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Pathways

ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of molecular function
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Accession:GO:0044093 term browser browse the term
Definition:Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.



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activation of adenylate cyclase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GHRHR growth hormone releasing hormone receptor ISO RGD PMID:9845677 RGD:1601338 NCBI chr18:42,030,505...42,046,178
Ensembl chr18:42,030,510...42,046,184
JBrowse link
G LHCGR luteinizing hormone/choriogonadotropin receptor ISO RGD PMID:8440169 RGD:2292602 NCBI chr 3:91,964,415...92,023,821
Ensembl chr 3:91,964,415...92,021,398
JBrowse link
G VIPR2 vasoactive intestinal peptide receptor 2 ISO RGD PMID:8224221 RGD:70054 NCBI chr18:396,379...466,408
Ensembl chr18:396,263...518,102
JBrowse link
activation of cysteine-type endopeptidase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PAWR pro-apoptotic WT1 regulator ISO RGD PMID:10349840 RGD:9835366 NCBI chr 5:101,693,145...101,797,842
Ensembl chr 5:101,693,246...101,797,838
JBrowse link
activation of cysteine-type endopeptidase activity involved in apoptotic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCK cholecystokinin ISO RGD PMID:11964411 RGD:625521 NCBI chr13:25,940,674...25,945,879
Ensembl chr13:25,937,645...25,945,793
JBrowse link
G TNFSF15 TNF superfamily member 15 ISO RGD PMID:11911831 RGD:634236 NCBI chr 1:255,328,731...255,349,508
Ensembl chr 1:255,328,719...255,349,539
JBrowse link
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SMAD3 SMAD family member 3 ISO TGF-beta1-induced cleavage of BAD to its more active 15 kD form RGD PMID:11839804 RGD:2301029 NCBI chr 1:164,998,457...165,124,455
Ensembl chr 1:164,998,103...165,124,449
JBrowse link
activation of GTPase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EIF5 eukaryotic translation initiation factor 5 ISO RGD PMID:10805737 RGD:10755758
G PTK2B protein tyrosine kinase 2 beta ISO RGD PMID:15158121 RGD:1642626 NCBI chr14:11,063,662...11,194,196
Ensembl chr14:11,064,492...11,194,192
JBrowse link
G RASA1 RAS p21 protein activator 1 ISO RGD PMID:8226805 RGD:9999452 NCBI chr 2:94,879,615...94,992,725
Ensembl chr 2:94,878,911...94,993,450
JBrowse link
G RASGRF1 Ras protein specific guanine nucleotide releasing factor 1 ISO RGD PMID:1379346 RGD:10003125 NCBI chr 7:48,121,415...48,246,749
Ensembl chr 7:48,121,419...48,246,749
JBrowse link
G TIAM1 TIAM Rac1 associated GEF 1 ISO RGD PMID:18930714 RGD:10043296 NCBI chr13:194,774,495...195,235,750
Ensembl chr13:194,774,497...195,005,089
JBrowse link
activation of Janus kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGTR1 angiotensin II receptor type 1 ISO RGD PMID:9314843 RGD:6478796 NCBI chr13:88,934,873...88,980,317
Ensembl chr13:88,934,868...88,983,105
JBrowse link
G GHR growth hormone receptor ISO RGD PMID:11244571 RGD:1624962 NCBI chr16:27,126,300...27,422,618
Ensembl chr16:27,126,734...27,421,449
JBrowse link
G PTK2B protein tyrosine kinase 2 beta ISO RGD PMID:11818507 RGD:633057 NCBI chr14:11,063,662...11,194,196
Ensembl chr14:11,064,492...11,194,192
JBrowse link
activation of phospholipase C activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCYAP1R1 ADCYAP receptor type I ISO RGD PMID:8396727 RGD:631732 NCBI chr18:41,915,180...41,972,327
Ensembl chr18:41,917,428...41,972,301
JBrowse link
G ADRA1A adrenoceptor alpha 1A ISO RGD PMID:7935320 RGD:69745 NCBI chr14:10,623,391...10,733,378
Ensembl chr14:10,626,293...10,733,068
JBrowse link
G AGT angiotensinogen ISO RGD PMID:11100981 RGD:1582152 NCBI chr14:59,643,030...59,656,835
Ensembl chr14:59,643,292...59,656,833
JBrowse link
G DLC1 DLC1 Rho GTPase activating protein ISO RGD PMID:7835339 RGD:68218 NCBI chr17:1,169,709...1,637,171
Ensembl chr17:1,170,208...1,637,114
JBrowse link
G GNAQ G protein subunit alpha q ISO RGD PMID:14981460 RGD:1598489 NCBI chr 1:230,607,469...230,906,988
Ensembl chr 1:230,605,265...230,907,674
JBrowse link
G MS4A2 membrane spanning 4-domains A2 ISO RGD PMID:11388899 RGD:1599963 NCBI chr 2:11,400,415...11,420,314
Ensembl chr 2:11,400,420...11,420,298
JBrowse link
activation of phospholipase D activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GNA13 G protein subunit alpha 13 ISO RGD PMID:12435801 RGD:1598460 NCBI chr12:11,922,630...11,966,913
Ensembl chr12:11,922,632...11,966,610
JBrowse link
G HPCA hippocalcin ISO RGD PMID:11211872 RGD:9686445 NCBI chr 6:89,187,544...89,197,049
Ensembl chr 6:89,188,133...89,197,045
JBrowse link
G MARCKS myristoylated alanine rich protein kinase C substrate ISO RGD PMID:16341931 RGD:9685306 NCBI chr 1:79,789,796...79,795,895
Ensembl chr 1:79,789,815...79,795,760
JBrowse link
G PRKCZ protein kinase C zeta ISO RGD PMID:16113073 RGD:1642674 NCBI chr 6:64,073,343...64,159,187
Ensembl chr 6:64,068,577...64,163,472
JBrowse link
activation of protein kinase A activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G UCN urocortin ISO RGD PMID:19460778 RGD:5508168 NCBI chr 3:111,834,082...111,835,932
Ensembl chr 3:111,835,125...111,835,508
JBrowse link
activation of protein kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADNP activity dependent neuroprotector homeobox ISO Fyn kinase RGD PMID:19047645 RGD:2312772 NCBI chr17:52,316,388...52,350,732
Ensembl chr17:52,317,913...52,332,079
JBrowse link
G CAMKK1 calcium/calmodulin dependent protein kinase kinase 1 ISO RGD PMID:16054095 RGD:2311420 NCBI chr12:49,922,837...49,950,668
Ensembl chr12:49,922,855...49,950,605
JBrowse link
G CAMKK2 calcium/calmodulin dependent protein kinase kinase 2 ISO RGD PMID:16054095 RGD:2311420 NCBI chr14:31,307,418...31,366,504
Ensembl chr14:31,312,049...31,366,499
JBrowse link
G DRD2 dopamine receptor D2 ISO RGD PMID:12086672 RGD:1580677 NCBI chr 9:41,068,618...41,135,262
Ensembl chr 9:41,068,779...41,133,599
JBrowse link
G HNF1A HNF1 homeobox A ISO RGD PMID:20841353 RGD:150540305 NCBI chr14:40,868,819...40,888,322
Ensembl chr14:40,868,676...40,888,328
JBrowse link
activation of protein kinase B activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRKCZ protein kinase C zeta ISO in hepatocytes RGD PMID:15007074 RGD:1642700 NCBI chr 6:64,073,343...64,159,187
Ensembl chr 6:64,068,577...64,163,472
JBrowse link
activation of store-operated calcium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G STIM1 stromal interaction molecule 1 ISO RGD PMID:21541286 RGD:7175076 NCBI chr 9:6,066,612...6,270,090
Ensembl chr 9:6,066,617...6,270,575
JBrowse link
G STIM2 stromal interaction molecule 2 ISO RGD PMID:21541286 RGD:7175076 NCBI chr 8:20,456,343...20,609,283
Ensembl chr 8:20,517,587...20,604,319
JBrowse link
negative regulation of activation of Janus kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HNF4A hepatocyte nuclear factor 4 alpha ISO RGD PMID:16584384 RGD:1625011 NCBI chr17:46,783,772...46,847,505
Ensembl chr17:46,783,777...46,847,500
JBrowse link
negative regulation of guanyl-nucleotide exchange factor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EIF2B1 eukaryotic translation initiation factor 2B subunit alpha ISO RGD PMID:9582312 RGD:1581075 NCBI chr14:29,355,497...29,367,918
Ensembl chr14:29,332,233...29,367,918
JBrowse link
G EIF2B4 eukaryotic translation initiation factor 2B subunit delta ISO RGD PMID:9582312 RGD:1581075 NCBI chr 3:111,781,661...111,786,377
Ensembl chr 3:111,781,648...111,786,372
JBrowse link
G EIF2S1 eukaryotic translation initiation factor 2 subunit alpha ISO RGD PMID:9582312 RGD:1581075 NCBI chr 7:91,085,025...91,109,835
Ensembl chr 7:91,085,335...91,109,827
JBrowse link
positive regulation of actin filament binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G POLDIP2 DNA polymerase delta interacting protein 2 ISO RGD PMID:30354218 RGD:124713558 NCBI chr12:44,626,447...44,636,302
Ensembl chr12:44,625,604...44,636,289
JBrowse link
positive regulation of adenylate cyclase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRB1 adrenoceptor beta 1 ISO RGD PMID:21143600 RGD:8693686 NCBI chr14:124,400,330...124,401,739
Ensembl chr14:124,400,330...124,401,739
JBrowse link
G AKAP5 A-kinase anchoring protein 5 ISO RGD PMID:20410303 RGD:7242424 NCBI chr 7:88,538,938...88,544,330
Ensembl chr 7:88,538,984...88,547,392
JBrowse link
G GCG glucagon ISO RGD PMID:2235678 RGD:11556254 NCBI chr15:68,800,557...68,810,268
Ensembl chr15:68,800,560...68,810,242
JBrowse link
G HPCA hippocalcin ISO RGD PMID:15336960 RGD:9686438 NCBI chr 6:89,187,544...89,197,049
Ensembl chr 6:89,188,133...89,197,045
JBrowse link
G TIMP2 TIMP metallopeptidase inhibitor 2 ISO RGD PMID:15901773 RGD:1598578 NCBI chr12:3,254,794...3,300,835
Ensembl chr12:3,254,493...3,300,834
JBrowse link
positive regulation of alkaline phosphatase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITGA2 integrin subunit alpha 2 ISO RGD PMID:10867645 RGD:2307406 NCBI chr16:32,336,240...32,440,311
Ensembl chr16:32,336,292...32,437,103
JBrowse link
G SMAD3 SMAD family member 3 ISO rat gene expressed in mouse osteoblastic cell line MC3T3-E1; TGF-beta down-regulates this activity RGD PMID:12096832 RGD:727387 NCBI chr 1:164,998,457...165,124,455
Ensembl chr 1:164,998,103...165,124,449
JBrowse link
positive regulation of AMPA receptor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNG2 calcium voltage-gated channel auxiliary subunit gamma 2 ISO RGD PMID:16093395 RGD:13515081 NCBI chr 5:11,067,016...11,185,480
Ensembl chr 5:11,067,692...11,185,480
JBrowse link
G CACNG3 calcium voltage-gated channel auxiliary subunit gamma 3 ISO RGD PMID:12771129 RGD:13515082 NCBI chr 3:21,855,847...21,961,191
Ensembl chr 3:21,855,855...21,961,187
JBrowse link
G CACNG4 calcium voltage-gated channel auxiliary subunit gamma 4 ISO RGD PMID:12771129 RGD:13515082 NCBI chr12:13,391,080...13,454,542
Ensembl chr12:13,391,079...13,452,174
JBrowse link
positive regulation of ATP-dependent activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRB2 adrenoceptor beta 2 ISO RGD PMID:8760245 RGD:8548528 NCBI chr 2:150,032,649...150,035,591
Ensembl chr 2:150,033,579...150,040,731
JBrowse link
G TPM1 tropomyosin 1 ISO RGD PMID:11329279 RGD:1600520 NCBI chr 1:108,986,981...109,016,090
Ensembl chr 1:108,986,986...109,020,035
JBrowse link
positive regulation of ATPase-coupled calcium transmembrane transporter activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RGN regucalcin ISO RGD PMID:10797571 RGD:9590178 NCBI chr  X:41,725,660...41,749,736
Ensembl chr  X:41,726,526...41,749,381
JBrowse link
positive regulation of cAMP-dependent protein kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCY10 adenylate cyclase 10 ISO RGD PMID:31172217 RGD:329403053 NCBI chr 4:83,103,768...83,205,015
Ensembl chr 4:83,098,290...83,205,454
JBrowse link
positive regulation of catalytic activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen ISO RGD PMID:11100981 RGD:1582152 NCBI chr14:59,643,030...59,656,835
Ensembl chr14:59,643,292...59,656,833
JBrowse link
G CDC42 cell division cycle 42 ISO RGD PMID:18562481 RGD:5688290 NCBI chr 6:80,035,034...80,089,243
Ensembl chr 6:80,035,123...80,089,233
JBrowse link
G CLPS colipase ISO RGD PMID:8656075 RGD:2303166 NCBI chr 7:31,618,920...31,621,132
Ensembl chr 7:31,618,920...31,621,132
JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 ISO Eno1 RGD PMID:21958194 RGD:10059326 NCBI chr 9:49,982,278...49,986,760
Ensembl chr 9:49,982,284...49,990,508
JBrowse link
G NGB neuroglobin ISO RGD PMID:23036890 RGD:9743969 NCBI chr 7:100,341,974...100,346,263
Ensembl chr 7:100,340,940...100,346,438
JBrowse link
G NPM1 nucleophosmin 1 ISO DNA polymerase alpha RGD PMID:11481036 RGD:1600909 NCBI chr16:52,767,263...52,781,862
Ensembl chr16:52,765,298...52,781,771
JBrowse link
G NPM2 nucleophosmin/nucleoplasmin 2 ISO DNA polymerase alpha, lesser effect than Npm1 RGD PMID:11481036 RGD:1600909 NCBI chr14:6,288,422...6,303,750
Ensembl chr14:6,289,337...6,303,748
JBrowse link
positive regulation of cation channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRB1 adrenoceptor beta 1 ISO RGD PMID:22505670 RGD:6893581 NCBI chr14:124,400,330...124,401,739
Ensembl chr14:124,400,330...124,401,739
JBrowse link
G ASIC2 acid sensing ion channel subunit 2 ISO RGD PMID:12736332 RGD:1298620 NCBI chr12:41,726,987...42,031,997
Ensembl chr12:41,727,002...42,031,991
JBrowse link
G HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 ISO RGD PMID:20806410 RGD:9686372 NCBI chr16:29,439,294...29,808,855
Ensembl chr16:29,439,264...29,808,993
JBrowse link
G KCNJ11 potassium inwardly rectifying channel subfamily J member 11 ISO RGD PMID:23785408 RGD:7296920 NCBI chr 2:41,756,637...41,760,340
Ensembl chr 2:41,757,356...41,765,555
JBrowse link
G NTSR1 neurotensin receptor 1 ISO RGD PMID:19359367 RGD:9743912 NCBI chr17:61,989,601...62,038,299
Ensembl chr17:61,989,402...62,033,548
JBrowse link
positive regulation of chromatin binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KAT2B lysine acetyltransferase 2B ISO Ep300 RGD PMID:20870727 RGD:9590266 NCBI chr13:6,985,151...7,099,771
Ensembl chr13:6,985,235...7,100,345
JBrowse link
G KDM1A lysine demethylase 1A ISO RGD PMID:20418916 RGD:9588315 NCBI chr 6:80,903,407...80,971,875
Ensembl chr 6:80,903,424...80,971,873
JBrowse link
G MBD2 methyl-CpG binding domain protein 2 ISO RGD PMID:25135974 RGD:9589119 NCBI chr 1:103,683,077...103,768,372
Ensembl chr 1:103,735,192...103,752,402
JBrowse link
G MFN2 mitofusin 2 ISO Tfap2a RGD PMID:27997345 RGD:12910740 NCBI chr 6:72,026,512...72,056,439
Ensembl chr 6:72,028,499...72,056,438
JBrowse link
positive regulation of collagen binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITGA2 integrin subunit alpha 2 ISO epithelial cell binding mediated by syndecan-2 RGD PMID:19394307 RGD:2307393 NCBI chr16:32,336,240...32,440,311
Ensembl chr16:32,336,292...32,437,103
JBrowse link
positive regulation of CREB transcription factor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1D calcium voltage-gated channel subunit alpha1 D ISO RGD PMID:16706838 RGD:6906921 NCBI chr13:35,568,534...35,911,483
Ensembl chr13:35,436,519...35,909,662
JBrowse link
positive regulation of cyclic-nucleotide phosphodiesterase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GNAT1 G protein subunit alpha transducin 1 ISO RGD PMID:7878085 RGD:1599022 NCBI chr13:32,671,377...32,678,394
Ensembl chr13:32,671,432...32,678,391
JBrowse link
positive regulation of cyclin-dependent protein serine/threonine kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDC6 cell division cycle 6 ISO RGD PMID:22223646 RGD:10045360 NCBI chr12:22,101,281...22,118,441
Ensembl chr12:22,101,282...22,118,593
JBrowse link
G CDK5RAP1 CDK5 regulatory subunit associated protein 1 ISO RGD PMID:10721722 RGD:632478 NCBI chr17:36,877,570...36,911,344
Ensembl chr17:36,877,650...36,908,019
JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B ISO RGD PMID:22223646 RGD:10045360 NCBI chr 5:59,731,224...59,735,831
Ensembl chr 5:59,731,206...59,735,831
JBrowse link
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX12 arachidonate 12-lipoxygenase, 12S type ISO RGD PMID:15105833 RGD:2313858 NCBI chr12:52,401,861...52,414,913
Ensembl chr12:52,401,810...52,414,903
JBrowse link
G ARRB1 arrestin beta 1 ISO RGD PMID:19171933 RGD:5510006 NCBI chr 9:9,516,944...9,597,446
Ensembl chr 9:9,516,947...9,597,976
JBrowse link
G CCN2 cellular communication network factor 2 ISO caspase 3/7 RGD PMID:19625611 RGD:2314487 NCBI chr 1:31,674,398...31,677,697
Ensembl chr 1:31,674,394...31,677,691
JBrowse link
G FAS Fas cell surface death receptor ISO RGD PMID:15519734 RGD:8662904 NCBI chr14:100,927,305...100,954,781
Ensembl chr14:100,927,089...100,956,716
JBrowse link
G HSF1 heat shock transcription factor 1 ISO RGD PMID:21192280 RGD:10403035 NCBI chr 4:463,531...486,483
Ensembl chr 4:463,393...486,473
JBrowse link
G MAPK9 mitogen-activated protein kinase 9 ISO RGD PMID:14522843 RGD:2304239 NCBI chr 2:78,338,466...78,399,108
Ensembl chr 2:78,338,376...78,399,100
JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha ISO RGD PMID:18322138 RGD:8693423 NCBI chr 2:136,497,780...136,522,630
Ensembl chr 2:136,494,541...136,522,646
JBrowse link
G PYCARD PYD and CARD domain containing ISO RGD PMID:19401709 RGD:5491174 NCBI chr 3:17,305,921...17,307,521
Ensembl chr 3:17,306,099...17,307,786
JBrowse link
G RHOA ras homolog family member A ISO RGD PMID:17425560 RGD:1642961 NCBI chr13:31,918,484...31,991,207
Ensembl chr13:31,918,834...31,986,607
JBrowse link
G WDR35 WD repeat domain 35 ISO RGD PMID:20193664 RGD:11553917 NCBI chr 3:118,209,112...118,279,050
Ensembl chr 3:118,209,139...118,269,452
JBrowse link
positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TNF tumor necrosis factor ISO RGD PMID:12131680 RGD:14995454 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,416
JBrowse link
positive regulation of cytochrome-c oxidase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX5 arachidonate 5-lipoxygenase ISO RGD PMID:15107407 RGD:1578311 NCBI chr14:90,859,209...90,907,084
Ensembl chr14:90,859,016...90,907,094
JBrowse link
G MYO5A myosin VA ISO RGD PMID:29217155 RGD:42721980 NCBI chr 1:119,165,751...119,398,591
Ensembl chr 1:119,165,942...119,394,725
JBrowse link
positive regulation of DNA binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EP300 E1A binding protein p300 ISO RGD PMID:19057620 RGD:2311715 NCBI chr 5:7,311,165...7,394,515
Ensembl chr 5:7,311,171...7,393,760
JBrowse link
G ITGA2 integrin subunit alpha 2 ISO DNA binding by NF-kappaB RGD PMID:19239475 RGD:2307394 NCBI chr16:32,336,240...32,440,311
Ensembl chr16:32,336,292...32,437,103
JBrowse link
G JAK2 Janus kinase 2 ISO Stat3 RGD PMID:15322111 RGD:1641932 NCBI chr 1:216,849,744...217,002,310
Ensembl chr 1:216,848,689...217,002,148
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor ISO RGD PMID:12873812 RGD:10059626 NCBI chr 4:12,455,141...12,460,360
Ensembl chr 4:12,455,122...12,461,078
JBrowse link
G PDX1 pancreatic and duodenal homeobox 1 ISO RGD PMID:11181516 RGD:2311195 NCBI chr11:5,303,609...5,309,063
Ensembl chr11:5,303,609...5,309,063
JBrowse link
G TLR4 toll like receptor 4 ISO RGD PMID:16272348 RGD:1598594 NCBI chr 1:258,044,610...258,054,641
Ensembl chr 1:258,044,610...258,058,970
JBrowse link
positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HNRNPU heterogeneous nuclear ribonucleoprotein U ISO RGD PMID:20554522 RGD:10058983 NCBI chr10:17,475,266...17,497,060
Ensembl chr10:17,477,902...17,497,030
JBrowse link
positive regulation of DNA-binding transcription factor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EP300 E1A binding protein p300 ISO RGD PMID:19057620 RGD:2311715 NCBI chr 5:7,311,165...7,394,515
Ensembl chr 5:7,311,171...7,393,760
JBrowse link
G FOSL1 FOS like 1, AP-1 transcription factor subunit ISO RGD PMID:12371906 RGD:629541 NCBI chr 2:6,430,158...6,436,173
Ensembl chr 2:6,430,153...6,436,173
JBrowse link
G HMGA2 high mobility group AT-hook 2 ISO RGD PMID:9311991 RGD:1601604 NCBI chr 5:30,188,521...30,329,635 JBrowse link
G JAK2 Janus kinase 2 ISO Stat3 RGD PMID:15322111 RGD:1641932 NCBI chr 1:216,849,744...217,002,310
Ensembl chr 1:216,848,689...217,002,148
JBrowse link
G NCOA3 nuclear receptor coactivator 3 ISO RGD PMID:11713241 RGD:727330 NCBI chr17:49,528,275...49,660,471
Ensembl chr17:49,528,179...49,663,200
JBrowse link
G TLR4 toll like receptor 4 ISO RGD PMID:16272348 RGD:1598594 NCBI chr 1:258,044,610...258,054,641
Ensembl chr 1:258,044,610...258,058,970
JBrowse link
G UBE2I ubiquitin conjugating enzyme E2 I ISO glucocorticoid receptor, independent of sumoylation activity or presence of a GME RGD PMID:11812797 RGD:2301354 NCBI chr 3:40,556,556...40,586,382 JBrowse link
positive regulation of DNA-directed DNA polymerase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NPM1 nucleophosmin 1 ISO RGD PMID:8123045 RGD:11535022 NCBI chr16:52,767,263...52,781,862
Ensembl chr16:52,765,298...52,781,771
JBrowse link
positive regulation of dUTP diphosphatase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RGN regucalcin ISO RGD PMID:1315924 RGD:2301218 NCBI chr  X:41,725,660...41,749,736
Ensembl chr  X:41,726,526...41,749,381
JBrowse link
positive regulation of endopeptidase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKIRIN2 akirin 2 ISO MMP-9 RGD PMID:18460465 RGD:2306009 NCBI chr 1:56,047,188...56,075,342
Ensembl chr 1:56,046,327...56,070,163
JBrowse link
positive regulation of epidermal growth factor-activated receptor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA1 adenosine A1 receptor ISO RGD PMID:19574994 RGD:2317913 NCBI chr 9:113,835,279...113,875,899
Ensembl chr 9:113,835,921...113,872,365
JBrowse link
positive regulation of exoribonuclease activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TCEA1 transcription elongation factor A1 ISO RGD PMID:16046193 RGD:9693728 NCBI chr 4:77,109,555...77,138,324
Ensembl chr 4:77,109,594...77,138,320
JBrowse link
positive regulation of glucokinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DUSP12 dual specificity phosphatase 12 ISO increases glucokinase activity by direct dephosphorylation RGD PMID:10913113 RGD:68242 NCBI chr 4:88,811,565...88,818,513
Ensembl chr 4:88,809,565...88,818,411
JBrowse link
G PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 ISO RGD PMID:15047617 RGD:2302684 NCBI chr  X:47,771,751...47,859,079
Ensembl chr  X:47,765,154...47,859,061
JBrowse link
G PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 ISO RGD PMID:16980436 RGD:2304071 NCBI chr 9:67,681,786...67,716,921
Ensembl chr 9:67,681,953...67,709,516
JBrowse link
positive regulation of glutamate-cysteine ligase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GCLM glutamate-cysteine ligase modifier subunit ISO RGD PMID:16137247 RGD:1582663 NCBI chr 4:123,371,198...123,390,130
Ensembl chr 4:123,371,193...123,390,131
JBrowse link
positive regulation of GTP binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RAPGEF3 Rap guanine nucleotide exchange factor 3 ISO Ran-GTP RGD PMID:18689492 RGD:9835375 NCBI chr 5:78,101,286...78,134,150
Ensembl chr 5:78,101,299...78,134,105
JBrowse link
positive regulation of GTPase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMPH amphiphysin ISO RGD PMID:9348539 RGD:631926 NCBI chr 9:108,800,718...108,971,575
Ensembl chr 9:108,799,793...108,971,660
JBrowse link
G BIN1 bridging integrator 1 ISO RGD PMID:9348539 RGD:631926 NCBI chr15:25,328,679...25,379,675
Ensembl chr15:25,328,674...25,383,652
JBrowse link
G GNAO1 G protein subunit alpha o1 ISO RGD PMID:7544301 RGD:2302012 NCBI chr 6:29,416,574...29,592,874
Ensembl chr 6:29,416,708...29,592,516
JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO RGD PMID:17662049 RGD:7240703 NCBI chr 2:69,097,136...69,107,722
Ensembl chr 2:69,097,122...69,108,205
JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 ISO basal and EGF-activated Rac1 RGD PMID:17183546 RGD:2292641 NCBI chr 1:164,381,892...164,469,313
Ensembl chr 1:164,381,845...164,471,226
JBrowse link
G RAP1GDS1 Rap1 GTPase-GDP dissociation stimulator 1 ISO RGD PMID:18348285 RGD:2314690 NCBI chr 8:121,866,803...122,007,492
Ensembl chr 8:121,866,805...122,082,948
JBrowse link
G RASA1 RAS p21 protein activator 1 ISO RGD PMID:14707121 RGD:9999423 NCBI chr 2:94,879,615...94,992,725
Ensembl chr 2:94,878,911...94,993,450
JBrowse link
G RASGRF1 Ras protein specific guanine nucleotide releasing factor 1 ISO RGD PMID:15798216 RGD:10003119 NCBI chr 7:48,121,415...48,246,749
Ensembl chr 7:48,121,419...48,246,749
JBrowse link
G RGN regucalcin ISO RGD PMID:11693188 RGD:9590216 NCBI chr  X:41,725,660...41,749,736
Ensembl chr  X:41,726,526...41,749,381
JBrowse link
G RGS4 regulator of G protein signaling 4 ISO RGD PMID:9430692 PMID:20530129 RGD:7207369 RGD:7207375 NCBI chr 4:87,383,336...87,390,478
Ensembl chr 4:87,383,345...87,390,893
JBrowse link
G S1PR1 sphingosine-1-phosphate receptor 1 ISO RGD PMID:14711826 RGD:1304283 NCBI chr 4:117,064,632...117,069,724
Ensembl chr 4:117,064,755...117,069,650
JBrowse link
positive regulation of guanylate cyclase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GUCA1A guanylate cyclase activator 1A ISO RGD PMID:12545196 RGD:1599357 NCBI chr 7:37,282,630...37,296,713
Ensembl chr 7:37,282,700...37,296,717
JBrowse link
positive regulation of high voltage-gated calcium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNB3 calcium voltage-gated channel auxiliary subunit beta 3 ISO RGD PMID:22187436 RGD:13514092 NCBI chr 5:14,875,524...14,888,224
Ensembl chr 5:14,874,465...14,888,223
JBrowse link
positive regulation of hydrolase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FABP1 fatty acid binding protein 1 ISO peroxisomal medium- and long-chain acyl-CoA thioesterases RGD PMID:16262600 RGD:1626442 NCBI chr 3:57,850,511...57,854,966
Ensembl chr 3:57,850,499...57,854,956
JBrowse link
G GM2A ganglioside GM2 activator ISO Phospholipase D RGD PMID:9770472 RGD:1598995 NCBI chr16:71,742,090...71,767,872
Ensembl chr16:71,742,090...71,754,884
JBrowse link
positive regulation of ion transmembrane transporter activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HTR3A 5-hydroxytryptamine receptor 3A ISO RGD PMID:10854267 RGD:61635 NCBI chr 9:41,575,085...41,589,083
Ensembl chr 9:41,576,796...41,589,538
JBrowse link
G HTR3B 5-hydroxytryptamine receptor 3B ISO RGD PMID:10854267 RGD:61635 NCBI chr 9:41,512,467...41,556,912
Ensembl chr 9:41,512,374...41,556,738
JBrowse link
positive regulation of isoleucine-tRNA ligase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RPL5 ribosomal protein L5 ISO RGD PMID:1665486 RGD:11040680 NCBI chr 4:124,359,786...124,367,612
Ensembl chr 4:124,358,594...124,367,645
JBrowse link
positive regulation of JUN kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL1RN interleukin 1 receptor antagonist ISO RGD PMID:12667655 RGD:1626684
G LOC110258578 interleukin-1 beta-like ISO RGD PMID:12667655 RGD:1626684
G MAP3K1 mitogen-activated protein kinase kinase kinase 1 ISO RGD PMID:9110999 RGD:2293488 NCBI chr16:35,872,301...35,947,097
Ensembl chr16:35,872,131...35,946,987
JBrowse link
G MAP3K5 mitogen-activated protein kinase kinase kinase 5 ISO RGD PMID:20716917 RGD:10412640 NCBI chr 1:27,380,143...27,600,500
Ensembl chr 1:27,380,142...27,600,493
JBrowse link
G PTK2B protein tyrosine kinase 2 beta ISO RGD PMID:15226266 RGD:1642623 NCBI chr14:11,063,662...11,194,196
Ensembl chr14:11,064,492...11,194,192
JBrowse link
G ROR2 receptor tyrosine kinase like orphan receptor 2 ISO RGD PMID:25825749 RGD:11537351 NCBI chr14:2,803,840...3,035,384
Ensembl chr14:2,804,061...3,035,296
JBrowse link
G TIAM1 TIAM Rac1 associated GEF 1 ISO RGD PMID:16203995 RGD:10043312 NCBI chr13:194,774,495...195,235,750
Ensembl chr13:194,774,497...195,005,089
JBrowse link
positive regulation of large conductance calcium-activated potassium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRKG1 protein kinase cGMP-dependent 1 ISO RGD PMID:23407708 RGD:7777099 NCBI chr14:97,558,531...98,793,080
Ensembl chr14:97,558,533...98,793,010
JBrowse link
positive regulation of MAP kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CSK C-terminal Src kinase ISO RGD PMID:10884975 RGD:5134370 NCBI chr 7:58,736,473...58,755,034
Ensembl chr 7:58,736,531...58,755,260
JBrowse link
G HTR2A 5-hydroxytryptamine receptor 2A ISO RGD PMID:15087293 RGD:1624373 NCBI chr11:20,555,939...20,620,225
Ensembl chr11:20,555,963...20,619,625
JBrowse link
G ILK integrin linked kinase ISO inhibits Gsk3b which in turn inhibits Erk/Mapk3 activation RGD PMID:17182785 RGD:2301767 NCBI chr 9:3,145,647...3,152,097
Ensembl chr 9:3,145,608...3,159,858
JBrowse link
G KRAS KRAS proto-oncogene, GTPase ISO RGD PMID:10969813 RGD:1600497 NCBI chr 5:48,508,774...48,546,260
Ensembl chr 5:48,508,811...48,549,358
JBrowse link
G MAP3K1 mitogen-activated protein kinase kinase kinase 1 ISO RGD PMID:9110999 RGD:2293488 NCBI chr16:35,872,301...35,947,097
Ensembl chr16:35,872,131...35,946,987
JBrowse link
G PRKCD protein kinase C delta ISO RGD PMID:16935468 RGD:1642549 NCBI chr13:35,290,835...35,323,245
Ensembl chr13:35,290,610...35,323,356
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase ISO RGD PMID:11941412 RGD:150523765 NCBI chr17:40,470,970...40,524,862
Ensembl chr17:40,471,009...40,524,860
JBrowse link
G TAB1 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 ISO RGD PMID:21607062 RGD:5508182 NCBI chr 5:8,827,363...8,852,814
Ensembl chr 5:8,826,840...8,852,776
JBrowse link
positive regulation of methionine-tRNA ligase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RPL5 ribosomal protein L5 ISO RGD PMID:1665486 RGD:11040680 NCBI chr 4:124,359,786...124,367,612
Ensembl chr 4:124,358,594...124,367,645
JBrowse link
positive regulation of microtubule binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSF1 heat shock transcription factor 1 ISO RGD PMID:21229611 RGD:10403032 NCBI chr 4:463,531...486,483
Ensembl chr 4:463,393...486,473
JBrowse link
positive regulation of mRNA binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HNRNPL heterogeneous nuclear ribonucleoprotein L ISO RGD PMID:19273590 RGD:9999430 NCBI chr 6:47,643,561...47,655,856
Ensembl chr 6:47,643,566...47,657,833
JBrowse link
positive regulation of NAD(P)H oxidase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYBA cytochrome b-245 alpha chain ISO RGD PMID:12631082 RGD:11040676 NCBI chr 6:1,015,212...1,021,422
Ensembl chr 6:1,015,162...1,021,420
JBrowse link
G GNAI2 G protein subunit alpha i2 ISO RGD PMID:27912212 RGD:13507308 NCBI chr13:32,705,326...32,733,804
Ensembl chr13:32,705,321...32,733,794
JBrowse link
G GNAI3 G protein subunit alpha i3 ISO RGD PMID:27912212 RGD:13507308 NCBI chr 4:110,527,363...110,579,331
Ensembl chr 4:110,525,546...110,579,053
JBrowse link
positive regulation of NF-kappaB transcription factor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMH anti-Mullerian hormone ISO RGD PMID:11356848 RGD:70295 NCBI chr 2:76,415,564...76,418,315
Ensembl chr 2:76,414,427...76,418,312
JBrowse link
G CRHR2 corticotropin releasing hormone receptor 2 ISO RGD PMID:19211730 RGD:5130956 NCBI chr18:42,251,755...42,296,457
Ensembl chr18:42,251,749...42,295,467
JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO RGD PMID:9062344 RGD:1600239 NCBI chr 2:69,097,136...69,107,722
Ensembl chr 2:69,097,122...69,108,205
JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta ISO RGD PMID:15939736 RGD:7495757 NCBI chr17:11,289,607...11,348,557
Ensembl chr17:11,289,690...11,348,549
JBrowse link
G ITGB2 integrin subunit beta 2 ISO RGD PMID:9062344 RGD:1600239 NCBI chr13:207,514,281...207,544,108
Ensembl chr13:207,512,950...207,544,107
JBrowse link
G KRAS KRAS proto-oncogene, GTPase ISO RGD PMID:14576830 RGD:1600488 NCBI chr 5:48,508,774...48,546,260
Ensembl chr 5:48,508,811...48,549,358
JBrowse link
G TGFB1 transforming growth factor beta 1 ISO RGD PMID:15781474 RGD:1579751 NCBI chr 6:49,332,169...49,348,642
Ensembl chr 6:49,332,173...49,349,046
JBrowse link
G TLR4 toll like receptor 4 ISO RGD PMID:16651628 RGD:1598593 NCBI chr 1:258,044,610...258,054,641
Ensembl chr 1:258,044,610...258,058,970
JBrowse link
G TNFRSF8 TNF receptor superfamily member 8 ISO RGD PMID:8982082 RGD:730027 NCBI chr 6:72,103,309...72,174,882 JBrowse link
G TRAF2 TNF receptor associated factor 2 ISO RGD PMID:10713108 RGD:2298798
positive regulation of nitric-oxide synthase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CALM1 calmodulin 1 ISO RGD PMID:20529840 RGD:7241266 NCBI chr 7:112,160,823...112,171,754
Ensembl chr 7:112,160,806...112,171,744
JBrowse link
G CALM2 calmodulin 2 ISO RGD PMID:20529840 RGD:7241266 NCBI chr 3:93,371,765...93,386,378
Ensembl chr 3:93,372,045...93,386,218
JBrowse link
G CALM3 calmodulin 3 ISO RGD PMID:20529840 RGD:7241266 NCBI chr 6:52,506,979...52,516,704
Ensembl chr 6:52,506,674...52,516,703
JBrowse link
G KRAS KRAS proto-oncogene, GTPase ISO RGD PMID:14576830 RGD:1600488 NCBI chr 5:48,508,774...48,546,260
Ensembl chr 5:48,508,811...48,549,358
JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 ISO RGD PMID:22870324 RGD:9831169 NCBI chr18:42,464,667...42,509,135
Ensembl chr18:42,432,050...42,512,264
JBrowse link
G PTK2B protein tyrosine kinase 2 beta ISO RGD PMID:21926342 RGD:10041069 NCBI chr14:11,063,662...11,194,196
Ensembl chr14:11,064,492...11,194,192
JBrowse link
G TNF tumor necrosis factor ISO RGD PMID:9537427 RGD:14985259 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,416
JBrowse link
positive regulation of NMDA glutamate receptor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CFL1 cofilin 1 ISO RGD PMID:24089484 RGD:11570552 NCBI chr 2:6,471,558...6,475,019
Ensembl chr 2:6,469,254...6,475,035
JBrowse link
G PINK1 PTEN induced kinase 1 ISO RGD PMID:20698836 RGD:13463453 NCBI chr 6:78,863,195...78,884,663
Ensembl chr 6:78,863,190...78,884,640
JBrowse link
G RGS9 regulator of G protein signaling 9 ISO RGD PMID:16510730 RGD:1599994 NCBI chr12:12,015,321...12,087,982
Ensembl chr12:12,015,321...12,087,976
JBrowse link
positive regulation of oxidative phosphorylation uncoupler activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC25A4 solute carrier family 25 member 4 ISO RGD PMID:18251717 RGD:7242053 NCBI chr15:46,193,498...46,197,989
Ensembl chr15:46,193,746...46,200,987
JBrowse link
positive regulation of oxidoreductase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FDX1 ferredoxin 1 ISO p-nitrophenol hydroxylase, dimethylnitrosamine demethylase RGD PMID:11325963 RGD:4145669 NCBI chr 9:38,376,147...38,399,026
Ensembl chr 9:38,375,984...38,404,832
JBrowse link
positive regulation of P-type sodium:potassium-exchanging transporter activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNM2 dynamin 2 ISO RGD PMID:12205083 RGD:727418 NCBI chr 2:69,474,011...69,574,427
Ensembl chr 2:69,474,031...69,574,424
JBrowse link
positive regulation of phosphatase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RGN regucalcin ISO RGD PMID:9671264 RGD:9590174 NCBI chr  X:41,725,660...41,749,736
Ensembl chr  X:41,726,526...41,749,381
JBrowse link
G RPL5 ribosomal protein L5 ISO RGD PMID:7649987 RGD:2316860 NCBI chr 4:124,359,786...124,367,612
Ensembl chr 4:124,358,594...124,367,645
JBrowse link
positive regulation of phospholipase A2 activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAMK2B calcium/calmodulin dependent protein kinase II beta ISO RGD PMID:15576376 RGD:6482753 NCBI chr18:50,862,225...50,956,263
Ensembl chr18:50,861,466...50,956,225
JBrowse link
positive regulation of phospholipase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HPCA hippocalcin ISO RGD PMID:11211872 RGD:9686445 NCBI chr 6:89,187,544...89,197,049
Ensembl chr 6:89,188,133...89,197,045
JBrowse link
positive regulation of phospholipase C activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTAFR platelet activating factor receptor ISO RGD PMID:8798508 RGD:9999203 NCBI chr 6:85,235,390...85,272,360
Ensembl chr 6:85,235,394...85,261,760
JBrowse link
positive regulation of phosphoprotein phosphatase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G JAK2 Janus kinase 2 ISO Ptpn11 activity RGD PMID:17021051 RGD:1641809 NCBI chr 1:216,849,744...217,002,310
Ensembl chr 1:216,848,689...217,002,148
JBrowse link
G PAWR pro-apoptotic WT1 regulator ISO RGD PMID:23219599 RGD:9835413 NCBI chr 5:101,693,145...101,797,842
Ensembl chr 5:101,693,246...101,797,838
JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha ISO RGD PMID:24265448 RGD:8693600 NCBI chr 2:136,497,780...136,522,630
Ensembl chr 2:136,494,541...136,522,646
JBrowse link
positive regulation of potassium ion transmembrane transporter activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGER advanced glycosylation end-product specific receptor ISO RGD PMID:23212096 RGD:7244285 NCBI chr 7:24,218,116...24,221,162
Ensembl chr 7:24,218,120...24,221,162
JBrowse link
positive regulation of potassium:proton exchanging ATPase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RAPGEF3 Rap guanine nucleotide exchange factor 3 ISO RGD PMID:11897793 RGD:625394 NCBI chr 5:78,101,286...78,134,150
Ensembl chr 5:78,101,299...78,134,105
JBrowse link
positive regulation of protein binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTR3 actin related protein 3 ISO Npc1l1, Rab11a, Myo5b RGD PMID:21844200 RGD:5688279 NCBI chr15:20,104,808...20,171,721
Ensembl chr15:20,104,812...20,167,421
JBrowse link
G CALD1 caldesmon 1 ISO RGD PMID:3384851 RGD:2303065 NCBI chr18:14,267,955...14,486,641
Ensembl chr18:14,267,959...14,486,726
JBrowse link
G HSP90AB1 heat shock protein 90 alpha family class B member 1 ISO Akt1-Hsp90 RGD PMID:18443201 RGD:4108490 NCBI chr 7:39,237,299...39,250,479
Ensembl chr 7:39,244,458...39,250,481
JBrowse link
G HSPA4 heat shock protein family A (Hsp70) member 4 ISO RGD PMID:11415446 RGD:4892111 NCBI chr 2:135,345,724...135,391,112
Ensembl chr 2:135,345,867...135,391,108
JBrowse link
G MAP1LC3B microtubule associated protein 1 light chain 3 beta ISO RGD PMID:7908909 RGD:633201 NCBI chr 6:1,919,879...1,941,069
Ensembl chr 6:1,915,387...1,941,069
JBrowse link
G PACS1 phosphofurin acidic cluster sorting protein 1 ISO RGD PMID:9695949 RGD:633354 NCBI chr 2:6,138,345...6,277,309
Ensembl chr 2:6,138,351...6,174,632
JBrowse link
G PLK2 polo like kinase 2 ISO Sipa1l1 binding to Btcr and Fbxw11 RGD PMID:18723513 RGD:7241135 NCBI chr16:37,299,116...37,305,114
Ensembl chr16:37,299,119...37,305,114
JBrowse link
G RAMP1 receptor activity modifying protein 1 ISO RGD PMID:11556887 RGD:1299115 NCBI chr15:137,490,440...137,535,555
Ensembl chr15:137,490,356...137,535,553
JBrowse link
G RAMP2 receptor activity modifying protein 2 ISO RGD PMID:11556887 RGD:1299115 NCBI chr12:20,092,204...20,094,426
Ensembl chr12:20,092,196...20,094,469
JBrowse link
G TRIM28 tripartite motif containing 28 ISO RGD PMID:12748187 RGD:1299608 NCBI chr 6:63,094,382...63,101,532
Ensembl chr 6:63,094,648...63,101,531
JBrowse link
positive regulation of protein kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AXIN1 axin 1 ISO RGD PMID:15228590 RGD:1304344 NCBI chr 3:41,344,908...41,393,999
Ensembl chr 3:41,337,071...41,393,997
JBrowse link
G AXIN2 axin 2 ISO RGD PMID:9566905 RGD:68736 NCBI chr12:12,311,293...12,343,207
Ensembl chr12:12,311,298...12,343,200
JBrowse link
G CAMKK1 calcium/calmodulin dependent protein kinase kinase 1 ISO RGD PMID:7642608 RGD:632489 NCBI chr12:49,922,837...49,950,668
Ensembl chr12:49,922,855...49,950,605
JBrowse link
G CCNB1 cyclin B1 ISO histone H1 RGD PMID:15291744 RGD:1578405 NCBI chr16:47,338,239...47,348,385
Ensembl chr16:47,338,110...47,348,377
JBrowse link
G DAG1 dystroglycan 1 ISO RGD PMID:18556591 RGD:11541067 NCBI chr13:32,028,019...32,092,450
Ensembl chr13:32,029,522...32,092,450
JBrowse link
G DAXX death domain associated protein ISO RGD PMID:21572393 RGD:9587767 NCBI chr 7:29,676,854...29,681,145
Ensembl chr 7:29,676,856...29,681,110
JBrowse link
G PPP1R9A protein phosphatase 1 regulatory subunit 9A ISO RGD PMID:9653190 RGD:8554053 NCBI chr 9:74,635,285...74,944,050
Ensembl chr 9:74,635,403...74,940,362
JBrowse link
G SDC4 syndecan 4 ISO RGD PMID:12571249 RGD:1580031 NCBI chr17:47,650,387...47,670,499 JBrowse link
positive regulation of protein kinase C activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MARCKS myristoylated alanine rich protein kinase C substrate ISO RGD PMID:16341931 RGD:9685306 NCBI chr 1:79,789,796...79,795,895
Ensembl chr 1:79,789,815...79,795,760
JBrowse link
G ROR2 receptor tyrosine kinase like orphan receptor 2 ISO RGD PMID:25825749 RGD:11537351 NCBI chr14:2,803,840...3,035,384
Ensembl chr14:2,804,061...3,035,296
JBrowse link
positive regulation of protein serine/threonine kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSP90AB1 heat shock protein 90 alpha family class B member 1 ISO Akt1 RGD PMID:18443201 RGD:4108490 NCBI chr 7:39,237,299...39,250,479
Ensembl chr 7:39,244,458...39,250,481
JBrowse link
positive regulation of Rho guanyl-nucleotide exchange factor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G POLDIP2 DNA polymerase delta interacting protein 2 ISO RGD PMID:30726115 RGD:124713559 NCBI chr12:44,626,447...44,636,302
Ensembl chr12:44,625,604...44,636,289
JBrowse link
positive regulation of store-operated calcium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP4 bone morphogenetic protein 4 ISO RGD PMID:20844246 RGD:8801954 NCBI chr 1:183,415,989...183,422,888
Ensembl chr 1:183,416,146...183,422,637
JBrowse link
positive regulation of superoxide dismutase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RGN regucalcin ISO RGD PMID:15375603 RGD:9590277 NCBI chr  X:41,725,660...41,749,736
Ensembl chr  X:41,726,526...41,749,381
JBrowse link
positive regulation of threonine-tRNA ligase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RPL5 ribosomal protein L5 ISO RGD PMID:8049265 RGD:1556518 NCBI chr 4:124,359,786...124,367,612
Ensembl chr 4:124,358,594...124,367,645
JBrowse link
positive regulation of voltage-gated calcium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA2D1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 ISO RGD PMID:20478999 RGD:13514093 NCBI chr 9:97,781,057...98,265,925
Ensembl chr 9:97,781,090...98,266,969
JBrowse link
G CACNB3 calcium voltage-gated channel auxiliary subunit beta 3 ISO RGD PMID:15024042 RGD:13514097 NCBI chr 5:14,875,524...14,888,224
Ensembl chr 5:14,874,465...14,888,223
JBrowse link
G CACNB4 calcium voltage-gated channel auxiliary subunit beta 4 ISO RGD PMID:12821675 RGD:737839 NCBI chr15:402,801...455,691
Ensembl chr15:186,434...459,856
JBrowse link
G KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 ISO RGD PMID:14679187 RGD:7243967 NCBI chr13:198,051,281...198,059,444
Ensembl chr13:198,051,282...198,059,296
JBrowse link
G KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 ISO RGD PMID:14679187 RGD:7243967 NCBI chr13:197,979,749...197,980,974
Ensembl chr13:197,980,145...197,980,516
JBrowse link
G KCNE3 potassium voltage-gated channel subfamily E regulatory subunit 3 ISO RGD PMID:14679187 RGD:7243967 NCBI chr 9:8,810,716...8,822,191
Ensembl chr 9:8,810,720...8,822,494
JBrowse link
G S100A1 S100 calcium binding protein A1 ISO RGD PMID:19657060 RGD:7205633 NCBI chr 4:96,007,026...96,012,305
Ensembl chr 4:96,007,028...96,012,310
JBrowse link
positive regulation of voltage-gated chloride channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLCN2 chloride voltage-gated channel 2 ISO RGD PMID:29344669 RGD:213230158 NCBI chr13:122,234,731...122,249,889
Ensembl chr13:122,234,736...122,249,867
JBrowse link
G PTAFR platelet activating factor receptor ISO RGD PMID:8168510 RGD:61717 NCBI chr 6:85,235,390...85,272,360
Ensembl chr 6:85,235,394...85,261,760
JBrowse link
positive regulation of voltage-gated potassium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC8 ATP binding cassette subfamily C member 8 ISO RGD PMID:12183335 RGD:728122 NCBI chr 2:41,666,974...41,754,624
Ensembl chr 2:41,666,909...41,754,620
JBrowse link
G AMIGO1 adhesion molecule with Ig like domain 1 ISO RGD PMID:22056818 RGD:14390155 NCBI chr 4:110,620,429...110,631,549
Ensembl chr 4:110,620,444...110,628,833
JBrowse link
G KCNA1 potassium voltage-gated channel subfamily A member 1 ISO RGD PMID:21943416 RGD:7242916 NCBI chr 5:65,556,837...65,565,880
Ensembl chr 5:65,561,962...65,565,116
JBrowse link
G KCNC1 potassium voltage-gated channel subfamily C member 1 ISO RGD PMID:21943417 RGD:12910700 NCBI chr 2:41,362,208...41,407,935
Ensembl chr 2:41,362,347...41,408,127
JBrowse link
G KCNC2 potassium voltage-gated channel subfamily C member 2 ISO RGD PMID:21943417 RGD:12910700 NCBI chr 5:38,326,408...38,535,826
Ensembl chr 5:38,326,414...38,533,110
JBrowse link
G KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 ISO RGD PMID:7568179 RGD:12910723 NCBI chr13:198,051,281...198,059,444
Ensembl chr13:198,051,282...198,059,296
JBrowse link
G KCNK3 potassium two pore domain channel subfamily K member 3 ISO RGD PMID:31347976 RGD:151347452 NCBI chr 3:112,322,446...112,359,212
Ensembl chr 3:112,322,446...112,359,212
JBrowse link
positive regulation of voltage-gated sodium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GPER1 G protein-coupled estrogen receptor 1 ISO RGD PMID:24097558 RGD:39939085 NCBI chr 3:711,427...715,982
Ensembl chr 3:712,160...715,980
JBrowse link
G KIF5B kinesin family member 5B ISO RGD PMID:24198377 RGD:11073607 NCBI chr10:42,637,105...42,693,551
Ensembl chr10:42,637,109...42,693,491
JBrowse link
receptor transactivation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM17 ADAM metallopeptidase domain 17 ISO RGD PMID:25232008 RGD:13703036 NCBI chr 3:126,795,513...126,853,995
Ensembl chr 3:126,795,426...126,853,995
JBrowse link

Term paths to the root