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ONTOLOGY REPORT - ANNOTATIONS

Term:development of secondary sexual characteristics
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Accession:GO:0045136 term browser browse the term
Definition:The process whose specific outcome is the progression of the secondary sexual characteristics over time, from their formation to the mature structures. In humans, these include growth of axillary, chest, and pubic hair, voice changes, testicular/penile enlargement, breast development and menstrual periods. Development occurs in response to sex hormone secretion.


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development of secondary sexual characteristics term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B4galt1 beta-1,4-galactosyltransferase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2178779 (MGI:2178150|PMID:11900463)		 Ensembl
RGD		 PMID:11900463 GO_REF:0000107 MGI:2178150 NCBI chr 5:55,935,614...55,982,461
Ensembl chr 5:55,935,615...55,982,461 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857429 (MGI:3580738|PMID:15944391)		 Ensembl
RGD		 PMID:15944391 GO_REF:0000107 MGI:3580738 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
development of secondary female sexual characteristics term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irf2bpl interferon regulatory factor 2 binding protein-like involved_in IMP PMID:17627301 ParkinsonsUK-UCL PMID:17627301 RGD:8655531 NCBI chr 6:106,527,179...106,531,294
Ensembl chr 6:106,528,053...106,530,401 		JBrowse link
G Nell2 neural EGFL like 2 involved_in IMP PMID:18547942 UniProt PMID:18547942 RGD:10047268 NCBI chr 7:126,343,089...126,662,694
Ensembl chr 7:126,198,851...126,733,503 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A acts_upstream_of_or_within ISO MGI:2181607 (MGI:2181561|PMID:9630227) RGD PMID:9630227 MGI:2181561 NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866 		JBrowse link
G Stat5b signal transducer and activator of transcription 5B involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2181609 (MGI:2181561|PMID:9630227)		 Ensembl
RGD		 PMID:9630227 GO_REF:0000107 MGI:2181561 NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668 		JBrowse link
development of secondary male sexual characteristics term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lhcgr luteinizing hormone/choriogonadotropin receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2181999 (MGI:1929316|PMID:11145748)		 Ensembl
RGD		 PMID:11145748 GO_REF:0000107 MGI:1929316 NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A acts_upstream_of_or_within ISO MGI:103035|MGI:2181607 (MGI:2181561|PMID:9630227) RGD PMID:9630227 MGI:2181561 NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866 		JBrowse link
G Stat5b signal transducer and activator of transcription 5B involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:103036|MGI:2181609 (MGI:2181561|PMID:9630227)		 Ensembl
RGD		 PMID:9630227 GO_REF:0000107 MGI:2181561 NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668 		JBrowse link
mammary gland branching involved in thelarche term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Areg amphiregulin acts_upstream_of_or_within ISO MGI:2176531 (MGI:1336843|PMID:10331984), (MGI:3703920|PMID:17369357) RGD PMID:10331984 PMID:17369357 MGI:1336843 MGI:3703920 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535 		JBrowse link
G Med1 mediator complex subunit 1 acts_upstream_of_or_within ISO MGI:3511276 (MGI:3576991|PMID:15647257) RGD PMID:15647257 MGI:3576991 NCBI chr10:83,145,538...83,189,260
Ensembl chr10:83,145,568...83,189,299 		JBrowse link
G Ncoa3 nuclear receptor coactivator 3 acts_upstream_of_or_within ISO MGI:1931860 (MGI:1859522|PMID:11015591) RGD PMID:11015591 MGI:1859522 NCBI chr 3:154,738,566...154,821,395
Ensembl chr 3:154,738,581...154,818,594 		JBrowse link
G Phb2 prohibitin 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:3574361 (MGI:3695669|PMID:17065319)
GO_REF:0000107		 RGD
Ensembl		 PMID:17065319 GO_REF:0000107 MGI:3695669 NCBI chr 4:157,517,662...157,522,268
Ensembl chr 4:157,517,577...157,522,272 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 acts_upstream_of_or_within ISO MGI:1857258 (MGI:3814777|PMID:18614704) RGD PMID:18614704 MGI:3814777 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Wnt5a Wnt family member 5A involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:3761053|PMID:17898001)		 Ensembl
RGD		 PMID:17898001 GO_REF:0000107 MGI:3761053 NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19834
    reproductive process 1848
      developmental process involved in reproduction 1227
        development of secondary sexual characteristics 13
          development of secondary female sexual characteristics + 10
          development of secondary male sexual characteristics 3
Path 2
Term Annotations click to browse term
  biological_process 19834
    reproduction 1851
      reproductive process 1848
        developmental process involved in reproduction 1227
          development of secondary sexual characteristics 13
            development of secondary female sexual characteristics + 10
            development of secondary male sexual characteristics 3
paths to the root