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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of digestive system process
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Accession:GO:0044058 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.


show annotations for term's descendants           Sort by:
negative regulation of defecation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crhr2 corticotropin releasing hormone receptor 2 IMP RGD PMID:21277852 RGD:5491003 NCBI chr 4:84,222,897...84,265,924
Ensembl chr 4:84,224,002...84,265,904 		JBrowse link
G Npsr1 neuropeptide S receptor 1 IMP RGD PMID:21708257 RGD:9831204 NCBI chr 8:22,606,946...22,831,558
Ensembl chr 8:22,606,946...22,831,558 		JBrowse link
negative regulation of gastric acid secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpr39 G protein-coupled receptor 39 acts_upstream_of_or_within ISO MGI:3723512 (MGI:3722947|PMID:17030183) RGD PMID:17030183 MGI:3722947 NCBI chr13:37,115,258...37,327,312
Ensembl chr13:37,115,102...37,328,267 		JBrowse link
G Nmu neuromedin U involved_in IDA PMID:12584108 UniProt PMID:12584108 RGD:1642125 NCBI chr14:31,844,564...31,872,196
Ensembl chr14:31,844,728...31,872,192 		JBrowse link
G Ptger3 prostaglandin E receptor 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434 		JBrowse link
G Tff2 trefoil factor 2 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:2179101 (MGI:2158108|PMID:11805131)		 RGD PMID:11805131 PMID:21873635 MGI:2158108, RGD:13792537 NCBI chr20:9,215,750...9,219,619
Ensembl chr20:9,215,761...9,219,619 		JBrowse link
negative regulation of gastric emptying term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nmu neuromedin U involved_in IDA PMID:12584108 UniProt PMID:12584108 RGD:1642125 NCBI chr14:31,844,564...31,872,196
Ensembl chr14:31,844,728...31,872,192 		JBrowse link
negative regulation of gastrin-induced gastric acid secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:15961884 RGD:10043339 NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434 		JBrowse link
G Sct secretin involved_in IDA
IBA		 PMID:21873635 RGD
GO_Central		 PMID:11123201 PMID:21873635 RGD:9590235, RGD:13792537 NCBI chr 1:196,382,941...196,383,635
Ensembl chr 1:196,382,856...196,383,658 		JBrowse link
negative regulation of intestinal absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg2 ATP binding cassette subfamily G member 2 IMP RGD PMID:23333829 RGD:11099975 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409 		JBrowse link
G Hamp hepcidin antimicrobial peptide involved_in ISO (PMID:12469120) RGD PMID:12469120 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891 		JBrowse link
G Isx intestine-specific homeobox acts_upstream_of_or_within ISO MGI:3703167 (MGI:5638293|PMID:25701869) RGD PMID:25701869 MGI:5638293 NCBI chr19:13,218,552...13,239,754
Ensembl chr19:13,218,552...13,239,760 		JBrowse link
negative regulation of intestinal cholesterol absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg5 ATP binding cassette subfamily G member 5 involved_in ISO (PMID:11099417) RGD PMID:11099417 NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563 		JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 involved_in ISO (PMID:11099417) RGD PMID:11099417 NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912 		JBrowse link
negative regulation of intestinal phytosterol absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg5 ATP binding cassette subfamily G member 5 involved_in ISO (PMID:11099417) RGD PMID:11099417 NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563 		JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 involved_in ISO (PMID:11099417) RGD PMID:11099417 NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912 		JBrowse link
negative regulation of pancreatic juice secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 involved_in IEA
ISO		 GO_REF:0000107
(MGI:3822255|PMID:18806227)		 Ensembl
RGD		 PMID:18806227 GO_REF:0000107 MGI:3822255 NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722 		JBrowse link
G Stk39 serine threonine kinase 39 involved_in ISO (MGI:5002793|PMID:21317537) RGD PMID:21317537 MGI:5002793 NCBI chr 3:52,913,583...53,179,060
Ensembl chr 3:52,913,585...53,179,060 		JBrowse link
G Wnk1 WNK lysine deficient protein kinase 1 acts_upstream_of_or_within ISO (MGI:5002793|PMID:21317537) RGD PMID:21317537 MGI:5002793 NCBI chr 4:153,128,334...153,253,905
Ensembl chr 4:153,128,334...153,253,905 		JBrowse link
G Wnk3 WNK lysine deficient protein kinase 3 involved_in ISO (MGI:5002793|PMID:21317537) RGD PMID:21317537 MGI:5002793 NCBI chr  X:20,156,260...20,299,252
Ensembl chr  X:20,157,041...20,296,821 		JBrowse link
G Wnk4 WNK lysine deficient protein kinase 4 acts_upstream_of_or_within ISO (MGI:5002793|PMID:21317537) RGD PMID:21317537 MGI:5002793 NCBI chr10:86,202,552...86,219,655
Ensembl chr10:86,188,812...86,231,829 		JBrowse link
negative regulation of saliva secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Neurog1 neurogenin 1 involved_in ISO UniProtKB:Q6ZNK6|UniProtKB:Q8TF63 (PMID:23419067) RGD PMID:23419067 NCBI chr17:8,362,878...8,364,397
Ensembl chr17:8,362,821...8,364,571 		JBrowse link
G Tifab TIFA inhibitor involved_in ISO UniProtKB:Q8TF63|UniProtKB:Q92886 (PMID:23419067) RGD PMID:23419067 NCBI chr17:8,433,406...8,436,541
Ensembl chr17:8,431,635...8,436,592 		JBrowse link
positive regulation of digestive system process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crh corticotropin releasing hormone IDA gut paracellular permeability RGD PMID:17234701 RGD:5491013 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919 		JBrowse link
positive regulation of hindgut contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Oxt oxytocin/neurophysin I prepropeptide IDA RGD PMID:19258489 RGD:2304084 NCBI chr 3:117,782,650...117,783,490
Ensembl chr 3:117,782,650...117,783,490 		JBrowse link
G Pawr pro-apoptotic WT1 regulator IDA RGD PMID:14724155 RGD:9835340 NCBI chr 7:43,645,028...43,725,033
Ensembl chr 7:43,645,084...43,725,028 		JBrowse link
positive regulation of intestinal cholesterol absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acat2 acetyl-CoA acetyltransferase 2 involved_in ISO (MGI:5302163|PMID:22045928) RGD PMID:22045928 MGI:5302163 NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821 		JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 involved_in ISO (MGI:3588413|PMID:12393855) RGD PMID:12393855 MGI:3588413 NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166 		JBrowse link
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5574251|PMID:24650549)		 UniProt
RGD		 PMID:24650549 GO_REF:0000024 MGI:5574251 NCBI chr10:104,242,223...104,246,589
Ensembl chr10:104,242,223...104,246,589 		JBrowse link
G Lpcat3 lysophosphatidylcholine acyltransferase 3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5780634|PMID:26833026)		 UniProt
RGD		 PMID:26833026 GO_REF:0000024 MGI:5780634 NCBI chr 4:157,468,397...157,509,889
Ensembl chr 4:157,468,290...157,509,880 		JBrowse link
positive regulation of intestinal epithelial structure maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a5 solute carrier family 22 member 5 involved_in ISO (PMID:18005709) RGD PMID:18005709 NCBI chr10:38,008,303...38,035,474
Ensembl chr10:38,008,311...38,035,309 		JBrowse link
positive regulation of intestinal lipid absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prap1 proline-rich acidic protein 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6706092|PMID:33168624)		 UniProt
RGD		 PMID:33168624 GO_REF:0000024 MGI:6706092 NCBI chr 1:194,883,078...194,886,874
Ensembl chr 1:194,883,078...194,886,872 		JBrowse link
positive regulation of pancreatic juice secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 involved_in ISO (MGI:3822255|PMID:18806227) RGD PMID:18806227 MGI:3822255 NCBI chr 1:95,041,967...95,047,377
Ensembl chr 1:95,041,967...95,047,377 		JBrowse link
G Sct secretin involved_in IDA
IBA		 PMID:21873635 RGD
GO_Central		 PMID:11123201 PMID:21873635 RGD:9590235, RGD:13792537 NCBI chr 1:196,382,941...196,383,635
Ensembl chr 1:196,382,856...196,383,658 		JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 IDA RGD PMID:2755938 RGD:10044250 NCBI chr18:35,870,723...35,882,693
Ensembl chr18:35,824,550...35,882,642 		JBrowse link
positive regulation of saliva secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp1 aquaporin 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:15727941), (PMID:9096382)		 UniProt
RGD		 PMID:9096382 PMID:15727941 GO_REF:0000024 NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690 		JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha involved_in ISS
ISO		 GO_REF:0000024
(MGI:4943357|PMID:21435446)		 UniProt
RGD		 PMID:21435446 GO_REF:0000024 MGI:4943357 NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974 		JBrowse link
G Tac4 tachykinin precursor 4 acts_upstream_of_or_within ISO (MGI:1926622|PMID:11062498) RGD PMID:11062498 MGI:1926622 NCBI chr10:80,207,824...80,216,156
Ensembl chr10:80,207,610...80,216,156 		JBrowse link
positive regulation of small intestinal transit term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ghrl ghrelin and obestatin prepropeptide IDA RGD PMID:21874246 RGD:12910732 NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621 		JBrowse link
G Ghsr growth hormone secretagogue receptor IMP RGD PMID:21874246 PMID:15890336 RGD:12910732, RGD:12907565 NCBI chr 2:110,268,489...110,271,865
Ensembl chr 2:110,268,489...110,271,865 		JBrowse link
regulation of gastric acid secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hip1r huntingtin interacting protein 1 related involved_in ISO (MGI:3801545|PMID:18535670) RGD PMID:18535670 MGI:3801545 NCBI chr12:32,590,164...32,618,841
Ensembl chr12:32,590,165...32,618,734 		JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:3611738|PMID:16314573), (MGI:5292649|PMID:19491250)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:16314573 PMID:19491250 GO_REF:0000024 GO_REF:0000107 MGI:3611738 MGI:5292649 NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669 		JBrowse link
regulation of gastric motility term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ghrl ghrelin and obestatin prepropeptide IDA RGD PMID:23525979 RGD:12907567 NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621 		JBrowse link
G Ghsr growth hormone secretagogue receptor IMP RGD PMID:23525979 RGD:12907567 NCBI chr 2:110,268,489...110,271,865
Ensembl chr 2:110,268,489...110,271,865 		JBrowse link
G Tymp thymidine phosphorylase involved_in ISO (PMID:9924029) RGD PMID:9924029 NCBI chr 7:120,438,768...120,444,088
Ensembl chr 7:120,438,770...120,443,874
Ensembl chr 7:120,438,770...120,443,874 		JBrowse link
regulation of hindgut contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ghsr growth hormone secretagogue receptor IMP RGD PMID:16873401 RGD:1625276 NCBI chr 2:110,268,489...110,271,865
Ensembl chr 2:110,268,489...110,271,865 		JBrowse link
regulation of intestinal absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A IMP RGD PMID:22049154 RGD:8657330 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Epb41 erythrocyte membrane protein band 4.1 involved_in ISO (MGI:5496297|PMID:23460639) RGD PMID:23460639 MGI:5496297 NCBI chr 5:144,110,010...144,264,037
Ensembl chr 5:144,111,906...144,237,821 		JBrowse link
regulation of intestinal cholesterol absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa1 apolipoprotein A1 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (MGI:1339009|PMID:10073953)
PMID:21873635		 RGD PMID:10073953 PMID:21873635 MGI:1339009, RGD:13792537 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035 		JBrowse link
G Apoa2 apolipoprotein A2 acts_upstream_of_or_within ISO MGI:2157148 (MGI:84652|PMID:8962133) RGD PMID:8962133 MGI:84652 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355 		JBrowse link
G Apoa4 apolipoprotein A4 acts_upstream_of_or_within
involved_in		 ISO
IBA
IEA		 MGI:2157162 (MGI:1096980|PMID:9323588)
PMID:21873635
GO_REF:0000107		 RGD
Ensembl		 PMID:9323588 PMID:21873635 GO_REF:0000107 MGI:1096980, RGD:13792537 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469 		JBrowse link
G Lep leptin acts_upstream_of_or_within ISO (MGI:2386518|PMID:12114517) RGD PMID:12114517 MGI:2386518 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
regulation of intestinal epithelial structure maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Neurod1 neuronal differentiation 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5009210|PMID:9512516)		 UniProt
RGD		 PMID:9512516 GO_REF:0000024 MGI:5009210 NCBI chr 3:64,360,222...64,363,526
Ensembl chr 3:64,359,395...64,363,649 		JBrowse link
regulation of intestinal lipid absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dgat1 diacylglycerol O-acyltransferase 1 IMP RGD PMID:18768481 RGD:10400848 NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299 		JBrowse link
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 involved_in ISS
ISO		 GO_REF:0000024
(MGI:4947032|PMID:21177474)		 UniProt
RGD		 PMID:21177474 GO_REF:0000024 MGI:4947032 NCBI chr10:104,242,223...104,246,589
Ensembl chr10:104,242,223...104,246,589 		JBrowse link
regulation of saliva secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf10 fibroblast growth factor 10 involved_in ISO (PMID:19102732) RGD PMID:19102732 NCBI chr 2:50,801,897...50,875,428
Ensembl chr 2:50,800,992...50,876,866 		JBrowse link
G Oprk1 opioid receptor, kappa 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:1197118|PMID:9463367)		 UniProt
RGD		 PMID:9463367 GO_REF:0000024 MGI:1197118 NCBI chr 5:13,860,016...13,877,823
Ensembl chr 5:13,860,021...13,877,823 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19738
    multicellular organismal process 9179
      system process 3526
        digestive system process 116
          regulation of digestive system process 48
            negative regulation of digestive system process + 19
            positive regulation of digestive system process + 17
            regulation of defecation + 2
            regulation of gastric acid secretion + 7
            regulation of gastric motility + 4
            regulation of hindgut contraction + 3
            regulation of intestinal absorption + 17
            regulation of intestinal epithelial structure maintenance + 2
            regulation of pancreatic juice secretion + 8
            regulation of saliva secretion + 7
            regulation of small intestinal transit + 2
Path 2
Term Annotations click to browse term
  biological_process 19738
    biological regulation 13436
      regulation of biological process 13021
        regulation of multicellular organismal process 3355
          regulation of system process 668
            regulation of digestive system process 48
              negative regulation of digestive system process + 19
              positive regulation of digestive system process + 17
              regulation of defecation + 2
              regulation of gastric acid secretion + 7
              regulation of gastric motility + 4
              regulation of hindgut contraction + 3
              regulation of intestinal absorption + 17
              regulation of intestinal epithelial structure maintenance + 2
              regulation of pancreatic juice secretion + 8
              regulation of saliva secretion + 7
              regulation of small intestinal transit + 2
paths to the root