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ONTOLOGY REPORT - ANNOTATIONS


Term:long-chain fatty acid import into cell
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Accession:GO:0044539 term browser browse the term
Definition:The directed movement of a long-chain fatty acid from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.
Comment:While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).
Synonyms:exact_synonym: long-chain fatty acid uptake
 related_synonym: long-chain fatty acid import



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long-chain fatty acid import into cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl1 acyl-CoA synthetase long-chain family member 1 involved_in ISO
IMP
(PMID:22022213)
PMID:23024797
RGD PMID:22022213 PMID:23024797 RGD:39458021 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 acts_upstream_of
involved_in
ISO
IEA
(PMID:20219900)
GO_REF:0000107
RGD
Ensembl
PMID:20219900 GO_REF:0000107 NCBI chr 9:80,115,164...80,164,636
Ensembl chr 9:80,115,112...80,164,627
JBrowse link
G Cd36 CD36 molecule involved_in ISO
ISS
IBA
(PMID:17416590), (PMID:22022213)
GO_REF:0000024
(MGI:3718873|PMID:17507371)
GO_REF:0000033
RGD
UniProt
GO_Central
PMID:17416590 PMID:17507371 PMID:22022213 GO_REF:0000024 GO_REF:0000033 MGI:3718873 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
JBrowse link
G Cd36l1 CD36 molecule like 1 involved_in ISS
IBA
GO_REF:0000024
GO_REF:0000033
UniProt
GO_Central
GO_REF:0000024 GO_REF:0000033 NCBI chr 4:17,424,749...17,465,808
Ensembl chr 4:17,354,466...17,513,903
JBrowse link
G LOC134486712 platelet glycoprotein 4-like involved_in ISS
IBA
GO_REF:0000024
GO_REF:0000033
UniProt
GO_Central
GO_REF:0000024 GO_REF:0000033
G Rps6kb1 ribosomal protein S6 kinase B1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5913528|PMID:28178239)
UniProt
RGD
PMID:28178239 GO_REF:0000024 MGI:5913528 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
JBrowse link
G Slc27a1 solute carrier family 27 member 1 involved_in ISO
IBA
ISS
(PMID:28178239)
GO_REF:0000033
(MGI:6154651|PMID:12235169), (MGI:6232786|PMID:23024797), (MGI:69386|PMID:7954810)
GO_REF:0000024
RGD
GO_Central
UniProt
PMID:7954810 PMID:12235169 PMID:23024797 PMID:28178239 GO_REF:0000024 GO_REF:0000033 MGI:6154651 MGI:6232786 MGI:69386 NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063
JBrowse link
G Slc27a2 solute carrier family 27 member 2 involved_in
acts_upstream_of
IEA
IBA
ISO
GO_REF:0000107
GO_REF:0000033
(PMID:22022213)
Ensembl
GO_Central
RGD
PMID:22022213 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:113,804,728...113,842,208
Ensembl chr 3:113,804,728...113,842,208
JBrowse link
G Slc27a4 solute carrier family 27 member 4 involved_in ISO
IBA
(PMID:22022213)
GO_REF:0000033
(MGI:5314874|PMID:21750264), (MGI:5703705|PMID:24503477), (MGI:6232786|PMID:23024797)
RGD
GO_Central
PMID:21750264 PMID:22022213 PMID:23024797 PMID:24503477 GO_REF:0000033 MGI:5314874 MGI:5703705 MGI:6232786 NCBI chr 3:13,075,022...13,087,943
Ensembl chr 3:13,075,022...13,087,943
JBrowse link
G Slc27a5 solute carrier family 27 member 5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:73,616,556...73,627,149
Ensembl chr 1:73,616,564...73,627,172
JBrowse link
G Slc27a6 solute carrier family 27 member 6 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr18:52,040,241...52,099,622
Ensembl chr18:52,041,074...52,099,414
JBrowse link
G Spx spexin hormone involved_in IDA
ISO
PMID:24550067
(MGI:5574430|PMID:24550067)
RGD PMID:24550067 PMID:24550067 MGI:5574430, RGD:8693351 NCBI chr 4:175,356,044...175,362,082
Ensembl chr 4:175,356,247...175,362,082
JBrowse link
long-chain fatty acid import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 IDA leukotriene LTC4 transport RGD PMID:12867490 RGD:2303048 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Cd36 CD36 molecule involved_in ISO
IEA
(PMID:24503477)
GO_REF:0000107
RGD
Ensembl
PMID:24503477 GO_REF:0000107 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
JBrowse link
G Slc27a1 solute carrier family 27 member 1 involved_in ISO
IEA
(PMID:28035674)
GO_REF:0000107
RGD
Ensembl
PMID:28035674 GO_REF:0000107 NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063
JBrowse link
G Slc27a5 solute carrier family 27 member 5 acts_upstream_of_or_within ISO MGI:3757682 (PMID:16618416) RGD PMID:16618416 NCBI chr 1:73,616,556...73,627,149
Ensembl chr 1:73,616,564...73,627,172
JBrowse link
G Slc2a1 solute carrier family 2 member 1 involved_in ISO (PMID:10227690) RGD PMID:10227690 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
JBrowse link
negative regulation of long-chain fatty acid import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 involved_in ISO
IEA
(PMID:16814735)
GO_REF:0000107
RGD
Ensembl
PMID:16814735 GO_REF:0000107 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Akt2 AKT serine/threonine kinase 2 involved_in ISO
IEA
(PMID:16814735)
GO_REF:0000107
RGD
Ensembl
PMID:16814735 GO_REF:0000107 NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817
JBrowse link
G Irs2 insulin receptor substrate 2 involved_in ISO (PMID:16814735) RGD PMID:16814735 NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482
JBrowse link
G Thbs1 thrombospondin 1 involved_in ISO (PMID:17416590) RGD PMID:17416590 NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440
JBrowse link
positive regulation of long-chain fatty acid import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl1 acyl-CoA synthetase long-chain family member 1 involved_in IDA PMID:24503477 ARUK-UCL PMID:24503477 RGD:39458020 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 involved_in IDA
IBA
GO_REF:0000033 GO_Central
RGD
PMID:16263710 GO_REF:0000033, RGD:2312807 NCBI chr 1:254,289,513...254,336,608
Ensembl chr 1:254,292,521...254,336,607
JBrowse link
G Acsl6 acyl-CoA synthetase long-chain family member 6 IMP RGD PMID:15655248 RGD:2312811 NCBI chr10:38,439,914...38,501,182
Ensembl chr10:38,440,080...38,498,757
JBrowse link
positive regulation of long-chain fatty acid import into cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fabp3 fatty acid binding protein 3 involved_in ISO
IEA
(MGI:1336545|PMID:10224224), (MGI:3575839|PMID:15835924)
GO_REF:0000107
RGD
Ensembl
PMID:10224224 PMID:15835924 GO_REF:0000107 MGI:1336545 MGI:3575839 NCBI chr 5:142,651,962...142,658,707
Ensembl chr 5:142,651,956...142,658,718
JBrowse link
regulation of long-chain fatty acid import into cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eprs1 glutamyl-prolyl-tRNA synthetase 1 involved_in ISO (PMID:28178239)
(MGI:5913528|PMID:28178239)
RGD PMID:28178239 MGI:5913528 NCBI chr13:96,901,548...96,971,966
Ensembl chr13:96,901,575...96,971,966
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19872
    localization 5633
      establishment of localization 4939
        transport 4625
          import into cell 969
            long-chain fatty acid import into cell 22
              long-chain fatty acid import across plasma membrane + 12
              negative regulation of long-chain fatty acid import into cell + 4
              positive regulation of long-chain fatty acid import into cell + 4
              regulation of long-chain fatty acid import into cell + 9
Path 2
Term Annotations click to browse term
  biological_process 19872
    localization 5633
      establishment of localization 4939
        transport 4625
          organic acid transport 394
            carboxylic acid transport 392
              monocarboxylic acid transport 201
                fatty acid transport 131
                  long-chain fatty acid transport 75
                    long-chain fatty acid import into cell 22
                      long-chain fatty acid import across plasma membrane + 12
                      negative regulation of long-chain fatty acid import into cell + 4
                      positive regulation of long-chain fatty acid import into cell + 4
                      regulation of long-chain fatty acid import into cell + 9
paths to the root