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ONTOLOGY REPORT - ANNOTATIONS

Term:'de novo' UMP biosynthetic process
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Accession:GO:0044205 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of UMP, uridine monophosphate, starting with the synthesis of (S)-dihydroorotate from bicarbonate; UMP biosynthesis may either occur via reduction by quinone, NAD+ or oxygen.
Synonyms:exact_synonym: 'de novo' UMP biosynthesis


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'de novo' UMP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase involved_in IEA
ISO		 GO_REF:0000041
(PMID:25678555)
(PMID:33771897)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:25678555 PMID:33771897 GO_REF:0000041 GO_REF:0000107 NCBI chr 6:31,012,091...31,035,098
Ensembl chr 6:25,292,133...25,319,861 		JBrowse link
G Dhodh dihydroorotate dehydrogenase involved_in IEA
ISO		 GO_REF:0000041
(PMID:30449682), (PMID:6249586)		 UniProt
RGD		 PMID:6249586 PMID:30449682 GO_REF:0000041 NCBI chr19:54,460,636...54,483,049
Ensembl chr19:37,558,177...37,591,654 		JBrowse link
G Umps uridine monophosphate synthetase involved_in IEA
ISO		 GO_REF:0000041
(PMID:2419341), (PMID:6154574)
GO_REF:0000002		 UniProt
RGD
InterPro		 PMID:2419341 PMID:6154574 GO_REF:0000002 GO_REF:0000041 NCBI chr11:80,311,269...80,321,678
Ensembl chr11:66,806,045...66,821,903 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20567
    cellular process 19557
      metabolic process 12206
        pyrimidine-containing compound metabolic process 76
          pyrimidine nucleotide metabolic process 51
            pyrimidine nucleotide biosynthetic process 37
              pyrimidine ribonucleotide biosynthetic process 25
                UMP biosynthetic process 10
                  'de novo' UMP biosynthetic process 3
Path 2
Term Annotations click to browse term
  biological_process 20567
    cellular process 19557
      metabolic process 12206
        primary metabolic process 10763
          nucleobase-containing compound metabolic process 5900
            nucleobase-containing small molecule metabolic process 733
              nucleoside phosphate metabolic process 699
                nucleoside monophosphate metabolic process 94
                  nucleoside monophosphate biosynthetic process 54
                    pyrimidine nucleoside monophosphate biosynthetic process 19
                      pyrimidine ribonucleoside monophosphate biosynthetic process 11
                        UMP biosynthetic process 10
                          'de novo' UMP biosynthetic process 3
paths to the root