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ONTOLOGY REPORT - ANNOTATIONS

Term:cytotoxic T cell differentiation
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Accession:GO:0045065 term browser browse the term
Definition:The process in which a relatively unspecialized T cell acquires specialized features of a cytotoxic T cell.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: cytotoxic T lymphocyte selection;   cytotoxic T-cell selection
 related_synonym: cytotoxic T cell development

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cytotoxic T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd8a CD8 subunit alpha acts_upstream_of_or_within
involved_in 		ISO
IEA 		(PMID:1673361) MGI
TreeGrafter		 PMID:1673361 GO_REF:0000118 NCBI chrNW_004936712:885,301...891,247
Ensembl chrNW_004936712:885,458...890,852 		JBrowse link
positive regulation of cytotoxic T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sart1 spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936599:3,577,552...3,588,825
Ensembl chrNW_004936599:3,577,480...3,588,706 		JBrowse link
G Tnfsf9 TNF superfamily member 9 ISO RGD PMID:19187795 RGD:2317344 NCBI chrNW_004936588:3,844,924...3,847,218 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17413
    immune system process 2310
      leukocyte activation 952
        lymphocyte activation 778
          lymphocyte differentiation 418
            T cell differentiation 312
              cytotoxic T cell differentiation 3
                CD8-positive, alpha-beta cytotoxic T cell differentiation 0
                negative regulation of cytotoxic T cell differentiation 0
                positive regulation of cytotoxic T cell differentiation 2
                regulation of cytotoxic T cell differentiation + 2
Path 2
Term Annotations click to browse term
  biological_process 17413
    developmental process 6463
      cellular developmental process 4360
        cell differentiation 4359
          cell development 3130
            hemopoiesis 990
              leukocyte differentiation 633
                mononuclear cell differentiation 511
                  lymphocyte differentiation 418
                    T cell differentiation 312
                      cytotoxic T cell differentiation 3
                        CD8-positive, alpha-beta cytotoxic T cell differentiation 0
                        negative regulation of cytotoxic T cell differentiation 0
                        positive regulation of cytotoxic T cell differentiation 2
                        regulation of cytotoxic T cell differentiation + 2
paths to the root