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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of DNA methylation
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Accession:GO:0044030 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine.


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regulation of DNA methylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BRCA1 BRCA1 DNA repair associated involved_in ISO (MGI:5009779|PMID:20820192) BHF-UCL PMID:20820192 MGI:5009779 NCBI chr17:14,197,946...14,279,064
Ensembl chr17:14,428,526...14,506,815
JBrowse link
G EHMT2 euchromatic histone lysine methyltransferase 2 ISO RGD PMID:22880885 RGD:9588218 NCBI chr 6:31,542,946...31,560,894
Ensembl chr 6:32,429,271...32,451,844
JBrowse link
G GRHL2 grainyhead like transcription factor 2 involved_in ISO (PMID:23254293)
(PMID:20938050)
UniProt PMID:20938050 PMID:23254293 NCBI chr 8:98,129,147...98,308,120
Ensembl chr 8:100,308,575...100,471,830
JBrowse link
G KDM1B lysine demethylase 1B involved_in ISO (MGI:4358629|PMID:19727073) UniProt PMID:19727073 MGI:4358629 NCBI chr 6:18,002,763...18,071,598
Ensembl chr 6:18,355,907...18,425,552
JBrowse link
G LOC100993446 histone H1.8 involved_in ISO (MGI:5559660|PMID:22868987) UniProt PMID:22868987 MGI:5559660 NCBI chr 3:126,600,616...126,609,319
Ensembl chr 3:133,952,981...133,961,243
JBrowse link
G MBD1 methyl-CpG binding domain protein 1 ISO RGD PMID:20735989 RGD:9588647 NCBI chr18:43,647,395...43,662,266
Ensembl chr18:46,996,905...47,009,831
JBrowse link
G MBD2 methyl-CpG binding domain protein 2 ISO RGD PMID:20735989 RGD:9588647 NCBI chr18:47,534,356...47,609,481 JBrowse link
G MBD3 methyl-CpG binding domain protein 3 ISO RGD PMID:20735989 RGD:9588647 Ensembl chr19:1,549,184...1,559,254 JBrowse link
G MECP2 methyl-CpG binding protein 2 ISO RGD PMID:20735989 RGD:9588647 NCBI chr  X:143,571,864...143,647,192
Ensembl chr  X:153,465,204...153,527,854
JBrowse link
G MIS18A MIS18 kinetochore protein A acts_upstream_of_or_within ISO (MGI:5438906|PMID:22516971) MGI PMID:22516971 MGI:5438906 NCBI chr21:18,635,735...18,646,611
Ensembl chr21:32,016,547...32,027,430
JBrowse link
G MPHOSPH8 M-phase phosphoprotein 8 involved_in ISO (PMID:20871592) UniProt PMID:20871592 NCBI chr13:932,620...999,853
Ensembl chr13:19,278,149...19,316,389
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 ISO RGD PMID:23260200 RGD:10413908 NCBI chr 1:201,820,355...201,867,673
Ensembl chr 1:206,812,981...206,860,356
JBrowse link
G PRDM14 PR/SET domain 14 acts_upstream_of_or_within ISO (MGI:5506832|PMID:23670199) MGI PMID:23670199 MGI:5506832 NCBI chr 8:66,578,674...66,599,360
Ensembl chr 8:68,240,741...68,260,263
JBrowse link
G PRMT5 protein arginine methyltransferase 5 ISO RGD PMID:22041901 RGD:9491827 NCBI chr14:3,737,741...3,746,646
Ensembl chr14:21,836,984...21,846,018
JBrowse link
G RLF RLF zinc finger acts_upstream_of_or_within ISO (MGI:5693990|PMID:25857663) MGI PMID:25857663 MGI:5693990 NCBI chr 1:39,448,869...39,528,061
Ensembl chr 1:40,773,638...40,852,218
JBrowse link
G TET1 tet methylcytosine dioxygenase 1 acts_upstream_of_or_within ISO (MGI:4939073|PMID:21295276) MGI PMID:21295276 MGI:4939073 NCBI chr10:65,036,313...65,168,051
Ensembl chr10:67,586,586...67,703,160
JBrowse link
G ZMPSTE24 zinc metallopeptidase STE24 acts_upstream_of_or_within ISO (MGI:5607719|PMID:20961378) MGI PMID:20961378 MGI:5607719 NCBI chr 1:39,545,264...39,589,721
Ensembl chr 1:40,869,076...40,912,747
JBrowse link
G ZNF595 zinc finger protein 595 acts_upstream_of_or_within ISO (MGI:5442238|PMID:22801370) MGI PMID:22801370 MGI:5442238 NCBI chr 4:50,243...92,219 JBrowse link
DNA hypermethylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNMT1 DNA methyltransferase 1 ISO RGD PMID:21682946 RGD:9588311 NCBI chr19:9,681,847...9,745,334
Ensembl chr19:10,342,478...10,406,972
JBrowse link
G MORC1 MORC family CW-type zinc finger 1 acts_upstream_of_or_within ISO (MGI:5694015|PMID:25503965) MGI PMID:25503965 MGI:5694015 NCBI chr 3:106,091,990...106,251,790
Ensembl chr 3:113,021,874...113,180,331
JBrowse link
hypermethylation of CpG island term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNMT3A DNA methyltransferase 3 alpha involved_in ISO (MGI:5009774|PMID:21047779) BHF-UCL PMID:21047779 MGI:5009774 NCBI chr2A:25,229,593...25,344,733
Ensembl chr2A:25,331,095...25,412,605
JBrowse link
G GSK3A glycogen synthase kinase 3 alpha involved_in ISO (MGI:5009774|PMID:21047779) BHF-UCL PMID:21047779 MGI:5009774 NCBI chr19:39,118,330...39,130,768
Ensembl chr19:47,710,197...47,726,948
JBrowse link
G GSK3B glycogen synthase kinase 3 beta involved_in ISO (MGI:5009774|PMID:21047779) BHF-UCL PMID:21047779 MGI:5009774 NCBI chr 3:116,943,205...117,215,001
Ensembl chr 3:123,861,379...124,126,771
JBrowse link
G SPI1 Spi-1 proto-oncogene involved_in ISO (PMID:20139074) UniProt PMID:20139074 NCBI chr11:47,301,245...47,326,891
Ensembl chr11:47,853,991...47,880,259
JBrowse link
hypomethylation of CpG island term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha involved_in ISO (MGI:5009774|PMID:21047779) BHF-UCL PMID:21047779 MGI:5009774 NCBI chr 3:176,182,765...176,272,024
Ensembl chr 3:184,355,785...184,441,977
JBrowse link
G ZMPSTE24 zinc metallopeptidase STE24 acts_upstream_of_or_within ISO (MGI:5607719|PMID:20961378) MGI PMID:20961378 MGI:5607719 NCBI chr 1:39,545,264...39,589,721
Ensembl chr 1:40,869,076...40,912,747
JBrowse link
negative regulation of DNA methylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNMT3L DNA methyltransferase 3 like involved_in ISO (MGI:5553039|PMID:24074865) UniProt PMID:24074865 MGI:5553039 NCBI chr21:30,503,194...30,520,237 JBrowse link
G KMT2A lysine methyltransferase 2A involved_in ISO (PMID:20010842) UniProt PMID:20010842 NCBI chr11:113,273,198...113,364,404 JBrowse link
positive regulation of DNA methylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNMT3L DNA methyltransferase 3 like involved_in ISO (MGI:5553039|PMID:24074865) UniProt PMID:24074865 MGI:5553039 NCBI chr21:30,503,194...30,520,237 JBrowse link
G MECP2 methyl-CpG binding protein 2 involved_in ISO (PMID:23960241) BHF-UCL PMID:23960241 NCBI chr  X:143,571,864...143,647,192
Ensembl chr  X:153,465,204...153,527,854
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor involved_in ISO (PMID:19786833) BHF-UCL PMID:19786833 NCBI chr 8:124,387,561...124,393,551
Ensembl chr 8:127,131,512...127,136,863
JBrowse link
G WT1 WT1 transcription factor acts_upstream_of ISO (PMID:23042785) ARUK-UCL PMID:23042785 NCBI chr11:32,349,807...32,398,494
Ensembl chr11:32,238,720...32,287,249
JBrowse link
protection of DNA demethylation of female pronucleus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DPPA3 developmental pluripotency associated 3 involved_in ISO (MGI:5432962|PMID:22722204), (MGI:5447615|PMID:17143267), (MGI:5465527|PMID:21407207) UniProt PMID:17143267 PMID:21407207 PMID:22722204 MGI:5432962 MGI:5447615 MGI:5465527 NCBI chr12:7,834,298...7,841,064 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12656
    regulation of biological process 8712
      regulation of metabolic process 5178
        regulation of macromolecule metabolic process 4754
          regulation of DNA metabolic process 362
            regulation of DNA methylation 30
              DNA hypermethylation + 6
              DNA hypomethylation + 2
              negative regulation of DNA methylation 2
              positive regulation of DNA methylation 4
              protection of DNA demethylation of female pronucleus 1
Path 2
Term Annotations click to browse term
  biological_process 12656
    metabolic process 7929
      cellular metabolic process 7257
        cellular aromatic compound metabolic process 3898
          nucleobase-containing compound metabolic process 3725
            nucleic acid metabolic process 3411
              DNA metabolic process 682
                DNA modification 102
                  DNA alkylation 70
                    DNA methylation 70
                      regulation of DNA methylation 30
                        DNA hypermethylation + 6
                        DNA hypomethylation + 2
                        negative regulation of DNA methylation 2
                        positive regulation of DNA methylation 4
                        protection of DNA demethylation of female pronucleus 1
paths to the root