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ONTOLOGY REPORT - ANNOTATIONS

Term:aflatoxin biosynthetic process
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Accession:GO:0045122 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450.
Synonyms:exact_synonym: aflatoxin anabolism;   aflatoxin biosynthesis;   aflatoxin formation;   aflatoxin synthesis


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Path 1
Term Annotations click to browse term
  biological_process 28573
    metabolic process 11001
      secondary metabolic process 74
        secondary metabolite biosynthetic process 27
          toxin biosynthetic process 1
            mycotoxin biosynthetic process 0
              aflatoxin biosynthetic process 0
                negative regulation of aflatoxin biosynthetic process 0
                positive regulation of aflatoxin biosynthetic process 0
                regulation of aflatoxin biosynthetic process + 0
Path 2
Term Annotations click to browse term
  biological_process 28573
    cellular process 17545
      cellular metabolic process 9207
        organic acid metabolic process 1020
          oxoacid metabolic process 1013
            carboxylic acid metabolic process 991
              monocarboxylic acid metabolic process 735
                acetate metabolic process 4
                  aflatoxin biosynthetic process 0
                    negative regulation of aflatoxin biosynthetic process 0
                    positive regulation of aflatoxin biosynthetic process 0
                    regulation of aflatoxin biosynthetic process + 0
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