI chr13:43,997,223...44,183,863
Ensembl chr13:43,997,224...44,183,880 		JBrowse link
G Nrcam neuronal cell adhesion molecule involved_in
acts_upstream_of_or_within		 ISO
IEA
ISS		 (PMID:14602817)
MGI:2387976 (PMID:20188654)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:14602817 PMID:20188654 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:61,402,813...61,698,536
Ensembl chr 6:61,329,863...61,702,992 		JBrowse link
G Sclt1 sodium channel and clathrin linker 1 involved_in IMP
IEA		 GO_REF:0000002 InterPro
RGD		 PMID:15797711 GO_REF:0000002, RGD:1359053 NCBI chr 2:124,605,445...124,763,964
Ensembl chr 2:124,605,658...124,764,065 		JBrowse link
G Sptbn4 spectrin, beta, non-erythrocytic 4 involved_in
acts_upstream_of_or_within		 ISO (MGI:2181223|PMID:11807096)
MGI:3710201 (PMID:17197442)		 RGD PMID:11807096 PMID:17197442 MGI:2181223 NCBI chr 1:82,650,750...82,738,345
Ensembl chr 1:82,650,751...82,737,228 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20292
    cellular process 18769
      cellular developmental process 4747
        cell maturation 257
          neuron maturation 75
            neuronal ion channel clustering 19
              clustering of voltage-gated calcium channels 1
              clustering of voltage-gated potassium channels 9
              clustering of voltage-gated sodium channels 7
Path 2
Term Annotations click to browse term
  biological_process 20292
    developmental process 7042
      anatomical structure development 6550
        multicellular organism development 5276
          system development 4559
            nervous system development 2819
              neurogenesis 2091
                generation of neurons 1803
                  neuron differentiation 1721
                    neuron development 1419
                      neuron maturation 75
                        neuronal ion channel clustering 19
                          clustering of voltage-gated calcium channels 1
                          clustering of voltage-gated potassium channels 9
                          clustering of voltage-gated sodium channels 7
paths to the root