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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of DNA methylation
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Accession:GO:0044030 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine.


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regulation of DNA methylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brca1 BRCA1, DNA repair associated involved_in IEA
ISO
GO_REF:0000107
(MGI:5009779|PMID:20820192)
Ensembl
RGD
PMID:20820192 GO_REF:0000107 MGI:5009779 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 IDA RGD PMID:22880885 RGD:9588218 NCBI chr20:3,919,623...3,936,751
Ensembl chr20:3,919,624...3,941,547
JBrowse link
G Ftx FTX transcript, XIST regulator acts_upstream_of_or_within ISO (MGI:4936795|PMID:21118898) RGD PMID:21118898 MGI:4936795 NCBI chr  X:68,588,349...68,630,338 JBrowse link
G Grhl2 grainyhead-like transcription factor 2 involved_in ISO (PMID:20938050), (PMID:23254293) RGD PMID:20938050 PMID:23254293 NCBI chr 7:68,400,287...68,530,269
Ensembl chr 7:68,400,477...68,530,258
JBrowse link
G H1f8 H1.8 linker histone involved_in ISS
ISO
GO_REF:0000024
(MGI:5559660|PMID:22868987)
UniProt
RGD
PMID:22868987 GO_REF:0000024 MGI:5559660 NCBI chr 4:148,993,133...148,998,254
Ensembl chr 4:148,993,133...148,998,254
JBrowse link
G Kdm1b lysine demethylase 1B involved_in ISO (MGI:4358629|PMID:19727073) RGD PMID:19727073 MGI:4358629 NCBI chr17:17,602,961...17,643,865
Ensembl chr17:17,602,961...17,643,800
JBrowse link
G Mbd1 methyl-CpG binding domain protein 1 IEP RGD PMID:20735989 RGD:9588647 NCBI chr18:67,869,870...67,884,501
Ensembl chr18:67,869,992...67,886,554
JBrowse link
G Mbd2 methyl-CpG binding domain protein 2 IEP RGD PMID:20735989 RGD:9588647 NCBI chr18:64,174,002...64,240,795
Ensembl chr18:64,174,002...64,240,794
JBrowse link
G Mbd3 methyl-CpG binding domain protein 3 IEP RGD PMID:20735989 RGD:9588647 NCBI chr 7:9,312,961...9,320,166
Ensembl chr 7:9,313,098...9,320,165
JBrowse link
G Mecp2 methyl CpG binding protein 2 IEP
IMP
RGD PMID:20735989 PMID:20735989 RGD:9588647, RGD:9588647 NCBI chr  X:151,781,177...151,844,687
Ensembl chr  X:151,789,930...151,844,689
JBrowse link
G Mis18a MIS18 kinetochore protein A acts_upstream_of_or_within ISO MGI:5441069 (MGI:5438906|PMID:22516971) RGD PMID:22516971 MGI:5438906 NCBI chr11:29,968,030...29,981,058
Ensembl chr11:29,967,701...29,981,062
JBrowse link
G Mphosph8 M-phase phosphoprotein 8 involved_in ISO
ISS
(PMID:20871592)
GO_REF:0000024
RGD
UniProt
PMID:20871592 GO_REF:0000024 NCBI chr15:30,800,546...30,828,415 JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 IMP RGD PMID:23260200 RGD:10413908 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Prdm14 PR/SET domain 14 acts_upstream_of_or_within ISO MGI:4441771 (MGI:5506832|PMID:23670199) RGD PMID:23670199 MGI:5506832 NCBI chr 5:6,082,163...6,092,712
Ensembl chr 5:6,082,442...6,092,712
JBrowse link
G Prmt5 protein arginine methyltransferase 5 IMP RGD PMID:22041901 RGD:9491827 NCBI chr15:27,968,893...27,978,291
Ensembl chr15:27,968,910...27,978,296
JBrowse link
G Rlf RLF zinc finger acts_upstream_of_or_within ISO MGI:5515366 (MGI:5693990|PMID:25857663) RGD PMID:25857663 MGI:5693990 NCBI chr 5:134,711,612...134,767,274
Ensembl chr 5:134,711,619...134,767,257
JBrowse link
G Tet1 tet methylcytosine dioxygenase 1 acts_upstream_of_or_within ISO (MGI:4939073|PMID:21295276) RGD PMID:21295276 MGI:4939073 NCBI chr20:25,761,042...25,840,926
Ensembl chr20:25,768,120...25,833,052
JBrowse link
G Zmpste24 zinc metallopeptidase STE24 acts_upstream_of_or_within ISO MGI:2180033 (MGI:5607719|PMID:20961378) RGD PMID:20961378 MGI:5607719 NCBI chr 5:134,627,218...134,660,360
Ensembl chr 5:134,627,229...134,660,110
JBrowse link
DNA hypermethylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnmt1 DNA methyltransferase 1 IMP RGD PMID:21682946 RGD:9588311 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
JBrowse link
G Morc1 MORC family CW-type zinc finger 1 acts_upstream_of_or_within ISO MGI:1857787 (MGI:5694015|PMID:25503965) RGD PMID:25503965 MGI:5694015 NCBI chr11:52,178,769...52,384,255
Ensembl chr11:52,178,769...52,384,255
JBrowse link
hypermethylation of CpG island term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnmt3a DNA methyltransferase 3 alpha involved_in ISO (MGI:5009774|PMID:21047779) RGD PMID:21047779 MGI:5009774 NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687
JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in ISO (MGI:5009774|PMID:21047779) RGD PMID:21047779 MGI:5009774 NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta involved_in ISO (MGI:5009774|PMID:21047779) RGD PMID:21047779 MGI:5009774 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Spi1 Spi-1 proto-oncogene involved_in ISO (PMID:20139074) RGD PMID:20139074 NCBI chr 3:77,059,744...77,093,730
Ensembl chr 3:77,073,012...77,092,393
JBrowse link
hypomethylation of CpG island term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha involved_in ISO (MGI:5009774|PMID:21047779) RGD PMID:21047779 MGI:5009774 NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032
JBrowse link
G Zmpste24 zinc metallopeptidase STE24 acts_upstream_of_or_within ISO MGI:2180033 (MGI:5607719|PMID:20961378) RGD PMID:20961378 MGI:5607719 NCBI chr 5:134,627,218...134,660,360
Ensembl chr 5:134,627,229...134,660,110
JBrowse link
negative regulation of DNA methylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnmt3l DNA methyltransferase 3 like involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:5553039|PMID:24074865)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:24074865 GO_REF:0000024 GO_REF:0000107 MGI:5553039 NCBI chr20:10,614,933...10,629,516
Ensembl chr20:10,614,934...10,629,516
JBrowse link
G Kmt2a lysine methyltransferase 2A involved_in ISO (PMID:20010842) RGD PMID:20010842 NCBI chr 8:45,116,771...45,193,320
Ensembl chr 8:45,118,814...45,193,181
JBrowse link
positive regulation of DNA methylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnmt3l DNA methyltransferase 3 like involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:5553039|PMID:24074865)
Ensembl
UniProt
RGD
PMID:24074865 GO_REF:0000024 GO_REF:0000107 MGI:5553039 NCBI chr20:10,614,933...10,629,516
Ensembl chr20:10,614,934...10,629,516
JBrowse link
G Mecp2 methyl CpG binding protein 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:23960241)
Ensembl
RGD
PMID:23960241 GO_REF:0000107 NCBI chr  X:151,781,177...151,844,687
Ensembl chr  X:151,789,930...151,844,689
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor involved_in ISO (PMID:19786833) RGD PMID:19786833 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Wt1 WT1 transcription factor acts_upstream_of ISO (PMID:23042785) RGD PMID:23042785 NCBI chr 3:91,566,540...91,613,653
Ensembl chr 3:91,567,001...91,613,643
JBrowse link
protection of DNA demethylation of female pronucleus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07015759.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07017902.2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr15:27,225,434...27,225,910 JBrowse link
G AABR07026842.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07058017.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07061871.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G Dppa3 developmental pluripotency-associated 3 involved_in IBA
ISO
ISS
PMID:21873635
(MGI:5432962|PMID:22722204), (MGI:5447615|PMID:17143267), (MGI:5465527|PMID:21407207)
GO_REF:0000024
RGD
UniProt
PMID:17143267 PMID:21407207 PMID:22722204 PMID:21873635 GO_REF:0000024 MGI:5432962 MGI:5447615 MGI:5465527, RGD:13792537 NCBI chr 4:155,851,461...155,854,845
Ensembl chr 4:155,815,296...155,854,861
JBrowse link
G Dppa3l1 developmental pluripotency associated 3-like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:56,421,825...56,422,277
Ensembl chr 8:56,421,825...56,422,277
JBrowse link
G LOC679766 similar to developmental pluripotency-associated 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    regulation of biological process 12769
      regulation of metabolic process 6740
        regulation of macromolecule metabolic process 6246
          regulation of DNA metabolic process 392
            regulation of DNA methylation 37
              DNA hypermethylation + 6
              DNA hypomethylation + 2
              negative regulation of DNA methylation 2
              positive regulation of DNA methylation 4
              protection of DNA demethylation of female pronucleus 8
Path 2
Term Annotations click to browse term
  biological_process 19492
    metabolic process 11795
      cellular metabolic process 10721
        cellular aromatic compound metabolic process 5598
          nucleobase-containing compound metabolic process 5380
            nucleic acid metabolic process 4890
              DNA metabolic process 883
                DNA modification 108
                  DNA alkylation 78
                    DNA methylation 78
                      regulation of DNA methylation 37
                        DNA hypermethylation + 6
                        DNA hypomethylation + 2
                        negative regulation of DNA methylation 2
                        positive regulation of DNA methylation 4
                        protection of DNA demethylation of female pronucleus 8
paths to the root