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ONTOLOGY REPORT - ANNOTATIONS


Term:long-chain fatty acid import into cell
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Accession:GO:0044539 term browser browse the term
Definition:The directed movement of a long-chain fatty acid from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.
Comment:While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).
Synonyms:exact_synonym: long-chain fatty acid uptake
 related_synonym: long-chain fatty acid import


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long-chain fatty acid import into cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl1 acyl-CoA synthetase long chain family member 1 involved_in ISO (PMID:22022213)
PMID:23024797
UniProt
ARUK-UCL
PMID:22022213 PMID:23024797 RGD:39458021 NCBI chrNW_004955403:24,190,674...24,235,354
Ensembl chrNW_004955403:24,190,674...24,236,780
JBrowse link
G Acsl3 acyl-CoA synthetase long chain family member 3 acts_upstream_of ISO (PMID:20219900) UniProt PMID:20219900 NCBI chrNW_004955453:10,916,423...10,963,986
Ensembl chrNW_004955453:10,913,786...10,947,963
JBrowse link
G Cd36 CD36 molecule (CD36 blood group) involved_in ISO (PMID:17416590), (PMID:22022213)
(MGI:3718873|PMID:17507371)
UniProt PMID:17416590 PMID:17507371 PMID:22022213 MGI:3718873 NCBI chrNW_004955410:5,003,720...5,120,903
Ensembl chrNW_004955410:5,003,668...5,075,313
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 involved_in ISO (MGI:5913528|PMID:28178239) UniProt PMID:28178239 MGI:5913528 NCBI chrNW_004955451:3,181,085...3,225,610 JBrowse link
G Slc27a1 solute carrier family 27 member 1 involved_in ISO (PMID:28178239)
(MGI:6232786|PMID:23024797)
(MGI:6154651|PMID:12235169), (MGI:69386|PMID:7954810)
UniProt
ARUK-UCL
PMID:7954810 PMID:12235169 PMID:23024797 PMID:28178239 MGI:6154651 MGI:6232786 MGI:69386 NCBI chrNW_004955524:803,793...821,920
Ensembl chrNW_004955524:805,014...821,838
JBrowse link
G Slc27a2 solute carrier family 27 member 2 acts_upstream_of ISO (PMID:22022213) UniProt PMID:22022213 NCBI chrNW_004955409:4,077,685...4,112,828
Ensembl chrNW_004955409:4,077,149...4,112,828
JBrowse link
G Slc27a4 solute carrier family 27 member 4 involved_in ISO (PMID:22022213)
(MGI:6232786|PMID:23024797)
(MGI:5314874|PMID:21750264), (MGI:5703705|PMID:24503477)
UniProt
ARUK-UCL
PMID:21750264 PMID:22022213 PMID:23024797 PMID:24503477 MGI:5314874 MGI:5703705 MGI:6232786 NCBI chrNW_004955570:853,856...866,383
Ensembl chrNW_004955570:853,849...866,383
JBrowse link
G Spx spexin hormone involved_in ISO PMID:24550067
(MGI:5574430|PMID:24550067)
UniProt PMID:24550067 MGI:5574430 RGD:8693351 NCBI chrNW_004955413:17,173,215...17,178,388
Ensembl chrNW_004955413:17,173,215...17,178,388
JBrowse link
long-chain fatty acid import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) ISO leukotriene LTC4 transport RGD PMID:12867490 RGD:2303048 NCBI chrNW_004955442:729,322...858,826
Ensembl chrNW_004955442:729,316...860,290
JBrowse link
G Cd36 CD36 molecule (CD36 blood group) involved_in ISO (PMID:24503477) ARUK-UCL PMID:24503477 NCBI chrNW_004955410:5,003,720...5,120,903
Ensembl chrNW_004955410:5,003,668...5,075,313
JBrowse link
G Slc27a1 solute carrier family 27 member 1 involved_in ISO (PMID:28035674) ARUK-UCL PMID:28035674 NCBI chrNW_004955524:803,793...821,920
Ensembl chrNW_004955524:805,014...821,838
JBrowse link
G Slc27a5 solute carrier family 27 member 5 acts_upstream_of_or_within ISO (MGI:3722951|PMID:16618416) MGI PMID:16618416 MGI:3722951 NCBI chrNW_004955584:1,112,387...1,121,500
Ensembl chrNW_004955584:1,112,117...1,121,323
JBrowse link
G Slc2a1 solute carrier family 2 member 1 involved_in ISO (PMID:10227690) ARUK-UCL PMID:10227690 NCBI chrNW_004955537:2,408,042...2,438,788
Ensembl chrNW_004955537:2,408,042...2,439,511
JBrowse link
negative regulation of long-chain fatty acid import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 involved_in ISO (PMID:16814735) BHF-UCL PMID:16814735 NCBI chrNW_004955538:3,208,711...3,224,386
Ensembl chrNW_004955538:3,208,710...3,229,904
JBrowse link
G Akt2 AKT serine/threonine kinase 2 involved_in ISO (PMID:16814735) BHF-UCL PMID:16814735 NCBI chrNW_004955578:950,258...1,004,438
Ensembl chrNW_004955578:967,593...1,004,438
JBrowse link
G Irs2 insulin receptor substrate 2 involved_in ISO (PMID:16814735) BHF-UCL PMID:16814735 NCBI chrNW_004955404:2,531,484...2,555,383
Ensembl chrNW_004955404:2,531,484...2,555,689
JBrowse link
G Thbs1 thrombospondin 1 involved_in ISO (PMID:17416590) BHF-UCL PMID:17416590 NCBI chrNW_004955416:6,490,034...6,506,419
Ensembl chrNW_004955416:6,489,451...6,506,419
JBrowse link
positive regulation of long-chain fatty acid import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl1 acyl-CoA synthetase long chain family member 1 involved_in ISO PMID:24503477 ARUK-UCL PMID:24503477 RGD:39458020 NCBI chrNW_004955403:24,190,674...24,235,354
Ensembl chrNW_004955403:24,190,674...24,236,780
JBrowse link
G Acsl5 acyl-CoA synthetase long chain family member 5 ISO RGD PMID:16263710 RGD:2312807 NCBI chrNW_004955431:17,477,113...17,524,539
Ensembl chrNW_004955431:17,477,086...17,524,539
JBrowse link
G Acsl6 acyl-CoA synthetase long chain family member 6 ISO RGD PMID:15655248 RGD:2312811 NCBI chrNW_004955408:3,336,214...3,391,117
Ensembl chrNW_004955408:3,333,392...3,392,141
JBrowse link
positive regulation of long-chain fatty acid import into cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fabp3 fatty acid binding protein 3 involved_in ISO (MGI:3575839|PMID:15835924)
(MGI:1336545|PMID:10224224)
ARUK-UCL PMID:10224224 PMID:15835924 MGI:1336545 MGI:3575839 NCBI chrNW_004955452:9,851,182...9,858,735
Ensembl chrNW_004955452:9,846,689...9,861,971
JBrowse link
regulation of long-chain fatty acid import into cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eprs1 glutamyl-prolyl-tRNA synthetase 1 involved_in ISO (PMID:28178239)
(MGI:5913528|PMID:28178239)
UniProt PMID:28178239 MGI:5913528 NCBI chrNW_004955520:3,550,558...3,606,015
Ensembl chrNW_004955520:3,550,558...3,606,697
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12307
    localization 4245
      establishment of localization 3576
        transport 3303
          import into cell 725
            long-chain fatty acid import into cell 19
              long-chain fatty acid import across plasma membrane + 12
              negative regulation of long-chain fatty acid import into cell + 4
              positive regulation of long-chain fatty acid import into cell + 4
              regulation of long-chain fatty acid import into cell + 9
Path 2
Term Annotations click to browse term
  biological_process 12307
    localization 4245
      establishment of localization 3576
        transport 3303
          organic substance transport 1654
            organic acid transport 307
              carboxylic acid transport 305
                monocarboxylic acid transport 136
                  fatty acid transport 92
                    long-chain fatty acid transport 54
                      long-chain fatty acid import into cell 19
                        long-chain fatty acid import across plasma membrane + 12
                        negative regulation of long-chain fatty acid import into cell + 4
                        positive regulation of long-chain fatty acid import into cell + 4
                        regulation of long-chain fatty acid import into cell + 9
paths to the root