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ONTOLOGY REPORT - ANNOTATIONS

Term:early endosome to late endosome transport
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Accession:GO:0045022 term browser browse the term
Definition:The directed movement of substances, in membrane-bounded vesicles, from the early sorting endosomes to the late sorting endosomes; transport occurs along microtubules and can be experimentally blocked with microtubule-depolymerizing drugs.


show annotations for term's descendants           Sort by:
early endosome to late endosome transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aktip AKT interacting protein involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:18799622)		 UniProt
Ensembl
RGD		 PMID:18799622 GO_REF:0000024 GO_REF:0000107 NCBI chr19:15,866,811...15,877,123
Ensembl chr19:15,866,928...15,886,663 		JBrowse link
G Ankrd27 ankyrin repeat domain 27 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(PMID:16525121)		 RGD PMID:16525121 PMID:21873635 RGD:13792537 NCBI chr 1:88,251,216...88,303,615
Ensembl chr 1:88,251,226...88,303,615 		JBrowse link
G Atg14 autophagy related 14 involved_in ISO (PMID:14617358) RGD PMID:14617358 NCBI chr15:20,795,750...20,827,113
Ensembl chr15:20,795,750...20,827,113 		JBrowse link
G Becn1 beclin 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:14617358), (PMID:26783301)		 UniProt
RGD		 PMID:14617358 PMID:26783301 GO_REF:0000024 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Emp2 epithelial membrane protein 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5607239|PMID:18400107)		 UniProt
RGD		 PMID:18400107 GO_REF:0000024 MGI:5607239 NCBI chr10:5,360,073...5,394,734
Ensembl chr10:5,360,073...5,394,733 		JBrowse link
G Fhip1b FHF complex subunit HOOK interacting protein 1B involved_in ISO
IEA
IBA
ISS		 (PMID:18799622)
GO_REF:0000107
PMID:21873635
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:18799622 PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr 1:159,718,679...159,748,449
Ensembl chr 1:159,726,004...159,748,408 		JBrowse link
G Flna filamin A acts_upstream_of_or_within ISO (MGI:1326769|PMID:9412467) RGD PMID:9412467 MGI:1326769 NCBI chr  X:152,007,758...152,034,266
Ensembl chr  X:152,007,758...152,031,052 		JBrowse link
G Hap1 huntingtin-associated protein 1 TAS RGD PMID:12021262 RGD:625566 NCBI chr10:85,277,890...85,286,126
Ensembl chr10:85,277,890...85,286,126 		JBrowse link
G Hook1 hook microtubule-tethering protein 1 involved_in ISO (PMID:18799622) RGD PMID:18799622 NCBI chr 5:110,824,501...110,887,791
Ensembl chr 5:110,824,501...110,887,787 		JBrowse link
G Hook2 hook microtubule-tethering protein 2 involved_in ISO (PMID:18799622) RGD PMID:18799622 NCBI chr19:23,151,869...23,170,139
Ensembl chr19:23,151,870...23,164,181 		JBrowse link
G Hook3 hook microtubule-tethering protein 3 involved_in ISO (PMID:18799622) RGD PMID:18799622 NCBI chr16:65,954,293...66,058,812
Ensembl chr16:65,954,350...66,061,338 		JBrowse link
G Kif16b kinesin family member 16B involved_in ISO (PMID:15882625) RGD PMID:15882625 NCBI chr 3:129,974,692...130,254,194
Ensembl chr 3:129,974,800...130,254,019 		JBrowse link
G Lmtk2 lemur tyrosine kinase 2 involved_in ISO (PMID:18429820) RGD PMID:18429820 NCBI chr12:10,426,772...10,508,750
Ensembl chr12:10,426,777...10,508,750 		JBrowse link
G Pik3c3 phosphatidylinositol 3-kinase, catalytic subunit type 3 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:14617358)		 UniProt
Ensembl
RGD		 PMID:14617358 GO_REF:0000024 GO_REF:0000107 NCBI chr18:21,845,282...21,934,387
Ensembl chr18:21,845,295...21,929,048 		JBrowse link
G Pik3r4 phosphoinositide-3-kinase, regulatory subunit 4 involved_in ISO (PMID:14617358) RGD PMID:14617358 NCBI chr 8:106,267,908...106,316,585
Ensembl chr 8:106,267,954...106,316,584 		JBrowse link
G Ptpn23 protein tyrosine phosphatase, non-receptor type 23 involved_in ISO
IBA
IEA		 (PMID:24821423)
PMID:21873635
GO_REF:0000107		 RGD
Ensembl		 PMID:24821423 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 8:110,360,804...110,383,271
Ensembl chr 8:110,360,804...110,383,271 		JBrowse link
G Pxk PX domain containing serine/threonine kinase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:16,759,857...16,828,452
Ensembl chr15:16,759,862...16,828,444 		JBrowse link
G Rab5a RAB5A, member RAS oncogene family involved_in ISO (PMID:17562788) RGD PMID:17562788 NCBI chr 9:6,483,906...6,512,877
Ensembl chr 9:6,484,469...6,512,873 		JBrowse link
G Rab7a RAB7A, member RAS oncogene family involved_in ISO
ISS		 (PMID:14617358)
GO_REF:0000024
(PMID:8522602)		 RGD
UniProt		 PMID:8522602 PMID:14617358 GO_REF:0000024 NCBI chr 4:120,461,966...120,510,756
Ensembl chr 4:120,461,963...120,506,889 		JBrowse link
G Rilp Rab interacting lysosomal protein involved_in ISO
IBA		 (PMID:17959629)
PMID:21873635		 RGD PMID:17959629 PMID:21873635 RGD:13792537 NCBI chr10:60,355,276...60,358,434
Ensembl chr10:60,355,278...60,358,781 		JBrowse link
G Snf8 SNF8 subunit of ESCRT-II involved_in ISO (PMID:17714434) RGD PMID:17714434 NCBI chr10:80,984,337...80,996,724
Ensembl chr10:80,984,363...80,996,734 		JBrowse link
G Snx16 sorting nexin 16 involved_in IDA
IEA
IBA
ISO		 GO_REF:0000107
PMID:21873635
(PMID:12813048)		 Ensembl
RGD		 PMID:12813048 PMID:12813048 PMID:21873635 GO_REF:0000107, RGD:737670, RGD:13792537 NCBI chr 2:91,335,896...91,357,622
Ensembl chr 2:91,336,092...91,357,619 		JBrowse link
G Stx8 syntaxin 8 involved_in ISO
IEA		 (PMID:10564279)
GO_REF:0000107		 RGD
Ensembl		 PMID:10564279 GO_REF:0000107 NCBI chr10:52,655,643...52,900,048
Ensembl chr10:52,654,990...52,894,993 		JBrowse link
G Wdr81 WD repeat domain 81 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:26783301), (PMID:27126989)		 UniProt
Ensembl
RGD		 PMID:26783301 PMID:27126989 GO_REF:0000024 GO_REF:0000107 NCBI chr10:60,281,969...60,295,374
Ensembl chr10:60,281,972...60,295,296 		JBrowse link
G Wdr91 WD repeat domain 91 involved_in ISO
ISS
IBA		 (PMID:26783301), (PMID:27126989)
GO_REF:0000024
PMID:21873635		 RGD
UniProt		 PMID:26783301 PMID:27126989 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 4:63,554,364...63,591,733
Ensembl chr 4:63,554,364...63,591,733 		JBrowse link
negative regulation of early endosome to late endosome transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Snx12 sorting nexin 12 involved_in ISO (PMID:22719997) RGD PMID:22719997 NCBI chr  X:66,226,995...66,356,945
Ensembl chr  X:66,227,053...66,356,950 		JBrowse link
G Snx3 sorting nexin 3 involved_in ISO (PMID:18767904) RGD PMID:18767904 NCBI chr20:45,992,446...46,025,361
Ensembl chr20:45,992,720...46,025,379 		JBrowse link
positive regulation of early endosome to late endosome transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dab2 DAB adaptor protein 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:21995445)		 Ensembl
RGD		 PMID:21995445 GO_REF:0000107 NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476 		JBrowse link
G Ezr ezrin involved_in ISO
IBA
IEA		 UniProtKB:P26038|UniProtKB:P35241 (PMID:21148287)
PMID:21873635
GO_REF:0000107		 RGD
Ensembl		 PMID:21148287 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505 		JBrowse link
G Msn moesin involved_in ISO
IBA
IEA		 UniProtKB:P15311|UniProtKB:P35241 (PMID:21148287)
PMID:21873635
GO_REF:0000107		 RGD
Ensembl		 PMID:21148287 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr  X:60,996,043...61,064,011
Ensembl chr  X:60,995,951...61,065,628 		JBrowse link
G Mtmr2 myotubularin related protein 2 involved_in IMP PMID:20410104 BHF-UCL PMID:20410104 RGD:8553482 NCBI chr 8:10,617,993...10,670,724
Ensembl chr 8:10,617,993...10,668,172 		JBrowse link
G Nf2 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:79,627,399...79,710,709
Ensembl chr14:79,627,399...79,710,667 		JBrowse link
G Ptpn23 protein tyrosine phosphatase, non-receptor type 23 involved_in ISO
IEA		 (PMID:21724833)
GO_REF:0000107		 RGD
Ensembl		 PMID:21724833 GO_REF:0000107 NCBI chr 8:110,360,804...110,383,271
Ensembl chr 8:110,360,804...110,383,271 		JBrowse link
G Rab21 RAB21, member RAS oncogene family involved_in ISO (PMID:15561770) RGD PMID:15561770 NCBI chr 7:50,904,050...50,928,890
Ensembl chr 7:50,904,057...50,928,839 		JBrowse link
G Rdx radixin involved_in ISO
IBA		 UniProtKB:P15311|UniProtKB:P26038 (PMID:21148287)
PMID:21873635		 RGD PMID:21148287 PMID:21873635 RGD:13792537 NCBI chr 8:52,379,494...52,437,673
Ensembl chr 8:52,379,494...52,437,678 		JBrowse link
G Vps11 VPS11 core subunit of CORVET and HOPS complexes involved_in ISO (PMID:21148287) RGD PMID:21148287 NCBI chr 8:44,683,768...44,698,572
Ensembl chr 8:44,684,127...44,698,568 		JBrowse link
regulation of early endosome to late endosome transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chmp3 charged multivesicular body protein 3 involved_in ISO (PMID:16554368) RGD PMID:16554368 NCBI chr 4:103,576,453...103,622,566
Ensembl chr 4:103,576,515...103,623,959 		JBrowse link
G Dennd10 DENN domain containing 10 involved_in IBA
ISO		 PMID:21873635
(PMID:30771381)		 RGD PMID:30771381 PMID:21873635 RGD:13792537 NCBI chr 1:259,950,928...259,974,456
Ensembl chr 1:259,950,866...259,974,455 		JBrowse link
G Dnajc13 DnaJ heat shock protein family (Hsp40) member C13 involved_in ISO (PMID:18256511) RGD PMID:18256511 NCBI chr 8:104,767,785...104,877,317
Ensembl chr 8:104,767,788...104,877,317 		JBrowse link
G ENSRNOG00000067941 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 Ensembl chr11:42,352,734...42,354,134 JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 involved_in TAS PMID:19565474 UniProt PMID:19565474 RGD:8553538 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147 		JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 involved_in TAS PMID:19565474 UniProt PMID:19565474 RGD:8553538 NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 involved_in TAS
IEA		 PMID:19565474
GO_REF:0000117		 UniProt PMID:19565474 GO_REF:0000117, RGD:8553538 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 involved_in TAS
IEA		 PMID:19565474
GO_REF:0000117		 UniProt PMID:19565474 GO_REF:0000117, RGD:8553538 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Sh3glb1 SH3 domain -containing GRB2-like endophilin B1 IMP RGD PMID:18768694 RGD:13504749 NCBI chr 2:233,750,838...233,784,817
Ensembl chr 2:233,750,838...233,784,784 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO (PMID:21724833) RGD PMID:21724833 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19818
    cellular process 17392
      cellular localization 3569
        intracellular transport 1632
          cytosolic transport 178
            early endosome to late endosome transport 45
              negative regulation of early endosome to late endosome transport 2
              positive regulation of early endosome to late endosome transport 9
              regulation of early endosome to late endosome transport + 21
Path 2
Term Annotations click to browse term
  biological_process 19818
    localization 5601
      establishment of localization 4940
        transport 4764
          intracellular transport 1632
            cytosolic transport 178
              early endosome to late endosome transport 45
                negative regulation of early endosome to late endosome transport 2
                positive regulation of early endosome to late endosome transport 9
                regulation of early endosome to late endosome transport + 21
paths to the root