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ONTOLOGY REPORT - ANNOTATIONS

Term:'de novo' UMP biosynthetic process
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Accession:GO:0044205 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of UMP, uridine monophosphate, starting with the synthesis of (S)-dihydroorotate from bicarbonate; UMP biosynthesis may either occur via reduction by quinone, NAD+ or oxygen.
Synonyms:exact_synonym: 'de novo' UMP biosynthesis


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'de novo' UMP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase involved_in IEA
ISO		 GO_REF:0000041
(MGI:6719158|PMID:33771897)
(PMID:25678555)		 UniProt
RGD		 PMID:25678555 PMID:33771897 GO_REF:0000041 MGI:6719158 NCBI chr 6:25,292,133...25,315,176
Ensembl chr 6:25,292,133...25,319,861 		JBrowse link
G Dhodh dihydroorotate dehydrogenase (quinone) involved_in IEA
ISO		 GO_REF:0000041
(MGI:6282496|PMID:30449682), (MGI:6720231|PMID:6249586)		 UniProt
RGD		 PMID:6249586 PMID:30449682 GO_REF:0000041 MGI:6282496 MGI:6720231 NCBI chr19:37,551,858...37,573,327
Ensembl chr19:37,558,177...37,591,654 		JBrowse link
G Umps uridine monophosphate synthetase involved_in IEA
ISO		 GO_REF:0000041
(MGI:1289111|PMID:2419341), (MGI:6720230|PMID:6154574)		 UniProt
RGD		 PMID:2419341 PMID:6154574 GO_REF:0000041 MGI:1289111 MGI:6720230 NCBI chr11:66,806,107...66,816,520
Ensembl chr11:66,806,045...66,821,903 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19748
    metabolic process 12047
      nitrogen compound metabolic process 10205
        cellular nitrogen compound metabolic process 6643
          pyrimidine-containing compound metabolic process 71
            pyrimidine nucleotide metabolic process 48
              pyrimidine nucleotide biosynthetic process 34
                pyrimidine ribonucleotide biosynthetic process 25
                  UMP biosynthetic process 10
                    'de novo' UMP biosynthetic process 3
Path 2
Term Annotations click to browse term
  biological_process 19748
    metabolic process 12047
      cellular metabolic process 9535
        cellular aromatic compound metabolic process 5843
          nucleobase-containing compound metabolic process 5616
            nucleobase-containing small molecule metabolic process 569
              nucleoside phosphate metabolic process 497
                nucleoside monophosphate metabolic process 85
                  pyrimidine nucleoside monophosphate metabolic process 23
                    pyrimidine ribonucleoside monophosphate metabolic process 16
                      UMP metabolic process 14
                        UMP biosynthetic process 10
                          'de novo' UMP biosynthetic process 3
paths to the root