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ONTOLOGY REPORT - ANNOTATIONS


Term:neuronal ion channel clustering
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Accession:GO:0045161 term browser browse the term
Definition:The process in which voltage-gated ion channels become localized to distinct subcellular domains in the neuron. Specific targeting, clustering, and maintenance of these channels in their respective domains are essential to achieve high conduction velocities of action potential propagation.


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neuronal ion channel clustering term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dlg2 discs large MAGUK scaffold protein 2 IMP RGD PMID:8755482 RGD:728660 NCBI chr 1:144,451,653...146,503,949
Ensembl chr 1:144,451,472...146,499,475
JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 involved_in TAS PMID:11152698 UniProt PMID:11152698 RGD:8554109 NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153
JBrowse link
G Nlgn1 neuroligin 1 involved_in TAS PMID:9278515 UniProt PMID:9278515 RGD:8554758 NCBI chr 2:108,256,236...109,181,530
Ensembl chr 2:108,257,824...109,002,464
JBrowse link
G Pmp22 peripheral myelin protein 22 acts_upstream_of_or_within ISO MGI:1856217 (MGI:3577677|PMID:15703401) RGD PMID:15703401 MGI:3577677 NCBI chr10:47,795,709...47,825,715
Ensembl chr10:47,795,709...47,825,714
JBrowse link
clustering of voltage-gated calcium channels term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap5 A-kinase anchoring protein 5 involved_in ISO (MGI:6378147|PMID:27693258) RGD PMID:27693258 MGI:6378147 NCBI chr 6:95,051,527...95,061,075
Ensembl chr 6:95,051,537...95,061,578
JBrowse link
clustering of voltage-gated potassium channels term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap5 A-kinase anchoring protein 5 involved_in ISO (MGI:6378147|PMID:27693258) RGD PMID:27693258 MGI:6378147 NCBI chr 6:95,051,527...95,061,075
Ensembl chr 6:95,051,537...95,061,578
JBrowse link
G Cntn2 contactin 2 involved_in IEA
ISO
GO_REF:0000107
(MGI:2675531|PMID:12963709)
Ensembl
RGD
PMID:12963709 GO_REF:0000107 MGI:2675531 NCBI chr13:43,942,868...43,975,973
Ensembl chr13:43,947,265...43,975,887
JBrowse link
G Cntnap2 contactin associated protein 2 involved_in ISO MGI:2677631 (MGI:2675531|PMID:12963709), (MGI:6392103|PMID:29300891) RGD PMID:12963709 PMID:29300891 MGI:2675531 MGI:6392103 NCBI chr 4:74,109,455...76,366,434
Ensembl chr 4:74,109,472...76,362,027
JBrowse link
G Kcnip2 potassium voltage-gated channel interacting protein 2 involved_in IDA
ISO
IMP
(PMID:11287421) RGD PMID:11287421 PMID:12967630 PMID:12006572 RGD:7207200, RGD:625553 NCBI chr 1:244,641,147...244,664,939
Ensembl chr 1:244,641,150...244,664,874
JBrowse link
G Kcnip2_v1 potassium voltage-gated channel interacting protein 2, variant 1 IMP RGD PMID:12006572 RGD:625553
G Kcnip2_v2 potassium voltage-gated channel interacting protein 2, variant 2 IMP RGD PMID:12006572 RGD:625553
G Kcnip2_v3 potassium voltage-gated channel interacting protein 2, variant 3 IMP RGD PMID:12006572 RGD:625553
clustering of voltage-gated sodium channels term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ank3 ankyrin 3 IMP RGD PMID:17709431 RGD:14392774 NCBI chr20:18,602,267...19,225,831
Ensembl chr20:18,602,786...19,086,300
JBrowse link
G Gldn gliomedin involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:4840020 (MGI:4839704|PMID:20188654)
Ensembl
RGD
PMID:20188654 GO_REF:0000107 MGI:4839704 NCBI chr 8:54,679,015...54,723,198
Ensembl chr 8:54,679,119...54,723,196
JBrowse link
G Myoc myocilin involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:5527213|PMID:23897819)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:23897819 GO_REF:0000024 GO_REF:0000107 MGI:5527213 NCBI chr13:74,976,730...74,987,128
Ensembl chr13:74,976,730...74,987,127
JBrowse link
G Nfasc neurofascin acts_upstream_of_or_within ISO MGI:3808598 (MGI:4839704|PMID:20188654) RGD PMID:20188654 MGI:4839704 NCBI chr13:43,997,223...44,183,863
Ensembl chr13:43,997,224...44,183,880
JBrowse link
G Nrcam neuronal cell adhesion molecule involved_in
acts_upstream_of_or_within
IEA
ISO
ISS
GO_REF:0000107
MGI:2387976 (MGI:4839704|PMID:20188654)
GO_REF:0000024
(PMID:14602817)
Ensembl
RGD
UniProt
PMID:14602817 PMID:20188654 GO_REF:0000024 GO_REF:0000107 MGI:4839704 NCBI chr 6:61,402,813...61,698,536
Ensembl chr 6:61,329,863...61,702,992
JBrowse link
G Sclt1 sodium channel and clathrin linker 1 IMP RGD PMID:15797711 RGD:1359053 NCBI chr 2:124,605,445...124,763,964
Ensembl chr 2:124,605,658...124,764,065
JBrowse link
G Sptbn4 spectrin, beta, non-erythrocytic 4 involved_in
acts_upstream_of_or_within
ISO (MGI:2181223|PMID:11807096)
MGI:3710201 (MGI:3708238|PMID:17197442)
RGD PMID:11807096 PMID:17197442 MGI:2181223 MGI:3708238 NCBI chr 1:82,650,750...82,738,345
Ensembl chr 1:82,650,751...82,737,228
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    cellular process 18340
      cellular developmental process 4478
        cell maturation 229
          neuron maturation 66
            neuronal ion channel clustering 18
              clustering of voltage-gated calcium channels 1
              clustering of voltage-gated potassium channels 7
              clustering of voltage-gated sodium channels 7
Path 2
Term Annotations click to browse term
  biological_process 19492
    developmental process 6770
      anatomical structure development 6196
        multicellular organism development 5633
          system development 5301
            nervous system development 2733
              neurogenesis 1953
                generation of neurons 1795
                  neuron differentiation 1624
                    neuron development 1335
                      neuron maturation 66
                        neuronal ion channel clustering 18
                          clustering of voltage-gated calcium channels 1
                          clustering of voltage-gated potassium channels 7
                          clustering of voltage-gated sodium channels 7
paths to the root