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ONTOLOGY REPORT - ANNOTATIONS

Term:protein insertion into ER membrane
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Accession:GO:0045048 term browser browse the term
Definition:The process that results in incorporation of a protein into an endoplasmic reticulum (ER) membrane. It depends on specific topogenic sequences of amino acids that ensure that a protein acquires the proper orientation during its insertion into the ER membrane.
Synonyms:exact_synonym: integral ER membrane protein localization;   integral ER membrane protein positioning;   localization of protein in ER membrane;   positioning of protein in ER membrane;   protein insertion into endoplasmic reticulum membrane;   protein-ER insertion;   protein-endoplasmic reticulum insertion


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protein insertion into ER membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccdc47 coiled-coil domain containing 47 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:106,090,086...106,107,349
Ensembl chr11:106,088,234...106,107,170 		JBrowse link
G Get1 guided entry of tail-anchored proteins factor 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr16:95,946,600...95,959,052
Ensembl chr16:95,946,607...95,959,052 		JBrowse link
G Get4 golgi to ER traffic protein 4 involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 5:139,237,303...139,255,806
Ensembl chr 5:139,238,079...139,255,806 		JBrowse link
G Sec61a1 SEC61 translocon subunit alpha 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 6:88,480,589...88,495,782
Ensembl chr 6:88,480,561...88,495,887 		JBrowse link
G Tram1 translocating chain-associating membrane protein 1 involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 1:13,634,917...13,660,134
Ensembl chr 1:13,634,922...13,660,134 		JBrowse link
G Tram1l1 translocation associated membrane protein 1-like 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 3:124,114,686...124,116,909
Ensembl chr 3:124,114,504...124,118,392 		JBrowse link
G Tram2 translocating chain-associating membrane protein 2 involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 1:21,071,621...21,149,449
Ensembl chr 1:21,066,523...21,149,453 		JBrowse link
G Wdr83os WD repeat domain 83 opposite strand involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 8:85,807,592...85,808,968
Ensembl chr 8:85,807,369...85,808,968 		JBrowse link
multi-pass transmembrane protein insertion into ER membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccdc47 coiled-coil domain containing 47 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:106,090,086...106,107,349
Ensembl chr11:106,088,234...106,107,170 		JBrowse link
G Ncln nicalin involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr10:81,322,289...81,333,178
Ensembl chr10:81,322,083...81,332,226 		JBrowse link
G Nomo1 nodal modulator 1 involved_in ISO (PMID:36261522) UniProt PMID:36261522 NCBI chr 7:45,683,120...45,733,636
Ensembl chr 7:45,683,122...45,733,636 		JBrowse link
G Rab5if RAB5 interacting factor involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:156,705,042...156,715,483
Ensembl chr 2:156,705,048...156,715,483 		JBrowse link
G Tmco1 transmembrane and coiled-coil domains 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 1:167,136,239...167,161,547
Ensembl chr 1:167,135,947...167,161,547 		JBrowse link
G Tmem147 transmembrane protein 147 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:30,427,126...30,428,959
Ensembl chr 7:30,427,126...30,428,965 		JBrowse link
G Wdr83os WD repeat domain 83 opposite strand involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 8:85,807,592...85,808,968
Ensembl chr 8:85,807,369...85,808,968 		JBrowse link
protein insertion into ER membrane by stop-transfer membrane-anchor sequence term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Emc1 ER membrane protein complex subunit 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 4:139,079,898...139,106,046
Ensembl chr 4:139,079,898...139,106,041 		JBrowse link
G Emc10 ER membrane protein complex subunit 10 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:44,139,361...44,145,953
Ensembl chr 7:44,139,361...44,145,953 		JBrowse link
G Emc2 ER membrane protein complex subunit 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr15:43,340,603...43,391,174
Ensembl chr15:43,340,625...43,391,159 		JBrowse link
G Emc3 ER membrane protein complex subunit 3 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 6:113,491,848...113,508,599
Ensembl chr 6:113,491,835...113,508,613 		JBrowse link
G Emc4 ER membrane protein complex subunit 4 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:112,193,349...112,209,532
Ensembl chr 2:112,193,356...112,198,372 		JBrowse link
G Emc6 ER membrane protein complex subunit 6 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:73,066,329...73,067,868
Ensembl chr11:73,066,345...73,067,863 		JBrowse link
G Emc7 ER membrane protein complex subunit 7 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:112,285,332...112,302,507
Ensembl chr 2:112,285,342...112,302,507 		JBrowse link
G Emc8 ER membrane protein complex subunit 8 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 8:121,380,653...121,394,826
Ensembl chr 8:121,380,653...121,395,312 		JBrowse link
G Emc9 ER membrane protein complex subunit 9 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr14:55,818,976...55,822,832
Ensembl chr14:55,818,973...55,822,759 		JBrowse link
G Mmgt1 membrane magnesium transporter 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr  X:55,630,872...55,643,304
Ensembl chr  X:55,630,872...55,643,429 		JBrowse link
G Wnk1 WNK lysine deficient protein kinase 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 6:119,900,930...120,015,659
Ensembl chr 6:119,900,930...120,015,633 		JBrowse link
tail-anchored membrane protein insertion into ER membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag6 BCL2-associated athanogene 6 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr17:35,354,132...35,366,297
Ensembl chr17:35,354,154...35,366,298 		JBrowse link
G Caml calcium modulating ligand involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 NCBI chr13:55,770,818...55,780,229
Ensembl chr13:55,770,818...55,780,224 		JBrowse link
G Emc1 ER membrane protein complex subunit 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 4:139,079,898...139,106,046
Ensembl chr 4:139,079,898...139,106,041 		JBrowse link
G Emc10 ER membrane protein complex subunit 10 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:44,139,361...44,145,953
Ensembl chr 7:44,139,361...44,145,953 		JBrowse link
G Emc2 ER membrane protein complex subunit 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr15:43,340,603...43,391,174
Ensembl chr15:43,340,625...43,391,159 		JBrowse link
G Emc3 ER membrane protein complex subunit 3 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 6:113,491,848...113,508,599
Ensembl chr 6:113,491,835...113,508,613 		JBrowse link
G Emc4 ER membrane protein complex subunit 4 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:112,193,349...112,209,532
Ensembl chr 2:112,193,356...112,198,372 		JBrowse link
G Emc6 ER membrane protein complex subunit 6 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:73,066,329...73,067,868
Ensembl chr11:73,066,345...73,067,863 		JBrowse link
G Emc7 ER membrane protein complex subunit 7 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:112,285,332...112,302,507
Ensembl chr 2:112,285,342...112,302,507 		JBrowse link
G Emc8 ER membrane protein complex subunit 8 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 8:121,380,653...121,394,826
Ensembl chr 8:121,380,653...121,395,312 		JBrowse link
G Emc9 ER membrane protein complex subunit 9 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr14:55,818,976...55,822,832
Ensembl chr14:55,818,973...55,822,759 		JBrowse link
G Get1 guided entry of tail-anchored proteins factor 1 involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 NCBI chr16:95,946,600...95,959,052
Ensembl chr16:95,946,607...95,959,052 		JBrowse link
G Get3 guided entry of tail-anchored proteins factor 3, ATPase involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 NCBI chr 8:85,744,558...85,751,916
Ensembl chr 8:85,744,560...85,751,910 		JBrowse link
G Get4 golgi to ER traffic protein 4 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 5:139,237,303...139,255,806
Ensembl chr 5:139,238,079...139,255,806 		JBrowse link
G Mmgt1 membrane magnesium transporter 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr  X:55,630,872...55,643,304
Ensembl chr  X:55,630,872...55,643,429 		JBrowse link
G Sgta small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr10:80,879,905...80,896,105
Ensembl chr10:80,879,909...80,896,015 		JBrowse link
G Ubl4a ubiquitin-like 4A involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr  X:73,409,324...73,412,154
Ensembl chr  X:73,409,324...73,416,824 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28573
    cellular process 17545
      cellular component organization or biogenesis 6954
        cellular component organization 6731
          organelle organization 3699
            endoplasmic reticulum organization 99
              protein insertion into ER membrane 29
                multi-pass transmembrane protein insertion into ER membrane 7
                protein insertion into ER membrane by N-terminal cleaved signal sequence 0
                protein insertion into ER membrane by internal uncleaved signal-anchor sequence 0
                protein insertion into ER membrane by stop-transfer membrane-anchor sequence 11
                tail-anchored membrane protein insertion into ER membrane 17
Path 2
Term Annotations click to browse term
  biological_process 28573
    localization 5534
      cellular localization 3698
        cellular macromolecule localization 2742
          protein localization 2730
            protein localization to membrane 670
              establishment of protein localization to membrane 284
                protein insertion into membrane 46
                  protein insertion into ER membrane 29
                    multi-pass transmembrane protein insertion into ER membrane 7
                    protein insertion into ER membrane by N-terminal cleaved signal sequence 0
                    protein insertion into ER membrane by internal uncleaved signal-anchor sequence 0
                    protein insertion into ER membrane by stop-transfer membrane-anchor sequence 11
                    tail-anchored membrane protein insertion into ER membrane 17
paths to the root