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ONTOLOGY REPORT - ANNOTATIONS

Term:endoplasmic reticulum quality control compartment
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Accession:GO:0044322 term browser browse the term
Definition:A subcompartment of the endoplasmic reticulum in which proteins with improper or incorrect folding accumulate. Enzymes in this compartment direct proteins with major folding problems to translocation to the cytosol and degradation, and proteins with minor folding problems to the ER, to interact with chaperon proteins.
Synonyms:exact_synonym: ER quality control compartment;   ERQC
 related_synonym: ER-derived quality control compartment


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endoplasmic reticulum quality control compartment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asgr2 asialoglycoprotein receptor 2 located_in ISO (PMID:11408579) RGD PMID:11408579 NCBI chr10:54,821,407...54,834,624
Ensembl chr10:54,821,438...54,834,617 		JBrowse link
G Calr calreticulin located_in ISO (MGI:6120598|PMID:11408579) RGD PMID:11408579 MGI:6120598 NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414 		JBrowse link
G Canx calnexin located_in ISO (MGI:6120598|PMID:11408579) RGD PMID:11408579 MGI:6120598 NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821 		JBrowse link
G Derl1 derlin 1 located_in ISO (MGI:6467686|PMID:23233672) RGD PMID:23233672 MGI:6467686 NCBI chr 7:89,404,413...89,427,095
Ensembl chr 7:89,404,417...89,427,145 		JBrowse link
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 located_in ISO (PMID:23233672) RGD PMID:23233672 NCBI chr 4:141,797,631...141,829,717
Ensembl chr 4:141,797,701...141,829,717 		JBrowse link
G Edem2 ER degradation enhancing alpha-mannosidase like protein 2 located_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 3:144,201,604...144,227,423
Ensembl chr 3:144,201,605...144,227,485 		JBrowse link
G Edem3 ER degradation enhancing alpha-mannosidase like protein 3 located_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr13:63,858,282...63,920,538
Ensembl chr13:63,858,716...63,920,523 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 located_in ISO (MGI:6467680|PMID:17707796) RGD PMID:17707796 MGI:6467680 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Ern2 endoplasmic reticulum to nucleus signaling 2 located_in ISO (MGI:6467680|PMID:17707796) RGD PMID:17707796 MGI:6467680 NCBI chr 1:176,726,454...176,743,289
Ensembl chr 1:176,726,454...176,743,289 		JBrowse link
G Fbxo6 F-box protein 6 located_in
is_active_in		 ISO
IBA		 (MGI:5644019|PMID:21062743), (MGI:6467686|PMID:23233672)
PMID:21873635		 RGD PMID:21062743 PMID:23233672 PMID:21873635 MGI:5644019 MGI:6467686, RGD:13792537 NCBI chr 5:158,576,729...158,582,520
Ensembl chr 5:158,576,759...158,582,525 		JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 located_in ISO (MGI:6467687|PMID:24478453) RGD PMID:24478453 MGI:6467687 NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424 		JBrowse link
G Man1b1 mannosidase, alpha, class 1B, member 1 located_in ISO (PMID:18003979) RGD PMID:18003979 NCBI chr 3:8,143,877...8,165,007
Ensembl chr 3:8,143,381...8,165,006 		JBrowse link
G Rhbdd1 rhomboid domain containing 1 located_in ISS
ISO		 GO_REF:0000024
(MGI:5437551|PMID:22795130)		 UniProt
RGD		 PMID:22795130 GO_REF:0000024 MGI:5437551 NCBI chr 9:83,630,037...83,748,690
Ensembl chr 9:83,630,063...83,748,689 		JBrowse link
G Sec61b SEC61 translocon subunit beta located_in ISO (PMID:17707796)
(MGI:6120598|PMID:11408579), (MGI:6467680|PMID:17707796)		 RGD PMID:11408579 PMID:17707796 MGI:6120598 MGI:6467680 NCBI chr 5:61,773,594...61,781,804
Ensembl chr 5:61,773,594...61,781,804 		JBrowse link
G Syvn1 synoviolin 1 located_in ISO (PMID:23233672), (PMID:24478453)
(MGI:6467680|PMID:17707796)		 RGD PMID:17707796 PMID:23233672 PMID:24478453 MGI:6467680 NCBI chr 1:203,339,235...203,346,137
Ensembl chr 1:203,339,619...203,346,152 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20082
    cellular anatomical entity 19921
      endoplasmic reticulum quality control compartment 15
Path 2
Term Annotations click to browse term
  cellular_component 20082
    cellular anatomical entity 19921
      organelle 13177
        membrane-bounded organelle 11690
          intracellular membrane-bounded organelle 11180
            endoplasmic reticulum 1748
              endoplasmic reticulum quality control compartment 15
paths to the root