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ONTOLOGY REPORT - ANNOTATIONS


Term:canonical Wnt signaling pathway involved in regulation of cell proliferation
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Accession:GO:0044340 term browser browse the term
Definition:The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to modulating the rate or frequency of cell proliferation.
Synonyms:exact_synonym: canonical Wnt receptor signaling pathway involved in regulation of cell proliferation;   canonical Wnt receptor signalling pathway involved in regulation of cell proliferation;   canonical Wnt-activated signaling pathway involved in regulation of cell proliferation


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canonical Wnt signaling pathway involved in regulation of cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dvl2 dishevelled segment polarity protein 2 involved_in ISO (PMID:18787224) RGD PMID:18787224 NCBI chr10:54,723,356...54,732,823
Ensembl chr10:54,723,411...54,732,820
JBrowse link
canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctnnb1 catenin beta 1 involved_in IEA
ISO
GO_REF:0000107
(MGI:2446944|PMID:12464179)
Ensembl
RGD
PMID:12464179 GO_REF:0000107 MGI:2446944 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Lrp6 LDL receptor related protein 6 acts_upstream_of_or_within ISO MGI:2156191 (MGI:4413394|PMID:19705442) RGD PMID:19705442 MGI:4413394 NCBI chr 4:167,266,581...167,400,155
Ensembl chr 4:167,270,353...167,400,497
JBrowse link
canonical Wnt signaling pathway involved in stem cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt3 Wnt family member 3 involved_in ISO
IEA
(PMID:25640183)
GO_REF:0000107
RGD
Ensembl
PMID:25640183 GO_REF:0000107 NCBI chr10:88,680,248...88,724,170
Ensembl chr10:88,680,248...88,724,099
JBrowse link
negative regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sfrp1 secreted frizzled-related protein 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:17994217)
Ensembl
RGD
PMID:17994217 GO_REF:0000107 NCBI chr16:68,575,763...68,613,905
Ensembl chr16:68,575,763...68,614,286
JBrowse link
positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt3a Wnt family member 3A involved_in ISO (MGI:4835142|PMID:17994217) RGD PMID:17994217 MGI:4835142 NCBI chr10:44,034,174...44,078,463
Ensembl chr10:44,034,194...44,078,324
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19494
    cellular process 18342
      cell population proliferation 2156
        canonical Wnt signaling pathway involved in regulation of cell proliferation 6
          canonical Wnt signaling pathway involved in positive regulation of cardiac muscle cell proliferation 0
          canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation 2
          canonical Wnt signaling pathway involved in positive regulation of secondary heart field cardioblast proliferation 0
          canonical Wnt signaling pathway involved in regulation of type B pancreatic cell proliferation + 2
          canonical Wnt signaling pathway involved in stem cell proliferation 1
Path 2
Term Annotations click to browse term
  biological_process 19494
    biological regulation 13507
      regulation of biological process 12763
        regulation of cellular process 12223
          signal transduction 6883
            cell surface receptor signaling pathway 2780
              cell surface receptor signaling pathway involved in cell-cell signaling 563
                Wnt signaling pathway 437
                  canonical Wnt signaling pathway 301
                    canonical Wnt signaling pathway involved in regulation of cell proliferation 6
                      canonical Wnt signaling pathway involved in positive regulation of cardiac muscle cell proliferation 0
                      canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation 2
                      canonical Wnt signaling pathway involved in positive regulation of secondary heart field cardioblast proliferation 0
                      canonical Wnt signaling pathway involved in regulation of type B pancreatic cell proliferation + 2
                      canonical Wnt signaling pathway involved in stem cell proliferation 1
paths to the root