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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of digestive system process
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Accession:GO:0044058 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.


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regulation of digestive system process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Oxt oxytocin/neurophysin I prepropeptide IDA RGD PMID:12690433 RGD:2304324 NCBI chr 3:117,782,650...117,783,490
Ensembl chr 3:117,782,650...117,783,490
JBrowse link
G Oxtr oxytocin receptor IMP RGD PMID:12690433 RGD:2304324 NCBI chr 4:145,598,549...145,614,674
Ensembl chr 4:145,599,561...145,614,674
JBrowse link
negative regulation of gastric acid secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpr39 G protein-coupled receptor 39 acts_upstream_of_or_within ISO MGI:3723512 (MGI:3722947|PMID:17030183) RGD PMID:17030183 MGI:3722947 NCBI chr13:37,115,258...37,327,312
Ensembl chr13:37,115,102...37,328,267
JBrowse link
G Nmu neuromedin U involved_in IDA PMID:12584108 UniProt PMID:12584108 RGD:1642125 NCBI chr14:31,844,564...31,872,196
Ensembl chr14:31,844,728...31,872,192
JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide IDA RGD PMID:11764003 RGD:2304192 NCBI chr 3:117,782,650...117,783,490
Ensembl chr 3:117,782,650...117,783,490
JBrowse link
G Oxtr oxytocin receptor IMP RGD PMID:11764003 RGD:2304192 NCBI chr 4:145,598,549...145,614,674
Ensembl chr 4:145,599,561...145,614,674
JBrowse link
G Ptger3 prostaglandin E receptor 3 involved_in IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:15961884 PMID:21873635 RGD:10043339, RGD:13792537 NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434
JBrowse link
G Tff2 trefoil factor 2 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:2179101 (MGI:2158108|PMID:11805131)
RGD PMID:11805131 PMID:21873635 MGI:2158108, RGD:13792537 NCBI chr20:9,215,750...9,219,619
Ensembl chr20:9,215,761...9,219,619
JBrowse link
G Ucn urocortin IDA RGD PMID:21540451 RGD:5490560 NCBI chr 6:25,238,120...25,238,950
Ensembl chr 6:25,238,120...25,238,950
JBrowse link
negative regulation of gastric emptying term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nmu neuromedin U involved_in IDA PMID:12584108 UniProt PMID:12584108 RGD:1642125 NCBI chr14:31,844,564...31,872,196
Ensembl chr14:31,844,728...31,872,192
JBrowse link
G Ptger1 prostaglandin E receptor 1 IMP RGD PMID:10807413 RGD:10043357 NCBI chr19:24,470,258...24,473,687
Ensembl chr19:24,467,532...24,473,559
JBrowse link
negative regulation of gastrin-induced gastric acid secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:15961884 RGD:10043339 NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434
JBrowse link
G Sct secretin involved_in IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:11123201 PMID:21873635 RGD:9590235, RGD:13792537 NCBI chr 1:196,382,941...196,383,635
Ensembl chr 1:196,382,856...196,383,658
JBrowse link
negative regulation of intestinal absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg2 ATP binding cassette subfamily G member 2 IMP RGD PMID:23333829 RGD:11099975 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Hamp hepcidin antimicrobial peptide involved_in ISO (PMID:12469120) RGD PMID:12469120 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
JBrowse link
G Isx intestine-specific homeobox acts_upstream_of_or_within ISO MGI:3703167 (MGI:5638293|PMID:25701869) RGD PMID:25701869 MGI:5638293 NCBI chr19:13,218,552...13,239,754
Ensembl chr19:13,218,552...13,239,760
JBrowse link
negative regulation of intestinal cholesterol absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg5 ATP binding cassette subfamily G member 5 involved_in ISO (PMID:11099417) RGD PMID:11099417 NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563
JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 involved_in ISO (PMID:11099417) RGD PMID:11099417 NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912
JBrowse link
negative regulation of intestinal phytosterol absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg5 ATP binding cassette subfamily G member 5 involved_in ISO (PMID:11099417) RGD PMID:11099417 NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563
JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 involved_in ISO (PMID:11099417) RGD PMID:11099417 NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912
JBrowse link
negative regulation of pancreatic juice secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 involved_in IEA
ISO
GO_REF:0000107
(MGI:3822255|PMID:18806227)
Ensembl
RGD
PMID:18806227 GO_REF:0000107 MGI:3822255 NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722
JBrowse link
G Stk39 serine threonine kinase 39 involved_in ISO (MGI:5002793|PMID:21317537) RGD PMID:21317537 MGI:5002793 NCBI chr 3:52,913,583...53,179,060
Ensembl chr 3:52,913,585...53,179,060
JBrowse link
G Wnk1 WNK lysine deficient protein kinase 1 acts_upstream_of_or_within ISO (MGI:5002793|PMID:21317537) RGD PMID:21317537 MGI:5002793 NCBI chr 4:153,128,334...153,253,905
Ensembl chr 4:153,128,334...153,253,905
JBrowse link
G Wnk3 WNK lysine deficient protein kinase 3 involved_in ISO (MGI:5002793|PMID:21317537) RGD PMID:21317537 MGI:5002793 NCBI chr  X:20,156,260...20,299,252
Ensembl chr  X:20,157,041...20,296,821
JBrowse link
G Wnk4 WNK lysine deficient protein kinase 4 acts_upstream_of_or_within ISO (MGI:5002793|PMID:21317537) RGD PMID:21317537 MGI:5002793 NCBI chr10:86,202,552...86,219,655
Ensembl chr10:86,188,812...86,231,829
JBrowse link
negative regulation of saliva secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Neurog1 neurogenin 1 involved_in ISO UniProtKB:Q6ZNK6|UniProtKB:Q8TF63 (PMID:23419067) RGD PMID:23419067 NCBI chr17:8,362,878...8,364,397
Ensembl chr17:8,362,821...8,364,571
JBrowse link
G Tifab TIFA inhibitor involved_in ISO UniProtKB:Q8TF63|UniProtKB:Q92886 (PMID:23419067) RGD PMID:23419067 NCBI chr17:8,433,406...8,436,541
Ensembl chr17:8,431,635...8,436,592
JBrowse link
positive regulation of digestive system process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crh corticotropin releasing hormone IDA gut paracellular permeability RGD PMID:17234701 RGD:5491013 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
JBrowse link
positive regulation of gastric acid secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 IMP RGD PMID:11313306 RGD:1581605 NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669
JBrowse link
G Oprl1 opioid related nociceptin receptor 1 IMP RGD PMID:12007927 RGD:9835018 NCBI chr 3:168,831,934...168,839,920
Ensembl chr 3:168,834,003...168,839,920
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 IMP RGD PMID:15781048 RGD:2317117 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
JBrowse link
positive regulation of hindgut contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Oxt oxytocin/neurophysin I prepropeptide IDA RGD PMID:19258489 RGD:2304084 NCBI chr 3:117,782,650...117,783,490
Ensembl chr 3:117,782,650...117,783,490
JBrowse link
G Pawr pro-apoptotic WT1 regulator IDA RGD PMID:14724155 RGD:9835340 NCBI chr 7:43,645,028...43,725,033
Ensembl chr 7:43,645,084...43,725,028
JBrowse link
positive regulation of intestinal cholesterol absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acat2 acetyl-CoA acetyltransferase 2 involved_in ISO (MGI:5302163|PMID:22045928) RGD PMID:22045928 MGI:5302163 NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821
JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 involved_in ISO (MGI:3588413|PMID:12393855) RGD PMID:12393855 MGI:3588413 NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166
JBrowse link
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 involved_in ISS
ISO
GO_REF:0000024
(MGI:5574251|PMID:24650549)
UniProt
RGD
PMID:24650549 GO_REF:0000024 MGI:5574251 NCBI chr10:104,242,223...104,246,589
Ensembl chr10:104,242,223...104,246,589
JBrowse link
G Lpcat3 lysophosphatidylcholine acyltransferase 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:5780634|PMID:26833026)
UniProt
RGD
PMID:26833026 GO_REF:0000024 MGI:5780634 NCBI chr 4:157,468,397...157,509,889
Ensembl chr 4:157,468,290...157,509,880
JBrowse link
positive regulation of intestinal epithelial structure maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a5 solute carrier family 22 member 5 involved_in ISO
IEA
(PMID:18005709)
GO_REF:0000107
RGD
Ensembl
PMID:18005709 GO_REF:0000107 NCBI chr10:38,008,303...38,035,474
Ensembl chr10:38,008,311...38,035,309
JBrowse link
positive regulation of intestinal lipid absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prap1 proline-rich acidic protein 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:6706092|PMID:33168624)
UniProt
RGD
PMID:33168624 GO_REF:0000024 MGI:6706092 NCBI chr 1:194,883,078...194,886,874
Ensembl chr 1:194,883,078...194,886,872
JBrowse link
positive regulation of pancreatic juice secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 involved_in ISO (MGI:3822255|PMID:18806227) RGD PMID:18806227 MGI:3822255 NCBI chr 1:95,041,967...95,047,377
Ensembl chr 1:95,041,967...95,047,377
JBrowse link
G Sct secretin involved_in IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:11123201 PMID:21873635 RGD:9590235, RGD:13792537 NCBI chr 1:196,382,941...196,383,635
Ensembl chr 1:196,382,856...196,383,658
JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 IDA RGD PMID:2755938 RGD:10044250 NCBI chr18:35,870,723...35,882,693
Ensembl chr18:35,824,550...35,882,642
JBrowse link
positive regulation of saliva secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 IMP RGD PMID:18275933 RGD:5129135 NCBI chr 1:255,772,217...255,773,617
Ensembl chr 1:255,771,597...255,807,259
JBrowse link
G Aqp1 aquaporin 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:15727941), (PMID:9096382)
UniProt
RGD
PMID:9096382 PMID:15727941 GO_REF:0000024 NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690
JBrowse link
G Tac1 tachykinin, precursor 1 IDA RGD PMID:11448478 RGD:5147474 NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178
JBrowse link
G Tac4 tachykinin precursor 4 acts_upstream_of_or_within ISO (MGI:1926622|PMID:11062498) RGD PMID:11062498 MGI:1926622 NCBI chr10:80,207,824...80,216,156
Ensembl chr10:80,207,610...80,216,156
JBrowse link
G Tacr1 tachykinin receptor 1 IMP RGD PMID:11448478 RGD:5147474 NCBI chr 4:114,920,844...115,089,733
Ensembl chr 4:114,920,844...115,089,733
JBrowse link
positive regulation of small intestinal transit term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ghrl ghrelin and obestatin prepropeptide IDA RGD PMID:21874246 RGD:12910732 NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621
JBrowse link
G Ghsr growth hormone secretagogue receptor IMP RGD PMID:21874246 PMID:15890336 RGD:12910732, RGD:12907565 NCBI chr 2:110,268,489...110,271,865
Ensembl chr 2:110,268,489...110,271,865
JBrowse link
regulation of gastric acid secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hip1r huntingtin interacting protein 1 related involved_in ISO (MGI:3801545|PMID:18535670) RGD PMID:18535670 MGI:3801545 NCBI chr12:32,590,164...32,618,841
Ensembl chr12:32,590,165...32,618,734
JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:3611738|PMID:16314573), (MGI:5292649|PMID:19491250)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:16314573 PMID:19491250 GO_REF:0000024 GO_REF:0000107 MGI:3611738 MGI:5292649 NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669
JBrowse link
regulation of gastric motility term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ghrl ghrelin and obestatin prepropeptide IDA RGD PMID:23525979 RGD:12907567 NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621
JBrowse link
G Ghsr growth hormone secretagogue receptor IMP RGD PMID:23525979 RGD:12907567 NCBI chr 2:110,268,489...110,271,865
Ensembl chr 2:110,268,489...110,271,865
JBrowse link
G Tymp thymidine phosphorylase involved_in ISO (PMID:9924029) RGD PMID:9924029 NCBI chr 7:120,438,768...120,444,088
Ensembl chr 7:120,438,770...120,443,874
Ensembl chr 7:120,438,770...120,443,874
JBrowse link
regulation of hindgut contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ghsr growth hormone secretagogue receptor IMP RGD PMID:16873401 RGD:1625276 NCBI chr 2:110,268,489...110,271,865
Ensembl chr 2:110,268,489...110,271,865
JBrowse link
regulation of intestinal absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A IMP RGD PMID:22049154 RGD:8657330 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Epb41 erythrocyte membrane protein band 4.1 involved_in ISO (MGI:5496297|PMID:23460639) RGD PMID:23460639 MGI:5496297 NCBI chr 5:144,110,010...144,264,037
Ensembl chr 5:144,111,906...144,237,821
JBrowse link
regulation of intestinal cholesterol absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa1 apolipoprotein A1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:1339009|PMID:10073953)
RGD PMID:10073953 PMID:21873635 MGI:1339009, RGD:13792537 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Apoa2 apolipoprotein A2 acts_upstream_of_or_within ISO MGI:2157148 (MGI:84652|PMID:8962133) RGD PMID:8962133 MGI:84652 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355
JBrowse link
G Apoa4 apolipoprotein A4 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:2157162 (MGI:1096980|PMID:9323588)
RGD PMID:9323588 PMID:21873635 MGI:1096980, RGD:13792537 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
JBrowse link
G Apoa5 apolipoprotein A5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:46,561,180...46,563,818
Ensembl chr 8:46,561,229...46,563,816
JBrowse link
G Lep leptin acts_upstream_of_or_within ISO (MGI:2386518|PMID:12114517) RGD PMID:12114517 MGI:2386518 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
regulation of intestinal epithelial structure maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Neurod1 neuronal differentiation 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5009210|PMID:9512516)
UniProt
RGD
PMID:9512516 GO_REF:0000024 MGI:5009210 NCBI chr 3:64,360,222...64,363,526
Ensembl chr 3:64,359,395...64,363,649
JBrowse link
regulation of intestinal lipid absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dgat1 diacylglycerol O-acyltransferase 1 IMP RGD PMID:18768481 RGD:10400848 NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299
JBrowse link
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 involved_in ISS
ISO
GO_REF:0000024
(MGI:4947032|PMID:21177474)
UniProt
RGD
PMID:21177474 GO_REF:0000024 MGI:4947032 NCBI chr10:104,242,223...104,246,589
Ensembl chr10:104,242,223...104,246,589
JBrowse link
regulation of saliva secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf10 fibroblast growth factor 10 involved_in ISO (PMID:19102732) RGD PMID:19102732 NCBI chr 2:50,801,897...50,875,428
Ensembl chr 2:50,800,992...50,876,866
JBrowse link
G Oprk1 opioid receptor, kappa 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:1197118|PMID:9463367)
UniProt
RGD
PMID:9463367 GO_REF:0000024 MGI:1197118 NCBI chr 5:13,860,016...13,877,823
Ensembl chr 5:13,860,021...13,877,823
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    multicellular organismal process 8824
      system process 3339
        digestive system process 118
          regulation of digestive system process 54
            negative regulation of digestive system process + 21
            positive regulation of digestive system process + 22
            regulation of gastric acid secretion + 12
            regulation of gastric motility + 5
            regulation of hindgut contraction + 3
            regulation of intestinal absorption + 18
            regulation of intestinal epithelial structure maintenance + 2
            regulation of pancreatic juice secretion + 8
            regulation of saliva secretion + 9
            regulation of small intestinal transit + 2
Path 2
Term Annotations click to browse term
  biological_process 19492
    biological regulation 13513
      regulation of biological process 12769
        regulation of multicellular organismal process 2920
          regulation of system process 662
            regulation of digestive system process 54
              negative regulation of digestive system process + 21
              positive regulation of digestive system process + 22
              regulation of gastric acid secretion + 12
              regulation of gastric motility + 5
              regulation of hindgut contraction + 3
              regulation of intestinal absorption + 18
              regulation of intestinal epithelial structure maintenance + 2
              regulation of pancreatic juice secretion + 8
              regulation of saliva secretion + 9
              regulation of small intestinal transit + 2
paths to the root