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ONTOLOGY REPORT - ANNOTATIONS


Term:macropinocytosis
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Accession:GO:0044351 term browser browse the term
Definition:An endocytosis process that results in the uptake of liquid material by cells from their external environment by the 'ruffling' of the cell membrane to form heterogeneously sized intracellular vesicles called macropinosomes, which can be up to 5 micrometers in size.
Synonyms:broad_synonym: clathrin-independent pinocytosis
 related_synonym: single-organism macropinocytosis
 alt_id: GO:1902538



show annotations for term's descendants           Sort by:
macropinocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Carmil1 capping protein regulator and myosin 1 linker 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr13:24,196,464...24,464,983
Ensembl chr13:24,196,327...24,464,778
JBrowse link
G Dnm2 dynamin 2 involved_in ISO RGD
MGI
PMID:18003703 GO_REF:0000096 MGI:4417868 RGD:9685165 NCBI chr 9:21,336,167...21,419,055
Ensembl chr 9:21,336,204...21,419,055
JBrowse link
G Dock2 dedicator of cyto-kinesis 2 involved_in IMP (MGI:5291858|PMID:21892172) UniProt PMID:21892172 MGI:5291858 NCBI chr11:34,176,815...34,674,732
Ensembl chr11:34,176,815...34,674,719
JBrowse link
G Mapkapk2 MAP kinase-activated protein kinase 2 involved_in IMP (MGI:3761050|PMID:17906627) UniProt PMID:17906627 MGI:3761050 NCBI chr 1:130,981,437...131,025,580
Ensembl chr 1:130,981,437...131,025,563
JBrowse link
G Mapkapk3 mitogen-activated protein kinase-activated protein kinase 3 involved_in IMP (MGI:3761050|PMID:17906627) UniProt PMID:17906627 MGI:3761050 NCBI chr 9:107,132,125...107,167,082
Ensembl chr 9:107,132,126...107,167,076
JBrowse link
G Pycard PYD and CARD domain containing involved_in IMP (MGI:5291858|PMID:21892172) UniProt PMID:21892172 MGI:5291858 NCBI chr 7:127,590,545...127,593,039
Ensembl chr 7:127,588,880...127,593,039
JBrowse link
G Rab34 RAB34, member RAS oncogene family NOT|involved_in ISO (PMID:17881736) UniProt PMID:17881736 NCBI chr11:78,079,253...78,083,019
Ensembl chr11:78,079,256...78,083,019
JBrowse link
G Snx33 sorting nexin 33 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 9:56,824,472...56,835,726
Ensembl chr 9:56,824,477...56,835,655
JBrowse link
positive regulation of macropinocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Appl1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 involved_in IMP (MGI:6270783|PMID:27219021) UniProt PMID:27219021 MGI:6270783 NCBI chr14:26,640,943...26,692,567
Ensembl chr14:26,640,945...26,693,189
JBrowse link
G Appl2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 involved_in IMP (MGI:6270783|PMID:27219021) UniProt PMID:27219021 MGI:6270783 NCBI chr10:83,435,897...83,484,741
Ensembl chr10:83,435,897...83,484,602
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28573
    cellular process 17593
      vesicle-mediated transport 1624
        endocytosis 754
          pinocytosis 23
            macropinocytosis 10
              extracellular exosome macropinocytosis 0
              negative regulation of macropinocytosis 0
              positive regulation of macropinocytosis 2
              regulation of macropinocytosis + 2
Path 2
Term Annotations click to browse term
  biological_process 28573
    localization 5524
      establishment of localization 4823
        transport 4507
          vesicle-mediated transport 1624
            endocytosis 754
              pinocytosis 23
                macropinocytosis 10
                  extracellular exosome macropinocytosis 0
                  negative regulation of macropinocytosis 0
                  positive regulation of macropinocytosis 2
                  regulation of macropinocytosis + 2
paths to the root