Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:cell dedifferentiation
go back to main search page
Accession:GO:0043697 term browser browse the term
Definition:The process in which a specialized cell loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors.
Comment:Note that this term should be used to annotate gene products involved in dedifferentiation that occurs as part of a normal process, such as regeneration. It should not be used for dedifferentiation that occurs in an abnormal or disease state such as cancer.


show annotations for term's descendants           Sort by:
 
cell dedifferentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk6 cyclin-dependent kinase 6 involved_in ISO (PMID:12861051) RGD PMID:12861051 NCBI chr 4:27,781,728...27,969,653
Ensembl chr 4:27,785,647...27,966,398
JBrowse link
G Esrrb estrogen-related receptor beta involved_in ISS
ISO
GO_REF:0000024
(MGI:5882870|PMID:23040477)
UniProt
RGD
PMID:23040477 GO_REF:0000024 MGI:5882870 NCBI chr 6:110,360,940...110,458,406
Ensembl chr 6:110,410,141...110,455,906
JBrowse link
G Fezf1 Fez family zinc finger 1 involved_in ISO UniProtKB:Q9VQ56 (MGI:5905549|PMID:20152183) RGD PMID:20152183 MGI:5905549 NCBI chr 4:50,309,281...50,312,608
Ensembl chr 4:50,309,281...50,312,608
JBrowse link
G Fezf2 Fez family zinc finger 2 involved_in ISO UniProtKB:Q9VQ56 (MGI:5905549|PMID:20152183) RGD PMID:20152183 MGI:5905549 NCBI chr15:12,825,333...12,831,496
Ensembl chr15:12,827,707...12,831,496
JBrowse link
G Nanog Nanog homeobox involved_in ISO (MGI:5882870|PMID:23040477) RGD PMID:23040477 MGI:5882870 NCBI chr 4:155,531,906...155,539,268
Ensembl chr 4:155,531,906...155,539,268
JBrowse link
G Ncoa3 nuclear receptor coactivator 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:5440110|PMID:23019124)
UniProt
RGD
PMID:23019124 GO_REF:0000024 MGI:5440110 NCBI chr 3:162,692,176...162,788,582
Ensembl chr 3:162,692,185...162,787,548
JBrowse link
hepatocyte dedifferentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hnrnpd heterogeneous nuclear ribonucleoprotein D IEP RGD PMID:20102719 RGD:10042969 NCBI chr14:11,256,163...11,274,684
Ensembl chr14:11,256,268...11,274,578
JBrowse link
positive regulation of vascular associated smooth muscle cell dedifferentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfb platelet derived growth factor subunit B involved_in ISO
IEA
(PMID:19088079)
GO_REF:0000107
RGD
Ensembl
PMID:19088079 GO_REF:0000107 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
JBrowse link
regulation of vascular associated smooth muscle cell dedifferentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Olfm2 olfactomedin 2 involved_in IMP PMID:28062493 UniProt PMID:28062493 RGD:13441204 NCBI chr 8:21,684,307...21,762,000
Ensembl chr 8:21,681,266...21,743,338
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19634
    developmental process 6783
      dedifferentiation 9
        cell dedifferentiation 9
          cell dedifferentiation involved in phenotypic switching + 2
          hepatocyte dedifferentiation 1
paths to the root