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ONTOLOGY REPORT - ANNOTATIONS

Term:organelle membrane contact site
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Accession:GO:0044232 term browser browse the term
Definition:A zone of apposition between the membranes of an organelle with another membrane, either another membrane of the same organelle, a membrane of another organelle, or the plasma membrane. Membrane contact sites (MCSs) are structured by bridging complexes. They are specialized for communication, including the efficient traffic of small molecules such as Ca2+ ions and lipids, as well as enzyme-substrate interactions.
Synonyms:exact_synonym: MCS
 narrow_synonym: inter-organelle junction;   interorganelle junction


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organelle membrane contact site term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATG2A autophagy related 2A is_active_in
located_in		 ISO
IEA		 (PMID:30952800) UniProt
Ensembl		 PMID:30952800 GO_REF:0000107 NCBI chr18:52,258,070...52,277,953
Ensembl chr18:52,258,187...52,277,965 		JBrowse link
G CLSTN3 calsyntenin 3 is_active_in ISO (MGI:7444870|PMID:36477540) UniProt PMID:36477540 MGI:7444870 NCBI chr27:37,879,047...37,913,317
Ensembl chr27:37,879,269...37,913,281 		JBrowse link
G ESYT2 extended synaptotagmin 2 located_in ISO (PMID:23791178) UniProt PMID:23791178 NCBI chr16:20,719,115...20,802,991
Ensembl chr16:20,718,499...20,811,468 		JBrowse link
G ESYT3 extended synaptotagmin 3 located_in IEA Ensembl GO_REF:0000107 NCBI chr23:34,645,248...34,692,178
Ensembl chr23:34,645,087...34,691,939 		JBrowse link
G GRAMD1A GRAM domain containing 1A located_in IEA Ensembl
UniProt		 GO_REF:0000107 GO_REF:0000117 NCBI chr 1:117,515,381...117,537,906
Ensembl chr 1:117,515,393...117,537,943 		JBrowse link
G GRAMD1B GRAM domain containing 1B located_in IEA UniProt GO_REF:0000117 NCBI chr 5:10,809,493...10,982,266
Ensembl chr 5:10,814,512...10,976,833 		JBrowse link
G GRAMD1C GRAM domain containing 1C located_in IEA UniProt GO_REF:0000117 NCBI chr33:18,132,860...18,214,363
Ensembl chr33:18,132,862...18,212,894 		JBrowse link
G GRAMD2A GRAM domain containing 2A located_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr30:35,679,571...35,711,642
Ensembl chr30:35,681,713...35,713,054 		JBrowse link
G MOSPD2 motile sperm domain containing 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr  X:11,147,782...11,200,838
Ensembl chr  X:11,147,958...11,200,117 		JBrowse link
G OSBPL1A oxysterol binding protein like 1A located_in IEA Ensembl GO_REF:0000107 NCBI chr 7:63,995,570...64,223,213
Ensembl chr 7:63,995,184...64,222,157 		JBrowse link
G RMDN3 regulator of microtubule dynamics 3 located_in IEA Ensembl GO_REF:0000107 NCBI chr30:7,878,525...7,895,457
Ensembl chr30:7,851,605...7,896,873 		JBrowse link
G STARD3 StAR related lipid transfer domain containing 3 located_in IEA Ensembl GO_REF:0000107 NCBI chr 9:22,814,782...22,837,525
Ensembl chr 9:22,814,460...22,837,426 		JBrowse link
G STARD3NL STARD3 N-terminal like located_in IEA Ensembl GO_REF:0000107 NCBI chr18:11,732,949...11,784,241
Ensembl chr18:11,733,368...11,784,248 		JBrowse link
endoplasmic reticulum-endosome membrane contact site term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MOSPD2 motile sperm domain containing 2 located_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr  X:11,147,782...11,200,838
Ensembl chr  X:11,147,958...11,200,117 		JBrowse link
G STARD3 StAR related lipid transfer domain containing 3 located_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:22,814,782...22,837,525
Ensembl chr 9:22,814,460...22,837,426 		JBrowse link
G STARD3NL STARD3 N-terminal like located_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr18:11,732,949...11,784,241
Ensembl chr18:11,733,368...11,784,248 		JBrowse link
G TMCC1 transmembrane and coiled-coil domain family 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr20:5,352,304...5,525,798
Ensembl chr20:5,348,446...5,545,546 		JBrowse link
endoplasmic reticulum-plasma membrane contact site term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C2CD2L C2CD2 like located_in IEA Ensembl GO_REF:0000107 NCBI chr 5:14,746,613...14,755,952
Ensembl chr 5:14,747,208...14,755,925 		JBrowse link
G ESYT2 extended synaptotagmin 2 located_in ISO (PMID:27044890), (PMID:30220461) UniProt PMID:27044890 PMID:30220461 NCBI chr16:20,719,115...20,802,991
Ensembl chr16:20,718,499...20,811,468 		JBrowse link
G ESYT3 extended synaptotagmin 3 located_in IEA Ensembl GO_REF:0000107 NCBI chr23:34,645,248...34,692,178
Ensembl chr23:34,645,087...34,691,939 		JBrowse link
G GRAMD1A GRAM domain containing 1A located_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:117,515,381...117,537,906
Ensembl chr 1:117,515,393...117,537,943 		JBrowse link
G GRAMD1B GRAM domain containing 1B located_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:10,809,493...10,982,266
Ensembl chr 5:10,814,512...10,976,833 		JBrowse link
G GRAMD1C GRAM domain containing 1C located_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr33:18,132,860...18,214,363
Ensembl chr33:18,132,862...18,212,894 		JBrowse link
G LOC608110 store-operated calcium entry regulator STIMATE located_in IEA Ensembl GO_REF:0000107 NCBI chr20:36,984,436...37,032,198 JBrowse link
G OSBPL5 oxysterol binding protein like 5 located_in IEA Ensembl GO_REF:0000107 NCBI chr18:47,043,818...47,068,277
Ensembl chr18:47,043,829...47,120,907 		JBrowse link
G SACM1L SAC1 like phosphatidylinositide phosphatase located_in IEA Ensembl GO_REF:0000107 NCBI chr20:42,731,674...42,791,455
Ensembl chr20:42,720,249...42,791,402 		JBrowse link
G SARAF store-operated calcium entry associated regulatory factor located_in ISO (PMID:22464749) UniProt PMID:22464749 NCBI chr16:34,194,880...34,213,346
Ensembl chr16:34,194,354...34,210,444 		JBrowse link
mitochondria-associated endoplasmic reticulum membrane contact site term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACSL4 acyl-CoA synthetase long chain family member 4 located_in IEA Ensembl GO_REF:0000107 NCBI chr  X:82,864,506...82,943,984
Ensembl chr  X:82,866,823...82,916,789 		JBrowse link
G AHCYL1 adenosylhomocysteinase like 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 6:41,945,224...41,983,917
Ensembl chr 6:41,946,974...41,985,643 		JBrowse link
G ATG14 autophagy related 14 located_in IEA Ensembl GO_REF:0000107 NCBI chr 8:31,199,097...31,234,200
Ensembl chr 8:31,201,709...31,234,217 		JBrowse link
G ATG5 autophagy related 5 located_in IEA Ensembl GO_REF:0000107 NCBI chr12:63,565,859...63,692,383
Ensembl chr12:63,567,568...63,683,485 		JBrowse link
G BCAP31 B cell receptor associated protein 31 located_in IEA Ensembl GO_REF:0000107 NCBI chr  X:121,515,417...121,550,373
Ensembl chr  X:121,507,084...121,545,263 		JBrowse link
G CANX calnexin located_in IEA Ensembl GO_REF:0000107 NCBI chr11:1,966,612...1,998,620
Ensembl chr11:1,927,888...1,998,604 		JBrowse link
G CLCC1 chloride channel CLIC like 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 6:42,807,432...42,829,317
Ensembl chr 6:42,807,064...42,829,273 		JBrowse link
G FATE1 fetal and adult testis expressed 1 located_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr  X:119,675,163...119,681,819
Ensembl chr  X:119,675,222...119,681,460 		JBrowse link
G MBOAT7 membrane bound O-acyltransferase domain containing 7 located_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:103,028,000...103,040,299
Ensembl chr 1:103,028,002...103,040,167 		JBrowse link
G PDZD8 PDZ domain containing 8 located_in IEA InterPro
TreeGrafter
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr28:27,768,182...27,853,958
Ensembl chr28:27,772,651...27,853,769 		JBrowse link
G RAB32 RAB32, member RAS oncogene family located_in IEA Ensembl GO_REF:0000107 NCBI chr 1:37,706,809...37,719,044
Ensembl chr 1:37,712,142...37,718,266 		JBrowse link
G RAB38 RAB38, member RAS oncogene family located_in ISO (PMID:25767741) ParkinsonsUK-UCL PMID:25767741 NCBI chr21:11,769,924...11,823,546
Ensembl chr21:11,769,351...11,822,815 		JBrowse link
G SERAC1 serine active site containing 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 1:47,599,802...47,651,034
Ensembl chr 1:47,578,472...47,669,494 		JBrowse link
G STX17 syntaxin 17 located_in IEA Ensembl GO_REF:0000107 NCBI chr11:56,885,874...56,951,714
Ensembl chr11:56,885,174...56,945,767 		JBrowse link
G TMEM41B transmembrane protein 41B located_in IEA Ensembl GO_REF:0000107 NCBI chr21:32,598,075...32,632,614
Ensembl chr21:32,599,425...32,621,761 		JBrowse link
G TMX1 thioredoxin related transmembrane protein 1 located_in
is_active_in		 IEA
ISO		 (PMID:22045338), (PMID:27502484) Ensembl
UniProt		 PMID:22045338 PMID:27502484 GO_REF:0000107 NCBI chr 8:27,541,407...27,556,058
Ensembl chr 8:27,541,460...27,554,681 		JBrowse link
G TMX2 thioredoxin related transmembrane protein 2 located_in
is_active_in		 IEA
ISO		 (PMID:22045338) Ensembl
UniProt		 PMID:22045338 GO_REF:0000107 NCBI chr18:38,480,976...38,490,424
Ensembl chr18:38,481,264...38,490,326 		JBrowse link
G TOMM20 translocase of outer mitochondrial membrane 20 located_in IEA Ensembl GO_REF:0000107 NCBI chr 4:4,785,589...4,802,170
Ensembl chr 4:4,785,584...4,801,006 		JBrowse link
G TOMM40 translocase of outer mitochondrial membrane 40 located_in IEA Ensembl GO_REF:0000107 NCBI chr 1:110,530,233...110,541,049
Ensembl chr 1:110,530,597...110,541,042 		JBrowse link
G VPS13A vacuolar protein sorting 13 homolog A located_in IEA Ensembl GO_REF:0000107 NCBI chr 1:81,191,125...81,426,337
Ensembl chr 1:81,192,349...81,426,322 		JBrowse link
G ZFYVE1 zinc finger FYVE-type containing 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 8:46,353,489...46,407,912
Ensembl chr 8:46,353,761...46,406,038 		JBrowse link
mitochondrial crista junction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MICOS13 mitochondrial contact site and cristae organizing system subunit 13 located_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr20:54,341,571...54,343,606
Ensembl chr20:54,342,007...54,343,607 		JBrowse link
nucleus-vacuole junction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PIK3R4 phosphoinositide-3-kinase regulatory subunit 4 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr23:27,902,500...27,973,609
Ensembl chr23:27,902,840...27,971,892 		JBrowse link
vacuole-isolation membrane contact site term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATG16L1 autophagy related 16 like 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr25:44,761,034...44,800,033
Ensembl chr25:44,761,185...44,798,672 		JBrowse link
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