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ONTOLOGY REPORT - ANNOTATIONS

Term:'de novo' UMP biosynthetic process
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Accession:GO:0044205 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of UMP, uridine monophosphate, starting with the synthesis of (S)-dihydroorotate from bicarbonate; UMP biosynthesis may either occur via reduction by quinone, NAD(+) or oxygen.
Synonyms:exact_synonym: 'de novo' UMP biosynthesis

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'de novo' UMP biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase IEA UniProt GO_REF:0000041 NCBI chr 3:111,887,017...111,914,511
Ensembl chr 3:111,887,020...111,914,495 		JBrowse link
G DHODH dihydroorotate dehydrogenase (quinone) IEA UniProt GO_REF:0000041 NCBI chr 6:14,942,898...14,956,000
Ensembl chr 6:14,942,933...14,956,000 		JBrowse link
G UMPS uridine monophosphate synthetase IEA UniProt GO_REF:0000041 NCBI chr13:135,611,857...135,650,656
Ensembl chr13:135,610,058...135,650,604 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16530
    metabolic process 10415
      nitrogen compound metabolic process 8825
        cellular nitrogen compound metabolic process 5635
          pyrimidine-containing compound metabolic process 65
            pyrimidine nucleotide metabolic process 41
              pyrimidine nucleotide biosynthetic process 28
                pyrimidine ribonucleotide biosynthetic process 21
                  UMP biosynthetic process 10
                    'de novo' UMP biosynthetic process 3
Path 2
Term Annotations click to browse term
  biological_process 16530
    metabolic process 10415
      cellular metabolic process 9506
        cellular aromatic compound metabolic process 5087
          nucleobase-containing compound metabolic process 4899
            nucleobase-containing small molecule metabolic process 509
              nucleoside phosphate metabolic process 446
                nucleoside monophosphate metabolic process 73
                  pyrimidine nucleoside monophosphate metabolic process 21
                    pyrimidine ribonucleoside monophosphate metabolic process 16
                      UMP metabolic process 14
                        UMP biosynthetic process 10
                          'de novo' UMP biosynthetic process 3
paths to the root