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ONTOLOGY REPORT - ANNOTATIONS


Term:DNA methylation or demethylation
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Accession:GO:0044728 term browser browse the term
Definition:The process of adding or removing a methyl group from one or more nucleotides within an DNA molecule.
Synonyms:related_synonym: changes in DNA methylation


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C-5 methylation of cytosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNMT3B DNA methyltransferase 3 beta acts_upstream_of_or_within ISO (MGI:5811689|PMID:27856912) MGI PMID:27856912 MGI:5811689 NCBI chr24:22,096,386...22,123,378
Ensembl chr24:22,096,349...22,122,900
JBrowse link
G STPG4 sperm-tail PG-rich repeat containing 4 acts_upstream_of_or_within ISO (MGI:5762940|PMID:23560077) MGI PMID:23560077 MGI:5762940 NCBI chr10:49,255,715...49,294,752
Ensembl chr10:49,255,723...49,294,708
JBrowse link
DNA demethylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AICDA activation induced cytidine deaminase involved_in ISS UniProt GO_REF:0000024 NCBI chr27:37,064,107...37,073,791
Ensembl chr27:37,064,080...37,073,789
JBrowse link
G ALKBH1 alkB homolog 1, histone H2A dioxygenase involved_in ISO (PMID:18603530), (PMID:30017583), (PMID:30392959) UniProt PMID:18603530 PMID:30017583 PMID:30392959 NCBI chr 8:50,444,994...50,471,151
Ensembl chr 8:50,445,748...50,471,135
JBrowse link
G ALKBH4 alkB homolog 4, lysine demethylase involved_in ISO (MGI:6323482|PMID:30982744) UniProt PMID:30982744 MGI:6323482 NCBI chr 6:7,717,240...7,723,364
Ensembl chr 6:7,717,282...7,723,048
JBrowse link
G APEX1 apurinic/apyrimidinic endodeoxyribonuclease 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:17,786,808...17,789,422
Ensembl chr15:17,786,357...17,789,422
JBrowse link
G APOBEC1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr27:37,102,728...37,114,084
Ensembl chr27:37,103,016...37,114,556
JBrowse link
G APOBEC2 apolipoprotein B mRNA editing enzyme catalytic subunit 2 involved_in ISO (PMID:21496894) UniProt PMID:21496894 NCBI chr12:9,808,276...9,819,973
Ensembl chr12:9,808,297...9,819,985
JBrowse link
G APOBEC3Z1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3Z1 involved_in ISO (PMID:21496894) UniProt PMID:21496894
G APOBEC3Z3 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3Z3 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr10:25,910,973...25,917,508
Ensembl chr10:25,911,291...25,913,808
JBrowse link
G FTO FTO alpha-ketoglutarate dependent dioxygenase involved_in ISO (PMID:18775698)
(MGI:3817348|PMID:18775698), (MGI:4430814|PMID:17991826)
BHF-UCL PMID:17991826 PMID:18775698 MGI:3817348 MGI:4430814 NCBI chr 2:61,699,864...62,080,199
Ensembl chr 2:61,652,236...62,080,059
JBrowse link
G TDG thymine DNA glycosylase involved_in ISO (MGI:5287540|PMID:21817016)
(MGI:5141157|PMID:21722948), (MGI:5487523|PMID:21278727)
UniProt PMID:21278727 PMID:21722948 PMID:21817016 MGI:5141157 MGI:5287540 MGI:5487523 NCBI chr15:42,493,593...42,516,868
Ensembl chr15:42,493,737...42,515,448
JBrowse link
G TET1 tet methylcytosine dioxygenase 1 acts_upstream_of_or_within
involved_in
ISO (MGI:4822076|PMID:20639862)
(MGI:3844762|PMID:19372391), (MGI:5285126|PMID:21496894)
(PMID:21496894)
MGI
UniProt
PMID:19372391 PMID:20639862 PMID:21496894 MGI:3844762 MGI:4822076 MGI:5285126 NCBI chr 4:19,759,661...19,898,345
Ensembl chr 4:19,768,137...19,889,907
JBrowse link
G TET2 tet methylcytosine dioxygenase 2 involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:4822076|PMID:20639862)
GO_Central
MGI
PMID:20639862 PMID:21873635 MGI:4822076 NCBI chr32:26,021,745...26,145,109
Ensembl chr32:26,059,693...26,143,536
JBrowse link
G TET3 tet methylcytosine dioxygenase 3 involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:4822076|PMID:20639862), (MGI:5525037|PMID:23690950)
GO_Central
MGI
PMID:20639862 PMID:21873635 PMID:23690950 MGI:4822076 MGI:5525037 NCBI chr17:48,976,510...49,083,454
Ensembl chr17:48,981,558...49,082,675
JBrowse link
DNA demethylation of male pronucleus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G STPG4 sperm-tail PG-rich repeat containing 4 involved_in ISO (MGI:5762940|PMID:23560077) UniProt PMID:23560077 MGI:5762940 NCBI chr10:49,255,715...49,294,752
Ensembl chr10:49,255,723...49,294,708
JBrowse link
G TET3 tet methylcytosine dioxygenase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:48,976,510...49,083,454
Ensembl chr17:48,981,558...49,082,675
JBrowse link
DNA hypermethylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNMT1 DNA methyltransferase 1 ISO RGD PMID:21682946 RGD:9588311 NCBI chr20:50,872,213...50,928,352
Ensembl chr20:50,879,527...50,928,029
JBrowse link
G MORC1 MORC family CW-type zinc finger 1 acts_upstream_of_or_within ISO (MGI:5694015|PMID:25503965) MGI PMID:25503965 MGI:5694015 NCBI chr33:14,120,370...14,302,995
Ensembl chr33:14,147,504...14,291,024
JBrowse link
DNA methylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF7IP activating transcription factor 7 interacting protein involved_in ISO (PMID:12665582) UniProt PMID:12665582 NCBI chr27:32,082,615...32,194,954
Ensembl chr27:32,086,675...32,177,364
JBrowse link
G BAZ2A bromodomain adjacent to zinc finger domain 2A involved_in ISO (MGI:3587127|PMID:16085498), (MGI:3852588|PMID:19578370) UniProt PMID:16085498 PMID:19578370 MGI:3587127 MGI:3852588 NCBI chr10:834,018...868,817
Ensembl chr10:836,465...863,874
JBrowse link
G BEND3 BEN domain containing 3 involved_in ISO (PMID:26100909) UniProt PMID:26100909 NCBI chr12:64,302,403...64,324,396
Ensembl chr12:64,306,140...64,322,725
JBrowse link
G BMI1 BMI1 proto-oncogene, polycomb ring finger acts_upstream_of_or_within ISO (MGI:5522578|PMID:24105743) MGI PMID:24105743 MGI:5522578 NCBI chr 2:10,818,232...10,828,473
Ensembl chr 2:10,818,232...10,833,613
JBrowse link
G CTCF CCCTC-binding factor acts_upstream_of_or_within ISO (MGI:5522578|PMID:24105743)
(MGI:2450195|PMID:12461525)
MGI PMID:12461525 PMID:24105743 MGI:2450195 MGI:5522578 NCBI chr 5:81,808,512...81,863,811
Ensembl chr 5:81,809,393...81,858,655
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 ISO RGD PMID:29115507 RGD:25823175 NCBI chr30:37,793,277...37,799,535
Ensembl chr30:37,793,508...37,796,866
JBrowse link
G DNMT1 DNA methyltransferase 1 acts_upstream_of_or_within ISO (MGI:2152690|PMID:11399088)
(MGI:5522578|PMID:24105743), (MGI:5888829|PMID:27892467)
(MGI:6151717|PMID:27841881)
(MGI:3655888|PMID:16887828)
MGI PMID:11399088 PMID:16887828 PMID:24105743 PMID:27841881 PMID:27892467 MGI:2152690 MGI:3655888 MGI:5522578 MGI:5888829 MGI:6151717 NCBI chr20:50,872,213...50,928,352
Ensembl chr20:50,879,527...50,928,029
JBrowse link
G DNMT3A DNA methyltransferase 3 alpha acts_upstream_of_or_within
involved_in
ISO (MGI:3768461|PMID:17938196)
(MGI:6151717|PMID:27841881)
(PMID:30478443)
(PMID:12138111), (PMID:19786833), (PMID:23042785)
(MGI:2152692|PMID:11399089), (MGI:2178074|PMID:11934864)
MGI
UniProt
PMID:11399089 PMID:11934864 PMID:12138111 PMID:17938196 PMID:19786833 More... MGI:2152692 MGI:2178074 MGI:3768461 MGI:6151717 NCBI chr17:19,489,524...19,563,074
Ensembl chr17:19,492,193...19,563,902
JBrowse link
G DNMT3B DNA methyltransferase 3 beta acts_upstream_of_or_within ISO (MGI:3623538|PMID:16543361)
(MGI:6151717|PMID:27841881)
(MGI:5320860|PMID:22133874)
(MGI:3768461|PMID:17938196)
MGI PMID:16543361 PMID:17938196 PMID:22133874 PMID:27841881 MGI:3623538 MGI:3768461 MGI:5320860 MGI:6151717 NCBI chr24:22,096,386...22,123,378
Ensembl chr24:22,096,349...22,122,900
JBrowse link
G DNMT3L DNA methyltransferase 3 like acts_upstream_of_or_within ISO (MGI:5694015|PMID:25503965) MGI PMID:25503965 MGI:5694015 NCBI chr31:38,099,100...38,111,432 JBrowse link
G EHMT1 euchromatic histone lysine methyltransferase 1 involved_in ISO (MGI:3826717|PMID:18818694) UniProt PMID:18818694 MGI:3826717 NCBI chr 9:48,031,593...48,110,954
Ensembl chr 9:48,032,709...48,175,828
JBrowse link
G EHMT2 euchromatic histone lysine methyltransferase 2 involved_in ISO (MGI:3826717|PMID:18818694) UniProt PMID:18818694 MGI:3826717 NCBI chr12:1,341,202...1,354,602
Ensembl chr12:1,341,191...1,354,584
JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit acts_upstream_of_or_within ISO (MGI:5522578|PMID:24105743) MGI PMID:24105743 MGI:5522578 NCBI chr16:1,926,443...1,991,995
Ensembl chr16:1,925,956...1,991,838
JBrowse link
G GNAS GNAS complex locus acts_upstream_of_or_within ISO (MGI:4454202|PMID:20427744) MGI PMID:20427744 MGI:4454202 NCBI chr24:43,643,409...43,658,641
Ensembl chr24:43,643,405...43,658,657
JBrowse link
G HELLS helicase, lymphoid specific acts_upstream_of_or_within ISO (MGI:2153312|PMID:11711429) MGI PMID:11711429 MGI:2153312 NCBI chr28:8,660,866...8,705,570
Ensembl chr28:8,661,008...8,705,580
JBrowse link
G KMT2A lysine methyltransferase 2A acts_upstream_of_or_within ISO (MGI:3625774|PMID:16618927) MGI PMID:16618927 MGI:3625774 NCBI chr 5:15,212,559...15,302,825
Ensembl chr 5:15,217,348...15,270,971
JBrowse link
G KMT2E lysine methyltransferase 2E (inactive) involved_in ISO (MGI:3834766|PMID:18854576) UniProt PMID:18854576 MGI:3834766 NCBI chr18:15,240,631...15,332,850
Ensembl chr18:15,239,994...15,332,828
JBrowse link
G MTA2 metastasis associated 1 family member 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:4888087|PMID:20720167) Ensembl
MGI
PMID:20720167 GO_REF:0000107 MGI:4888087 NCBI chr18:54,038,073...54,046,376
Ensembl chr18:54,038,212...54,046,059
JBrowse link
G MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase involved_in ISO (MGI:5512657|PMID:24074862) UniProt PMID:24074862 MGI:5512657 NCBI chr34:6,068,572...6,119,580
Ensembl chr34:6,070,046...6,098,312
JBrowse link
G PPM1D protein phosphatase, Mg2+/Mn2+ dependent 1D involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:35,856,277...35,914,096
Ensembl chr 9:35,856,765...35,913,884
JBrowse link
G SPOCD1 SPOC domain containing 1 involved_in ISO (MGI:6453929|PMID:32674113) UniProt PMID:32674113 MGI:6453929 NCBI chr 2:69,254,343...69,326,588
Ensembl chr 2:69,289,328...69,326,595
JBrowse link
G TEX15 testis expressed 15, meiosis and synapsis associated involved_in ISO (MGI:6434559|PMID:32381626), (MGI:6447460|PMID:32719317) UniProt PMID:32381626 PMID:32719317 MGI:6434559 MGI:6447460 NCBI chr16:33,423,546...33,517,458
Ensembl chr16:33,423,876...33,515,452
JBrowse link
DNA methylation involved in embryo development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNMT1 DNA methyltransferase 1 acts_upstream_of_or_within_positive_effect ISO (MGI:6270117|PMID:29117290)
(MGI:6151717|PMID:27841881)
(MGI:49689|PMID:1606615)
MGI PMID:1606615 PMID:27841881 PMID:29117290 MGI:49689 MGI:6151717 MGI:6270117 NCBI chr20:50,872,213...50,928,352
Ensembl chr20:50,879,527...50,928,029
JBrowse link
G DNMT3A DNA methyltransferase 3 alpha acts_upstream_of_or_within
involved_in
ISO (MGI:1347183|PMID:10555141)
(MGI:6151717|PMID:27841881)
(MGI:3045942|PMID:15215868)
(MGI:5014027|PMID:20385583)
MGI
UniProt
PMID:10555141 PMID:15215868 PMID:20385583 PMID:27841881 MGI:1347183 MGI:3045942 MGI:5014027 MGI:6151717 NCBI chr17:19,489,524...19,563,074
Ensembl chr17:19,492,193...19,563,902
JBrowse link
G DNMT3B DNA methyltransferase 3 beta acts_upstream_of_or_within ISO (MGI:1347183|PMID:10555141)
(MGI:6151717|PMID:27841881)
(PMID:18814855)
MGI
UniProt
PMID:10555141 PMID:18814855 PMID:27841881 MGI:1347183 MGI:6151717 NCBI chr24:22,096,386...22,123,378
Ensembl chr24:22,096,349...22,122,900
JBrowse link
G TRIM28 tripartite motif containing 28 acts_upstream_of_or_within ISO (MGI:5319411|PMID:22495301) MGI PMID:22495301 MGI:5319411 NCBI chr 1:99,408,920...99,415,432
Ensembl chr 1:99,408,925...99,415,146
JBrowse link
G ZDBF2 zinc finger DBF-type containing 2 acts_upstream_of_or_within ISO (MGI:6151717|PMID:27841881) MGI PMID:27841881 MGI:6151717 NCBI chr37:14,867,344...14,897,552
Ensembl chr37:14,871,575...14,894,047
JBrowse link
G ZFP57 ZFP57 zinc finger protein involved_in
acts_upstream_of_or_within
ISO (PMID:18622393)
(MGI:6506156|PMID:33500348)
(MGI:3826319|PMID:18854139)
UniProt
MGI
PMID:18622393 PMID:18854139 PMID:33500348 MGI:3826319 MGI:6506156 NCBI chr35:26,267,358...26,269,429 JBrowse link
DNA methylation involved in gamete generation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASZ1 ankyrin repeat, SAM and basic leucine zipper domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:56,197,784...56,250,067
Ensembl chr14:56,197,875...56,250,073
JBrowse link
G CTCFL CCCTC-binding factor like involved_in ISO (MGI:3692841|PMID:17048991) UniProt PMID:17048991 MGI:3692841 NCBI chr24:42,477,029...42,507,217
Ensembl chr24:42,477,342...42,507,225
JBrowse link
G DDX4 DEAD-box helicase 4 involved_in ISO (MGI:4443217|PMID:20439430) UniProt PMID:20439430 MGI:4443217 NCBI chr 2:43,026,367...43,109,546
Ensembl chr 2:43,027,296...43,109,526
JBrowse link
G DNMT3A DNA methyltransferase 3 alpha involved_in ISO (MGI:3045942|PMID:15215868) UniProt PMID:15215868 MGI:3045942 NCBI chr17:19,489,524...19,563,074
Ensembl chr17:19,492,193...19,563,902
JBrowse link
G DNMT3L DNA methyltransferase 3 like involved_in ISO (MGI:3054275|PMID:15318244) UniProt PMID:15318244 MGI:3054275 NCBI chr31:38,099,100...38,111,432 JBrowse link
G FKBP6 FKBP prolyl isomerase family member 6 (inactive) involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:6,836,043...6,868,268
Ensembl chr 6:6,836,086...6,868,818
JBrowse link
G KDM1B lysine demethylase 1B acts_upstream_of_or_within ISO (MGI:4358629|PMID:19727073) MGI PMID:19727073 MGI:4358629 NCBI chr35:16,954,483...17,014,261
Ensembl chr35:16,921,095...17,012,527
JBrowse link
G MAEL maelstrom spermatogenic transposon silencer involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:31,364,111...31,394,675
Ensembl chr 7:31,364,293...31,409,435
JBrowse link
G MORC1 MORC family CW-type zinc finger 1 acts_upstream_of_or_within ISO (MGI:5694015|PMID:25503965) MGI PMID:25503965 MGI:5694015 NCBI chr33:14,120,370...14,302,995
Ensembl chr33:14,147,504...14,291,024
JBrowse link
G MOV10L1 Mov10 like RISC complex RNA helicase 1 involved_in ISO (MGI:4457283|PMID:20534472) UniProt PMID:20534472 MGI:4457283 NCBI chr10:17,067,273...17,139,910
Ensembl chr10:17,067,273...17,240,197
JBrowse link
G PIWIL2 piwi like RNA-mediated gene silencing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:34,911,120...34,987,287
Ensembl chr25:34,912,358...34,987,339
JBrowse link
G PIWIL4 piwi like RNA-mediated gene silencing 4 involved_in ISO (MGI:3778312|PMID:18381894), (MGI:3815367|PMID:18922463) UniProt PMID:18381894 PMID:18922463 MGI:3778312 MGI:3815367 NCBI chr21:6,319,986...6,391,149
Ensembl chr21:6,319,987...6,366,787
JBrowse link
G PLD6 phospholipase D family member 6 involved_in ISS UniProt GO_REF:0000024 NCBI chr 5:42,208,594...42,212,403
Ensembl chr 5:42,208,609...42,210,796
JBrowse link
G PRMT7 protein arginine methyltransferase 7 involved_in ISO (MGI:3692841|PMID:17048991) UniProt PMID:17048991 MGI:3692841 NCBI chr 5:81,172,085...81,216,708
Ensembl chr 5:81,173,147...81,216,669
JBrowse link
G TDRD1 tudor domain containing 1 involved_in ISO (MGI:4356231|PMID:19465913) UniProt PMID:19465913 MGI:4356231 NCBI chr28:25,028,195...25,081,300
Ensembl chr28:25,028,317...25,081,170
JBrowse link
G TDRD12 tudor domain containing 12 involved_in ISO (MGI:5516419|PMID:24067652) UniProt PMID:24067652 MGI:5516419 NCBI chr 1:119,229,721...119,290,101
Ensembl chr 1:119,231,485...119,290,086
JBrowse link
G TDRD5 tudor domain containing 5 involved_in ISS UniProt GO_REF:0000024 NCBI chr 7:20,259,940...20,348,014
Ensembl chr 7:20,261,630...20,348,650
JBrowse link
G TDRD9 tudor domain containing 9 involved_in ISO (MGI:4418580|PMID:20059948) UniProt PMID:20059948 MGI:4418580 NCBI chr 8:71,610,653...71,717,772
Ensembl chr 8:71,610,711...71,717,199
JBrowse link
G TDRKH tudor and KH domain containing involved_in ISO (MGI:5494327|PMID:23714778) UniProt PMID:23714778 MGI:5494327 NCBI chr17:60,794,937...60,807,852
Ensembl chr17:60,795,813...60,805,449
JBrowse link
DNA methylation on adenine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G METTL4 methyltransferase 4, N6-adenosine involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:69,229,717...69,268,223
Ensembl chr 7:69,191,223...69,267,683
JBrowse link
G N6AMT1 N-6 adenine-specific DNA methyltransferase 1 NOT|involved_in ISO (PMID:30392959), (PMID:31632689), (PMID:31636962)
(PMID:30017583)
UniProt PMID:30017583 PMID:30392959 PMID:31632689 PMID:31636962 NCBI chr31:23,895,558...23,934,183
Ensembl chr31:23,895,584...23,909,940
JBrowse link
DNA methylation on cytosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNMT1 DNA methyltransferase 1 acts_upstream_of_or_within ISO (MGI:49689|PMID:1606615) RGD
MGI
PMID:1606615 PMID:22880885 MGI:49689 RGD:9588218 NCBI chr20:50,872,213...50,928,352
Ensembl chr20:50,879,527...50,928,029
JBrowse link
G DNMT3A DNA methyltransferase 3 alpha ISO RGD PMID:22880885 RGD:9588218 NCBI chr17:19,489,524...19,563,074
Ensembl chr17:19,492,193...19,563,902
JBrowse link
G DNMT3L DNA methyltransferase 3 like involved_in ISO (MGI:3054275|PMID:15318244) UniProt PMID:15318244 MGI:3054275 NCBI chr31:38,099,100...38,111,432 JBrowse link
DNA methylation on cytosine within a CG sequence term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNMT1 DNA methyltransferase 1 ISO RGD PMID:3856245 RGD:2301219 NCBI chr20:50,872,213...50,928,352
Ensembl chr20:50,879,527...50,928,029
JBrowse link
G EHMT2 euchromatic histone lysine methyltransferase 2 acts_upstream_of_or_within ISO (MGI:3718157|PMID:17212651) MGI PMID:17212651 MGI:3718157 NCBI chr12:1,341,202...1,354,602
Ensembl chr12:1,341,191...1,354,584
JBrowse link
G SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 acts_upstream_of_or_within ISO (MGI:3610843|PMID:16287714) MGI PMID:16287714 MGI:3610843 NCBI chr20:50,175,489...50,268,865
Ensembl chr20:50,175,687...50,268,836
JBrowse link
hypermethylation of CpG island term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNMT3A DNA methyltransferase 3 alpha involved_in ISO (MGI:5009774|PMID:21047779) BHF-UCL PMID:21047779 MGI:5009774 NCBI chr17:19,489,524...19,563,074
Ensembl chr17:19,492,193...19,563,902
JBrowse link
G GSK3A glycogen synthase kinase 3 alpha involved_in ISO (MGI:5009774|PMID:21047779) BHF-UCL PMID:21047779 MGI:5009774 NCBI chr 1:112,129,116...112,138,714
Ensembl chr 1:112,103,825...112,138,559
JBrowse link
G GSK3B glycogen synthase kinase 3 beta involved_in ISO (MGI:5009774|PMID:21047779) BHF-UCL PMID:21047779 MGI:5009774 NCBI chr33:23,458,369...23,659,878
Ensembl chr33:23,463,767...23,659,666
JBrowse link
G SPI1 Spi-1 proto-oncogene involved_in ISO (PMID:20139074) UniProt PMID:20139074 NCBI chr18:42,253,849...42,269,497
Ensembl chr18:42,253,811...42,269,727
JBrowse link
hypomethylation of CpG island term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr34:12,600,140...12,681,905
Ensembl chr34:12,600,233...12,675,910
JBrowse link
G ZMPSTE24 zinc metallopeptidase STE24 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5607719|PMID:20961378) Ensembl
MGI
PMID:20961378 GO_REF:0000107 MGI:5607719 NCBI chr15:2,669,546...2,708,480
Ensembl chr15:2,670,326...2,709,160
JBrowse link
negative regulation of DNA demethylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DPPA3 developmental pluripotency associated 3 involved_in ISO (MGI:5432962|PMID:22722204), (MGI:5447615|PMID:17143267), (MGI:5465527|PMID:21407207) UniProt PMID:17143267 PMID:21407207 PMID:22722204 MGI:5432962 MGI:5447615 MGI:5465527 NCBI chr27:37,114,192...37,196,434 JBrowse link
G GATA3 GATA binding protein 3 acts_upstream_of_or_within ISO (MGI:3046385|PMID:15087456) MGI PMID:15087456 MGI:3046385 NCBI chr 2:28,068,143...28,098,445
Ensembl chr 2:28,069,051...28,087,760
JBrowse link
G TRIM28 tripartite motif containing 28 acts_upstream_of_or_within ISO (MGI:5319411|PMID:22495301) MGI PMID:22495301 MGI:5319411 NCBI chr 1:99,408,920...99,415,432
Ensembl chr 1:99,408,925...99,415,146
JBrowse link
negative regulation of DNA methylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNMT3L DNA methyltransferase 3 like involved_in ISO (MGI:5553039|PMID:24074865) UniProt PMID:24074865 MGI:5553039 NCBI chr31:38,099,100...38,111,432 JBrowse link
G KMT2A lysine methyltransferase 2A involved_in ISO (PMID:20010842) UniProt PMID:20010842 NCBI chr 5:15,212,559...15,302,825
Ensembl chr 5:15,217,348...15,270,971
JBrowse link
oxidative DNA demethylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALKBH2 alkB homolog 2, alpha-ketoglutarate dependent dioxygenase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr26:17,911,892...17,918,911
Ensembl chr26:17,911,763...17,917,788
JBrowse link
oxidative single-stranded DNA demethylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALKBH1 alkB homolog 1, histone H2A dioxygenase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 8:50,444,994...50,471,151
Ensembl chr 8:50,445,748...50,471,135
JBrowse link
G ALKBH3 alkB homolog 3, alpha-ketoglutarate dependent dioxygenase involved_in ISO (PMID:22055184)
(PMID:16858410)
UniProt PMID:16858410 PMID:22055184 NCBI chr18:25,864,041...25,899,226
Ensembl chr18:25,824,877...25,899,079
JBrowse link
G FTO FTO alpha-ketoglutarate dependent dioxygenase involved_in IEA InterPro GO_REF:0000002 NCBI chr 2:61,699,864...62,080,199
Ensembl chr 2:61,652,236...62,080,059
JBrowse link
positive regulation of DNA demethylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G OTUD4 OTU deubiquitinase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:43,816,656...43,861,813
Ensembl chr15:43,818,196...43,861,784
JBrowse link
G STPG4 sperm-tail PG-rich repeat containing 4 involved_in ISO (MGI:5762940|PMID:23560077) UniProt PMID:23560077 MGI:5762940 NCBI chr10:49,255,715...49,294,752
Ensembl chr10:49,255,723...49,294,708
JBrowse link
G TOX thymocyte selection associated high mobility group box involved_in IEA Ensembl GO_REF:0000107 NCBI chr29:9,542,471...9,841,759
Ensembl chr29:9,544,561...9,842,034
JBrowse link
G USP7 ubiquitin specific peptidase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:33,277,328...33,315,601
Ensembl chr 6:33,277,444...33,314,491
JBrowse link
G USP9X ubiquitin specific peptidase 9 X-linked involved_in ISO (PMID:25944111) UniProt PMID:25944111 NCBI chr  X:35,522,873...35,676,086 JBrowse link
positive regulation of DNA methylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNMT3L DNA methyltransferase 3 like involved_in ISO (MGI:5553039|PMID:24074865) UniProt PMID:24074865 MGI:5553039 NCBI chr31:38,099,100...38,111,432 JBrowse link
G MECP2 methyl-CpG binding protein 2 involved_in ISO (PMID:23960241) BHF-UCL PMID:23960241 NCBI chr  X:121,866,721...121,876,088
Ensembl chr  X:121,873,218...121,932,994
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor involved_in ISO (PMID:19786833) BHF-UCL PMID:19786833 NCBI chr13:25,200,772...25,205,309
Ensembl chr13:25,200,577...25,205,309
JBrowse link
G WT1 WT1 transcription factor acts_upstream_of ISO (PMID:23042785) ARUK-UCL PMID:23042785 NCBI chr18:35,099,660...35,148,767
Ensembl chr18:35,103,934...35,148,000
JBrowse link
protection of DNA demethylation of female pronucleus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DPPA3 developmental pluripotency associated 3 involved_in ISO (MGI:5432962|PMID:22722204), (MGI:5447615|PMID:17143267), (MGI:5465527|PMID:21407207) UniProt PMID:17143267 PMID:21407207 PMID:22722204 MGI:5432962 MGI:5447615 MGI:5465527 NCBI chr27:37,114,192...37,196,434 JBrowse link
regulation of DNA methylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BRCA1 BRCA1 DNA repair associated involved_in ISO (MGI:5009779|PMID:20820192) BHF-UCL PMID:20820192 MGI:5009779 NCBI chr 9:19,958,941...20,025,494
Ensembl chr 9:19,958,391...20,025,494
JBrowse link
G EHMT2 euchromatic histone lysine methyltransferase 2 ISO RGD PMID:22880885 RGD:9588218 NCBI chr12:1,341,202...1,354,602
Ensembl chr12:1,341,191...1,354,584
JBrowse link
G GRHL2 grainyhead like transcription factor 2 involved_in ISO (PMID:23254293)
(PMID:20938050)
UniProt PMID:20938050 PMID:23254293 NCBI chr13:3,204,898...3,362,533
Ensembl chr13:3,204,925...3,362,096
JBrowse link
G H1-8 H1.8 linker histone involved_in ISO (MGI:5559660|PMID:22868987) UniProt PMID:22868987 MGI:5559660 NCBI chr20:5,614,822...5,619,136
Ensembl chr20:5,617,001...5,624,352
JBrowse link
G KDM1B lysine demethylase 1B involved_in ISO (MGI:4358629|PMID:19727073) UniProt PMID:19727073 MGI:4358629 NCBI chr35:16,954,483...17,014,261
Ensembl chr35:16,921,095...17,012,527
JBrowse link
G MBD1 methyl-CpG binding domain protein 1 ISO RGD PMID:20735989 RGD:9588647 NCBI chr 7:78,597,688...78,611,303
Ensembl chr 7:78,597,746...78,651,472
JBrowse link
G MBD2 methyl-CpG binding domain protein 2 ISO RGD PMID:20735989 RGD:9588647 NCBI chr 1:21,232,260...21,283,687
Ensembl chr 1:21,235,967...21,283,346
JBrowse link
G MBD3 methyl-CpG binding domain protein 3 ISO RGD PMID:20735989 RGD:9588647 NCBI chr20:57,296,713...57,312,988
Ensembl chr20:57,296,713...57,307,110
JBrowse link
G MECP2 methyl-CpG binding protein 2 ISO RGD PMID:20735989 RGD:9588647 NCBI chr  X:121,866,721...121,876,088
Ensembl chr  X:121,873,218...121,932,994
JBrowse link
G MIS18A MIS18 kinetochore protein A acts_upstream_of_or_within ISO (MGI:5438906|PMID:22516971) MGI PMID:22516971 MGI:5438906 NCBI chr31:27,025,657...27,039,001
Ensembl chr31:27,025,709...27,039,028
JBrowse link
G MPHOSPH8 M-phase phosphoprotein 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:18,392,706...18,443,241
Ensembl chr25:18,392,409...18,443,241
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 ISO RGD PMID:23260200 RGD:10413908 NCBI chr 7:38,503,072...38,542,556
Ensembl chr 7:38,503,067...38,542,127
JBrowse link
G PRDM14 PR/SET domain 14 acts_upstream_of_or_within ISO (MGI:5506832|PMID:23670199) MGI PMID:23670199 MGI:5506832 NCBI chr29:19,203,798...19,220,149
Ensembl chr29:19,203,807...19,220,518
JBrowse link
G PRMT5 protein arginine methyltransferase 5 ISO RGD PMID:22041901 RGD:9491827 NCBI chr 8:3,248,349...3,257,567
Ensembl chr 8:3,248,404...3,257,456
JBrowse link
G RLF RLF zinc finger involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5693990|PMID:25857663) Ensembl
MGI
PMID:25857663 GO_REF:0000107 MGI:5693990 NCBI chr15:2,723,511...2,815,305
Ensembl chr15:2,723,272...2,815,540
JBrowse link
G TET1 tet methylcytosine dioxygenase 1 acts_upstream_of_or_within ISO (MGI:4939073|PMID:21295276) MGI PMID:21295276 MGI:4939073 NCBI chr 4:19,759,661...19,898,345
Ensembl chr 4:19,768,137...19,889,907
JBrowse link
G ZMPSTE24 zinc metallopeptidase STE24 acts_upstream_of_or_within ISO (MGI:5607719|PMID:20961378) MGI PMID:20961378 MGI:5607719 NCBI chr15:2,669,546...2,708,480
Ensembl chr15:2,670,326...2,709,160
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 13863
    metabolic process 8966
      organic substance metabolic process 8614
        macromolecule metabolic process 7431
          macromolecule modification 3184
            DNA modification 98
              DNA methylation or demethylation 87
                DNA demethylation + 23
                DNA methylation + 69
                changes to DNA methylation involved in embryo development + 9
Path 2
Term Annotations click to browse term
  biological_process 13863
    metabolic process 8966
      cellular metabolic process 8165
        cellular nitrogen compound metabolic process 4854
          nucleobase-containing compound metabolic process 4193
            nucleic acid metabolic process 3834
              DNA metabolic process 737
                DNA modification 98
                  DNA methylation or demethylation 87
                    DNA demethylation + 23
                    DNA methylation + 69
                    changes to DNA methylation involved in embryo development + 9
paths to the root