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ONTOLOGY REPORT - ANNOTATIONS


Term:'de novo' UMP biosynthetic process
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Accession:GO:0044205 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of UMP, uridine monophosphate, starting with the synthesis of (S)-dihydroorotate from bicarbonate; UMP biosynthesis may either occur via reduction by quinone, NAD(+) or oxygen.
Synonyms:exact_synonym: 'de novo' UMP biosynthesis


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'de novo' UMP biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase IEA UniProt GO_REF:0000041 NCBI chr17:21,198,839...21,221,897
Ensembl chr17:21,197,826...21,221,635
JBrowse link
G DHODH dihydroorotate dehydrogenase (quinone) IEA UniProt GO_REF:0000041 NCBI chr 5:77,756,411...77,766,207
Ensembl chr 5:77,756,407...77,774,090
JBrowse link
G UMPS uridine monophosphate synthetase IEA UniProt GO_REF:0000041 NCBI chr33:27,754,592...27,782,517
Ensembl chr33:27,754,643...27,782,514
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16176
    metabolic process 10503
      nitrogen compound metabolic process 8899
        cellular nitrogen compound metabolic process 5714
          pyrimidine-containing compound metabolic process 67
            pyrimidine nucleotide metabolic process 40
              pyrimidine nucleotide biosynthetic process 26
                pyrimidine ribonucleotide biosynthetic process 19
                  UMP biosynthetic process 8
                    'de novo' UMP biosynthetic process 3
Path 2
Term Annotations click to browse term
  biological_process 16176
    metabolic process 10503
      cellular metabolic process 9569
        cellular aromatic compound metabolic process 5094
          nucleobase-containing compound metabolic process 4902
            nucleobase-containing small molecule metabolic process 548
              nucleoside phosphate metabolic process 479
                nucleoside monophosphate metabolic process 76
                  pyrimidine nucleoside monophosphate metabolic process 20
                    pyrimidine ribonucleoside monophosphate metabolic process 15
                      UMP metabolic process 13
                        UMP biosynthetic process 8
                          'de novo' UMP biosynthetic process 3
paths to the root