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ONTOLOGY REPORT - ANNOTATIONS


Term:constitutive secretory pathway
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Accession:GO:0045054 term browser browse the term
Definition:A process of exocytosis found in all eukaryotic cells, in which transport vesicles destined for the plasma membrane leave the trans-Golgi network in a steady stream. Upon exocytosis, the membrane proteins and lipids in these vesicles provide new components for the plasma membrane, and the soluble proteins inside the vesicles are released into the extracellular space.
Synonyms:exact_synonym: constitutive exocytosis



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constitutive secretory pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rab11b RAB11B, member RAS oncogene family involved_in IMP
IBA
ISO
PMID:14627637
PMID:21873635
(PMID:14627637)
RGD PMID:14627637 PMID:14627637 PMID:21873635 RGD:8554199, RGD:13792537 NCBI chr 7:14,521,448...14,534,589
Ensembl chr 7:14,521,368...14,534,593
JBrowse link
G Tmem167a transmembrane protein 167A involved_in ISO UniProtKB:Q9NRX6 (PMID:19942856) RGD PMID:19942856 NCBI chr 2:21,197,728...21,216,746
Ensembl chr 2:21,197,786...21,212,099
JBrowse link
G Tmem167b transmembrane protein 167B involved_in ISO UniProtKB:Q8TBQ9 (PMID:19942856) RGD PMID:19942856 NCBI chr 2:196,194,355...196,198,134
Ensembl chr 2:196,192,185...196,198,158
JBrowse link
G Trappc11 trafficking protein particle complex subunit 11 involved_in ISO (PMID:19942856) RGD PMID:19942856 NCBI chr16:44,733,169...44,779,324
Ensembl chr16:44,733,169...44,779,322
JBrowse link
negative regulation of constitutive secretory pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rab33b RAB33B, member RAS oncogene family involved_in ISO (PMID:22899725) RGD PMID:22899725 NCBI chr 2:135,528,116...135,538,719
Ensembl chr 2:135,528,116...135,538,719
JBrowse link
positive regulation of constitutive secretory pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rab27a RAB27A, member RAS oncogene family involved_in ISO (PMID:22899725) RGD PMID:22899725 NCBI chr 8:73,782,730...73,836,630
Ensembl chr 8:73,782,694...73,847,829
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19504
    cellular process 18357
      vesicle-mediated transport 1674
        exocytosis 424
          constitutive secretory pathway 6
            negative regulation of constitutive secretory pathway 1
            positive regulation of constitutive secretory pathway 1
            regulation of constitutive secretory pathway + 2
Path 2
Term Annotations click to browse term
  biological_process 19504
    localization 6451
      establishment of localization 4866
        transport 4702
          secretion 1159
            secretion by cell 963
              exocytosis 424
                constitutive secretory pathway 6
                  negative regulation of constitutive secretory pathway 1
                  positive regulation of constitutive secretory pathway 1
                  regulation of constitutive secretory pathway + 2
paths to the root