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ONTOLOGY REPORT - ANNOTATIONS


Term:early endosome to late endosome transport
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Accession:GO:0045022 term browser browse the term
Definition:The directed movement of substances, in membrane-bounded vesicles, from the early sorting endosomes to the late sorting endosomes; transport occurs along microtubules and can be experimentally blocked with microtubule-depolymerizing drugs.


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early endosome to late endosome transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07026291.1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 Ensembl chr16:70,778,913...70,831,164 JBrowse link
G Aktip AKT interacting protein involved_in ISS
ISO
GO_REF:0000024
(PMID:18799622)
UniProt
RGD
PMID:18799622 GO_REF:0000024 NCBI chr19:17,290,048...17,300,054
Ensembl chr19:17,290,178...17,300,050
JBrowse link
G Ankrd27 ankyrin repeat domain 27 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(PMID:16525121)
RGD PMID:16525121, PMID:21873635 RGD:13792537 NCBI chr 1:91,857,048...91,958,763
Ensembl chr 1:91,857,057...91,958,763
JBrowse link
G Becn1 beclin 1 involved_in ISO
ISS
(PMID:26783301)
GO_REF:0000024
RGD
UniProt
PMID:26783301 GO_REF:0000024 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Emp2 epithelial membrane protein 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:5607239|PMID:18400107)
UniProt
RGD
PMID:18400107 GO_REF:0000024 MGI:5607239 NCBI chr10:5,433,248...5,467,840
Ensembl chr10:5,433,248...5,467,839
JBrowse link
G Fhip1b FHF complex subunit HOOK interacting protein 1B involved_in ISO
ISS
(PMID:18799622)
GO_REF:0000024
RGD
UniProt
PMID:18799622 GO_REF:0000024 NCBI chr 1:170,216,505...170,238,898
Ensembl chr 1:170,212,817...170,238,890
JBrowse link
G Flna filamin A acts_upstream_of_or_within ISO (MGI:1326769|PMID:9412467) RGD PMID:9412467 MGI:1326769 NCBI chr  X:156,460,785...156,487,245
Ensembl chr  X:156,463,953...156,487,245
JBrowse link
G Hap1 huntingtin-associated protein 1 TAS RGD PMID:12021262 RGD:625566 NCBI chr10:88,257,975...88,266,210
Ensembl chr10:88,257,976...88,266,210
JBrowse link
G Hook1 hook microtubule-tethering protein 1 involved_in ISO (PMID:18799622) RGD PMID:18799622 NCBI chr 5:114,940,053...115,000,691
Ensembl chr 5:114,940,053...115,000,691
JBrowse link
G Hook2 hook microtubule-tethering protein 2 involved_in ISO (PMID:18799622) RGD PMID:18799622 NCBI chr19:26,106,713...26,119,353
Ensembl chr19:26,106,838...26,119,352
JBrowse link
G Hook3 hook microtubule-tethering protein 3 involved_in ISO (PMID:18799622) RGD PMID:18799622 NCBI chr16:70,710,347...70,818,789 JBrowse link
G Kif16b kinesin family member 16B involved_in ISO (PMID:15882625) RGD PMID:15882625 NCBI chr 3:136,596,621...136,936,809
Ensembl chr 3:136,657,480...136,936,674
JBrowse link
G Lmtk2 lemur tyrosine kinase 2 involved_in ISO (PMID:18429820) RGD PMID:18429820 NCBI chr12:12,409,876...12,546,111
Ensembl chr12:12,409,876...12,546,111
JBrowse link
G Pik3c3 phosphatidylinositol 3-kinase, catalytic subunit type 3 involved_in ISS
ISO
GO_REF:0000024
(PMID:14617358)
UniProt
RGD
PMID:14617358 GO_REF:0000024 NCBI chr18:22,964,121...23,047,896
Ensembl chr18:22,964,210...23,047,895
JBrowse link
G Ptpn23 protein tyrosine phosphatase, non-receptor type 23 involved_in ISO
IEA
(PMID:24821423)
GO_REF:0000107
RGD
Ensembl
PMID:24821423 GO_REF:0000107 NCBI chr 8:118,628,777...118,651,238
Ensembl chr 8:118,628,777...118,651,238
JBrowse link
G Rab5a RAB5A, member RAS oncogene family involved_in ISO (PMID:17562788) RGD PMID:17562788 NCBI chr 9:5,910...6,065 JBrowse link
G Rab7a RAB7A, member RAS oncogene family involved_in ISO
ISS
(PMID:14617358)
GO_REF:0000024
(PMID:8522602)
RGD
UniProt
PMID:8522602 PMID:14617358 GO_REF:0000024 NCBI chr 4:119,910,461...119,963,065
Ensembl chr 4:119,910,478...119,959,173
JBrowse link
G Rilp Rab interacting lysosomal protein involved_in ISO
IBA
(PMID:17959629)
PMID:21873635
RGD PMID:17959629, PMID:21873635 RGD:13792537 NCBI chr10:63,658,451...63,662,428
Ensembl chr10:63,659,085...63,662,050
JBrowse link
G Snf8 SNF8 subunit of ESCRT-II involved_in ISO (PMID:17714434) RGD PMID:17714434 NCBI chr10:83,856,331...83,868,621
Ensembl chr10:83,856,280...83,868,598
JBrowse link
G Snx16 sorting nexin 16 involved_in IDA
IEA
IBA
ISO
GO_REF:0000107
PMID:21873635
(PMID:12813048)
Ensembl
RGD
PMID:12813048, PMID:12813048, PMID:21873635 GO_REF:0000107, RGD:737670, RGD:13792537 NCBI chr 2:93,518,796...93,541,056
Ensembl chr 2:93,518,806...93,540,328
JBrowse link
G Stx8 syntaxin 8 involved_in ISO (PMID:10564279) RGD PMID:10564279 NCBI chr10:54,512,922...54,753,302
Ensembl chr10:54,512,983...54,753,302
JBrowse link
G Wdr81 WD repeat domain 81 involved_in ISS
ISO
GO_REF:0000024
(PMID:26783301), (PMID:27126989)
UniProt
RGD
PMID:26783301 PMID:27126989 GO_REF:0000024 NCBI chr10:62,273,817...62,287,213
Ensembl chr10:62,273,800...62,287,189
JBrowse link
G Wdr91 WD repeat domain 91 involved_in ISO
ISS
IBA
(PMID:26783301), (PMID:27126989)
GO_REF:0000024
PMID:21873635
RGD
UniProt
PMID:26783301 PMID:27126989, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 4:62,398,073...62,438,958
Ensembl chr 4:62,398,797...62,438,958
JBrowse link
negative regulation of early endosome to late endosome transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Snx12 sorting nexin 12 involved_in ISO (PMID:22719997) RGD PMID:22719997 NCBI chr  X:70,989,822...71,127,330
Ensembl chr  X:70,989,822...71,127,278
JBrowse link
G Snx3 sorting nexin 3 involved_in ISO (PMID:18767904) RGD PMID:18767904 NCBI chr20:47,225,382...47,263,390
Ensembl chr20:47,225,619...47,263,390
JBrowse link
positive regulation of early endosome to late endosome transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dab2 DAB adaptor protein 2 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 2:55,747,353...55,768,848
Ensembl chr 2:55,747,318...55,768,270
JBrowse link
G Ezr ezrin involved_in ISO UniProtKB:P26038|UniProtKB:P35241 (PMID:21148287) RGD PMID:21148287 NCBI chr 1:47,287,872...47,331,412
Ensembl chr 1:47,287,874...47,331,412
JBrowse link
G Msn moesin involved_in ISO
IEA
UniProtKB:P15311|UniProtKB:P35241 (PMID:21148287)
GO_REF:0000107
RGD
Ensembl
PMID:21148287 GO_REF:0000107 NCBI chr  X:65,226,834...65,294,192
Ensembl chr  X:65,226,748...65,295,810
JBrowse link
G Mtmr2 myotubularin related protein 2 involved_in IMP PMID:20410104 BHF-UCL PMID:20410104 RGD:8553482 NCBI chr 8:12,283,471...12,334,014
Ensembl chr 8:12,284,528...12,333,316
JBrowse link
G Ptpn23 protein tyrosine phosphatase, non-receptor type 23 involved_in ISO
IEA
(PMID:21724833)
GO_REF:0000107
RGD
Ensembl
PMID:21724833 GO_REF:0000107 NCBI chr 8:118,628,777...118,651,238
Ensembl chr 8:118,628,777...118,651,238
JBrowse link
G Rab21 RAB21, member RAS oncogene family involved_in ISO (PMID:15561770) RGD PMID:15561770 NCBI chr 7:58,261,985...58,286,770
Ensembl chr 7:58,261,992...58,286,770
JBrowse link
G Rdx radixin involved_in ISO UniProtKB:P15311|UniProtKB:P26038 (PMID:21148287) RGD PMID:21148287 NCBI chr 8:56,570,728...56,612,851
Ensembl chr 8:56,585,396...56,610,612
JBrowse link
G Vps11 VPS11 core subunit of CORVET and HOPS complexes involved_in ISO (PMID:21148287) RGD PMID:21148287 NCBI chr 8:48,677,492...48,692,295
Ensembl chr 8:48,677,492...48,692,295
JBrowse link
regulation of early endosome to late endosome transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chmp3 charged multivesicular body protein 3 involved_in ISO (PMID:16554368) RGD PMID:16554368 NCBI chr 4:99,449,213...99,496,156
Ensembl chr 4:99,449,111...99,494,423
JBrowse link
G Dennd10 DENN domain containing 10 involved_in IBA
ISO
PMID:21873635
(PMID:30771381)
RGD PMID:30771381, PMID:21873635 RGD:13792537 NCBI chr 1:282,188,080...282,211,588
Ensembl chr 1:282,188,110...282,210,580
JBrowse link
G Dnajc13 DnaJ heat shock protein family (Hsp40) member C13 involved_in ISO (PMID:18256511) RGD PMID:18256511 NCBI chr 8:112,697,907...112,830,445
Ensembl chr 8:112,698,348...112,807,598
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 involved_in TAS PMID:19565474 UniProt PMID:19565474 RGD:8553538 NCBI chr 8:69,134,218...69,722,573
Ensembl chr 8:69,134,223...69,164,758
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 involved_in TAS PMID:19565474 UniProt PMID:19565474 RGD:8553538 NCBI chr 7:11,458,971...11,478,520
Ensembl chr 7:11,458,967...11,478,489
JBrowse link
G Mapk1 mitogen activated protein kinase 1 involved_in TAS PMID:19565474 UniProt PMID:19565474 RGD:8553538 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 involved_in TAS PMID:19565474 UniProt PMID:19565474 RGD:8553538 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Sh3glb1 SH3 domain -containing GRB2-like endophilin B1 IMP RGD PMID:18768694 RGD:13504749 NCBI chr 2:250,709,812...250,744,216
Ensembl chr 2:250,709,439...250,744,196
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO (PMID:21724833) RGD PMID:21724833 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19612
    cellular process 18457
      vesicle-mediated transport 1672
        vesicle-mediated transport between endosomal compartments 44
          early endosome to late endosome transport 41
            negative regulation of early endosome to late endosome transport 2
            positive regulation of early endosome to late endosome transport 8
            regulation of early endosome to late endosome transport + 19
Path 2
Term Annotations click to browse term
  biological_process 19612
    localization 6449
      establishment of localization 4865
        transport 4700
          intracellular transport 1507
            cytosolic transport 166
              early endosome to late endosome transport 41
                negative regulation of early endosome to late endosome transport 2
                positive regulation of early endosome to late endosome transport 8
                regulation of early endosome to late endosome transport + 19
paths to the root