This term is obsolete.
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Definition:
OBSOLETE. The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.
Comment:
This term was obsoleted because it is not different from its parent, macromolecule metabolic process ; GO:0043170.